Electrocardiographic-gated dual-isotope simultaneous acquisition SPECT using 18F-FDG and 99mTc-sestamibi to assess myocardial viability and function in a single study.

abstract：PURPOSE:We developed and tested a single acquisition rest (99m)Tc-sestamibi/stress (201)Tl dual isotope protocol (SDI) with the intention of improving the clinical workflow and patient comfort of myocardial perfusion single photon emission computed tomography (SPECT). METHODS:The technical feasibility of SDI was evalu...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Dey T,Backus BE,Romijn RL,Wieczorek H,Verzijlbergen JF

更新日期：2014-03-01 00:00:00

abstract：PURPOSE:We previously reported in a small series of patients that (99m)Tc-3,3-diphosphono-1,2-propanodicarboxylic acid ((99m)Tc-DPD) scintigraphy tested positive in transthyretin-related (TTR) (both mutant and wild-type) but not in primary (AL) amyloidotic cardiomyopathy (AC). We extended our study to a larger cohort o...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Rapezzi C,Quarta CC,Guidalotti PL,Longhi S,Pettinato C,Leone O,Ferlini A,Salvi F,Gallo P,Gagliardi C,Branzi A

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:In Churg-Strauss syndrome (CSS) it is important to detect cardiac involvement, which predicts poor prognosis. This study evaluated whether (123)I-metaiodobenzylguanidine (MIBG) scintigraphy could detect cardiac damage and predict cardiac events in CSS. METHODS:(123)I-MIBG scintigraphy was performed in 28 patie...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Horiguchi Y,Morita Y,Tsurikisawa N,Akiyama K

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:The molecular imaging of tumour neoangiogenesis currently represents a major field of research for the diagnostic and treatment strategy of solid tumours. Endothelial cells from tumour neovessels overexpress the alpha(v)beta(3) integrin, which selectively binds to Arg-Gly-Asp (RGD)-containing peptides. We evalu...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sancey L,Ardisson V,Riou LM,Ahmadi M,Marti-Batlle D,Boturyn D,Dumy P,Fagret D,Ghezzi C,Vuillez JP

更新日期：2007-12-01 00:00:00

abstract：:We assessed the accuracy of brain perfusion single-photon emission computed tomography (SPECT) in discriminating between patients with probable Alzheimer's disease (AD) at the very early stage and age-matched controls before and after partial volume correction (PVC). Three-dimensional MRI was used for PVC. We randomly...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kanetaka H,Matsuda H,Asada T,Ohnishi T,Yamashita F,Imabayashi E,Tanaka F,Nakano S,Takasaki M

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:According to the updated WHO classification of gliomas with its emphasis on molecular parameters, tumours with an IDH-wildtype status have a dismal prognosis. To ensure timely adjustment of treatment, demand for non-invasive prediction methods is high. 18F-FET PET has been shown to be an important diagnostic to...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Vettermann F,Suchorska B,Unterrainer M,Nelwan D,Forbrig R,Ruf V,Wenter V,Kreth FW,Herms J,Bartenstein P,Tonn JC,Albert NL

更新日期：2019-11-01 00:00:00

abstract：:The introduction of multislice computed tomography (MSCT) has allowed non-invasive coronary angiography. Although widely applied, extensive information on technical details of the technique is lacking. This survey offers detailed information on patient preparation, data acquisition, reconstruction and interpretation. ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Cademartiri F,Schuijf JD,Mollet NR,Malagutti P,Runza G,Bax JJ,de Feyter PJ

更新日期：2005-11-01 00:00:00

abstract：PURPOSE:The purpose of our study was 1) to evaluate the diagnostic performance of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT), 2) to assess the impact of FDG PET/CT on treatment decision-making, and 3) to estimate the prognostic value of FDG PET/CT in the restaging process a...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Alongi P,Picchio M,Zattoni F,Spallino M,Gianolli L,Saladini G,Evangelista L

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:The Alzheimer's disease (AD) pathology is characterized by fibrillar amyloid deposits and neurofibrillary tangles, as well as the activation of astrocytosis, microglia activation, atrophy, dysfunctional synapse, and cognitive impairments. The aim of this study was to test the hypothesis that astrocytosis is cor...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Choo IL,Carter SF,Schöll ML,Nordberg A

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:Although [(18)F]FDG PET can measure therapy response sooner and more accurately than morphological imaging techniques, there is still some debate as to whether [(18)F]FDG uptake really reflects changes in the viable cell fraction. In this study changes in [(18)F]FDG uptake were investigated in a lymphoma model ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Brepoels L,De Saint-Hubert M,Stroobants S,Verhoef G,Balzarini J,Mortelmans L,Mottaghy FM

更新日期：2010-08-01 00:00:00

abstract：INTRODUCTION:Fluorescence guidance is an upcoming methodology to improve surgical accuracy. Challenging herein is the identification of the minimum dose at which the tracer can be detected with a clinical-grade fluorescence camera. Using a hybrid tracer such as indocyanine green (ICG)-(99m)Tc-nanocolloid, it has become...

journal_title：European journal of nuclear medicine and molecular imaging

authors： KleinJan GH,Bunschoten A,van den Berg NS,Olmos RA,Klop WM,Horenblas S,van der Poel HG,Wester HJ,van Leeuwen FW

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:To evaluate the sensitivity and specificity of PET/CT findings in PMR and generate a diagnostic algorithm utilizing a minimum number of musculoskeletal sites. METHODS:Steroid-naïve patients with newly diagnosed PMR (2012 EULAR/ACR classification criteria) were prospectively recruited to undergo whole-body 18F-...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Owen CE,Poon AMT,Yang V,McMaster C,Lee ST,Liew DFL,Leung JL,Scott AM,Buchanan RRC

更新日期：2020-09-01 00:00:00

abstract：:The evaluation of myocardial glucose utilisation with fluorine-18 fluorodeoxyglucose (FDG) and positron emission tomography is currently considered the most reliable tool for the identification of myocardial viability. However, the investigations using FDG imaging to predict improvement in left ventricular (LV) functi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Knuuti J,Schelbert HR,Bax JJ

更新日期：2002-09-01 00:00:00

abstract：PURPOSE:Radionuclide renography with angiotensin converting enzyme (ACE) inhibition plays an important role in the diagnosis of haemodynamically significant renal artery stenosis. Angiotensin receptor antagonists inhibit the renin angiotensin system at different levels from ACE inhibitors by selectively blocking the bi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Günay EC,Oztürk MH,Ergün EL,Altun B,Salanci BV,Uğur O,Cil B,Hekimoğlu B,Caner B

更新日期：2005-09-01 00:00:00

abstract：PURPOSE:The emergence of the novel SARS-CoV-2 pathogen and lethal COVID-19 disease pandemic poses major diagnostic challenges. The study aims to describe the spectrum and prevalence of thoracic and extrathoracic incidental findings in patients who have undergone 18F-FDG PET/CT during the first 3 weeks of the COVID-19 U...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Halsey R,Priftakis D,Mackenzie S,Wan S,Davis LM,Lilburn D,Thornton A,Papathanasiou N,Gnanasegaran G,Bomanji J

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate the impact of [18F]fluorodeoxy-D-glucose positron emission tomography (FDG-PET) on the primary staging of patients with small-cell lung cancer (SCLC). METHODS:FDG-PET was performed in 120 consecutive patients with SCLC during primary staging. In addition, brain examina...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Brink I,Schumacher T,Mix M,Ruhland S,Stoelben E,Digel W,Henke M,Ghanem N,Moser E,Nitzsche EU

更新日期：2004-12-01 00:00:00

abstract：PURPOSE:We report the biodistribution and radiation dosimetry of an integrin αvβ3 specific PET tracer (18)F-AlF-NOTA-E[PEG4-c(RGDfk)]2) (denoted as (18)F-Alfatide II). We also assessed the value of (18)F-Alfatide II in patients with brain metastases. METHODS:A series of torso (from the skull to the thigh) static image...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Yu C,Pan D,Mi B,Xu Y,Lang L,Niu G,Yang M,Wan W,Chen X

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:Despite recent advances in lumbar spine stabilization surgery (LSSS), a high number of patients continue to complain of persistent/recurrent lumbar pain after LSSS. Conventional imaging (plain radiography, CT and MRI) is commonly performed to assess potential lumbar pain generators, but findings are equivocal i...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Al-Riyami K,Vöö S,Gnanasegaran G,Pressney I,Meir A,Casey A,Molloy S,Allibone J,Bomanji J

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:(153)Sm-ethylenediaminetetramethylenephosphonic acid (EDTMP; Quadramet) is indicated for the treatment of painful bone metastases, whereas zoledronic acid (Zometa) is indicated for the prevention of skeletal complications. Because of the different therapeutic effects, combining the treatments may be beneficial....

journal_title：European journal of nuclear medicine and molecular imaging

authors： Lam MG,Dahmane A,Stevens WH,van Rijk PP,de Klerk JM,Zonnenberg BA

更新日期：2008-04-01 00:00:00

abstract：PURPOSE:Radioguided sentinel lymph node biopsy (SLNB) is the standard of care in breast cancer and melanoma. Additional preoperative Single-photon emission computed tomography (SPECT/CT) for improved anatomical co-registration of the SLNs causes additional radiation exposure and is time-consuming and expensive. The aim...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bluemel C,Safak G,Cramer A,Wöckel A,Gesierich A,Hartmann E,Schmid JS,Kaiser F,Buck AK,Herrmann K

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:The aim of this prospective study is to evaluate the combined use of fluorine-18 fluorodeoxyglucose ((18) F-FDG) and fluorine-18 sodium fluoride ((18) F-NaF) PET/CT in the skeletal assessment of patients with multiple myeloma (MM) and to compare the efficacy of these two PET tracers regarding detection of mye...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sachpekidis C,Goldschmidt H,Hose D,Pan L,Cheng C,Kopka K,Haberkorn U,Dimitrakopoulou-Strauss A

更新日期：2014-07-01 00:00:00

abstract：INTRODUCTION:This study aims to reveal the feasibility and potential of molecular connectivity based on neurotransmission in comparison with the metabolic connectivity with an application to dopaminergic pathways. For this purpose, we propose to compare the neurotransmission connectivity findings using 123I-FP-CIT SPEC...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Verger A,Horowitz T,Chawki MB,Eusebio A,Bordonne M,Azulay JP,Girard N,Guedj E

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:This study aimed to establish an effective nomogram to predict primary distant metastasis (DM) in patients with nasopharyngeal carcinoma (NPC) to guide the application of PET/CT. METHODS:In total, 3591 patients with pathologically confirmed NPC were consecutively enrolled. The nomogram was constructed based on...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Xiao BB,Lin DF,Sun XS,Zhang X,Guo SS,Liu LT,Luo DH,Sun R,Wen YF,Li JB,Lv XF,Han LJ,Yuan L,Liu SL,Tang QN,Liang YJ,Li XY,Guo L,Chen QY,Fan W,Mai HQ,Tang LQ

更新日期：2021-01-08 00:00:00

abstract：PURPOSE:Functional activation protocols are widely applied for the study of brain-cognition relations. Only few take advantage of the intrinsic characteristics of SPECT, particularly those allowing cognitive assessment outside of the camera, in settings close to the standard clinical or laboratory ones. The purpose of ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ludwig C,Chicherio C,Terraneo L,Magistretti P,de Ribaupierre A,Slosman D

更新日期：2008-04-01 00:00:00

abstract：PURPOSE:(11)C-methionine (MET) PET is an established diagnostic tool for glioma. Studies have suggested that MET uptake intensity in the tumor is a useful index for predicting patient outcome. Because MET uptake is known to reflect tumor expansion more accurately than MRI, we aimed to elucidate the association between ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kobayashi K,Hirata K,Yamaguchi S,Manabe O,Terasaka S,Kobayashi H,Shiga T,Hattori N,Tanaka S,Kuge Y,Tamaki N

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:123I-labelled mZIENT (2β-carbomethoxy-3β-(3′-((Z)-2-iodoethenyl)phenyl)nortropane) has been developed as a radioligand for the serotonin transporter. The aim of this preliminary study was to assess its whole-body biodistribution in humans and estimate dosimetry. METHODS:Three healthy controls and three patient...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nicol A,Krishnadas R,Champion S,Tamagnan G,Stehouwer JS,Goodman MM,Hadley DM,Pimlott SL

更新日期：2012-05-01 00:00:00

abstract：:We here aim to provide a comprehensive and critical review of the literature concerning the clinical applications of positron emission tomography/computed tomography (PET/CT) with radiolabeled choline in patients with prostate cancer (PCa). We will initially briefly summarize the historical context that brought to the...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Giovacchini G,Giovannini E,Leoncini R,Riondato M,Ciarmiello A

更新日期：2017-09-01 00:00:00

abstract：:We present a system of image co-registration and its validation in phantom and volunteer studies. The system co-registered images via six novel non-invasive and non-radioactive external markers. The fiducial markers were attached with sponge bases on the skin surface of the phantom and the volunteers in a non-collinea...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Wu TH,Wang JK,Lee JJ,Liu RS,Guo WY

更新日期：2003-06-01 00:00:00

abstract：PURPOSE:The nucleoside analog 3'-deoxy-3'-(18)F-fluorothymidine (FLT) has been introduced for imaging cell proliferation with positron emission tomography (PET). We prospectively compared the diagnostic efficacy of FLT PET with that of 2-deoxy-2-(18)F-fluoro-D-glucose (FDG) PET for the preoperative nodal and distant me...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Yamamoto Y,Nishiyama Y,Kimura N,Ishikawa S,Okuda M,Bandoh S,Kanaji N,Asakura M,Ohkawa M

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:Metabotropic glutamate receptor subtype 5 (mGluR5) dysfunction has been implicated in several disorders. [(11)C]ABP688, a positron emission tomography (PET) ligand targeting mGluR5, could be a valuable tool in the development of novel therapeutics for these disorders by establishing in vivo drug occupancy. Due ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： DeLorenzo C,Milak MS,Brennan KG,Kumar JS,Mann JJ,Parsey RV

更新日期：2011-06-01 00:00:00