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New spectrum of the neurologic consequences of Zika.

Abstract：

:Zika virus infection represents a new neuropathological agent with association to a wide spectrum of neurological complications: a) Congenital Zika Syndrome by affecting the neural stem cells of the human fetal brain; b) Guillain-Barré Syndrome by an autoimmune response against peripheral myelin and/or axonal components or probable direct inflammatory reaction; c) Encephalitis/meningoencephalitis and myelitis by a direct viral inflammatory process on the central nervous system; d) Sensory neuropathy by infecting directly the peripheral neurons and causing substantial cell death and pathogenic transcriptional dysregulation; e) Acute Disseminated Encephalomyelitis and optic neuropathy; f) Seizures and Epilepsy and g) childhood arterial ischemic stroke by probable inflammatory reaction and endothelial injury.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Medina MT,Medina-Montoya M

doi

10.1016/j.jns.2017.10.046

subject

Has Abstract

pub_date

2017-12-15 00:00:00

pages

214-215

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(17)34426-X

journal_volume

383

pub_type

社论

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