Electrically driven monolithic subwavelength plasmonic interconnect circuits.

abstract：:About 40% of patients with non-small cell lung cancer (NSCLC) have stage IV cancer at the time of diagnosis. The only viable treatment options for metastatic disease are systemic chemotherapy and immunotherapy. Nonetheless, chemoresistance remains a major cause of chemotherapy failure. New immunotherapeutic modalities...

journal_title：Science advances

authors： Vinod N,Hwang D,Azam SH,Van Swearingen AED,Wayne E,Fussell SC,Sokolsky-Papkov M,Pecot CV,Kabanov AV

更新日期：2020-06-17 00:00:00

abstract：:Using a national longitudinal survey data set from the Higher Education Research Institute, this study tested whether students who identified as a sexual minority (for example, lesbian, gay, bisexual, or queer) were more or less likely to persist after 4 years in science, technology, engineering, and mathematics (STEM...

journal_title：Science advances

authors： Hughes BE

更新日期：2018-03-14 00:00:00

abstract：:Nanomaterials often surprise us with unexpected phenomena. Here, we report a discovery of the anti-twinning deformation, previously thought impossible, in nanoscale body-centered cubic (BCC) tungsten crystals. By conducting in situ transmission electron microscopy nanomechanical testing, we observed the nucleation and...

journal_title：Science advances

authors： Wang J,Zeng Z,Wen M,Wang Q,Chen D,Zhang Y,Wang P,Wang H,Zhang Z,Mao SX,Zhu T

更新日期：2020-06-03 00:00:00

abstract：:The Late Paleogene surface height and paleoenvironment for the core area of the Qinghai-Tibetan Plateau (QTP) remain critically unresolved. Here, we report the discovery of the youngest well-preserved fossil palm leaves from Tibet. They were recovered from the Late Paleogene (Chattian), ca. 25.5 ± 0.5 million years, p...

journal_title：Science advances

authors： Su T,Farnsworth A,Spicer RA,Huang J,Wu FX,Liu J,Li SF,Xing YW,Huang YJ,Deng WY,Tang H,Xu CL,Zhao F,Srivastava G,Valdes PJ,Deng T,Zhou ZK

更新日期：2019-03-06 00:00:00

abstract：:We analyze a collection of empirical networks in a wide spectrum of disciplines and show that strong non-normality is ubiquitous in network science. Dynamical processes evolving on non-normal networks exhibit a peculiar behavior, as initial small disturbances may undergo a transient phase and be strongly amplified in ...

journal_title：Science advances

authors： Asllani M,Lambiotte R,Carletti T

更新日期：2018-12-12 00:00:00

abstract：:A novel, thin-film platform that preserves live viruses, bacteria, antibodies, and enzymes without refrigeration for extended periods of time is described. Studies with recombinant adenovirus in an optimized formulation that supports recovery of live virus through 16 freeze-thaw cycles revealed that production of an a...

journal_title：Science advances

authors： Bajrovic I,Schafer SC,Romanovicz DK,Croyle MA

更新日期：2020-03-04 00:00:00

abstract：:Animals, humans, and multi-robot systems operate in dynamic environments, where the ability to respond to changing circumstances is paramount. An effective collective response requires suitable information transfer among agents and thus critically depends on the interaction network. To investigate the influence of the...

journal_title：Science advances

authors： Mateo D,Horsevad N,Hassani V,Chamanbaz M,Bouffanais R

更新日期：2019-04-03 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) is a heterogeneous genetic heart muscle disease characterized by hypertrophy with preserved or increased ejection fraction in the absence of secondary causes. However, recent studies have demonstrated that a substantial proportion of individuals with HCM also have comorbid diabetes me...

journal_title：Science advances

authors： Dhandapany PS,Kang S,Kashyap DK,Rajagopal R,Sundaresan NR,Singh R,Thangaraj K,Jayaprakash S,Manjunath CN,Shenthar J,Lebeche D

更新日期：2021-01-06 00:00:00

abstract：:Donkeys and horses share a common ancestor dating back to about 4 million years ago. Although a high-quality genome assembly at the chromosomal level is available for the horse, current assemblies available for the donkey are limited to moderately sized scaffolds. The absence of a better-quality assembly for the donke...

journal_title：Science advances

authors： Renaud G,Petersen B,Seguin-Orlando A,Bertelsen MF,Waller A,Newton R,Paillot R,Bryant N,Vaudin M,Librado P,Orlando L

更新日期：2018-04-04 00:00:00

abstract：:In 2018-2019, New York City experienced the largest measles outbreak in the United States in nearly three decades. To identify key contributing factors, we modeled the transmission dynamics of this outbreak. Results indicate that delayed vaccination of 1- to 4-year-olds enabled the initial spread and that increased in...

journal_title：Science advances

authors： Yang W

更新日期：2020-05-27 00:00:00

abstract：:Exploration for superconductivity is one of the research frontiers in condensed matter physics. In strongly correlated electron systems, the emergence of superconductivity is often inhibited by the formation of a thermodynamically more stable magnetic/charge order. Thus, to develop the superconductivity as the thermod...

journal_title：Science advances

authors： Oike H,Kamitani M,Tokura Y,Kagawa F

更新日期：2018-10-05 00:00:00

abstract：:Difunctionalization of alkenes is a valuable and versatile chemical transformation that could quickly build complex molecules. Extensive efforts have been made, and great achievement, such as Sharpless aminohydroxylation and dihydroxylation, has been reached. However, in marked contrast to the extensive research of am...

journal_title：Science advances

authors： Yuan Y,Chen Y,Tang S,Huang Z,Lei A

更新日期：2018-08-03 00:00:00

abstract：:Metabolic reprogramming is widely considered a hallmark of cancer, and understanding metabolic dynamics described by the conversion rates or "fluxes" of metabolites can shed light onto biological processes of tumorigenesis and response to therapy. For real-time analysis of metabolic flux in intact cells or organisms, ...

journal_title：Science advances

authors： Jeong S,Eskandari R,Park SM,Alvarez J,Tee SS,Weissleder R,Kharas MG,Lee H,Keshari KR

更新日期：2017-06-16 00:00:00

abstract：:An immense demand in biomedical imaging is to develop efficient photoluminescent probes with high biocompatibility and quantum yield, as well as multiphoton absorption performance to improve penetration depth and spatial resolution. Here, iron selenide (FeSe) quantum dots (QDs) are reported to meet these criteria. The...

journal_title：Science advances

authors： Kwon J,Jun SW,Choi SI,Mao X,Kim J,Koh EK,Kim YH,Kim SK,Hwang DY,Kim CS,Lee J

更新日期：2019-12-06 00:00:00

abstract：:Organic matter burial in mangrove forests results in the removal and long-term storage of atmospheric CO2, so-called "blue carbon." However, some of this organic matter is metabolized and returned to the atmosphere as CH4. Because CH4 has a higher global warming potential than the CO2 fixed in the organic matter, it c...

journal_title：Science advances

authors： Rosentreter JA,Maher DT,Erler DV,Murray RH,Eyre BD

更新日期：2018-06-13 00:00:00

abstract：:At a time of heightened anxiety surrounding immigration, state governments have increasingly sought to manage immigrant and refugee flows. Yet the factors that influence where immigrants choose to settle after arrival remain unclear. We bring evidence to this question by analyzing population-level data for refugees re...

journal_title：Science advances

authors： Mossaad N,Ferwerda J,Lawrence D,Weinstein J,Hainmueller J

更新日期：2020-08-07 00:00:00

abstract：:The urea channel of Helicobacterpylori (HpUreI) is an ideal drug target for preventing gastric cancer but incomplete understanding of its gating mechanism has hampered development of inhibitors for the eradication of H. pylori. Here, we present the cryo-EM structures of HpUreI in closed and open conformations, both at...

journal_title：Science advances

authors： Cui Y,Zhou K,Strugatsky D,Wen Y,Sachs G,Zhou ZH,Munson K

更新日期：2019-03-20 00:00:00

abstract：:Focal adjustment and zooming are universal features of cameras and advanced optical systems. Such tuning is usually performed longitudinally along the optical axis by mechanical or electrical control of focal length. However, the recent advent of ultrathin planar lenses based on metasurfaces (metalenses), which opens ...

journal_title：Science advances

authors： She A,Zhang S,Shian S,Clarke DR,Capasso F

更新日期：2018-02-23 00:00:00

abstract：:The structural hierarchy exhibited by materials on more than one length scale can play a major part in determining bulk material properties. Understanding the hierarchical structure can lead to new materials with physical properties tailored for specific applications. We have used a combined experimental and phase-fie...

journal_title：Science advances

authors： Meher S,Aagesen LK,Carroll MC,Pollock TM,Carroll LJ

更新日期：2018-11-16 00:00:00

abstract：:Passive radiative cooling functions by reflecting the solar spectrum and emitting infrared waves in broadband or selectively. However, cooling enclosed spaces that trap heat by greenhouse effect remains a challenge. We present a Janus emitter (JET) consisting of an Ag-polydimethylsiloxane layer on micropatterned quart...

journal_title：Science advances

authors： Heo SY,Lee GJ,Kim DH,Kim YJ,Ishii S,Kim MS,Seok TJ,Lee BJ,Lee H,Song YM

更新日期：2020-09-04 00:00:00

abstract：:Synthetic aperture radar is a well-known technique for improving resolution in radio imaging. Extending these synthetic aperture techniques to the visible light domain is not straightforward because optical receivers cannot measure phase information. We propose to use macroscopic Fourier ptychography (FP) as a practic...

journal_title：Science advances

authors： Holloway J,Wu Y,Sharma MK,Cossairt O,Veeraraghavan A

更新日期：2017-04-14 00:00:00

abstract：:Half-filled Landau levels host an emergent Fermi liquid that displays instability toward pairing, culminating in a gapped even-denominator fractional quantum Hall ground state. While this pairing may be probed by tuning the polarization of carriers in competing orbital and spin degrees of freedom, sufficiently high qu...

journal_title：Science advances

authors： Falson J,Tabrea D,Zhang D,Sodemann I,Kozuka Y,Tsukazaki A,Kawasaki M,von Klitzing K,Smet JH

更新日期：2018-09-14 00:00:00

abstract：:The exceptionally long quantum coherence times of phosphorus donor nuclear spin qubits in silicon, coupled with the proven scalability of silicon-based nano-electronics, make them attractive candidates for large-scale quantum computing. However, the high threshold of topological quantum error correction can only be ca...

journal_title：Science advances

authors： Hill CD,Peretz E,Hile SJ,House MG,Fuechsle M,Rogge S,Simmons MY,Hollenberg LC

更新日期：2015-10-30 00:00:00

abstract：:We report a dual-mode organic photodetector (OPD) that has a trilayer visible light absorber/optical spacer/near-infrared (NIR) light absorber configuration. In the presence of NIR light, photocurrent is produced in the NIR light-absorbing layer due to the trap-assisted charge injection at the organic/cathode interfac...

journal_title：Science advances

authors： Lan Z,Lei Y,Chan WKE,Chen S,Luo D,Zhu F

更新日期：2020-01-31 00:00:00

abstract：:V1-ATPase is an ATP-driven rotary motor that is composed of a ring-shaped A3B3 complex and a central DF shaft. The nucleotide-free A3B3 complex of Enterococcus hirae, composed of three identical A1B1 heterodimers, showed a unique asymmetrical structure, probably due to the strong binding of the N-terminal barrel domai...

journal_title：Science advances

authors： Maruyama S,Suzuki K,Imamura M,Sasaki H,Matsunami H,Mizutani K,Saito Y,Imai FL,Ishizuka-Katsura Y,Kimura-Someya T,Shirouzu M,Uchihashi T,Ando T,Yamato I,Murata T

更新日期：2019-01-30 00:00:00

abstract：:RNA interference (RNAi) technology can specifically silence the expression of a target gene and has emerged as a promising therapeutic method to treat cancer. In the present study, we showed that natural halloysite nanotube (HNT)-assisted delivery of an active small interfering RNA (siRNA) targeting receptor-interacti...

journal_title：Science advances

authors： Liu J,Zhang Y,Zeng Q,Zeng H,Liu X,Wu P,Xie H,He L,Long Z,Lu X,Xiao M,Zhu Y,Bo H,Cao K

更新日期：2019-09-25 00:00:00

abstract：:Coordinatively unsaturated (CUS) iron sites are highly active in catalytic oxidation reactions; however, maintaining the CUS structure of iron during heterogeneous catalytic reactions is a great challenge. Here, we report a strategy to stabilize single-atom CUS iron sites by embedding highly dispersed FeN4 centers in ...

journal_title：Science advances

authors： Deng D,Chen X,Yu L,Wu X,Liu Q,Liu Y,Yang H,Tian H,Hu Y,Du P,Si R,Wang J,Cui X,Li H,Xiao J,Xu T,Deng J,Yang F,Duchesne PN,Zhang P,Zhou J,Sun L,Li J,Pan X,Bao X

更新日期：2015-12-04 00:00:00

abstract：:The progression in the hair follicle cycle from the telogen to the anagen phase is the key to regulating hair regrowth. Dermal papilla (DP) cells support hair growth and regulate the hair cycle. However, they gradually lose key inductive properties upon culture. DP cells can partially restore their capacity to promote...

journal_title：Science advances

authors： Hu S,Li Z,Lutz H,Huang K,Su T,Cores J,Dinh PC,Cheng K

更新日期：2020-07-24 00:00:00

abstract：:Gravel-bed river floodplains in mountain landscapes disproportionately concentrate diverse habitats, nutrient cycling, productivity of biota, and species interactions. Although stream ecologists know that river channel and floodplain habitats used by aquatic organisms are maintained by hydrologic regimes that mobilize...

journal_title：Science advances

authors： Hauer FR,Locke H,Dreitz VJ,Hebblewhite M,Lowe WH,Muhlfeld CC,Nelson CR,Proctor MF,Rood SB

更新日期：2016-06-24 00:00:00

abstract：:Students from underrepresented groups start college with the same level of interest in STEM majors as their peers, but leave STEM at higher rates. We tested the hypothesis that low grades in general chemistry contribute to this "weeding," using records from 25,768 students. In the first course of a general chemistry s...

journal_title：Science advances

authors： Harris RB,Mack MR,Bryant J,Theobald EJ,Freeman S

更新日期：2020-06-10 00:00:00