Direct comparison of (68)Ga-DOTA-TOC and (18)F-FDG PET/CT in the follow-up of patients with neuroendocrine tumour treated with the first full peptide receptor radionuclide therapy cycle.

abstract：:The development of monofunctional DTPA derivatives has been a major breakthrough in the labelling of proteins or peptides with a variety of radiometals. Although this methodology is simple and useful for indium-111 labelling, the stability of these conjugates is too low for most therapeutic nuclides. Cyclic chelators,...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Béhé M,Becker W,Gotthardt M,Angerstein C,Behr TM

更新日期：2003-08-01 00:00:00

abstract：PURPOSE:In vivo Alzheimer's disease (AD) biomarkers for tau pathology are cerebrospinal fluid (CSF) phosphorylated tau (p-tau) and [18F]flortaucipir positron emission tomography (PET). Our aim was to assess associations between CSF p-tau with [18F]flortaucipir PET and the associations of both tau biomarkers with cognit...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Wolters EE,Ossenkoppele R,Verfaillie SCJ,Coomans EM,Timmers T,Visser D,Tuncel H,Golla SSV,Windhorst AD,Boellaard R,van der Flier WM,Teunissen CE,Scheltens P,van Berckel BNM

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:This study investigated the diagnostic performance and prognostic value of fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT in suspected malignant pleural mesothelioma (MPM) recurrence, in the context of patterns and intensity of FDG uptake, histologic type, and treatment algorithm. METHODS:Fifty...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Gerbaudo VH,Mamede M,Trotman-Dickenson B,Hatabu H,Sugarbaker DJ

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:This study proposes an automated prostate cancer (PC) lesion characterization method based on the deep neural network to determine tumor burden on 68Ga-PSMA-11 PET/CT to potentially facilitate the optimization of PSMA-directed radionuclide therapy. METHODS:We collected 68Ga-PSMA-11 PET/CT images from 193 patie...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Zhao Y,Gafita A,Vollnberg B,Tetteh G,Haupt F,Afshar-Oromieh A,Menze B,Eiber M,Rominger A,Shi K

更新日期：2020-03-01 00:00:00

abstract：INTRODUCTION:The precise clinical utility of lung 201Tl uptake in exercise SPECT myocardial perfusion imaging remains open to research. This study validates an optimal index for lung 201Tl uptake measurement and assesses its value in the prediction of higher-risk coronary artery disease (CAD). METHOD:Three hundred and...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Moralidis E,Spyridonidis T,Arsos G,Anagnostopoulos C

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:The aim of this feasibility study was to use slice selective learning using a Generative Adversarial Network for external validation. We aimed to build a model less sensitive to PET imaging acquisition environment, since differences in environments negatively influence network performance. To investigate the sl...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kim HW,Lee HE,Lee S,Oh KT,Yun M,Yoo SK

更新日期：2020-08-01 00:00:00

abstract：:We present a system of image co-registration and its validation in phantom and volunteer studies. The system co-registered images via six novel non-invasive and non-radioactive external markers. The fiducial markers were attached with sponge bases on the skin surface of the phantom and the volunteers in a non-collinea...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Wu TH,Wang JK,Lee JJ,Liu RS,Guo WY

更新日期：2003-06-01 00:00:00

abstract：INTRODUCTION:Somatostatin receptor imaging with PET is the standard of care for patients with a neuroendocrine tumour (NET). Since therapy and imaging with somatostatin analogues utilize the same receptor, current guidelines recommend withdrawing long-acting somatostatin analogues for 3-4 weeks prior to somatostatin re...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Aalbersberg EA,de Wit-van der Veen BJ,Versleijen MWJ,Saveur LJ,Valk GD,Tesselaar MET,Stokkel MPM

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:Various strategies have been applied to increase the engraftment of an intramyocardial cell transplant (Tx) to treat ischemic myocardium. Thereby, co-transplanted fibroblasts (FB) improve the long-term survival of stem cell derivatives (SCD) in a murine model of myocardial infarction. For therapeutic use, the t...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Lang C,Lehner S,Todica A,Boening G,Zacherl M,Franz WM,Krause BJ,Bartenstein P,Hacker M,David R

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:The aim of this study is to report on a collective of 20 children from Belarus who had developed papillary thyroid carcinoma with pulmonary metastases after the Chernobyl disaster. In all children fractionated radioiodine therapy (RIT) was ceased before achieving complete remission due to a lack of further effe...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Biko J,Reiners C,Kreissl MC,Verburg FA,Demidchik Y,Drozd V

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:The molecular imaging of tumour neoangiogenesis currently represents a major field of research for the diagnostic and treatment strategy of solid tumours. Endothelial cells from tumour neovessels overexpress the alpha(v)beta(3) integrin, which selectively binds to Arg-Gly-Asp (RGD)-containing peptides. We evalu...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sancey L,Ardisson V,Riou LM,Ahmadi M,Marti-Batlle D,Boturyn D,Dumy P,Fagret D,Ghezzi C,Vuillez JP

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:Although [(18)F]FDG PET can measure therapy response sooner and more accurately than morphological imaging techniques, there is still some debate as to whether [(18)F]FDG uptake really reflects changes in the viable cell fraction. In this study changes in [(18)F]FDG uptake were investigated in a lymphoma model ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Brepoels L,De Saint-Hubert M,Stroobants S,Verhoef G,Balzarini J,Mortelmans L,Mottaghy FM

更新日期：2010-08-01 00:00:00

abstract：:Cardiovascular diseases are the leading cause of death not only in Europe but also in the rest of the World. Preventive measures, however, often fail and cardiovascular disease may manifest as an acute coronary syndrome, stroke or even sudden death after years of silent progression. Thus, there is a considerable need ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bucerius J,Hyafil F,Verberne HJ,Slart RH,Lindner O,Sciagra R,Agostini D,Übleis C,Gimelli A,Hacker M,Cardiovascular Committee of the European Association of Nuclear Medicine (EANM).

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:To evaluate the role of F-18-Fluorothymidine (FLT) PET/CT in lymphoma patients with suspected recurrent or residual disease. METHODS:Adult lymphoma patients presenting with positive or equivocal F-18-FDG PET/CT at end-treatment or follow-up were prospectively addressed to an additional F-18-FLT-PET/CT. SUV max...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Zanoni L,Broccoli A,Lambertini A,Pellegrini C,Stefoni V,Lodi F,Fonti C,Nanni C,Zinzani PL,Fanti S

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:4-[(18)F]-ADAM is a potent serotonin transport imaging agent. We studied its toxicity in rats and radiation dosimetry in monkeys before human studies are undertaken. METHODS:Single and multiple-dosage toxicity studies were conducted in Sprague-Dawley rats. Male and female rats were injected intravenously with ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Huang YY,Ma KH,Tseng TW,Chou TK,Ng H,Mirsalis JC,Fu YK,Chu TC,Huang WS,Shiue CY

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:Radioembolization (RE) is a promising treatment option for biliary tract cancers (BTC). We report here the largest series to date using this treatment modality. METHODS:We retrospectively studied data from 64 patients treated outside prospective clinical trial at our institution. We studied baseline characteri...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bourien H,Palard X,Rolland Y,Le Du F,Beuzit L,Uguen T,Le Sourd S,Pracht M,Manceau V,Lièvre A,Boudjema K,Garin E,Edeline J

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:Physiological glucose uptake by the myocardium may hamper visualization of coronary atherosclerotic plaques in (18)F-FDG PET studies. Intracellular myocardial calcium relates to glucose influx. We assessed whether administration of a calcium channel blocker such as verapamil could decrease myocardial (18)F-FDG ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Gaeta C,Fernández Y,Pavía J,Flotats A,Artigas C,Deportos J,Geraldo L,Carrió I

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:Epicardial adipose tissue (EAT) has been linked to coronary artery disease (CAD) and coronary microvascular dysfunction. However, its injurious effect may also impact the underlying myocardium. This study aimed to determine the impact of obesity on the quantitative relationship between left ventricular mass (LV...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bakkum MJ,Danad I,Romijn MA,Stuijfzand WJ,Leonora RM,Tulevski II,Somsen GA,Lammertsma AA,van Kuijk C,van Rossum AC,Raijmakers PG,Knaapen P

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:Medial temporal impairment can be detected clinically and by morphological imaging during Alzheimer's disease (AD), but the existence of a functional impairment in this area seems to be less well established. Yet such functional impairment is classically found in other degenerative cortical dementias, such as t...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Basely M,Ceccaldi M,Boyer L,Mundler O,Guedj E

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:To test the performance of sequential 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in predicting survival after sunitinib therapies in patients with cancer of unknown primary (CUP). METHODS:CUP patients were enrolled for sequential PET/CT scanning for sunitinib and a con...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ma Y,Xu W,Bai R,Li Y,Yu H,Yang C,Shi H,Zhang J,Li J,Wang C,Xiao J

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:We assessed the effects of the COVID-19 pandemic on myocardial perfusion imaging (MPI) for ischemic heart disease during the lockdown imposed by the Italian Government. METHODS:We retrospectively reviewed the number and the findings of stress single-photon emission computed tomography (SPECT)-MPI performed bet...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nappi C,Megna R,Acampa W,Assante R,Zampella E,Gaudieri V,Mannarino T,Green R,Cantoni V,Petretta M,Cuocolo A

更新日期：2021-02-01 00:00:00

abstract：:This study investigated the feasibility of ordered subsets expectation maximisation (OS-EM) reconstruction of 180 degrees pinhole single-photon emission tomography (SPET) acquired in body contour mode (variable distance between the detector and the axis of rotation for each projection) with or without a tilted detecto...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Seret A,Flérès D,Firket O,Defrise M

更新日期：2003-09-01 00:00:00

abstract：PURPOSE:For the assessment of folate-based radiopharmaceuticals, human nasopharyngeal KB carcinoma cells are traditionally used although nasopharyngeal cancer is rare. On the other hand, the folate receptor (FR) is frequently overexpressed on diverse cancer types, the highest frequency (>90%) being on ovarian carcinoma...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Müller C,Schubiger PA,Schibli R

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:The aim of the study was to assess the role of CA 15.3, CT and positron emission tomography (PET)/CT in patients with breast cancer and suspected disease relapse after primary treatment. METHODS:We studied 111 consecutive patients (mean age 61 ± 12 years) with previous breast cancer, already treated and with c...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Evangelista L,Baretta Z,Vinante L,Cervino AR,Gregianin M,Ghiotto C,Saladini G,Sotti G

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:This investigation aimed to identify significant predictors of regional sympathetic denervation quantified by 11C-hydroxyephedrine (HED) positron emission tomography (PET) in patients with heart failure with preserved left ventricular ejection fraction (HFpEF). METHODS:Included in the study were 34 patients (a...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Aikawa T,Naya M,Obara M,Oyama-Manabe N,Manabe O,Magota K,Ito YM,Katoh C,Tamaki N

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:[(18)F]Fluciclovine (anti-[(18)F]FACBC) is a synthetic amino acid developed for PET assessment of the anabolic component of tumour metabolism in clinical routine. This phase 1 trial evaluated the safety, tracer stability and uptake kinetics of [(18)F]fluciclovine in patients. METHODS:Six patients with biopsy-p...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sörensen J,Owenius R,Lax M,Johansson S

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:We developed and tested a single acquisition rest (99m)Tc-sestamibi/stress (201)Tl dual isotope protocol (SDI) with the intention of improving the clinical workflow and patient comfort of myocardial perfusion single photon emission computed tomography (SPECT). METHODS:The technical feasibility of SDI was evalu...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Dey T,Backus BE,Romijn RL,Wieczorek H,Verzijlbergen JF

更新日期：2014-03-01 00:00:00

abstract：PURPOSE:PET is a powerful tool for assessing targeted therapy. Since (18)F-FDG shows a potential prognostic value in medullary thyroid carcinoma (MTC), this study evaluated (18)F-FDG PET alone and combined with morphological and biomarker evaluations as a surrogate marker of overall survival (OS) in patients with progr...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Salaun PY,Campion L,Ansquer C,Frampas E,Mathieu C,Robin P,Bournaud C,Vuillez JP,Taieb D,Rousseau C,Drui D,Mirallié E,Borson-Chazot F,Goldenberg DM,Chatal JF,Barbet J,Kraeber-Bodéré F

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:In single-photon emission computed tomography (SPECT) of the dopaminergic system, measurements of striatal uptake are useful for diagnosis and patient follow-up but are strongly biased by the partial volume effect (PVE). We studied whether PVE correction might improve patient classification based on binding pot...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Soret M,Koulibaly PM,Darcourt J,Buvat I

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:The aim of this study was to compare the accuracy of (123)I-MIBG SPECT/CT with that of (68)Ga-DOTATOC PET/CT for staging extraadrenal paragangliomas (PGL) using both functional and anatomical images (i.e. combined cross-sectional imaging) as the reference standards. METHODS:The study included three men and sev...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kroiss A,Shulkin BL,Uprimny C,Frech A,Gasser RW,Url C,Gautsch K,Madleitner R,Nilica B,Sprinzl GM,Gastl G,Fraedrich G,Virgolini IJ

更新日期：2015-01-01 00:00:00