当前位置： SCI文献检索 > EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING期刊下所有文献 > Prognostic value of lymph node-to-primary tumor standardized uptake value ratio in endometrioid endometrial carcinoma.

Prognostic value of lymph node-to-primary tumor standardized uptake value ratio in endometrioid endometrial carcinoma.

Abstract：

PURPOSE:To determine whether the relative metabolic activity of pelvic or para-aortic LN compared with that of primary tumor measured by preoperative [18F]FDG PET/CT scan has prognostic value in patients with endometrioid endometrial carcinoma. METHODS:We retrospectively reviewed patients with endometrioid endometrial carcinoma who underwent preoperative [18F]FDG PET/CT scans. Prognostic values of PET/CT-derived metabolic variables such as maximum standardized uptake value (SUV) of the primary endometrial carcinoma (SUVTumor) and LN (SUVLN), and the LN-to-endometrial carcinoma SUV ratio (SUVLN / SUVTumor) were assessed. RESULTS:Clinico-pathological data, imaging data, and treatment results were reviewed for 107 eligible patients. Median post-surgical follow-up was 23 months (range, 6-60), and 7 (6.5%) patients experienced recurrence. Regression analysis showed that SUVLN / SUVTumor (P < 0.001), SUVLN (P = 0.003), International Federation of Gynecology and Obstetrics (FIGO) stage (P = 0.006), and tumor grade (P = 0.011) were risk factors of recurrence. Multivariate regression analysis revealed that FIGO stage (P = 0.034) was the independent risk factor of recurrence. SUVLN / SUVTumor showed significant correlation with FIGO stage (P < 0.001), LN metastasis (P < 0.001), lymphovascular space invasion (P < 0.001), recurrence (P = 0.001), tumor grade (P < 0.001), and deep myometrial invasion of tumor (P = 0.022). Patient groups categorized by SUVLN / SUVTumor showed significant difference in progression-free survival (Log-rank test, P = 0.001). CONCLUSIONS:Preoperative SUVLN / SUVTumor measured by [18F]FDG PET/CT was significantly associated with recurrence, and may become a novel prognostic factor in patients with endometrioid endometrial carcinoma.

journal_name

Eur J Nucl Med Mol Imaging

journal_title

European journal of nuclear medicine and molecular imaging

authors

Chung HH,Cheon GJ,Kim JW,Park NH,Song YS

doi

10.1007/s00259-017-3805-2

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

47-55

issue

1

eissn

1619-7070

issn

1619-7089

pii

10.1007/s00259-017-3805-2

journal_volume

45

pub_type

杂志文章

相关文献

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING文献大全
  • Test-retest reproducibility of the metabotropic glutamate receptor 5 ligand [¹⁸F]FPEB with bolus plus constant infusion in humans.

    abstract：PURPOSE:[(18)F]FPEB is a promising PET radioligand for the metabotropic glutamate receptor 5 (mGluR5), a potential target for the treatment of neuropsychiatric diseases. The purpose of this study was to evaluate the test-retest reproducibility of [(18)F]FPEB in the human brain. METHODS:Seven healthy male subjects were...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-015-3094-6

    authors： Park E,Sullivan JM,Planeta B,Gallezot JD,Lim K,Lin SF,Ropchan J,McCarthy TJ,Ding YS,Morris ED,Williams WA,Huang Y,Carson RE

    更新日期：2015-09-01 00:00:00

  • The value of incomplete mouse models of Alzheimer's disease.

    abstract：:To study Alzheimer's disease (AD), a variety of mouse models has been generated through the overexpression of the amyloid precursor protein and/or the presenilins harboring one or several mutations found in familial AD. With aging, these mice develop several lesions similar to those of AD, including diffuse and neurit...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章,评审

    doi：10.1007/s00259-007-0704-y

    authors： Radde R,Duma C,Goedert M,Jucker M

    更新日期：2008-03-01 00:00:00

  • The diagnostic value of 18F-FDG PET and MRI in paediatric histiocytosis.

    abstract：PURPOSE:To analyse the diagnostic value of (18)F-FDG PET and MRI for the evaluation of active lesions in paediatric Langerhans cell histiocytosis. METHODS:We compared 21 (18)F-FDG PET scans with 21 MRI scans (mean time interval 17 days) in 15 patients (11 male, 4 female, age range 4 months to 19 years) with biopsy-pro...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-012-2278-6

    authors： Mueller WP,Melzer HI,Schmid I,Coppenrath E,Bartenstein P,Pfluger T

    更新日期：2013-02-01 00:00:00

  • Promising potential of [177Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy-a preclinical study using a syngeneic breast cancer model.

    abstract：PURPOSE:It was previously demonstrated that radiation effects can enhance the therapy outcome of immune checkpoint inhibitors. In this study, a syngeneic breast tumor mouse model was used to investigate the effect of [177Lu]Lu-DOTA-folate as an immune stimulus to enhance anti-CTLA-4 immunotherapy. METHODS:In vitro and...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-020-05054-9

    authors： Guzik P,Siwowska K,Fang HY,Cohrs S,Bernhardt P,Schibli R,Müller C

    更新日期：2020-10-19 00:00:00

  • Imaging for metabotropic glutamate receptor subtype 1 in rat and monkey brains using PET with [18F]FITM.

    abstract：PURPOSE:In this study, we evaluate the utility of 4-[(18)F]fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide ([(18)F]FITM) as a positron emission tomography (PET) ligand for imaging of the metabotropic glutamate receptor subtype 1 (mGluR1) in rat and monkey brains. METHODS:In vivo dist...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-011-1995-6

    authors： Yamasaki T,Fujinaga M,Maeda J,Kawamura K,Yui J,Hatori A,Yoshida Y,Nagai Y,Tokunaga M,Higuchi M,Suhara T,Fukumura T,Zhang MR

    更新日期：2012-04-01 00:00:00

  • Enhanced efficacy of combined 213Bi-DTPA-F3 and paclitaxel therapy of peritoneal carcinomatosis is mediated by enhanced induction of apoptosis and G2/M phase arrest.

    abstract：PURPOSE:Targeted therapy with α-particle emitting radionuclides is a promising new option in cancer therapy. Stable conjugates of the vascular tumour-homing peptide F3 with the α-emitter (213)Bi specifically target tumour cells. The aim of our study was to determine efficacy of combined (213)Bi-diethylenetriaminepentaa...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-012-2203-z

    authors： Vallon M,Seidl C,Blechert B,Li Z,Gilbertz KP,Baumgart A,Aichler M,Feuchtinger A,Gaertner FC,Bruchertseifer F,Morgenstern A,Walch AK,Senekowitsch-Schmidtke R,Essler M

    更新日期：2012-12-01 00:00:00

  • Preclinical evaluation of [18F]2FNQ1P as the first fluorinated serotonin 5-HT6 radioligand for PET imaging.

    abstract：PURPOSE:Brain serotonin 6 receptor (5-HT6) is one of the most recently identified serotonin receptors. It is a potent therapeutic target for psychiatric and neurological diseases, e.g. schizophrenia and Alzheimer's disease. Since no specific fluorinated radioligand has yet been successfully used to study this receptor ...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-014-2936-y

    authors： Becker G,Colomb J,Sgambato-Faure V,Tremblay L,Billard T,Zimmer L

    更新日期：2015-03-01 00:00:00

  • The kinetic basis of glomerular filtration rate measurement and new concepts of indexation to body size.

    abstract：:As measurement of glomerular filtration rate (GFR) is now generally the responsibility of departments of nuclear medicine, it is important for nuclear medicine physicians and scientists to understand the pharmacokinetics of the indicators and radiotracers that are used, generally known as filtration markers. The singl...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章,评审

    doi：10.1007/s00259-003-1341-8

    authors： Peters AM

    更新日期：2004-01-01 00:00:00

  • Comparison of the clinical performance of upper abdominal PET/DCE-MRI with and without concurrent respiratory motion correction (MoCo).

    abstract：PURPOSE:To compare the clinical performance of upper abdominal PET/DCE-MRI with and without concurrent respiratory motion correction (MoCo). METHODS:MoCo PET/DCE-MRI of the upper abdomen was acquired in 44 consecutive oncologic patients and compared with non-MoCo PET/MRI. SUVmax and MTV of FDG-avid upper abdominal mal...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-018-4084-2

    authors： Catalano OA,Umutlu L,Fuin N,Hibert ML,Scipioni M,Pedemonte S,Vangel M,Catana AM,Herrmann K,Nensa F,Groshar D,Mahmood U,Rosen BR,Catana C

    更新日期：2018-11-01 00:00:00

  • The effect of 18F-florbetapir dose reduction on region-based classification of cortical amyloid deposition.

    abstract：UNLABELLED:There are specific dose recommendations for diagnostic amyloid PET imaging with 18F-florbetapir, but they may not apply to research studies using regional quantitative analysis. We, therefore, studied the effect of tracer dose reduction on the discriminative power of regional analysis. METHODS:Using bootstr...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-014-2842-3

    authors： Herholz K,Evans R,Anton-Rodriguez J,Hinz R,Matthews JC

    更新日期：2014-11-01 00:00:00

  • The prognostic and predictive value of sstr2-immunohistochemistry and sstr2-targeted imaging in neuroendocrine tumors.

    abstract：PURPOSE:Our aim was to assess the prognostic and predictive value of somatostatin receptor 2 (sstr2) in neuroendocrine tumors (NETs). METHODS:We established a tissue microarray and imaging database from NET patients that received sstr2-targeted radiopeptide therapy with yttrium-90-DOTATOC, lutetium-177-DOTATOC or alte...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-016-3486-2

    authors： Brunner P,Jörg AC,Glatz K,Bubendorf L,Radojewski P,Umlauft M,Marincek N,Spanjol PM,Krause T,Dumont RA,Maecke HR,Müller-Brand J,Briel M,Schmitt A,Perren A,Walter MA

    更新日期：2017-03-01 00:00:00

  • (11)C-acetate as a new biomarker for PET/CT in patients with multiple myeloma: initial staging and postinduction response assessment.

    abstract：PURPOSE:We investigated the potential value of (11)C-acetate (ACT) PET/CT in characterizing multiple myeloma (MM) compared with (18)F-FDG PET/CT. Bone marrow histological and whole-body (WB) MRI findings served as the reference standards. METHODS:In this prospective study, 15 untreated MM patients (10 men and 5 women,...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00259-013-2520-x

    authors： Lin C,Ho CL,Ng SH,Wang PN,Huang Y,Lin YC,Tang TC,Tsai SF,Rahmouni A,Yen TC

    更新日期：2014-01-01 00:00:00

  • Memory-provoked rCBF-SPECT as a diagnostic tool in Alzheimer's disease?

    abstract：PURPOSE:Alzheimer's disease (AD) is a primary degenerative disease that progressively affects all brain functions, with devastating consequences for the patient, the patient's family and society. Rest regional cerebral blood flow (rCBF) could have a strategic role in differentiating between AD patients and normal contr...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-005-1874-0

    authors： Sundström T,Elgh E,Larsson A,Näsman B,Nyberg L,Riklund KA

    更新日期：2006-01-01 00:00:00

  • 123I-MIBG imaging detects cardiac involvement and predicts cardiac events in Churg-Strauss syndrome.

    abstract：PURPOSE:In Churg-Strauss syndrome (CSS) it is important to detect cardiac involvement, which predicts poor prognosis. This study evaluated whether (123)I-metaiodobenzylguanidine (MIBG) scintigraphy could detect cardiac damage and predict cardiac events in CSS. METHODS:(123)I-MIBG scintigraphy was performed in 28 patie...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-010-1617-8

    authors： Horiguchi Y,Morita Y,Tsurikisawa N,Akiyama K

    更新日期：2011-02-01 00:00:00

  • Consequences of radiopharmaceutical extravasation and therapeutic interventions: a systematic review.

    abstract：PURPOSE:Radiopharmaceutical extravasation can potentially lead to severe soft tissue damage, but little is known about incidence, medical consequences, possible interventions, and effectiveness of these. The aims of this study are to estimate the incidence of extravasation of diagnostic and therapeutic radiopharmaceuti...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章,评审

    doi：10.1007/s00259-017-3675-7

    authors： van der Pol J,Vöö S,Bucerius J,Mottaghy FM

    更新日期：2017-07-01 00:00:00

  • Dynamic perfusion patterns in temporal lobe epilepsy.

    abstract：PURPOSE:To investigate dynamic ictal perfusion changes during temporal lobe epilepsy (TLE). METHODS:We investigated 37 patients with TLE by ictal and interictal SPECT. All ictal injections were performed within 60 s of seizure onset. Statistical parametric mapping was used to analyse brain perfusion changes and tempor...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-008-1040-6

    authors： Dupont P,Zaknun JJ,Maes A,Tepmongkol S,Vasquez S,Bal CS,Van Paesschen W,Carpintiero S,Locharernkul C,Dondi M

    更新日期：2009-05-01 00:00:00

  • Direct comparison of (68)Ga-DOTA-TOC and (18)F-FDG PET/CT in the follow-up of patients with neuroendocrine tumour treated with the first full peptide receptor radionuclide therapy cycle.

    abstract：PURPOSE:To determine the value of (68)Ga-DOTA-TOC and (18)F-FDG PET/CT for initial and follow-up evaluation of patients with neuroendocrine tumour (NET) treated with peptide receptor radionuclide therapy (PRRT). METHODS:We evaluated 66 patients who had histologically proven NET and underwent both PRRT and three combin...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-016-3328-2

    authors： Nilica B,Waitz D,Stevanovic V,Uprimny C,Kendler D,Buxbaum S,Warwitz B,Gerardo L,Henninger B,Virgolini I,Rodrigues M

    更新日期：2016-08-01 00:00:00

  • Volumetry of [(11)C]-methionine PET uptake and MRI contrast enhancement in patients with recurrent glioblastoma multiforme.

    abstract：PURPOSE:We investigated the relationship between three-dimensional volumetric data of the metabolically active tumour volume assessed using [(11)C]-methionine positron emission tomography (MET-PET) and the area of gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA) enhancement assessed using magnetic resonance imag...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-009-1219-5

    authors： Galldiks N,Ullrich R,Schroeter M,Fink GR,Jacobs AH,Kracht LW

    更新日期：2010-01-01 00:00:00

  • Tumor delivery of antisense oligomer using trastuzumab within a streptavidin nanoparticle.

    abstract：PURPOSE:Trastuzumab (Herceptin™) is often internalized following binding to Her2+ tumor cells. The objective of this study was to investigate whether trastuzumab can be used as a specific carrier to deliver antisense oligomers into Her2+ tumor cells both in vitro and in vivo. METHODS:A biotinylated MORF oligomer antis...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-009-1201-2

    authors： Wang Y,Liu X,Chen L,Cheng D,Rusckowski M,Hnatowich DJ

    更新日期：2009-12-01 00:00:00

  • Guidelines on nuclear medicine imaging in neuroblastoma.

    abstract：:Nuclear medicine has a central role in the diagnosis, staging, response assessment and long-term follow-up of neuroblastoma, the most common solid extracranial tumour in children. These EANM guidelines include updated information on 123I-mIBG, the most common study in nuclear medicine for the evaluation of neuroblasto...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-018-4070-8

    authors： Bar-Sever Z,Biassoni L,Shulkin B,Kong G,Hofman MS,Lopci E,Manea I,Koziorowski J,Castellani R,Boubaker A,Lambert B,Pfluger T,Nadel H,Sharp S,Giammarile F

    更新日期：2018-10-01 00:00:00

  • In vivo imaging of the 18-kDa translocator protein (TSPO) with [18F]FEDAA1106 and PET does not show increased binding in Alzheimer's disease patients.

    abstract：PURPOSE:Imaging the 18-kDa translocator protein (TSPO) is considered a potential tool for in vivo evaluation of microglial activation and neuroinflammation in the early stages of Alzheimer's disease (AD). ((R)-1-(2-chlorophenyl)-N-[(11)C]-methyl-N-(1-methylpropyl)-3-isoquinoline caboxamide ([(11)C]-(R)-PK11195) has bee...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-013-2359-1

    authors： Varrone A,Mattsson P,Forsberg A,Takano A,Nag S,Gulyás B,Borg J,Boellaard R,Al-Tawil N,Eriksdotter M,Zimmermann T,Schultze-Mosgau M,Thiele A,Hoffmann A,Lammertsma AA,Halldin C

    更新日期：2013-06-01 00:00:00

  • Diagnostic accuracy of ¹¹C-choline PET/CT in comparison with CT and/or MRI in patients with hepatocellular carcinoma.

    abstract：PURPOSE:In recent decades, the use of radiopharmaceuticals in the assessment of hepatocellular carcinoma (HCC) has become established, and new findings indicate that radiolabelled choline has considerable potential in this setting. Therefore, in this study we aimed to assess the diagnostic role of (11)C-choline positro...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-015-3079-5

    authors： Lopci E,Torzilli G,Poretti D,de Neto LJ,Donadon M,Rimassa L,Lanza E,Sabongi JG,Ceriani R,Personeni N,Palmisano A,Pedicini V,Comito T,Scorsetti M,Chiti A

    更新日期：2015-08-01 00:00:00

  • Dose-response relationship in cyclophosphamide-treated B-cell lymphoma xenografts monitored with [18F]FDG PET.

    abstract：PURPOSE:Although [(18)F]FDG PET can measure therapy response sooner and more accurately than morphological imaging techniques, there is still some debate as to whether [(18)F]FDG uptake really reflects changes in the viable cell fraction. In this study changes in [(18)F]FDG uptake were investigated in a lymphoma model ...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-010-1479-0

    authors： Brepoels L,De Saint-Hubert M,Stroobants S,Verhoef G,Balzarini J,Mortelmans L,Mottaghy FM

    更新日期：2010-08-01 00:00:00

  • Whole-body distribution and metabolism of [N-methyl-11C](R)-1-(2-chlorophenyl)-N-(1-methylpropyl)-3-isoquinolinecarboxamide in humans; an imaging agent for in vivo assessment of peripheral benzodiazepine receptor activity with positron emission tomography

    abstract：PURPOSE:(11)C-PK11195 is a radiopharmaceutical for in vivo assessment of peripheral benzodiazepine receptor (PBR) activity using PET. We sought to clarify the metabolic fate of (11)C-PK11195 in a test-retest setting using radio-HPLC in comparison with radio-TLC, and the whole-body distribution in humans. MATERIALS AND...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-008-1000-1

    authors： Roivainen A,Någren K,Hirvonen J,Oikonen V,Virsu P,Tolvanen T,Rinne JO

    更新日期：2009-04-01 00:00:00

  • Electrocardiographic-gated dual-isotope simultaneous acquisition SPECT using 18F-FDG and 99mTc-sestamibi to assess myocardial viability and function in a single study.

    abstract：PURPOSE:Dual-isotope simultaneous acquisition single-photon emission computed tomography (DISA SPECT) with 18F-fluorodeoxyglucose (FDG) and (99m)Tc-sestamibi appears attractive for the detection of viable myocardium because it permits simultaneous assessment of glucose utilisation and perfusion. Another potential benef...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00259-004-1668-9

    authors： Matsunari I,Kanayama S,Yoneyama T,Matsudaira M,Nakajima K,Taki J,Nekolla SG,Tonami N,Hisada K

    更新日期：2005-02-01 00:00:00

  • A randomized, double-blind, crossover comparison of novel continuous bed motion versus traditional bed position whole-body PET/CT imaging.

    abstract：PURPOSE:Continuous bed motion has recently been introduced for whole-body PET/CT, and represents a paradigm shift towards individualized and flexible acquisition without the limitations of bed position-based planning. Increased patient comfort due to lack of abrupt table position changes may be another albeit still unp...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s00259-015-3226-z

    authors： Schatka I,Weiberg D,Reichelt S,Owsianski-Hille N,Derlin T,Berding G,Bengel FM

    更新日期：2016-04-01 00:00:00

  • Ictal brain SPET during seizures pharmacologically provoked with pentylenetetrazol: a new diagnostic procedure in drug-resistant epileptic patients.

    abstract：:Functional brain imaging plays an important role in seizure focus localisation. However, truly ictal single-photon emission tomography (SPET) studies are not routinely performed owing to technical problems associated with the use of tracers and methodological and logistical difficulties. In this study we tried to reso...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00259-002-0879-1

    authors： Calcagni ML,Giordano A,Bruno I,Parbonetti G,Di Giuda D,De Rossi G,Troncone L,Colicchio G

    更新日期：2002-10-01 00:00:00

  • Clinical impact of follicular oncocytic (Hürthle cell) carcinoma in comparison with corresponding classical follicular thyroid carcinoma.

    abstract：PURPOSE:There are controversial debates if patients with Hürthle cell carcinoma, also known as oxyphilic or oncocytic cell follicular thyroid carcinoma, have a poorer outcome. In this study, we systematically evaluated the clinical outcome in a large patient cohort following thyroidectomy and initial I-131 radioactive ...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-020-04952-2

    authors： Wenter V,Albert NL,Unterrainer M,Ahmaddy F,Ilhan H,Jellinek A,Knösel T,Bartenstein P,Spitzweg C,Lehner S,Todica A

    更新日期：2021-02-01 00:00:00

  • Presynaptic dopamine depletion determines the timing of levodopa-induced dyskinesia onset in Parkinson's disease.

    abstract：PURPOSE:Reduced presynaptic dopaminergic activity plays an important role in the development of levodopa-induced dyskinesia (LID) in Parkinson's disease (PD). In this study, we investigated whether dopaminergic function in the nigrostriatal system is associated with the timing of LID onset. METHODS:From among 412 drug...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-017-3844-8

    authors： Yoo HS,Chung SJ,Chung SJ,Moon H,Oh JS,Kim JS,Hong JY,Ye BS,Sohn YH,Lee PH

    更新日期：2018-03-01 00:00:00

  • Delayed response after repeated 177Lu-PSMA-617 radioligand therapy in patients with metastatic castration resistant prostate cancer.

    abstract：PURPOSE:Radioligand therapy (RLT) using Lutetium-177 labeled PSMA-617 (Lu-PSMA) ligand is a new therapeutic option for salvage therapy in heavily pretreated patients with metastatic castration resistant prostate cancer. The aim of this retrospective study was to analyze response in patients receiving 3 cycles of Lu-PSM...

    journal_title：European journal of nuclear medicine and molecular imaging

    pub_type： 杂志文章

    doi：10.1007/s00259-017-3877-z

    authors： Rahbar K,Bögeman M,Yordanova A,Eveslage M,Schäfers M,Essler M,Ahmadzadehfar H

    更新日期：2018-02-01 00:00:00