18F-DOPA PET/CT and 68Ga-DOTANOC PET/CT scans as diagnostic tools in focal congenital hyperinsulinism: a blinded evaluation.

abstract：PURPOSE:To assess the value of SPECT/CT in patients with carpal boss (CB). METHODS:In 24 wrists with CB (18 right-sided, 6 left-sided) in 21 patients, planar images and SPECT/CT images were obtained. Three patients had bilateral CB. The grade of uptake (0 absent, 1 low, 2 moderate, 3 high) on planar imaging and SPECT/...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bhure U,Hug U,Huellner MW,Grünig H,Zander A,Del Sol Pérez Lago M,Strobel K

更新日期：2015-11-01 00:00:00

abstract：:Vagus nerve stimulation (VNS) has gained recognition as a treatment for refractory epilepsies where surgical treatment is not possible. While it appears that this treatment is effective in some patients, the mechanism of action is not clearly understood. The purpose of this study was to clarify findings of other posit...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Barnes A,Duncan R,Chisholm JA,Lindsay K,Patterson J,Wyper D

更新日期：2003-02-01 00:00:00

abstract：PURPOSE:The role of brain FDG-PET in patients with lung cancer and brain metastases remains unclear. Here, we sought to determine the prognostic significance of whole-body PET/CT plus brain PET/MR in predicting the time to neurological progression (nTTP) and overall survival (OS) in this patient group. METHODS:Of 802 ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ho KC,Toh CH,Li SH,Liu CY,Yang CT,Lu YJ,Su TP,Wang CW,Yen TC

更新日期：2019-02-01 00:00:00

abstract：PURPOSE:To assess diagnostic accuracy of (18)F-FDG PET/CT at 3 months for the detection of local recurrence after radiofrequency ablation (RFA) of lung metastases. METHODS:The PET/CT scan at 3 months was compared with a baseline PET/CT scan from a maximum of 2 months before RFA, with the reference standard as recurren...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bonichon F,Palussière J,Godbert Y,Pulido M,Descat E,Devillers A,Meunier C,Leboulleux S,de Baère T,Galy-Lacour C,Lagoarde-Segot L,Cazeau AL

更新日期：2013-12-01 00:00:00

abstract：RATIONALE:In Parkinson's disease (PD), spatial covariance analysis of 18F-FDG PET data has consistently revealed a characteristic PD-related brain pattern (PDRP). By quantifying PDRP expression on a scan-by-scan basis, this technique allows objective assessment of disease activity in individual subjects. We provide a f...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Meles SK,Renken RJ,Pagani M,Teune LK,Arnaldi D,Morbelli S,Nobili F,van Laar T,Obeso JA,Rodríguez-Oroz MC,Leenders KL

更新日期：2020-02-01 00:00:00

abstract：:This paper updates the information on the prevalence of the disorders induced by iodine deficiency (IDD) in Europe. Thirty-two European countries were still affected by mild to severe iodine deficiency in the late 1990s. The most severely affected countries were in Eastern Europe, including Central Asia, but Western E...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Delange F

更新日期：2002-08-01 00:00:00

abstract：PURPOSE:Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a myocardial disease that predominantly affects the right ventricle (RV). Its hallmark feature is fibro-fatty replacement of RV myocardium. However, patchy inflammatory infiltrates in the RV are also consistently reported using autopsy and my...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Campian ME,Verberne HJ,Hardziyenka M,de Groot EA,van Moerkerken AF,van Eck-Smit BL,Tan HL

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:We investigated the performance of the Inveon small-animal PET/SPECT/CT system and compared the imaging capabilities of the SPECT and PET components. METHODS:For SPECT, the energy resolution, tomographic spatial resolution and system sensitivity were evaluated with a (99m)Tc solution using a single pinhole col...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Magota K,Kubo N,Kuge Y,Nishijima K,Zhao S,Tamaki N

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:The aim of this study was to develop a methodology for the comparison of pathology specimens after prostatectomy (post-S) with PET images obtained before surgery (pre-S). This method was used to evaluate the merit of (11)C-choline PET/CT for delineation of gross tumour volume (GTV) in prostate cancer (PC). MET...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Grosu AL,Weirich G,Wendl C,Prokic V,Kirste S,Geinitz H,Souvatzoglou M,Gschwend JE,Schwaiger M,Molls M,Weber WA,Treiber U,Krause BJ

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:To determine whether the metabolic features of breast tumours differ among molecular subtypes. METHODS:This prospective study included 168 women diagnosed with locally advanced breast cancer. PET/CT was requested in the initial staging before neoadjuvant treatment (multicentre study, FISCAM grant). All patient...

journal_title：European journal of nuclear medicine and molecular imaging

authors： García Vicente AM,Soriano Castrejón Á,León Martín A,Chacón López-Muñiz I,Muñoz Madero V,Muñoz Sánchez Mdel M,Palomar Muñoz A,Espinosa Aunión R,González Ageitos A

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:We developed and tested a single acquisition rest (99m)Tc-sestamibi/stress (201)Tl dual isotope protocol (SDI) with the intention of improving the clinical workflow and patient comfort of myocardial perfusion single photon emission computed tomography (SPECT). METHODS:The technical feasibility of SDI was evalu...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Dey T,Backus BE,Romijn RL,Wieczorek H,Verzijlbergen JF

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:When deciding on therapy, FDG PET/CT-positive results should be confirmed by histology if possible. We evaluated the impact of percutaneous PET/CT-guided biopsies on histological confirmation of PET/CT-positive lesions. METHODS:We prospectively evaluated 126 patients who had undergone a PET/CT scan with posi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Cerci JJ,Pereira Neto CC,Krauzer C,Sakamoto DG,Vitola JV

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:Reduced presynaptic dopaminergic activity plays an important role in the development of levodopa-induced dyskinesia (LID) in Parkinson's disease (PD). In this study, we investigated whether dopaminergic function in the nigrostriatal system is associated with the timing of LID onset. METHODS:From among 412 drug...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Yoo HS,Chung SJ,Chung SJ,Moon H,Oh JS,Kim JS,Hong JY,Ye BS,Sohn YH,Lee PH

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:Lipid nanocapsules (LNC) entrapping lipophilic complexes of (188)Re ((188)Re(S(3)CPh)(2)(S(2)CPh) [(188)Re-SSS]) were investigated as a novel radiopharmaceutical carrier for internal radiation therapy of malignant gliomas. The present study was designed to evaluate the efficacy of intra-cerebral administration ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Allard E,Hindre F,Passirani C,Lemaire L,Lepareur N,Noiret N,Menei P,Benoit JP

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:Physiological glucose uptake by the myocardium may hamper visualization of coronary atherosclerotic plaques in (18)F-FDG PET studies. Intracellular myocardial calcium relates to glucose influx. We assessed whether administration of a calcium channel blocker such as verapamil could decrease myocardial (18)F-FDG ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Gaeta C,Fernández Y,Pavía J,Flotats A,Artigas C,Deportos J,Geraldo L,Carrió I

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:Imaging probes/biomarkers that are correlated with molecular or microenvironmental alterations in tumors have been used not only in diagnosing cancer but also in assessing the efficacy of cancer treatment. We evaluated the early response of hepatocellular carcinoma (HCC) to radiation treatment using T2-weighted...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Chung YH,Yu CF,Chiu SC,Chiu H,Hsu ST,Wu CR,Yang CL,Hong JH,Yen TC,Chen FH

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:18-fluorodeoxyglucose positron emission tomography combined with computed tomography (FDG-PET/CT) is increasingly used to evaluate treatment response in head and neck squamous cell carcinoma (HNSCC). This analysis assessed the diagnostic value of FDG-PET/CT in detecting nodal disease within 6 months after treat...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Helsen N,Van den Wyngaert T,Carp L,Stroobants S

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To determine if preoperative [(18)F]FDG-PET/CT imaging has prognostic significance in patients with uterine cervical cancer. METHODS:Patients with FIGO stage IB to IIA cervical cancer were imaged with integrated FDG PET/CT before radical surgery. The relationship between the maximum standardized uptake value (...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Chung HH,Nam BH,Kim JW,Kang KW,Park NH,Song YS,Chung JK,Kang SB

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:This study aimed at identifying prior therapy dosimetric parameters using 99mTc-labeled macro-aggregates of albumin (MAA) that are associated with contralateral hepatic hypertrophy occurring after unilobar radioembolization of hepatocellular carcinoma (HCC) performed with 90Y-loaded glass microspheres. METHODS...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Palard X,Edeline J,Rolland Y,Le Sourd S,Pracht M,Laffont S,Lenoir L,Boudjema K,Ugen T,Brun V,Mesbah H,Haumont LA,Loyer P,Garin E

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:The relationship between tumor metabolism and stage, subcutaneous and visceral fat thickness, and their glucose metabolism and overall survival in patients recently diagnosed with pancreatic carcinoma was assessed. METHODS:Thirty-eight consecutive patients were studied. Subcutaneous fat thickness (SFT), viscer...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Van de Wiele C,Van Vlaenderen M,D'Hulst L,Delcourt A,Copin D,De Spiegeleer B,Maes A

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:Facilitation of the ability of neuronal lineages derived from transplanted stem cells to differentiate is essential to improve the low efficacy of neuronal differentiation in stem cell therapy in vivo. Neurogenin 1 (Ngn1), a basic helix-loop-helix factor, has been used as an activator of neuronal differentiatio...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Oh HJ,Hwang DW,Youn H,Lee DS

更新日期：2013-10-01 00:00:00

abstract：PURPOSE:Penile cancer (PC) is a rare neoplasm with an aggressive behavior and variable prognosis. Lymph node (LN) involvement and pathological features of the primary lesion have been proven to be the most important survival factors. Positron emission tomography/computed tomography with fluorodeoxyglucose labelled with...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Salazar A,Júnior EP,Salles PGO,Silva-Filho R,Reis EA,Mamede M

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:This study was designed to determine safety, tolerability, and radiation burden of a [(68)Ga]NODAGA-RGD-PET for imaging integrin αvβ3 expression in patients with hepatocellular carcinoma (HCC) and liver cirrhosis. Moreover, metabolic stability and biokinetic data were compiled. METHODS:After injection of 154-1...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Haubner R,Finkenstedt A,Stegmayr A,Rangger C,Decristoforo C,Zoller H,Virgolini IJ

更新日期：2016-10-01 00:00:00

abstract：PURPOSE:The objective of this article is to present a new method for the diagnosis of insulinoma with the use of [Lys(40)(Ahx-HYNIC-(99m)Tc/EDDA)NH2]-exendin-4. METHODS:Studies were performed in 11 patients with negative results of all available non-isotopic diagnostic methods (8 with symptoms of insulinoma, 2 with ma...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sowa-Staszczak A,Pach D,Mikołajczak R,Mäcke H,Jabrocka-Hybel A,Stefańska A,Tomaszuk M,Janota B,Gilis-Januszewska A,Małecki M,Kamiński G,Kowalska A,Kulig J,Matyja A,Osuch C,Hubalewska-Dydejczyk A

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To determine clinical predictors and accuracy of (123)I-FP-CIT SPECT imaging in the differentiation of drug-induced parkinsonism (DIP) and Parkinson's disease (PD). METHODS:Several clinical features and (123)I-FP-CIT SPECT images in 32 patients with DIP, 25 patients with PD unmasked by antidopaminergic drugs (...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Diaz-Corrales FJ,Sanz-Viedma S,Garcia-Solis D,Escobar-Delgado T,Mir P

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:PET is a powerful tool for assessing targeted therapy. Since (18)F-FDG shows a potential prognostic value in medullary thyroid carcinoma (MTC), this study evaluated (18)F-FDG PET alone and combined with morphological and biomarker evaluations as a surrogate marker of overall survival (OS) in patients with progr...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Salaun PY,Campion L,Ansquer C,Frampas E,Mathieu C,Robin P,Bournaud C,Vuillez JP,Taieb D,Rousseau C,Drui D,Mirallié E,Borson-Chazot F,Goldenberg DM,Chatal JF,Barbet J,Kraeber-Bodéré F

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:Point-spread function (PSF) or PSF + time-of-flight (TOF) reconstruction may improve lesion detection in oncologic PET, but can alter quantitation resulting in variable standardized uptake values (SUVs) between different PET systems. This study aims to validate a proprietary software tool (EQ.PET) to harmonize ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Quak E,Le Roux PY,Hofman MS,Robin P,Bourhis D,Callahan J,Binns D,Desmonts C,Salaun PY,Hicks RJ,Aide N

更新日期：2015-12-01 00:00:00

abstract：:An ordered subsets (OS) reconstruction algorithm based on the median root prior (MRP) and inter-update median filtering was implemented for the reconstruction of low count statistics transmission (TR) scans. The OS-MRP-TR algorithm was evaluated using an experimental phantom, simulating positron emission tomography (P...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bettinardi V,Alenius S,Numminen P,Teräs M,Gilardi MC,Fazio F,Ruotsalainen U

更新日期：2003-02-01 00:00:00

abstract：PURPOSE:Previous functional neuroimaging studies suggest that selective aspects of the brain serotonin (5-HT) system change during the aging process. Here, we assessed the effects of aging on the brain regional alpha-[(11)C]methyl-L: -tryptophan (alpha-[(11)C]MTrp) trapping rate constant (K*; microl.g(-1).min(-1)), whi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Rosa-Neto P,Benkelfat C,Sakai Y,Leyton M,Morais JA,Diksic M

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:Neuroinflammation is involved in neurological disorders through the activation of microglial cells. Imaging of neuroinflammation with radioligands for the translocator protein (18 kDa) (TSPO) could prove to be an attractive biomarker for disease diagnosis and therapeutic evaluation. The indoleacetamide-derived ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Chauveau F,Boutin H,Van Camp N,Thominiaux C,Hantraye P,Rivron L,Marguet F,Castel MN,Rooney T,Benavides J,Dollé F,Tavitian B

更新日期：2011-03-01 00:00:00