Value of ¹³¹I SPECT/CT for the evaluation of differentiated thyroid cancer: a systematic review of the literature.

abstract：PURPOSE:Sorafenib, an oral multikinase inhibitor, is a recommended treatment option available for patients with Barcelona Clinic Liver Cancer (BCLC)-C stage hepatocellular carcinoma (HCC). This study aimed to evaluate the performance of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) for predicting tu...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sung PS,Park HL,Yang K,Hwang S,Song MJ,Jang JW,Choi JY,Yoon SK,Yoo IR,Bae SH

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:Aortic metabolic activity is suggested to correlate with presence and progression of aneurysmal disease, but has been inadequately studied. This study investigates the 2-[(18)F] fluoro-2-deoxy-D-glucose ((18)F-FDG) uptake in a population of infra-renal abdominal aortic aneurysms (AAA), compared to a matched non...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Barwick TD,Lyons OT,Mikhaeel NG,Waltham M,O'Doherty MJ

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:Positron emission tomography (PET) radioligands specific to α7 nicotinic acetylcholine receptors (nAChRs) afford in vivo imaging of this receptor for neuropathologies such as Alzheimer's disease, schizophrenia, and substance abuse. This work aims to characterize the kinetic properties of an α7-nAChR-specific ra...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hillmer AT,Zheng MQ,Li S,Scheunemann M,Lin SF,Holden D,Labaree D,Ropchan J,Teodoro R,Deuther-Conrad W,Carson RE,Brust P,Huang Y

更新日期：2016-03-01 00:00:00

abstract：:Improvements in the specificity of radiopharmaceutical compounds have been paralleled by an upsurge of interest in developing small detectors to assist surgeons in localizing tumour tissue during surgery. This study reports the main technical features and physical characteristics of a new hand-held gamma camera dedica...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Pitre S,Ménard L,Ricard M,Solal M,Garbay JR,Charon Y

更新日期：2003-03-01 00:00:00

abstract：:The last 25 years have seen major changes in the imaging investigation and subsequent management of patients with Hodgkin's disease (HD) and non-Hodgkin's lymphoma (NHL); accurate staging is vital for prognostication and treatment in both, and particularly in HD. The choice of imaging modality for staging depends on i...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Vinnicombe SJ,Reznek RH

更新日期：2003-06-01 00:00:00

abstract：PURPOSE:The purpose of this study was to design a fully automatic computer-assisted diagnostic system for early- and late-onset mild Alzheimer's disease (AD). METHODS:Glucose metabolic images were obtained from mild AD patients and normal controls using positron emission tomography (PET) and( 18)F-fluorodeoxyglucose (...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ishii K,Kono AK,Sasaki H,Miyamoto N,Fukuda T,Sakamoto S,Mori E

更新日期：2006-05-01 00:00:00

abstract：INTRODUCTION:Somatostatin receptor imaging with PET is the standard of care for patients with a neuroendocrine tumour (NET). Since therapy and imaging with somatostatin analogues utilize the same receptor, current guidelines recommend withdrawing long-acting somatostatin analogues for 3-4 weeks prior to somatostatin re...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Aalbersberg EA,de Wit-van der Veen BJ,Versleijen MWJ,Saveur LJ,Valk GD,Tesselaar MET,Stokkel MPM

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:Left ventricular (LV) mechanical dyssynchrony (LVMD) was assessed by gated single-photon emission CT myocardial perfusion imaging (MPI) as an independent predictor of death from any cause in patients with known coronary artery disease (CAD) and reduced LV function. METHODS:Between 2001 and 2010, 135 patients (...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Uebleis C,Hellweger S,Laubender RP,Becker A,Sohn HY,Lehner S,Haug A,Bartenstein P,Cumming P,Van Kriekinge SD,Slomka PJ,Hacker M

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:This study proposes an automated prostate cancer (PC) lesion characterization method based on the deep neural network to determine tumor burden on 68Ga-PSMA-11 PET/CT to potentially facilitate the optimization of PSMA-directed radionuclide therapy. METHODS:We collected 68Ga-PSMA-11 PET/CT images from 193 patie...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Zhao Y,Gafita A,Vollnberg B,Tetteh G,Haupt F,Afshar-Oromieh A,Menze B,Eiber M,Rominger A,Shi K

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:It was previously demonstrated that radiation effects can enhance the therapy outcome of immune checkpoint inhibitors. In this study, a syngeneic breast tumor mouse model was used to investigate the effect of [177Lu]Lu-DOTA-folate as an immune stimulus to enhance anti-CTLA-4 immunotherapy. METHODS:In vitro and...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Guzik P,Siwowska K,Fang HY,Cohrs S,Bernhardt P,Schibli R,Müller C

更新日期：2020-10-19 00:00:00

abstract：PURPOSE:Multiple myeloma (MM) is a bone marrow malignancy that remains mostly incurable. Elotuzumab is an FDA-approved therapeutic monoclonal antibody targeted to the cell surface glycoprotein CS1, which is overexpressed in MM cells. Identifying patients who will respond to CS1-targeted treatments such as elotuzumab re...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ghai A,Zheleznyak A,Mixdorf M,O'Neal J,Ritchey J,Rettig M,DiPersio J,Shokeen M,Achilefu S

更新日期：2020-11-11 00:00:00

abstract：UNLABELLED:The aim of this study was to evaluate the feasibility of using [(18)F] 3'-deoxy-3'-fluorothymidine (FLT) positron emission tomography (PET) for the diagnosis and grading of brain tumors. METHODS:The patient population comprised 26 patients (15 males, 11 females) with brain tumors (n=18) or nontumorous lesio...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Choi SJ,Kim JS,Kim JH,Oh SJ,Lee JG,Kim CJ,Ra YS,Yeo JS,Ryu JS,Moon DH

更新日期：2005-06-01 00:00:00

abstract：PURPOSE:(11)C-PK11195 is a radiopharmaceutical for in vivo assessment of peripheral benzodiazepine receptor (PBR) activity using PET. We sought to clarify the metabolic fate of (11)C-PK11195 in a test-retest setting using radio-HPLC in comparison with radio-TLC, and the whole-body distribution in humans. MATERIALS AND...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Roivainen A,Någren K,Hirvonen J,Oikonen V,Virsu P,Tolvanen T,Rinne JO

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:We investigated the relationship between three-dimensional volumetric data of the metabolically active tumour volume assessed using [(11)C]-methionine positron emission tomography (MET-PET) and the area of gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA) enhancement assessed using magnetic resonance imag...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Galldiks N,Ullrich R,Schroeter M,Fink GR,Jacobs AH,Kracht LW

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:Penile cancer (PC) is a rare neoplasm with an aggressive behavior and variable prognosis. Lymph node (LN) involvement and pathological features of the primary lesion have been proven to be the most important survival factors. Positron emission tomography/computed tomography with fluorodeoxyglucose labelled with...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Salazar A,Júnior EP,Salles PGO,Silva-Filho R,Reis EA,Mamede M

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Hybrid imaging is now widely accepted in cancer imaging with increasing use of PET/CT in clinical practice. The advantages of MRI compared to CT with respect to radiation exposure and soft-tissue lesion contrast, as well as the possibility of performing more sophisticated assessment of tissue chemistry, ha...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hicks RJ,Lau EW

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:[(18)F]Fluoro-3'-deoxy-3'-L-fluorothymidine ([(18)F]FLT) is a tissue proliferation marker which has been widely validated as a tumour-specific imaging tracer for PET. [(18)F]FLT uptake in breast cancer is generally quantified at the region level or through first-order statistical descriptors (mean or maximum va...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Veronese M,Rizzo G,Aboagye EO,Bertoldo A

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:Our group has previously reported on the use of (68)Ga-ventilation/perfusion (VQ) PET/CT scanning for the diagnosis of pulmonary embolism. We describe here the acquisition methodology for (68)Ga-VQ respiratory gated (4-D) PET/CT and the effects of respiratory motion on image coregistration in VQ scanning. METH...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Callahan J,Hofman MS,Siva S,Kron T,Schneider ME,Binns D,Eu P,Hicks RJ

更新日期：2014-02-01 00:00:00

abstract：PURPOSE:We analysed a correlation between pre- to post-treatment primary tumour metabolic volume (PT-MV) reduction on 18F-FDG-PET/CT and survival in non-small cell lung cancer (NSCLC) patients treated with chemoradiotherapy (CRT). METHODS:Sixty consecutive patients with NSCLC stage IIIA-B (UICC 7th edition), treated w...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Roengvoraphoj O,Eze C,Wijaya C,Dantes M,Taugner J,Tufman A,Huber RM,Bartenstein P,Belka C,Manapov F

更新日期：2018-11-01 00:00:00

abstract：:When projection data are incomplete for various technical reasons, artefacts may occur in the reconstructed images. This study examines whether an iterative reconstruction method, the ordered subsets implementation of the EM algorithm (OSEM), can improve reconstruction and minimise the artefacts compared to filtered b...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hatton RL,Hutton BF,Angelides S,Choong KK,Larcos G

更新日期：2004-06-01 00:00:00

abstract：PURPOSE:The aim of the study was to assess the role of CA 15.3, CT and positron emission tomography (PET)/CT in patients with breast cancer and suspected disease relapse after primary treatment. METHODS:We studied 111 consecutive patients (mean age 61 ± 12 years) with previous breast cancer, already treated and with c...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Evangelista L,Baretta Z,Vinante L,Cervino AR,Gregianin M,Ghiotto C,Saladini G,Sotti G

更新日期：2011-02-01 00:00:00

abstract：:Techniques from the field of artificial intelligence, and more specifically machine (deep) learning methods, have been core components of most recent developments in the field of medical imaging. They are already being exploited or are being considered to tackle most tasks, including image reconstruction, processing (...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Visvikis D,Cheze Le Rest C,Jaouen V,Hatt M

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:To determine whether the relative metabolic activity of pelvic or para-aortic LN compared with that of primary tumor measured by preoperative [18F]FDG PET/CT scan has prognostic value in patients with endometrioid endometrial carcinoma. METHODS:We retrospectively reviewed patients with endometrioid endometrial...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Chung HH,Cheon GJ,Kim JW,Park NH,Song YS

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:In this study, we evaluate the utility of 4-[(18)F]fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide ([(18)F]FITM) as a positron emission tomography (PET) ligand for imaging of the metabotropic glutamate receptor subtype 1 (mGluR1) in rat and monkey brains. METHODS:In vivo dist...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Yamasaki T,Fujinaga M,Maeda J,Kawamura K,Yui J,Hatori A,Yoshida Y,Nagai Y,Tokunaga M,Higuchi M,Suhara T,Fukumura T,Zhang MR

更新日期：2012-04-01 00:00:00

abstract：:Transmission measurement is recommended in order to accurately correct for attenuation in myocardial single-photon emission tomography (SPET) studies. It is important that transmission studies are artefact-free, otherwise the attenuation-corrected SPET studies may also be affected. An assumption in transmission studie...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Evans SG,Hutton BF

更新日期：2004-05-01 00:00:00

abstract：PURPOSE:Tau accumulation is a core pathologic change in various neurodegenerative diseases including Alzheimer's disease and frontotemporal lobar degeneration-tau. Recently, tau positron emission tomography tracers such as [18F] AV-1451 and [18F] THK5351 have been developed to detect tau deposition in vivo. In the pres...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Jang YK,Lyoo CH,Park S,Oh SJ,Cho H,Oh M,Ryu YH,Choi JY,Rabinovici GD,Kim HJ,Moon SH,Jang H,Lee JS,Jagust WJ,Na DL,Kim JS,Seo SW

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:Standardized uptake value ratio (SUVr) used to quantify amyloid-β burden from amyloid-PET scans can be biased by variations in the tracer's nonspecific (NS) binding caused by the presence of cerebrovascular disease (CeVD). In this work, we propose a novel amyloid-PET quantification approach that harnesses the i...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Liu H,Nai YH,Saridin F,Tanaka T,O' Doherty J,Hilal S,Gyanwali B,Chen CP,Robins EG,Reilhac A

更新日期：2021-01-07 00:00:00

abstract：:Characterisation of the physical performance of the new integrated PET/CT system Discovery ST (GE Medical Systems) has been performed following the NEMA NU 2-1994 (N-94) and the NEMA NU 2-2001 (N-01) standards in both 2D and 3D acquisition configuration. The Discovery ST combines a four or eight multi-slice helical CT...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bettinardi V,Danna M,Savi A,Lecchi M,Castiglioni I,Gilardi MC,Bammer H,Lucignani G,Fazio F

更新日期：2004-06-01 00:00:00

abstract：PURPOSE:Imaging probes/biomarkers that are correlated with molecular or microenvironmental alterations in tumors have been used not only in diagnosing cancer but also in assessing the efficacy of cancer treatment. We evaluated the early response of hepatocellular carcinoma (HCC) to radiation treatment using T2-weighted...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Chung YH,Yu CF,Chiu SC,Chiu H,Hsu ST,Wu CR,Yang CL,Hong JH,Yen TC,Chen FH

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:Low sensitivity can become a major problem when very small pinholes are used in SPECT imaging. Although a larger pinhole aperture will improve the sensitivity, this will be at the cost of the spatial resolution. With a view to improving the resolution-sensitivity trade-off, this paper explores an iterative reco...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Vanhove C,Andreyev A,Defrise M,Nuyts J,Bossuyt A

更新日期：2007-02-01 00:00:00