Public goods and metabolic strategies.

abstract：:During the past ten years, species-rich nations in the developing world have sought to capitalize on their 'biological patrimony' through a variety of business relationships with multinational corporations as a means of underwriting their conservation efforts. Initially lauded, these relationships have generated more ...

journal_title：Current opinion in microbiology

authors： Garrity GM,Hunter-Cevera J

更新日期：1999-06-01 00:00:00

abstract：:Mast cells (MCs) have been implicated in orchestrating the host's early innate immune and adaptive immune responses in several models of acute bacterial infections. Most of this activity results in early clearance of the bacteria and timely resolution of infection. However, during chronic infections because of the pro...

journal_title：Current opinion in microbiology

authors： Chan CY,St John AL,Abraham SN

更新日期：2012-02-01 00:00:00

abstract：:Bacterium-host interactions are important for diverse ecological settings including pathogenicity and symbiosis. Electron cryotomography is a powerful method for studying the macromolecular complexes that mediate such interactions in situ. The main limitation of electron cryotomography is its restriction to relatively...

journal_title：Current opinion in microbiology

authors： Medeiros JM,Böck D,Pilhofer M

更新日期：2018-06-01 00:00:00

abstract：:In part, members of the genus Streptomyces have been studied because they produce many important secondary metabolites with antibiotic activity and for the interest in their relatively elaborate life cycle. These sporulating filamentous bacteria are remarkably synchronous for division and genome segregation in special...

journal_title：Current opinion in microbiology

authors： McCormick JR

更新日期：2009-12-01 00:00:00

abstract：:Sensing its changing environment is key for Vibrio cholerae when making the transition from an aquatic lifestyle to one more suited to a human host. An inverse correlation between motility and virulence gene expression has been reported, with the NADH : ubiquinone oxidoreductase system which powers motility by generat...

journal_title：Current opinion in microbiology

authors： Krukonis ES,DiRita VJ

更新日期：2003-04-01 00:00:00

abstract：:Stan Falkow looked at the world with his eyes peering from the outer membrane of a gram-negative bacterium. It was a great vantage point from which to dream about the possible superpowers these organisms might have. He mused about these dreams with his trainees who sometimes found through rigorous scientific explorati...

journal_title：Current opinion in microbiology

authors： Starnbach MN

更新日期：2020-04-01 00:00:00

abstract：:Virulence gene regulators RovA, SlyA and PecS comprise a subset of the MarR/SlyA family of transcriptional regulators, which has been shown to be involved in the regulation of virulence genes. These regulators have all been shown to both positively and negatively regulate the expression of multiple genes, involving se...

journal_title：Current opinion in microbiology

authors： Ellison DW,Miller VL

更新日期：2006-04-01 00:00:00

abstract：:Phagocytic cells, including macrophages, neutrophils and dendritic cells, are critical components of the innate immune response to bacterial pathogens such as Salmonella typhimurium. These cells can have several roles during the early stage of an infection including controlling bacterial replication and producing cyto...

journal_title：Current opinion in microbiology

authors： Wick MJ

更新日期：2004-02-01 00:00:00

abstract：:Recent studies on antibacterials have focused on the development of antimycobacterial agents and antibacterial peptides, and on furthering the understanding of agents that have been available for several decades, including imidazoles, beta-lactams and quinolones. New areas of research include antisense oligonucleotide...

journal_title：Current opinion in microbiology

authors： Piddock LJ

更新日期：1998-10-01 00:00:00

abstract：:Clustered, regularly interspaced, short, palindromic repeats (CRISPR) loci, together with their CRISPR-associated (Cas) proteins, provide bacteria and archaea with adaptive immunity against invasion by bacteriophages, plasmids, and other mobile genetic elements. These host defenses impart selective pressure on phages ...

journal_title：Current opinion in microbiology

authors： Sontheimer EJ,Davidson AR

更新日期：2017-06-01 00:00:00

abstract：:The emerging human pathogen Bartonella henselae has the remarkable capacity to colonise vascular tissues and to stimulate vasoproliferative tumour growth. Although the molecular principle of bacterium-induced neovascularisation (angiogenesis) is still unclear, recent studies have indicated a novel mechanism of endothe...

journal_title：Current opinion in microbiology

authors： Dehio C

更新日期：1999-02-01 00:00:00

abstract：:The protozoan parasite Trypanosoma brucei is the causative agent of African sleeping sickness and the wasting disease, nagana, in cattle. The parasite is transmitted to the mammalian host by the bite of a tsetse fly. These parasites lack transcriptional regulation, and their gene expression is mainly regulated post-tr...

journal_title：Current opinion in microbiology

authors： Michaeli S

更新日期：2014-08-01 00:00:00

abstract：:In the process of yeast budding, an aged and deteriorated mother cell gives rise to a youthful and pristine daughter cell. This remarkable event offers a tractable model system for identifying factors affecting life expectancy and it has been established that multiple aging factors operate in parallel. Herein, we will...

journal_title：Current opinion in microbiology

authors： Nyström T,Liu B

更新日期：2014-04-01 00:00:00

abstract：:Mosquitoes are the major arthropod vectors of human diseases such as malaria and viral encephalitis. However, each mosquito species does not transmit every pathogen, owing to reasons that include specific evolutionary histories, mosquito immune system structure, and ecology. Even a competent vector species for a patho...

journal_title：Current opinion in microbiology

authors： Mitri C,Vernick KD

更新日期：2012-06-01 00:00:00

abstract：:Despite the widespread availability of genome sequences and the systematic assignment of individual open reading frames, many of the activities of metabolic enzymes are still veiled. It is difficult to assign biochemical functions to enzymes and uncover the in vivo regulation of their enzymatic activities, but this is...

journal_title：Current opinion in microbiology

authors： Saito N,Ohashi Y,Soga T,Tomita M

更新日期：2010-06-01 00:00:00

abstract：:The three dimensional ultrastructure of cells and tissues comes to light with tomography. There is an inherent tension between representing molecular detail at the highest possible resolution, on one hand, and visualizing spatial relations between large organelles or even neighboring cells in large volumes, on the oth...

journal_title：Current opinion in microbiology

authors： Elbaum M

更新日期：2018-06-01 00:00:00

abstract：:Biofilm development and quorum sensing (QS) are closely interconnected processes. Biofilm formation is a cooperative group behaviour that involves bacterial populations living embedded in a self-produced extracellular matrix. QS is a cell-cell communication mechanism that synchronizes gene expression in response to po...

journal_title：Current opinion in microbiology

authors： Solano C,Echeverz M,Lasa I

更新日期：2014-04-01 00:00:00

abstract：:An understanding of the molecular bases of pathogenicity in Blastomyces dermatitidis and related systemic dimorphic fungi has been limited until recent years. Yeast cells of B. dermatitidis display an adhesion promoting protein termed WI-1. Recent studies entailing homologous gene targeting and mutation of WI-1 have p...

journal_title：Current opinion in microbiology

authors： Klein BS

更新日期：2000-08-01 00:00:00

abstract：:Endosymbiotic theory goes back over 100 years. It explains the similarity of chloroplasts and mitochondria to free-living prokaryotes by suggesting that the organelles arose from prokaryotes through (endo)symbiosis. Gene trees provide important evidence in favour of symbiotic theory at a coarse-grained level, but the ...

journal_title：Current opinion in microbiology

authors： Zimorski V,Ku C,Martin WF,Gould SB

更新日期：2014-12-01 00:00:00

abstract：:Wastewater bioreactors have been used to treat domestic and industrial waste for nearly a century. Development of molecular tools such as PCR and DNA microarrays have enabled identification and characterization of some of the microbes in these bioreactors; however, molecular characterization of the microbes is still i...

journal_title：Current opinion in microbiology

authors： Bramucci M,Nagarajan V

更新日期：2006-06-01 00:00:00

abstract：:Selective autophagy is an important effector mechanism of cell autonomous immunity, in particular against invasive bacterial species. Anti-bacterial autophagy is activated by rupture of bacteria-containing vacuoles and exposure of bacteria to the cytosol. The autophagy cargo receptors p62, NDP52 and Optineurin detect ...

journal_title：Current opinion in microbiology

authors： Boyle KB,Randow F

更新日期：2013-06-01 00:00:00

abstract：:Motile bacteria seek optimal living habitats by following gradients of attractant and repellent chemicals in their environment. The signaling machinery for these chemotactic behaviors, although assembled from just a few protein components, has extraordinary information-processing capabilities. Escherichia coli, the be...

journal_title：Current opinion in microbiology

authors： Parkinson JS,Ames P,Studdert CA

更新日期：2005-04-01 00:00:00

abstract：:Activation of professional phagocytes with the concomitant generation of oxidant species is a medullar innate immune process for the control of acute Trypanosoma cruzi infection. Recent data reinforce the hypothesis that parasites more prepared to deal with the host-oxidative assault are more efficient for the establi...

journal_title：Current opinion in microbiology

authors： Piacenza L,Alvarez MN,Peluffo G,Radi R

更新日期：2009-08-01 00:00:00

abstract：:DNA translocases play important roles during the bacterial cell cycle and in cell differentiation. Escherichia coli cells contain a multifunctional translocase, FtsK, which is involved in cell division, late steps of chromosome segregation and dimer resolution. In Gram-positive bacteria, the latter two processes are a...

journal_title：Current opinion in microbiology

authors： Kaimer C,Graumann PL

更新日期：2011-12-01 00:00:00

abstract：:Since the publication of the complete genome sequence of Mycobacterium tuberculosis in 1998, there has been a marked intensification and diversification of activities in the field of tuberculosis research. Among the areas that have advanced spectacularly are comparative genomics, functional genomics-notably the study ...

journal_title：Current opinion in microbiology

authors： Domenech P,Barry CE 3rd,Cole ST

更新日期：2001-02-01 00:00:00

abstract：:Eukaryotes host numerous intracellular and associated microbes in their microbiota. Fungi, the so-called Mycobiota, are important members of both human and plant microbiota. Moreover, members of the plant mycobiota host their own microbiota on their surfaces and inside their hyphae. The microbiota of the mycobiota inc...

journal_title：Current opinion in microbiology

authors： Bonfante P,Venice F,Lanfranco L

更新日期：2019-06-01 00:00:00

abstract：:Some of the most successful drugs in the antibiotic pharmacopeia are those that inhibit bacterial cell wall biosynthesis. However, the worldwide spread of bacterial antibiotic resistance has eroded the clinical efficacy of these drugs and the antibiotic pipeline continues to be lean as drug discovery programs struggle...

journal_title：Current opinion in microbiology

authors： Gale RT,Brown ED

更新日期：2015-10-01 00:00:00

abstract：:Mycobacterium tuberculosis (Mtb) is highly immunogenic and appears to have evolved to preserve its antigenicity. The retention of antigenicity is important to the maintenance of a robust immune response that contributes greatly to the late-stage tissue damage required for transmission and completion of the pathogen's ...

journal_title：Current opinion in microbiology

authors： Russell DG

更新日期：2013-02-01 00:00:00

abstract：:For many Gram-negative bacteria, like Brucella, the type IV secretion system (T4SS) has a critical role in bacterial virulence. In Brucella, the VirB T4SS permits the injection of bacterial effectors inside host cells, leading to subversion of signaling pathways and favoring bacterial growth and pathogenesis. The virB...

journal_title：Current opinion in microbiology

authors： Lacerda TL,Salcedo SP,Gorvel JP

更新日期：2013-02-01 00:00:00

abstract：:RNA sequencing has emerged as the premier approach to study bacterial transcriptomes. While the earliest published studies analyzed the data qualitatively, the data are readily digitized and lend themselves to quantitative analysis. High-resolution RNA sequence (RNA-seq) data allows transcriptional features (promoters...

journal_title：Current opinion in microbiology

authors： Creecy JP,Conway T

更新日期：2015-02-01 00:00:00