Abstract：
:Retinal detachment is an important cause of visual loss. Currently, surgical techniques, including vitrectomy, scleral buckle, and pneumatic retinopexy, are the only means to repair retinal detachment and restore vision. However, surgical failure rates may be as high as 20%, and visual outcomes continue to vary secondary to multiple processes, including postoperative cystoid macular edema, epiretinal membrane formation, macular folds, and, ultimately, photoreceptor death. Therefore, pharmacotherapies are being sought to aid the success rates of modern surgical techniques and reduce or slow the degeneration of photoreceptors during retinal detachment. This review discusses potential therapeutic avenues that aid in retinal reattachment, reduce the rate of retinal redetachment by limiting proliferative vitreoretinopathy, and protect against photoreceptor cell death.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Wubben TJ,Besirli CG,Zacks DNdoi
10.1016/j.ophtha.2016.02.040subject
Has Abstractpub_date
2016-07-01 00:00:00pages
1553-62issue
7eissn
0161-6420issn
1549-4713pii
S0161-6420(16)00327-4journal_volume
123pub_type
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