Abstract:
:Superficial spreading melanoma (SSM) is the most common type of melanoma. Large, population-based studies analyzing the incidence and survival of SSM are limited. This retrospective study was designed to evaluate demographic factors influencing the incidence and survival of SSM using a national population-based database. The United States National Cancer Institute's Surveillance, Epidemiology, and End Results registry was used to calculate incidence and disease-specific survival trends for SSM between 1973 and 2012. Patient data were stratified according to age, sex, race, ulceration, thickness, and stage. Of 97 702 patients, 52.66% were men, 94.93% were white, and 38.92% had a primary lesion on the trunk. The overall incidence is 5.987/100 000 and is increasing with an annual percentage change (APC) of 1.42%. Incidence increases with age, peaking at 70-79 years. Men (6.68/100 00, APC: 1.78) had a significantly higher incidence than women (5.565/100 000, APC: 1.10). A total of 79.16% of SSM are less than or equal to 1 mm and 92.32% are nonulcerated. The overall 5-year survival is 95.30% and is increasing steadily. Women (hazard ratio: 0.54), 'other' races (hazard ratio: 0.30), those with local disease, those with thin tumors, and those without ulceration had higher survival than their counterparts (P<0.0001). The incidence of this predominantly thin melanoma subtype is on the rise, creating enhanced concern. Primary and secondary prevention techniques should consider the mortality associated with thin melanoma.
journal_name
Melanoma Resjournal_title
Melanoma researchauthors
Singh P,Kim HJ,Schwartz RAdoi
10.1097/CMR.0000000000000245subject
Has Abstractpub_date
2016-08-01 00:00:00pages
395-400issue
4eissn
0960-8931issn
1473-5636journal_volume
26pub_type
杂志文章abstract::The aim of our study was to evaluate the clinical and morphological features of primary malignant melanomas of the urinary bladder. We obtained information on five such cases from three different institutions. These were three men and two women between 52 and 76 years of age. Three tumors presented with hematuria, one...
journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/CMR.0000000000000300
更新日期:2016-12-01 00:00:00
abstract::Malignant melanoma is not only one of the most aggressive and lethal types of neoplasm, but its incidence in the general population is currently increasing at an alarming pace. It is interesting that most melanomas retain many of their characteristics of differentiation, including a dendritic nature and the production...
journal_title:Melanoma research
pub_type: 杂志文章,评审
doi:
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/CMR.0b013e32835c7e68
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-200008000-00007
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journal_title:Melanoma research
pub_type: 杂志文章,评审
doi:10.1097/CMR.0b013e32833faf6a
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journal_title:Melanoma research
pub_type: 杂志文章
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journal_title:Melanoma research
pub_type: 杂志文章
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-199211000-00002
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journal_title:Melanoma research
pub_type: 杂志文章
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journal_title:Melanoma research
pub_type: 杂志文章,评审
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-199808000-00008
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/CMR.0000000000000456
更新日期:2018-08-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-199504000-00009
更新日期:1995-04-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:
更新日期:2000-02-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-200402000-00004
更新日期:2004-02-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/CMR.0b013e32835fb524
更新日期:2013-06-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-200308000-00003
更新日期:2003-08-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-200404000-00006
更新日期:2004-04-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-200202000-00010
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-199908000-00010
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pub_type: 杂志文章,多中心研究
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journal_title:Melanoma research
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journal_title:Melanoma research
pub_type: 杂志文章
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/CMR.0b013e32832a1e41
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-199904000-00010
更新日期:1999-04-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
doi:10.1097/00008390-200012000-00010
更新日期:2000-12-01 00:00:00
abstract::We studied the efficacy, tolerability and clinical courses of dabrafenib in patients with metastatic melanoma who were ineligible for enrolment into a clinical trial. Between July 2011 and May 2013, patients with unresectable stage III or stage IV, V600-mutated metastatic melanoma who were not eligible for inclusion i...
journal_title:Melanoma research
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更新日期:2014-04-01 00:00:00
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journal_title:Melanoma research
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doi:10.1097/00008390-200302000-00014
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journal_title:Melanoma research
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更新日期:2016-12-01 00:00:00
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journal_title:Melanoma research
pub_type: 杂志文章
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