Artificial intelligence, machine (deep) learning and radio(geno)mics: definitions and nuclear medicine imaging applications.

abstract：PURPOSE:Iterative reconstruction methods based on ordered-subset expectation maximisation (OSEM) has replaced filtered backprojection (FBP) in many clinical settings owing to the superior image quality. Whether OSEM is as accurate as FBP in quantitative positron emission tomography (PET) is uncertain. We compared the a...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Søndergaard HM,Madsen MM,Boisen K,Bøttcher M,Schmitz O,Nielsen TT,Bøtker HE,Hansen SB

更新日期：2007-03-01 00:00:00

abstract：INTRODUCTION:Vascular prosthesis infection (VPI) is a life-threatening complication that occurs in 0.5-5% of prostheses. Low-grade infections in non-acute patients are a diagnostic challenge requiring a new method with good diagnostic accuracy. The aim of this work was to define the accuracy of (18)F-FDG PET/CT in thes...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Spacek M,Belohlavek O,Votrubova J,Sebesta P,Stadler P

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:Hypometabolism of the posterior cingulate cortex (PCC) in early Alzheimer's disease (AD) is thought to arise in part due to AD-specific neuronal damage to the hippocampal formation. Here, we explored the association between microstructural alterations within the hippocampus and whole-brain glucose metabolism in...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Yakushev I,Schreckenberger M,Müller MJ,Schermuly I,Cumming P,Stoeter P,Gerhard A,Fellgiebel A

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:To determine if preoperative [(18)F]FDG-PET/CT imaging has prognostic significance in patients with uterine cervical cancer. METHODS:Patients with FIGO stage IB to IIA cervical cancer were imaged with integrated FDG PET/CT before radical surgery. The relationship between the maximum standardized uptake value (...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Chung HH,Nam BH,Kim JW,Kang KW,Park NH,Song YS,Chung JK,Kang SB

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:To determine the value of (68)Ga-DOTA-TOC and (18)F-FDG PET/CT for initial and follow-up evaluation of patients with neuroendocrine tumour (NET) treated with peptide receptor radionuclide therapy (PRRT). METHODS:We evaluated 66 patients who had histologically proven NET and underwent both PRRT and three combin...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nilica B,Waitz D,Stevanovic V,Uprimny C,Kendler D,Buxbaum S,Warwitz B,Gerardo L,Henninger B,Virgolini I,Rodrigues M

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To examine the diagnostic performance of (18)F-fluorothymidine (FLT) PET/CT in primary and metastatic lymph node colorectal cancer foci in comparison with (18)F-fluorodeoxyglucose (FDG) PET/CT. METHODS:The study population comprised 28 patients with 30 newly diagnosed colorectal cancers who underwent surgical ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nakajo M,Nakajo M,Kajiya Y,Jinguji M,Nishimata N,Shimaoka S,Nihara T,Aridome K,Tanaka S,Fukukura Y,Tani A,Koriyama C

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:Neuroendocrine diseases are a heterogeneous group of entities with the ability to take up amine precursors, such as L-DOPA, and convert them into biogenic amines, such as dopamine. Congenital hyperinsulinism of infancy (HI) is a neuroendocrine disease secondary to either focal adenomatous hyperplasia or a diffu...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ribeiro MJ,Boddaert N,Bellanné-Chantelot C,Bourgeois S,Valayannopoulos V,Delzescaux T,Jaubert F,Nihoul-Fékété C,Brunelle F,De Lonlay P

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:An image-based scatter correction (IBSC) method was developed to convert scatter-uncorrected into scatter-corrected SPECT images. The purpose of this study was to validate this method by means of phantom simulations and human studies with 99mTc-labeled tracers, based on comparison with the conventional triple e...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Shidahara M,Watabe H,Kim KM,Kato T,Kawatsu S,Kato R,Yoshimura K,Iida H,Ito K

更新日期：2005-10-01 00:00:00

abstract：PURPOSE:As hypoxia is believed to play an important role in the development and progression of prostate cancer, we evaluated whether 18F-labeled fluoroazomycin arabinoside (18F-FAZA) would be useful to identify tumor hypoxia in resectable prostate cancer. METHODS:Positron emission tomography (PET)/CT was performed on ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Garcia-Parra R,Wood D,Shah RB,Siddiqui J,Hussain H,Park H,Desmond T,Meyer C,Piert M

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:Positron emission tomography (PET) has been widely utilized in the study of traumatic brain injury (TBI) for decades. While most applications of PET have attempted to assess neuronal function after TBI, more recently, novel radiotracers have sought to image biomarkers in the context of TBI and chronic traumatic...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ayubcha C,Revheim ME,Newberg A,Moghbel M,Rojulpote C,Werner TJ,Alavi A

更新日期：2021-02-01 00:00:00

abstract：PURPOSE:Increasing evidence supports the value of peptide receptor radionuclide therapy (PRRT) in patients with metastatic neuroendocrine tumours (NET), but there are limited data on its specific efficacy in NET of small intestinal (midgut) origin. This study aims to define the benefit of PRRT with (177)Lu-octreotate f...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sabet A,Dautzenberg K,Haslerud T,Aouf A,Sabet A,Simon B,Mayer K,Biersack HJ,Ezziddin S

更新日期：2015-07-01 00:00:00

abstract：PURPOSE:Medial temporal impairment can be detected clinically and by morphological imaging during Alzheimer's disease (AD), but the existence of a functional impairment in this area seems to be less well established. Yet such functional impairment is classically found in other degenerative cortical dementias, such as t...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Basely M,Ceccaldi M,Boyer L,Mundler O,Guedj E

更新日期：2013-06-01 00:00:00

abstract：:We assessed the accuracy of brain perfusion single-photon emission computed tomography (SPECT) in discriminating between patients with probable Alzheimer's disease (AD) at the very early stage and age-matched controls before and after partial volume correction (PVC). Three-dimensional MRI was used for PVC. We randomly...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kanetaka H,Matsuda H,Asada T,Ohnishi T,Yamashita F,Imabayashi E,Tanaka F,Nakano S,Takasaki M

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:In children with Hodgkin's disease and non-Hodgkin's lymphoma, the ability of (18)F-fluoro-2-deoxy-D-glucose PET/CT and conventional imaging (CI) to detect malignant lesions and predict poor lesion response to therapy was assessed and compared. METHODS:A retrospective review of findings reported on PET/CT and ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： London K,Cross S,Onikul E,Dalla-Pozza L,Howman-Giles R

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:(18)F-Fluoride PET/CT is a relatively undervalued diagnostic test to measure bone metabolism in bone diseases. Hyperostosis cranialis interna (HCI) is a (hereditary) bone disease characterised by endosteal hyperostosis and osteosclerosis of the skull and the skull base. Bone overgrowth causes entrapment and dys...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Waterval JJ,Van Dongen TM,Stokroos RJ,Teule JG,Kemerink GJ,Brans B,Nieman FH,Manni JJ

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:Multidrug resistance (MDR) impedes cancer treatment. Two efflux transporters from the ATP-binding cassette (ABC) family, ABCB1 and ABCG2, may contribute to MDR by restricting the entry of therapeutic drugs into tumor cells. Although a higher expression of these transporters has been correlated with an unfavorab...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kannan P,Füredi A,Dizdarevic S,Wanek T,Mairinger S,Collins J,Falls T,van Dam RM,Maheshwari D,Lee JT,Szakács G,Langer O

更新日期：2020-07-01 00:00:00

abstract：:Functional imaging of small animals, such as mice and rats, using ultra-high resolution positron emission tomography (PET) and single-photon emission tomography (SPET), is becoming a valuable tool for studying animal models of human disease. While several studies have shown the utility of PET imaging in small animals,...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Acton PD,Choi SR,Plössl K,Kung HF

更新日期：2002-05-01 00:00:00

abstract：PURPOSE:The J-ACCESS [Japanese investigation of prognosis based on gated single photon emission computed tomography (SPECT)] study found that quantitative gated myocardial SPECT (QGS) is valuable for predicting the prognosis of Japanese patients with known or suspected ischaemic heart disease. The present study evaluat...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Momose M,Nakajima K,Nishimura T

更新日期：2009-08-01 00:00:00

abstract：PURPOSE:Our purpose was to examine the prognostic value of post-CRT PET based on the presence or absence of FDG-avid metastatic lymph node(s) and metabolic response of the primary tumor in patients with clinically node-positive ESCC treated with definitive chemoradiotherapy (dCRT). METHODS:We identified 108 eligible p...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Yap WK,Chang YC,Hsieh CH,Chao YK,Chen CC,Shih MC,Hung TM

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:The aim of this prospective study is to evaluate the combined use of fluorine-18 fluorodeoxyglucose ((18) F-FDG) and fluorine-18 sodium fluoride ((18) F-NaF) PET/CT in the skeletal assessment of patients with multiple myeloma (MM) and to compare the efficacy of these two PET tracers regarding detection of mye...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sachpekidis C,Goldschmidt H,Hose D,Pan L,Cheng C,Kopka K,Haberkorn U,Dimitrakopoulou-Strauss A

更新日期：2014-07-01 00:00:00

abstract：PURPOSE:Sympathetic nervous system (SNS) hyperactivity is a salient characteristic of chronic heart failure (HF) and contributes to the progression of the disease. Iodine-123 meta-iodobenzylguanidine (123I-mIBG) imaging has been successfully used to assess cardiac SNS activity in HF patients and to predict prognosis. I...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Rengo G,Pagano G,Vitale DF,Formisano R,Komici K,Petraglia L,Parisi V,Femminella GD,de Lucia C,Paolillo S,Cannavo A,Attena E,Pellegrino T,Dellegrottaglie S,Memmi A,Trimarco B,Cuocolo A,Filardi PP,Leosco D,Ferrara N

更新日期：2016-12-01 00:00:00

abstract：INTRODUCTION:Positron emission tomography (PET) is a fully quantitative technology for imaging metabolic pathways and dynamic processes in vivo. Attenuation correction of raw PET data is a prerequisite for quantification and is typically based on separate transmission measurements. In PET/CT attenuation correction, how...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hofmann M,Pichler B,Schölkopf B,Beyer T

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:Age-related values of (123)I-orthoiodohippurate (OIH) single kidney clearance rate (Cl) were estimated in a large cohort of likely normal children aged between 0 and 18 years. METHODS:Among 4,111 children examined in the past 10 years, 917 were selected with the following inclusion criteria: (a) mild ultrasono...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Imperiale A,Olianti C,Comis G,La Cava G

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:To explore the potential complementary value of PET/CT and dynamic contrast-enhanced MRI in predicting pathological response to neoadjuvant chemotherapy (NAC) of breast cancer and the dependency on breast cancer subtype. METHODS:We performed (18)F-FDG PET/CT and MRI examinations before and during NAC. The imag...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Pengel KE,Koolen BB,Loo CE,Vogel WV,Wesseling J,Lips EH,Rutgers EJ,Valdés Olmos RA,Vrancken Peeters MJ,Rodenhuis S,Gilhuijs KG

更新日期：2014-08-01 00:00:00

abstract：:Medical imaging has made a major contribution to cerebral dysfunction due to inherited diseases, as well as injuries sustained with modern living, such as car accidents, falling down, and work-related injuries. These injuries, up until the introduction of sensitive techniques such as positron emission tomography (PET)...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hayempour BJ,Alavi A

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:Functional brain (99m)Tc-HMPAO single-photon emission computed tomography (SPECT) is a useful diagnostic tool for assessment of regional cerebral blood flow, particularly in dementia, cerebrovascular disease and epilepsy. Currently, the European and American Association of Nuclear Medicine Procedure Guidelines ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Thomsen G,de Nijs R,Hogh-Rasmussen E,Frokjaer V,Svarer C,Knudsen GM

更新日期：2008-12-01 00:00:00

abstract：INTRODUCTION:The quantitative imaging features (radiomics) that can be obtained from the different modalities of current-generation hybrid imaging can give complementary information with regard to the tumour environment, as they measure different morphologic and functional imaging properties. These multi-parametric ima...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Castiglioni I,Gallivanone F,Soda P,Avanzo M,Stancanello J,Aiello M,Interlenghi M,Salvatore M

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:The aim of this study was to assess the accuracy of (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT to visualize lymph node metastases before the start of neoadjuvant chemotherapy and to determine how often the visualization is sufficiently prominent to allow monitoring of the axillary resp...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Straver ME,Aukema TS,Olmos RA,Rutgers EJ,Gilhuijs KG,Schot ME,Vogel WV,Peeters MJ

更新日期：2010-06-01 00:00:00

abstract：:Paragangliomas or glomus tumours of the head and neck region are rare somatostatin receptor-expressing neuroendocrine tumours. Precise preoperative diagnosis is of special importance in order to adequately weigh the potential benefit of the operation against the inherent risks of the procedure. In this study, the clin...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Schmidt M,Fischer E,Dietlein M,Michel O,Weber K,Moka D,Stennert E,Schicha H

更新日期：2002-12-01 00:00:00

abstract：PURPOSE:Here, the expression of F4/80 on the cell surface of murine macrophages was exploited to develop a novel imaging tracer that could visualize macrophages in vivo. METHODS:The immunoreactive fraction and IC50 of anti-F4/80-A3-1, conjugated with diethylenetriaminepentaacetic acid (DTPA) and radiolabelled with (11...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Terry SY,Boerman OC,Gerrits D,Franssen GM,Metselaar JM,Lehmann S,Oyen WJ,Gerdes CA,Abiraj K

更新日期：2015-08-01 00:00:00