188Re-loaded lipid nanocapsules as a promising radiopharmaceutical carrier for internal radiotherapy of malignant gliomas.

abstract：PURPOSE:Sympathetic nervous system (SNS) hyperactivity is a salient characteristic of chronic heart failure (HF) and contributes to the progression of the disease. Iodine-123 meta-iodobenzylguanidine (123I-mIBG) imaging has been successfully used to assess cardiac SNS activity in HF patients and to predict prognosis. I...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Rengo G,Pagano G,Vitale DF,Formisano R,Komici K,Petraglia L,Parisi V,Femminella GD,de Lucia C,Paolillo S,Cannavo A,Attena E,Pellegrino T,Dellegrottaglie S,Memmi A,Trimarco B,Cuocolo A,Filardi PP,Leosco D,Ferrara N

更新日期：2016-12-01 00:00:00

abstract：:Techniques from the field of artificial intelligence, and more specifically machine (deep) learning methods, have been core components of most recent developments in the field of medical imaging. They are already being exploited or are being considered to tackle most tasks, including image reconstruction, processing (...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Visvikis D,Cheze Le Rest C,Jaouen V,Hatt M

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:Standardized uptake value ratio (SUVr) used to quantify amyloid-β burden from amyloid-PET scans can be biased by variations in the tracer's nonspecific (NS) binding caused by the presence of cerebrovascular disease (CeVD). In this work, we propose a novel amyloid-PET quantification approach that harnesses the i...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Liu H,Nai YH,Saridin F,Tanaka T,O' Doherty J,Hilal S,Gyanwali B,Chen CP,Robins EG,Reilhac A

更新日期：2021-01-07 00:00:00

abstract：PURPOSE:In about 30% of patients treated with neoadjuvant chemoradiotherapy (nCRT) followed by surgical resection for locally advanced oesophageal cancer no vital tumour is found in the resection specimen. Accurate clinical response assessment is critical if deferral from surgery is considered in complete responders. O...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Vollenbrock SE,Voncken FEM,Lambregts DMJ,Maas M,Donswijk ML,Vegt E,Ter Beek LC,van Dieren JM,van Sandick JW,Aleman BMP,Beets-Tan RGH,Bartels-Rutten A

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:Noninvasive markers of disease activity in patients with idiopathic pulmonary fibrosis (IPF) are lacking. We performed this study to investigate the reproducibility of pulmonary (18)F-FDG PET/CT in patients with IPF. METHODS:The study group comprised 13 patients (11 men, 2 women; mean age 71.1 ± 9.9 years) wit...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Win T,Lambrou T,Hutton BF,Kayani I,Screaton NJ,Porter JC,Maher TM,Endozo R,Shortman RI,Lukey P,Groves AM

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:No data are yet available in the literature concerning 3-D [(123)I]-meta-iodobenzylguanidine ([(123)I]-MIBG) kinetics in vivo. In this study we investigated the feasibility of dynamic 3-D [(123)I]-MIBG kinetic analysis using a CZT ultrafast camera. METHODS:The study group comprised 16 patients consecutively sc...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Tinti E,Positano V,Giorgetti A,Marzullo P

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:This study was performed to demonstrate that the results obtained with a calibration phantom could be used as a tool for standardizing measurement of heart to mediastinum (H/M) ratio in cardiac metaiodobenzylguanidine (MIBG) imaging. METHODS:Images of the phantom containing (123)I-MIBG were acquired on the cam...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nakajima K,Okuda K,Matsuo S,Yoshita M,Taki J,Yamada M,Kinuya S

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:Prostate cancer is difficult to visualise in its early stages using current imaging technology. The present study aimed to clarify the utility of 11C-choline PET for localising and evaluating cancer lesions in patients with prostate cancer by conducting a prospective comparison with magnetic resonance (MR) imag...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Yamaguchi T,Lee J,Uemura H,Sasaki T,Takahashi N,Oka T,Shizukuishi K,Endou H,Kubota Y,Inoue T

更新日期：2005-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to compare planning target volume (PTV) defined on respiratory-gated positron emission tomography (PET)/CT (RG-PET/CT) to PTV based on ungated free-breathing CT and to evaluate if RG-PET/CT can be useful to personalize PTV by tailoring the target volume to the lesion motion in lung can...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Guerra L,Meregalli S,Zorz A,Niespolo R,De Ponti E,Elisei F,Morzenti S,Brenna S,Crespi A,Gardani G,Messa C

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:The intra-arterial administration of 90Y microspheres is a new palliative treatment option for unresectable liver metastases. The aim of this study was to quantitatively assess changes in FDG uptake and tumour size following 90Y microsphere treatment (SIR-Spheres) using 18F-fluorodeoxyglucose (FDG) PET/CT imagi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bienert M,McCook B,Carr BI,Geller DA,Sheetz M,Tutor C,Amesur N,Avril N

更新日期：2005-07-01 00:00:00

abstract：:Positron emission tomography (PET) has now gained a place in the management of patients with cancer, including those with Hodgkin's disease and non-Hodgkin's lymphoma. Restaging studies and those addressing the monitoring of response to treatment are especially in focus. Most of the knowledge gained has been achieved ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Visvikis D,Ell PJ

更新日期：2003-06-01 00:00:00

abstract：PURPOSE:The purpose of this study was to design a fully automatic computer-assisted diagnostic system for early- and late-onset mild Alzheimer's disease (AD). METHODS:Glucose metabolic images were obtained from mild AD patients and normal controls using positron emission tomography (PET) and( 18)F-fluorodeoxyglucose (...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ishii K,Kono AK,Sasaki H,Miyamoto N,Fukuda T,Sakamoto S,Mori E

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:It has been shown that some primary human tumours and their metastases, including prostate and breast tumours, overexpress gastrin-releasing peptide (GRP) receptors. Bombesin (BN) is a neuropeptide with a high affinity for these GRP receptors. We demonstrated successful scintigraphic visualisation of BN recepto...

journal_title：European journal of nuclear medicine and molecular imaging

authors： de Visser M,Bernard HF,Erion JL,Schmidt MA,Srinivasan A,Waser B,Reubi JC,Krenning EP,de Jong M

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:Focal congenital hyperinsulinism (CHI) is curable by surgery, which is why identification of the focal lesion is crucial. We aimed to determine the use of 18F-fluoro-dihydroxyphenylalanine (18F-DOPA) PET/CT vs. 68Ga-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic-acid-1-Nal3-octreotide (68Ga-DOTANOC) PET/CT...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Christiansen CD,Petersen H,Nielsen AL,Detlefsen S,Brusgaard K,Rasmussen L,Melikyan M,Ekström K,Globa E,Rasmussen AH,Hovendal C,Christesen HT

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:Extracapsular spread (ECS) to the cervical lymph nodes is a major adverse prognostic factor in oral cavity squamous cell carcinoma (OSCC). We prospectively examined the value of FDG PET immediately before postoperative radiotherapy/concurrent chemoradiotherapy (pre-RT/CCRT PET) to detect residual/relapsing dise...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Liao CT,Fan KH,Lin CY,Wang HM,Huang SF,Chen IH,Kang CJ,Ng SH,Hsueh C,Lee LY,Lin CH,Yen TC

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:Twelve years ago a meta-analysis evaluated the diagnostic performance of (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in assessing musculoskeletal soft tissue lesions (MsSTL). Currently, PET/CT has substituted PET imaging; however, there has not been any published meta-analysis on the use o...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Etchebehere EC,Hobbs BP,Milton DR,Malawi O,Patel S,Benjamin RS,Macapinlac HA

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:To investigate the value of 68Ga-HBED-CC PSMA (68Ga-PSMA) PET/CT for response assessment in metastatic castration-sensitive and castration-resistant prostate cancer (mCSPC and mCRPC) during docetaxel chemotherapy. METHODS:68Ga-PSMA PET/CT was performed in seven mCSPC patients before and after six cycles of upf...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Seitz AK,Rauscher I,Haller B,Krönke M,Luther S,Heck MM,Horn T,Gschwend JE,Schwaiger M,Eiber M,Maurer T

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:Medial temporal impairment can be detected clinically and by morphological imaging during Alzheimer's disease (AD), but the existence of a functional impairment in this area seems to be less well established. Yet such functional impairment is classically found in other degenerative cortical dementias, such as t...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Basely M,Ceccaldi M,Boyer L,Mundler O,Guedj E

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:Pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) is commonly accepted as the gold standard to assess outcome after NAC in breast cancer patients. 18F-Fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) has unique value in tumor staging, predicting prognosis, and eval...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Li P,Wang X,Xu C,Liu C,Zheng C,Fulham MJ,Feng D,Wang L,Song S,Huang G

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:4'-[Methyl-11C] thiothymidine (4DST) incorporates into DNA directly and is a PET tracer used for cell proliferation imaging. The aim of this study was to evaluate the prediction of prognosis with pretreatment 4DST PET/CT compared to fluorodeoxyglucose (FDG) PET/CT in patients with esophageal cancer. METHODS:In...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hotta M,Minamimoto R,Toyohara J,Nohara K,Nakajima K,Takase K,Yamada K

更新日期：2021-01-12 00:00:00

abstract：PURPOSE:There are controversial debates if patients with Hürthle cell carcinoma, also known as oxyphilic or oncocytic cell follicular thyroid carcinoma, have a poorer outcome. In this study, we systematically evaluated the clinical outcome in a large patient cohort following thyroidectomy and initial I-131 radioactive ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Wenter V,Albert NL,Unterrainer M,Ahmaddy F,Ilhan H,Jellinek A,Knösel T,Bartenstein P,Spitzweg C,Lehner S,Todica A

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:The aim of this prospective study is to evaluate the combined use of fluorine-18 fluorodeoxyglucose ((18) F-FDG) and fluorine-18 sodium fluoride ((18) F-NaF) PET/CT in the skeletal assessment of patients with multiple myeloma (MM) and to compare the efficacy of these two PET tracers regarding detection of mye...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sachpekidis C,Goldschmidt H,Hose D,Pan L,Cheng C,Kopka K,Haberkorn U,Dimitrakopoulou-Strauss A

更新日期：2014-07-01 00:00:00

abstract：:Serotonin-1A (5-HT(1A)) receptors are implicated in neurochemical mechanisms underlying anxiety and depression and their treatment. Animal studies have suggested that 4-(2'-methoxyphenyl)-1-[2'-[ N-(2"-pyridinyl)- p-[(18)F]fluorobenzamido] ethyl] piperazine ( p-MPPF) may be a suitable positron emission tomography (PET...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sanabria-Bohórquez SM,Biver F,Damhaut P,Wikler D,Veraart C,Goldman S

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:In this study, the potential contribution of Dixon-based MR imaging with a rapid low-resolution breath-hold sequence, which is a technique used for MR-based attenuation correction (AC) for MR/positron emission tomography (PET), was evaluated for anatomical correlation of PET-positive lesions on a 3T clinical sc...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Eiber M,Martinez-Möller A,Souvatzoglou M,Holzapfel K,Pickhard A,Löffelbein D,Santi I,Rummeny EJ,Ziegler S,Schwaiger M,Nekolla SG,Beer AJ

更新日期：2011-09-01 00:00:00

abstract：:This review describes the properties of available and emerging radiation detector and read-out technologies and discusses how they may affect PET scanner performance. After a general introduction, there is a section in which the physical properties of several different detector scintillators are compared. This is foll...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Humm JL,Rosenfeld A,Del Guerra A

更新日期：2003-11-01 00:00:00

abstract：PURPOSE:The purpose of this prospective study was to evaluate the usefulness of (18)F-fluorodeoxyglucose (FDG) and (11)C-choline positron emission tomography (PET)/computed tomography (CT) for detecting recurrences of advanced head and neck cancer after combined intra-arterial chemotherapy and radiotherapy. Additionall...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ito K,Yokoyama J,Kubota K,Morooka M,Shiibashi M,Matsuda H

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:Dual-isotope simultaneous acquisition single-photon emission computed tomography (DISA SPECT) with 18F-fluorodeoxyglucose (FDG) and (99m)Tc-sestamibi appears attractive for the detection of viable myocardium because it permits simultaneous assessment of glucose utilisation and perfusion. Another potential benef...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Matsunari I,Kanayama S,Yoneyama T,Matsudaira M,Nakajima K,Taki J,Nekolla SG,Tonami N,Hisada K

更新日期：2005-02-01 00:00:00

abstract：PURPOSE:Salvage of young patients with follicular lymphoma (FL) after R-CHOP includes salvage immunochemotherapy followed by autologous stem cell transplantation (ASCT). Previous studies dealing with relapsed Hodgkin lymphoma have shown the prognostic value of PET/CT prior to ASCT. METHODS:We retrospectively analysed ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Alcantara M,Dupuis J,Mareschal S,Julian A,Cottereau AS,Becker S,Dubois S,Oberic L,Huynh A,Meignan M,Laurent G,Tilly H,Haioun C,Ysebaert L

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:Multi-centre trials are an important part of proving the efficacy of procedures, drugs and interventions. Imaging components in such trials are becoming increasingly common; however, without sufficient control measures the usefulness of these data can be compromised. This paper describes a framework for perform...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Dickson JC,Tossici-Bolt L,Sera T,de Nijs R,Booij J,Bagnara MC,Seese A,Koulibaly PM,Akdemir UO,Jonsson C,Koole M,Raith M,Lonsdale MN,George J,Zito F,Tatsch K

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To assess the radiation dosimetry and biodistribution of (99m)Tc-labeled ethylene dicysteine deoxyglucose ((99m)Tc-EC-DG) in patients with non-small-cell lung cancer (NSCLC). METHODS:Serial whole-body scans were acquired 0, 2, 4, 6 and 24 h after injection of (99m)Tc-EC-DG (925 MBq) in seven NSCLC patients. Ra...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Schechter NR,Erwin WD,Yang DJ,Kim EE,Munden RF,Forster K,Taing LC,Cox JD,Macapinlac HA,Podoloff DA

更新日期：2009-10-01 00:00:00