[(11)C]TASP457, a novel PET ligand for histamine H3 receptors in human brain.

abstract：PURPOSE:To determine the impact on clinical management of patients with high-risk (HR) prostate cancer at diagnosis and patients with biochemical recurrence (BCR) using a new kit form of 68Ga-prostate-specific membrane antigen (PSMA), namely tris(hydroxypyridinone) (THP)-PSMA, with positron emission tomography-computed...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kulkarni M,Hughes S,Mallia A,Gibson V,Young J,Aggarwal A,Morris S,Challacombe B,Popert R,Brown C,Cathcart P,Dasgupta P,Warbey VS,Cook GJR

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:PET imaging has been recently introduced for investigating the type 1 angiotensin II receptor (AT(1)R) in vivo. The goal of the present study was to investigate the effects of acute and chronic exposure to angiotensin converting enzyme inhibitors (ACEI) on the AT(1)R in the dog kidney. METHODS:Animals were ima...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Zober TG,Fabucci ME,Zheng W,Brown PR,Seckin E,Mathews WB,Sandberg K,Szabo Z

更新日期：2008-06-01 00:00:00

abstract：PURPOSE:This meta-analysis summarized the accuracy of stress myocardial perfusion scintigraphy (MPS) and stress echocardiography for the diagnosis of coronary artery disease (CAD) in patients with arterial hypertension. METHODS:We searched for studies in which stress MPS or stress echocardiography were performed to de...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Gargiulo P,Petretta M,Bruzzese D,Cuocolo A,Prastaro M,D'Amore C,Vassallo E,Savarese G,Marciano C,Paolillo S,Filardi PP

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:Invasive fungal infections (IFIs) are common in immunocompromised patients. While early diagnosis can reduce otherwise high morbidity and mortality, conventional CT has suboptimal sensitivity and specificity. Small studies have suggested that the use of FDG PET/CT may improve the ability to detect IFI. The obje...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Douglas AP,Thursky KA,Worth LJ,Drummond E,Hogg A,Hicks RJ,Slavin MA

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:The aim of the study was to assess the role of myocardial perfusion scintigraphy (MPS) in the prediction of future cardiac events in elderly hypertensive patients and to investigate if its prognostic value is maintained during a 10-year follow-up period. METHODS:A total of 229 consecutive patients ≥ 65 years o...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nai Fovino L,Saladini G,Cervino AR,Saladini F,Gregianin M,Razzolini R,Evangelista L

更新日期：2012-10-01 00:00:00

abstract：:Chronic cigarette smoking alters coronary vascular endothelial response. To determine whether altered response also occurs in young individuals without manifest coronary disease we quantified coronary blood flow at rest, following adenosine vasodilator stress and during the cold pressor test in healthy young smokers. ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Iwado Y,Yoshinaga K,Furuyama H,Ito Y,Noriyasu K,Katoh C,Kuge Y,Tsukamoto E,Tamaki N

更新日期：2002-08-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate the impact of [18F]fluorodeoxy-D-glucose positron emission tomography (FDG-PET) on the primary staging of patients with small-cell lung cancer (SCLC). METHODS:FDG-PET was performed in 120 consecutive patients with SCLC during primary staging. In addition, brain examina...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Brink I,Schumacher T,Mix M,Ruhland S,Stoelben E,Digel W,Henke M,Ghanem N,Moser E,Nitzsche EU

更新日期：2004-12-01 00:00:00

abstract：PURPOSE:Prostate stem cell antigen (PSCA), a cell surface glycoprotein expressed in normal human prostate and bladder, is over-expressed in the majority of localized prostate cancer and most bone metastases. We have previously shown that the hu1G8 minibody, a humanized anti-PSCA antibody fragment (single-chain Fv-C(H)3...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Lepin EJ,Leyton JV,Zhou Y,Olafsen T,Salazar FB,McCabe KE,Hahm S,Marks JD,Reiter RE,Wu AM

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:Positron emission tomography (PET) has been widely utilized in the study of traumatic brain injury (TBI) for decades. While most applications of PET have attempted to assess neuronal function after TBI, more recently, novel radiotracers have sought to image biomarkers in the context of TBI and chronic traumatic...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ayubcha C,Revheim ME,Newberg A,Moghbel M,Rojulpote C,Werner TJ,Alavi A

更新日期：2021-02-01 00:00:00

abstract：PURPOSE:To review literature until November 2015 and reach a consensus on whether automatic semi-quantification of brain FDG-PET is useful in the clinical setting for neurodegenerative disorders. METHODS:A literature search was conducted in Medline, Embase, and Google Scholar. Papers were selected with a lower limit o...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nobili F,Festari C,Altomare D,Agosta F,Orini S,Van Laere K,Arbizu J,Bouwman F,Drzezga A,Nestor P,Walker Z,Boccardi M,EANM-EAN Task Force for the Prescription of FDG-PET for Dementing Neurodegenerative Disorders.

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:To assess diagnostic accuracy of (18)F-FDG PET/CT at 3 months for the detection of local recurrence after radiofrequency ablation (RFA) of lung metastases. METHODS:The PET/CT scan at 3 months was compared with a baseline PET/CT scan from a maximum of 2 months before RFA, with the reference standard as recurren...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bonichon F,Palussière J,Godbert Y,Pulido M,Descat E,Devillers A,Meunier C,Leboulleux S,de Baère T,Galy-Lacour C,Lagoarde-Segot L,Cazeau AL

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:This study evaluated the usefulness of the maximum standardized uptake value (SUVmax) as a measure of histologic response to neoadjuvant chemotherapy in patients with extremity osteosarcoma. The correlation between [(18) F]FDG PET SUVmax values and histologic response to preoperative chemotherapy was also asses...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kong CB,Byun BH,Lim I,Choi CW,Lim SM,Song WS,Cho WH,Jeon DG,Koh JS,Yoo JY,Lee SY

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:Standardized uptake value ratio (SUVr) used to quantify amyloid-β burden from amyloid-PET scans can be biased by variations in the tracer's nonspecific (NS) binding caused by the presence of cerebrovascular disease (CeVD). In this work, we propose a novel amyloid-PET quantification approach that harnesses the i...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Liu H,Nai YH,Saridin F,Tanaka T,O' Doherty J,Hilal S,Gyanwali B,Chen CP,Robins EG,Reilhac A

更新日期：2021-01-07 00:00:00

abstract：PURPOSE:The objective of this article is to present a new method for the diagnosis of insulinoma with the use of [Lys(40)(Ahx-HYNIC-(99m)Tc/EDDA)NH2]-exendin-4. METHODS:Studies were performed in 11 patients with negative results of all available non-isotopic diagnostic methods (8 with symptoms of insulinoma, 2 with ma...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sowa-Staszczak A,Pach D,Mikołajczak R,Mäcke H,Jabrocka-Hybel A,Stefańska A,Tomaszuk M,Janota B,Gilis-Januszewska A,Małecki M,Kamiński G,Kowalska A,Kulig J,Matyja A,Osuch C,Hubalewska-Dydejczyk A

更新日期：2013-04-01 00:00:00

abstract：INTRODUCTION:Bone pain is a common symptom of metastatic disease in cancer, experienced with various intensities by about 30% of cancer patients, during the development of their disease, up to 60-90% in the latest phases. DISCUSSION:In addition to other therapies, such as analgesics, bisphosphonates, chemotherapy, hor...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bodei L,Lam M,Chiesa C,Flux G,Brans B,Chiti A,Giammarile F,European Association of Nuclear Medicine (EANM).

更新日期：2008-10-01 00:00:00

abstract：INTRODUCTION:Vascular prosthesis infection (VPI) is a life-threatening complication that occurs in 0.5-5% of prostheses. Low-grade infections in non-acute patients are a diagnostic challenge requiring a new method with good diagnostic accuracy. The aim of this work was to define the accuracy of (18)F-FDG PET/CT in thes...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Spacek M,Belohlavek O,Votrubova J,Sebesta P,Stadler P

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:Continuous bed motion has recently been introduced for whole-body PET/CT, and represents a paradigm shift towards individualized and flexible acquisition without the limitations of bed position-based planning. Increased patient comfort due to lack of abrupt table position changes may be another albeit still unp...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Schatka I,Weiberg D,Reichelt S,Owsianski-Hille N,Derlin T,Berding G,Bengel FM

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:The intra-arterial administration of 90Y microspheres is a new palliative treatment option for unresectable liver metastases. The aim of this study was to quantitatively assess changes in FDG uptake and tumour size following 90Y microsphere treatment (SIR-Spheres) using 18F-fluorodeoxyglucose (FDG) PET/CT imagi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bienert M,McCook B,Carr BI,Geller DA,Sheetz M,Tutor C,Amesur N,Avril N

更新日期：2005-07-01 00:00:00

abstract：:An ordered subsets (OS) reconstruction algorithm based on the median root prior (MRP) and inter-update median filtering was implemented for the reconstruction of low count statistics transmission (TR) scans. The OS-MRP-TR algorithm was evaluated using an experimental phantom, simulating positron emission tomography (P...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bettinardi V,Alenius S,Numminen P,Teräs M,Gilardi MC,Fazio F,Ruotsalainen U

更新日期：2003-02-01 00:00:00

abstract：PURPOSE:Low sensitivity can become a major problem when very small pinholes are used in SPECT imaging. Although a larger pinhole aperture will improve the sensitivity, this will be at the cost of the spatial resolution. With a view to improving the resolution-sensitivity trade-off, this paper explores an iterative reco...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Vanhove C,Andreyev A,Defrise M,Nuyts J,Bossuyt A

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:Post-transplant lymphoproliferative disorder (PTLD) is a serious complication after solid organ and hematopoietic stem cell transplantation, requiring a timely and accurate diagnosis. In this study, we evaluated the diagnostic performance of FDG-PET/CT in patients with suspected PTLD and examined if lactate deh...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Montes de Jesus FM,Kwee TC,Kahle XU,Nijland M,van Meerten T,Huls G,Dierckx RAJO,Rosati S,Diepstra A,van der Bij W,Verschuuren EAM,Glaudemans AWJM,Noordzij W

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:Aortic metabolic activity is suggested to correlate with presence and progression of aneurysmal disease, but has been inadequately studied. This study investigates the 2-[(18)F] fluoro-2-deoxy-D-glucose ((18)F-FDG) uptake in a population of infra-renal abdominal aortic aneurysms (AAA), compared to a matched non...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Barwick TD,Lyons OT,Mikhaeel NG,Waltham M,O'Doherty MJ

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare image quality and lesion detection capability between a digital and an analog PET/CT system in oncological patients. MATERIALS AND METHODS:One hundred oncological patients (62 men, 38 women; mean age of 65 ± 12 years) were prospectively included from January-June 2018...

journal_title：European journal of nuclear medicine and molecular imaging

authors： López-Mora DA,Flotats A,Fuentes-Ocampo F,Camacho V,Fernández A,Ruiz A,Duch J,Sizova M,Domènech A,Estorch M,Carrió I

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:To test the performance of sequential 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in predicting survival after sunitinib therapies in patients with cancer of unknown primary (CUP). METHODS:CUP patients were enrolled for sequential PET/CT scanning for sunitinib and a con...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ma Y,Xu W,Bai R,Li Y,Yu H,Yang C,Shi H,Zhang J,Li J,Wang C,Xiao J

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:Enlarged perivascular spaces in the centrum semiovale (CSO-EPVS) have been linked to cerebral amyloid angiopathy (CAA). To get insight into the underlying mechanisms of this association, we investigated the relationship between amyloid-β deposition assessed by 18F-florbetapir PET and CSO-EPVS in patients with a...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Raposo N,Planton M,Payoux P,Péran P,Albucher JF,Calviere L,Viguier A,Rousseau V,Hitzel A,Chollet F,Olivot JM,Bonneville F,Pariente J

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:A targeted theragnostic approach based on increased expression of prostate-specific membrane antigen (PSMA) on PC cells is an attractive treatment option for patients with metastatic castration-resistant prostate cancer (mCRPC). METHODS:Ten consecutive mCRPC patients were selected for 177Lu-PSMA617 therap...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Scarpa L,Buxbaum S,Kendler D,Fink K,Bektic J,Gruber L,Decristoforo C,Uprimny C,Lukas P,Horninger W,Virgolini I

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:Depression is a common symptom in patients suffering from Parkinson's disease (PD) and markedly reduces their quality of life. As post-mortem studies have shown, its presence may reflect extensive cell loss in the midbrain and brainstem with imbalances in monoaminergic neurotransmitters. However, in vivo eviden...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hesse S,Meyer PM,Strecker K,Barthel H,Wegner F,Oehlwein C,Isaias IU,Schwarz J,Sabri O

更新日期：2009-03-01 00:00:00

abstract：:Nuclear medicine techniques are becoming more important in imaging oncological and infectious diseases. For metabolic imaging of these diseases, antibody and peptide imaging are currently used. In recent years peptide imaging has become important, therefore the rationale for the use of peptide imaging is described in ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Koopmans KP,Glaudemans AW

更新日期：2012-02-01 00:00:00

abstract：PURPOSE:In children with Hodgkin's disease and non-Hodgkin's lymphoma, the ability of (18)F-fluoro-2-deoxy-D-glucose PET/CT and conventional imaging (CI) to detect malignant lesions and predict poor lesion response to therapy was assessed and compared. METHODS:A retrospective review of findings reported on PET/CT and ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： London K,Cross S,Onikul E,Dalla-Pozza L,Howman-Giles R

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Following brain cancer treatment, the capacity of anatomical MRI to differentiate neoplastic tissue from treatment-related changes (e.g., pseudoprogression) is limited. This study compared apparent diffusion coefficients (ADC) obtained by diffusion-weighted MRI (DWI) with static and dynamic parameters of O-(...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Werner JM,Stoffels G,Lichtenstein T,Borggrefe J,Lohmann P,Ceccon G,Shah NJ,Fink GR,Langen KJ,Kabbasch C,Galldiks N

更新日期：2019-08-01 00:00:00