Regional distribution and kinetics of [18F]fluciclovine (anti-[18F]FACBC), a tracer of amino acid transport, in subjects with primary prostate cancer.

abstract：PURPOSE:Focal congenital hyperinsulinism (CHI) is curable by surgery, which is why identification of the focal lesion is crucial. We aimed to determine the use of 18F-fluoro-dihydroxyphenylalanine (18F-DOPA) PET/CT vs. 68Ga-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic-acid-1-Nal3-octreotide (68Ga-DOTANOC) PET/CT...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Christiansen CD,Petersen H,Nielsen AL,Detlefsen S,Brusgaard K,Rasmussen L,Melikyan M,Ekström K,Globa E,Rasmussen AH,Hovendal C,Christesen HT

更新日期：2018-02-01 00:00:00

abstract：:In prostate cancer, confirmation of metastatic involvement of the skeleton has traditionally been achieved by bone scintigraphy, although the widespread availability of prostate-specific antigen (PSA) measurements has tended to eliminate the need for this investigation. The potential of bone scintigraphy to predict sk...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Soerdjbalie-Maikoe V,Pelger RC,Lycklama à Nijeholt GA,Arndt JW,Zwinderman AH,Bril H,Papapoulos SE,Hamdy NA

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:Physiological glucose uptake by the myocardium may hamper visualization of coronary atherosclerotic plaques in (18)F-FDG PET studies. Intracellular myocardial calcium relates to glucose influx. We assessed whether administration of a calcium channel blocker such as verapamil could decrease myocardial (18)F-FDG ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Gaeta C,Fernández Y,Pavía J,Flotats A,Artigas C,Deportos J,Geraldo L,Carrió I

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:The pattern expression score (PES), i.e., the degree to which a pathology-related pattern is present, is frequently used in FDG-brain-PET analysis and has been shown to be a powerful predictor of conversion to Alzheimer's disease (AD) in mild cognitive impairment (MCI). Since, inevitably, the PES is affected ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Blum D,Liepelt-Scarfone I,Berg D,Gasser T,la Fougère C,Reimold M,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2019-10-01 00:00:00

abstract：PURPOSE:A technique is described for accurate quantification of the specific binding ratio (SBR) in [(123)I]FP-CIT SPECT brain images. METHODS:Using a region of interest (ROI) approach, the SBR is derived from a measure of total striatal counts that takes into account the partial volume effect. Operator intervention i...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Tossici-Bolt L,Hoffmann SM,Kemp PM,Mehta RL,Fleming JS

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:Carimas (Cardiac Image Analysis System) is a new software package developed at the Turku PET Centre for the quantitation of PET studies of the heart with a broad range of tracers. The goal of this study was to assess the reproducibility of results the package provides for myocardial perfusion (MP) quantitation ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nesterov SV,Han C,Mäki M,Kajander S,Naum AG,Helenius H,Lisinen I,Ukkonen H,Pietilä M,Joutsiniemi E,Knuuti J

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:We evaluated the value of reduced global and segmental absolute stress myocardial blood flow (sMBF) quantified by [15O] water positron emission tomography (PET) for predicting cardiac events in patients with suspected obstructive coronary artery disease (CAD). METHODS:Global and segmental sMBF during adenosine...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Harjulahti E,Maaniitty T,Nammas W,Stenström I,Biancari F,Bax JJ,Knuuti J,Saraste A

更新日期：2020-11-11 00:00:00

abstract：:Orthostatic hypotension (OH) can be present in idiopathic Parkinson's disease (IPD) as well as in atypical parkinsonian syndromes such as multiple system atrophy (MSA). According to clinical tests of sympathetic nerve function and histopathological data, OH is caused by primarily postganglionic sympathetic dysfunction...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Berding G,Schrader CH,Peschel T,van den Hoff J,Kolbe H,Meyer GJ,Dengler R,Knapp WH

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Following brain cancer treatment, the capacity of anatomical MRI to differentiate neoplastic tissue from treatment-related changes (e.g., pseudoprogression) is limited. This study compared apparent diffusion coefficients (ADC) obtained by diffusion-weighted MRI (DWI) with static and dynamic parameters of O-(...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Werner JM,Stoffels G,Lichtenstein T,Borggrefe J,Lohmann P,Ceccon G,Shah NJ,Fink GR,Langen KJ,Kabbasch C,Galldiks N

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:Cervical dystonia (CD) is associated with tremor/jerks (50%) and psychiatric complaints (17-70%). The dopaminergic system has been implicated in the pathophysiology of CD in animal and imaging studies. Dopamine may be related to the motor as well as non-motor symptoms of CD. CD is associated with reduced striat...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Zoons E,Tijssen MAJ,Dreissen YEM,Speelman JD,Smit M,Booij J

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:The study aimed to compare the incidence of interstitial pneumonia on [18F]-FDG PET/CT scans between two 6-month periods: (a) the COVID-19 pandemic peak and (b) control period. Secondly, we compared the incidence of interstitial pneumonia on [18F]-FDG PET/CT and epidemiological data from the regional registry o...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Setti L,Bonacina M,Meroni R,Kirienko M,Galli F,Dalto SC,Erba PA,Bombardieri E

更新日期：2020-09-09 00:00:00

abstract：PURPOSE:To evaluate the predictive value of early and late residual (18)F-fluorodeoxyglucose (FDG) and (18)F-fluorothymidine (FLT) uptake using different SUV measurements in PET in patients with advanced non-small-cell lung cancer (NSCLC) treated with erlotinib. METHODS:We retrospectively reviewed data from 30 patient...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kobe C,Scheffler M,Holstein A,Zander T,Nogova L,Lammertsma AA,Boellaard R,Neumaier B,Ullrich RT,Dietlein M,Wolf J,Kahraman D

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:Standardized uptake value ratio (SUVr) used to quantify amyloid-β burden from amyloid-PET scans can be biased by variations in the tracer's nonspecific (NS) binding caused by the presence of cerebrovascular disease (CeVD). In this work, we propose a novel amyloid-PET quantification approach that harnesses the i...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Liu H,Nai YH,Saridin F,Tanaka T,O' Doherty J,Hilal S,Gyanwali B,Chen CP,Robins EG,Reilhac A

更新日期：2021-01-07 00:00:00

abstract：PURPOSE:To know whether mild cognitive impairment (MCI) patients will develop Alzheimer's disease (AD) dementia in very short time or remain stable is of crucial importance, also considering new experimental drugs usually tested within very short time frames. Here we combined cerebrospinal fluid (CSF) AD biomarkers and...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Santangelo R,Masserini F,Agosta F,Sala A,Caminiti SP,Cecchetti G,Caso F,Martinelli V,Pinto P,Passerini G,Perani D,Magnani G,Filippi M

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Hybrid imaging is now widely accepted in cancer imaging with increasing use of PET/CT in clinical practice. The advantages of MRI compared to CT with respect to radiation exposure and soft-tissue lesion contrast, as well as the possibility of performing more sophisticated assessment of tissue chemistry, ha...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hicks RJ,Lau EW

更新日期：2009-03-01 00:00:00

abstract：:As measurement of glomerular filtration rate (GFR) is now generally the responsibility of departments of nuclear medicine, it is important for nuclear medicine physicians and scientists to understand the pharmacokinetics of the indicators and radiotracers that are used, generally known as filtration markers. The singl...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Peters AM

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:In vivo Alzheimer's disease (AD) biomarkers for tau pathology are cerebrospinal fluid (CSF) phosphorylated tau (p-tau) and [18F]flortaucipir positron emission tomography (PET). Our aim was to assess associations between CSF p-tau with [18F]flortaucipir PET and the associations of both tau biomarkers with cognit...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Wolters EE,Ossenkoppele R,Verfaillie SCJ,Coomans EM,Timmers T,Visser D,Tuncel H,Golla SSV,Windhorst AD,Boellaard R,van der Flier WM,Teunissen CE,Scheltens P,van Berckel BNM

更新日期：2020-11-01 00:00:00

abstract：:The aim of this study was to describe the anatomical structures that show uptake of the somatostatin analogue octreotide in patients with thyroid-associated orbitopathy (TAO). The study population comprised a series of 20 TAO patients attending the out-patient thyroid clinic and 12 patients presenting head or neck tum...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kainz H,Bale R,Donnemiller E,Gabriel M,Kovacs P,Decristoforo C,Moncayo R

更新日期：2003-08-01 00:00:00

abstract：PURPOSE:We compared left ventricular (LV) ejection fraction obtained by gated SPECT with that obtained by equilibrium radionuclide angiocardiography in a large cohort of patients. METHODS:Within 1 week, 514 subjects with suspected or known coronary artery disease underwent same-day stress-rest (99m)Tc-sestamibi gated ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Acampa W,Caprio MG,Nicolai E,Liuzzi R,De Luca S,Capasso E,Luongo L,Petretta M,Cuocolo A

更新日期：2010-02-01 00:00:00

abstract：PURPOSE:Anti-PD-1/PD-L1 blockade can restore tumour-specific T-cell immunity and is an emerging therapy in non-small-cell lung cancer (NSCLC). We investigated the correlation between 18F-FDG PET/CT-based markers and tumour tissue expression of PD-L1, necrosis and clinical outcome in patients receiving checkpoint inhibi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Jreige M,Letovanec I,Chaba K,Renaud S,Rusakiewicz S,Cristina V,Peters S,Krueger T,de Leval L,Kandalaft LE,Nicod-Lalonde M,Romero P,Prior JO,Coukos G,Schaefer N

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:Diagnostic imaging modalities have moderate sensitivity for the identification of lymph node (LN) metastases in prostate cancer (PCa) patients. Mapping the lymphatic drainage from the prostate can help to identify the LNs directly draining from the tumour (sentinel nodes (SNs)); the LNs stated to have the highe...

journal_title：European journal of nuclear medicine and molecular imaging

authors： de Korne CM,Wit EM,de Jong J,Valdés Olmos RA,Buckle T,van Leeuwen FWB,van der Poel HG

更新日期：2019-11-01 00:00:00

abstract：PURPOSE:In children with Hodgkin's disease and non-Hodgkin's lymphoma, the ability of (18)F-fluoro-2-deoxy-D-glucose PET/CT and conventional imaging (CI) to detect malignant lesions and predict poor lesion response to therapy was assessed and compared. METHODS:A retrospective review of findings reported on PET/CT and ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： London K,Cross S,Onikul E,Dalla-Pozza L,Howman-Giles R

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:The folate receptor (FR) is frequently overexpressed in a variety of tumor types and, hence, an interesting target for radionuclide therapy. The aim of this study was to evaluate a new class of albumin-binding radioconjugates comprising 5-methyltetrahydrofolate (5-MTHF) as a targeting agent and to compare their...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Guzik P,Benešová M,Ratz M,Monné Rodríguez JM,Deberle LM,Schibli R,Müller C

更新日期：2020-10-15 00:00:00

abstract：:The trade-off between resolution and count sensitivity dominates the performance of standard gamma cameras and dictates the need for relatively high doses of radioactivity of the used radiopharmaceuticals in order to limit image acquisition duration. The introduction of cadmium-zinc-telluride (CZT)-based cameras may o...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Agostini D,Marie PY,Ben-Haim S,Rouzet F,Songy B,Giordano A,Gimelli A,Hyafil F,Sciagrà R,Bucerius J,Verberne HJ,Slart RH,Lindner O,Übleis C,Hacker M,Cardiovascular Committee of the European Association of Nuclear Medicine (E

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To assess the radiation dosimetry and biodistribution of (99m)Tc-labeled ethylene dicysteine deoxyglucose ((99m)Tc-EC-DG) in patients with non-small-cell lung cancer (NSCLC). METHODS:Serial whole-body scans were acquired 0, 2, 4, 6 and 24 h after injection of (99m)Tc-EC-DG (925 MBq) in seven NSCLC patients. Ra...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Schechter NR,Erwin WD,Yang DJ,Kim EE,Munden RF,Forster K,Taing LC,Cox JD,Macapinlac HA,Podoloff DA

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:The specific binding ratio (SBR) of 123I-FP-CIT (FP-CIT) in the putamen decreases with age by about 5% per decade and most likely is about 10% higher in females. However, the clinical utility of age and sex correction of the SBR is still a matter of debate. This study tested the impact of age and sex correction...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Schmitz-Steinkrüger H,Lange C,Apostolova I,Mathies FL,Frings L,Klutmann S,Hellwig S,Meyer PT,Buchert R

更新日期：2020-10-31 00:00:00

abstract：PURPOSE:The aim of the study was to determine the accuracy of non-rigid nine-parameter image registrations based on 153Gd transmission computed tomography (TCT) images as compared with those based on 99mTc-ethyl cysteinate dimer (ECD) images and to assess whether normalised mutual information (NMI) or count difference ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Jacobs F,Koole M,Goethals I,Van de Wiele C,Ham H,Dierckx R

更新日期：2004-11-01 00:00:00

abstract：PURPOSE:Low-grade joint infections are characterized by infiltration of granulocytes, which mediate aspects of inflammatory changes. We evaluated retrospectively the contribution of SPECT/CT as an addition to planar scintigraphy with (99m)Tc-labelled antigranulocyte antibodies for diagnosing and localizing low-grade jo...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Graute V,Feist M,Lehner S,Haug A,Müller PE,Bartenstein P,Hacker M

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:Dual-isotope simultaneous acquisition single-photon emission computed tomography (DISA SPECT) with 18F-fluorodeoxyglucose (FDG) and (99m)Tc-sestamibi appears attractive for the detection of viable myocardium because it permits simultaneous assessment of glucose utilisation and perfusion. Another potential benef...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Matsunari I,Kanayama S,Yoneyama T,Matsudaira M,Nakajima K,Taki J,Nekolla SG,Tonami N,Hisada K

更新日期：2005-02-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the clinical usefulness of [(11)C]choline positron emission tomography (PET)/CT in comparison with bone scintigraphy (BS) in detecting bone metastases (BM) of patients with biochemical progression after radical treatment for prostate cancer (PCa). METHODS:Seventy-eight con...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Picchio M,Spinapolice EG,Fallanca F,Crivellaro C,Giovacchini G,Gianolli L,Messa C

更新日期：2012-01-01 00:00:00