Abstract：
PURPOSE:Knowledge about changes in exposure to toxic metals over time remains very sparse, in particular for children, the most vulnerable group. Here, we assessed whether a reduction in environmental pollution with cadmium (Cd) and mercury (Hg) caused a change in exposure over time. In total, 1257 children (age 4-9) in two towns in Sweden were sampled once in 1986-2013. Blood concentrations of Cd (b-Cd; n=1120) and Hg (b-Hg; n=560) were determined. RESULTS:The median b-Cd was 0.10 (geometric mean 0.10; range 0.010-0.61) μg/L and b-Hg was 0.91 (geometric mean 0.83; range 0.021-8.2) μg/L. Children living close to a smelter had higher b-Cd and b-Hg than those in urban and rural areas. There was no sex difference in b-Cd or b-Hg, and b-Cd and b-Hg showed no significant accumulation by age. b-Cd decreased only slightly (0.7% per year, p<0.001) over the study period. In contrast, b-Hg did show a clear decrease over the study period (3% per year, p<0.001). CONCLUSIONS:The exposure to Cd was very low but still might increase the risk of disease later in life. Moreover, b-Cd only showed a minor decrease, indicating that Cd pollution should be further restricted. b-Hg was relatively low and decreasing, probably because of reduced use of dental amalgam and lower Hg intake from fish. The b-Cd and b-Hg levels decreased much less than the levels of lead in the blood as previously found in the same children.
journal_name
Environ Resjournal_title
Environmental researchauthors
Lundh T,Axmon A,Skerfving S,Broberg Kdoi
10.1016/j.envres.2016.02.016subject
Has Abstractpub_date
2016-10-01 00:00:00pages
600-605eissn
0013-9351issn
1096-0953pii
S0013-9351(16)30058-5journal_volume
150pub_type
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