Clinical features and 123I-FP-CIT SPECT imaging in drug-induced parkinsonism and Parkinson's disease.

abstract：PURPOSE:In the present study, we performed a systematic review of the current literature to assess the incremental value of (131)I single photon emission computed tomography (SPECT)/CT for the management of patients with differentiated thyroid cancer (DTC). METHODS:The search of PubMed/MEDLINE and EMBASE databases to ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Xue YL,Qiu ZL,Song HJ,Luo QY

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:Castration-resistant prostate cancer (CRPC) is the most common cause of death in men. The effectiveness of HDAC inhibitors has been demonstrated by preclinical models, but not in clinical studies, probably due to the ineffectively accumulation of HDACI in prostate cancer cells. The purpose of this work was to e...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Chen Z,Wang X,Yang X,Xu Y,Yang Y,Wang H,Li T,Bai P,Yuan G,Chen H,Yang J,Fiedler SA,Striar R,Bernales DR,Koegel RE,Cao Q,Ran C,Xiang B,Li H,Wang C

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:The objective of this study was to determine the incremental staging information provided by positron emission tomography/computed tomography (PET/CT) and its impact on management plans in patients with untreated stage III-IV head and neck squamous cell carcinoma (HNSCC). METHODS:We prospectively studied, betw...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Cacicedo J,Fernandez I,Del Hoyo O,Dolado A,Gómez-Suarez J,Hortelano E,Sancho A,Pijoan JI,Alvarez J,Espinosa JM,Gaafar A,Bilbao P

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:Patients with high-risk neuroblastoma have an increased risk of recurrence and relapse of disease and a very poor prognosis. 131I-metaiodobenzylguanidine (131I-mIBG) in combination with topotecan as a radiosensitizer can be an effective and relatively well-tolerated agent for the treatment of refractory neurobl...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Genolla J,Rodriguez T,Minguez P,Lopez-Almaraz R,Llorens V,Echebarria A

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:To elucidate the prognostic role of post-therapeutic (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET), we conducted a retrospective cohort study analysing the clinical factors that affect overall survival after non-operative therapy for unresectable hepatocellular carcinoma (HCC). METHOD...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Higashi T,Hatano E,Ikai I,Nishii R,Nakamoto Y,Ishizu K,Suga T,Kawashima H,Togashi K,Seo S,Kitamura K,Takada Y,Uemoto S

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to develop a methodology for the comparison of pathology specimens after prostatectomy (post-S) with PET images obtained before surgery (pre-S). This method was used to evaluate the merit of (11)C-choline PET/CT for delineation of gross tumour volume (GTV) in prostate cancer (PC). MET...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Grosu AL,Weirich G,Wendl C,Prokic V,Kirste S,Geinitz H,Souvatzoglou M,Gschwend JE,Schwaiger M,Molls M,Weber WA,Treiber U,Krause BJ

更新日期：2014-12-01 00:00:00

abstract：:[Yttrium-90-DOTA-Tyr(3)]-octreotide (DOTATOC) and [(177)Lu-DOTA-Tyr(3)-Thr(8)]-octreotide (DOTATATE) are used for peptide receptor-mediated radionuclide therapy (PRMRT) in neuroendocrine tumours. No human data comparing these two compounds are available so far. We used (111)In as a surrogate for (90)Y and (177)Lu and ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Forrer F,Uusijärvi H,Waldherr C,Cremonesi M,Bernhardt P,Mueller-Brand J,Maecke HR

更新日期：2004-09-01 00:00:00

abstract：PURPOSE:The purpose of this study was to map treatment-induced (99m)Tc-Hynic-rh-annexin V uptake in normal tissues using co-registration of SPECT and CT. METHODS:Nineteen patients (11 male, 8 female, mean age 57 years) with various malignant tumours (12 lymphomas, four non-small cell lung cancers and three head and ne...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kartachova MS,Valdés Olmos RA,Haas RL,Hoebers FJ,van den Brekel MW,van Zandwijk N,Herk Mv,Verheij M

更新日期：2006-08-01 00:00:00

abstract：RATIONALE:In Parkinson's disease (PD), spatial covariance analysis of 18F-FDG PET data has consistently revealed a characteristic PD-related brain pattern (PDRP). By quantifying PDRP expression on a scan-by-scan basis, this technique allows objective assessment of disease activity in individual subjects. We provide a f...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Meles SK,Renken RJ,Pagani M,Teune LK,Arnaldi D,Morbelli S,Nobili F,van Laar T,Obeso JA,Rodríguez-Oroz MC,Leenders KL

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:Multi-centre trials are an important part of proving the efficacy of procedures, drugs and interventions. Imaging components in such trials are becoming increasingly common; however, without sufficient control measures the usefulness of these data can be compromised. This paper describes a framework for perform...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Dickson JC,Tossici-Bolt L,Sera T,de Nijs R,Booij J,Bagnara MC,Seese A,Koulibaly PM,Akdemir UO,Jonsson C,Koole M,Raith M,Lonsdale MN,George J,Zito F,Tatsch K

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To investigate whether (11)C-N-methylspiperone ((11)C-NMSP) microPET could be used for imaging neural stem cells (NSCs) transplantation in a rat model of traumatic brain injury. METHODS:NSCs were induced to express dopamine receptor type 2 (DRD(2)), then confirmed by RT-PCR, Western blotting and immunocytochem...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Zhang H,Zheng X,Yang X,Fang S,Shen G,Zhao C,Tian M

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:(11)C-PK11195 is a radiopharmaceutical for in vivo assessment of peripheral benzodiazepine receptor (PBR) activity using PET. We sought to clarify the metabolic fate of (11)C-PK11195 in a test-retest setting using radio-HPLC in comparison with radio-TLC, and the whole-body distribution in humans. MATERIALS AND...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Roivainen A,Någren K,Hirvonen J,Oikonen V,Virsu P,Tolvanen T,Rinne JO

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:We previously reported in a small series of patients that (99m)Tc-3,3-diphosphono-1,2-propanodicarboxylic acid ((99m)Tc-DPD) scintigraphy tested positive in transthyretin-related (TTR) (both mutant and wild-type) but not in primary (AL) amyloidotic cardiomyopathy (AC). We extended our study to a larger cohort o...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Rapezzi C,Quarta CC,Guidalotti PL,Longhi S,Pettinato C,Leone O,Ferlini A,Salvi F,Gallo P,Gagliardi C,Branzi A

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:According to the updated WHO classification of gliomas with its emphasis on molecular parameters, tumours with an IDH-wildtype status have a dismal prognosis. To ensure timely adjustment of treatment, demand for non-invasive prediction methods is high. 18F-FET PET has been shown to be an important diagnostic to...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Vettermann F,Suchorska B,Unterrainer M,Nelwan D,Forbrig R,Ruf V,Wenter V,Kreth FW,Herms J,Bartenstein P,Tonn JC,Albert NL

更新日期：2019-11-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the predictive potential of pre-operative regional cerebral blood flow (rCBF) in the pre-supplementary motor area (pre-SMA) and clinical factors in Parkinson's disease (PD) patients treated with subthalamic nucleus (STN) stimulation. METHODS:Ten patients underwent rCBF ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sestini S,Pupi A,Ammannati F,Ramat S,Sorbi S,Sciagrà R,Mansi L,Castagnoli A

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:To investigate clinical implications of FDG uptake in the thyroid glands in patients with advanced breast carcinoma by comparing metabolic and morphologic patterns on positron emission tomography (PET)/computed tomography (CT). METHODS:The institutional review board waived the requirement for informed consent....

journal_title：European journal of nuclear medicine and molecular imaging

authors： Tateishi U,Gamez C,Dawood S,Yeung HW,Cristofanilli M,Inoue T,Macapinlac HA

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:The objective of this article is to present a new method for the diagnosis of insulinoma with the use of [Lys(40)(Ahx-HYNIC-(99m)Tc/EDDA)NH2]-exendin-4. METHODS:Studies were performed in 11 patients with negative results of all available non-isotopic diagnostic methods (8 with symptoms of insulinoma, 2 with ma...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sowa-Staszczak A,Pach D,Mikołajczak R,Mäcke H,Jabrocka-Hybel A,Stefańska A,Tomaszuk M,Janota B,Gilis-Januszewska A,Małecki M,Kamiński G,Kowalska A,Kulig J,Matyja A,Osuch C,Hubalewska-Dydejczyk A

更新日期：2013-04-01 00:00:00

abstract：:Positron emission tomography (PET) has now gained a place in the management of patients with cancer, including those with Hodgkin's disease and non-Hodgkin's lymphoma. Restaging studies and those addressing the monitoring of response to treatment are especially in focus. Most of the knowledge gained has been achieved ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Visvikis D,Ell PJ

更新日期：2003-06-01 00:00:00

abstract：PURPOSE:It has been shown that some primary human tumours and their metastases, including prostate and breast tumours, overexpress gastrin-releasing peptide (GRP) receptors. Bombesin (BN) is a neuropeptide with a high affinity for these GRP receptors. We demonstrated successful scintigraphic visualisation of BN recepto...

journal_title：European journal of nuclear medicine and molecular imaging

authors： de Visser M,Bernard HF,Erion JL,Schmidt MA,Srinivasan A,Waser B,Reubi JC,Krenning EP,de Jong M

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:Radioembolization (RE) is a promising treatment option for biliary tract cancers (BTC). We report here the largest series to date using this treatment modality. METHODS:We retrospectively studied data from 64 patients treated outside prospective clinical trial at our institution. We studied baseline characteri...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bourien H,Palard X,Rolland Y,Le Du F,Beuzit L,Uguen T,Le Sourd S,Pracht M,Manceau V,Lièvre A,Boudjema K,Garin E,Edeline J

更新日期：2019-03-01 00:00:00

abstract：:Multiple myeloma (MM) is characterized by a monoclonal plasma cell population in the bone marrow. Lytic lesions occur in up to 90 % of patients. For many years, whole-body X-ray (WBX) was the method of choice for detecting skeleton abnormalities. However, the value of WBX in relapsing disease is limited because lesion...

journal_title：European journal of nuclear medicine and molecular imaging

authors： de Waal EGM,Glaudemans AWJM,Schröder CP,Vellenga E,Slart RHJA

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:The serotonin-1A (5-HT(1A)) receptor is implicated in the pathophysiology of major neuropsychiatric disorders. Thus, the functional imaging of 5-HT(1A) receptors by positron emission tomography (PET) may contribute to the understanding of its role in those pathologies and their therapeutics. These receptors exi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Lemoine L,Verdurand M,Vacher B,Blanc E,Le Bars D,Newman-Tancredi A,Zimmer L

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:The purpose of this study was to compare dynamic 18F-FGln PET/CT images of healthy subjects and cancer patients and explore the best imaging phase for different cancers. METHODS:Thirteen healthy volunteers and 31 cancer patients separately underwent 18F-FGln and 18F-FDG PET/CT scans within 1 week. The distribu...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Xu X,Zhu H,Liu F,Zhang Y,Yang J,Zhang L,Xie Q,Zhu L,Li N,Kung HF,Yang Z

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:The high failure rates in the radiotherapy (RT) target volume suggest that patients with locally advanced oesophageal cancer (LAOC) would benefit from increased total RT doses. High 2-deoxy-2-[(18)F]fluoro-D-glucose (FDG) uptake (hotspot) on pre-RT FDG positron emission tomography (PET)/CT has been reported to ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Calais J,Dubray B,Nkhali L,Thureau S,Lemarignier C,Modzelewski R,Gardin I,Di Fiore F,Michel P,Vera P

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:To investigate dynamic ictal perfusion changes during temporal lobe epilepsy (TLE). METHODS:We investigated 37 patients with TLE by ictal and interictal SPECT. All ictal injections were performed within 60 s of seizure onset. Statistical parametric mapping was used to analyse brain perfusion changes and tempor...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Dupont P,Zaknun JJ,Maes A,Tepmongkol S,Vasquez S,Bal CS,Van Paesschen W,Carpintiero S,Locharernkul C,Dondi M

更新日期：2009-05-01 00:00:00

abstract：INTRODUCTION:Somatostatin receptor imaging with PET is the standard of care for patients with a neuroendocrine tumour (NET). Since therapy and imaging with somatostatin analogues utilize the same receptor, current guidelines recommend withdrawing long-acting somatostatin analogues for 3-4 weeks prior to somatostatin re...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Aalbersberg EA,de Wit-van der Veen BJ,Versleijen MWJ,Saveur LJ,Valk GD,Tesselaar MET,Stokkel MPM

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:Artificial neural networks (ANN) might help to diagnose coronary artery disease. This study aimed to determine whether the diagnostic accuracy of an ANN-based diagnostic system and conventional quantitation are comparable. METHODS:The ANN was trained to classify potentially abnormal areas as true or false base...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nakajima K,Kudo T,Nakata T,Kiso K,Kasai T,Taniguchi Y,Matsuo S,Momose M,Nakagawa M,Sarai M,Hida S,Tanaka H,Yokoyama K,Okuda K,Edenbrandt L

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:123I-labelled mZIENT (2β-carbomethoxy-3β-(3′-((Z)-2-iodoethenyl)phenyl)nortropane) has been developed as a radioligand for the serotonin transporter. The aim of this preliminary study was to assess its whole-body biodistribution in humans and estimate dosimetry. METHODS:Three healthy controls and three patient...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nicol A,Krishnadas R,Champion S,Tamagnan G,Stehouwer JS,Goodman MM,Hadley DM,Pimlott SL

更新日期：2012-05-01 00:00:00

abstract：:The aim of this study was to describe the anatomical structures that show uptake of the somatostatin analogue octreotide in patients with thyroid-associated orbitopathy (TAO). The study population comprised a series of 20 TAO patients attending the out-patient thyroid clinic and 12 patients presenting head or neck tum...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kainz H,Bale R,Donnemiller E,Gabriel M,Kovacs P,Decristoforo C,Moncayo R

更新日期：2003-08-01 00:00:00

abstract：PURPOSE:High-energy gamma probes have recently become commercially available, developed for (18)F-FDG probe-guided surgery. The radiation received by the staff in the operating room might limit the use of it, but has never been determined. We therefore wanted to measure the absorbed staff doses at operations where pati...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Andersen PA,Chakera AH,Klausen TL,Binderup T,Grossjohann HS,Friis E,Palnaes Hansen C,Schmidt G,Kjaer A,Hesse B

更新日期：2008-03-01 00:00:00