Applications of spectroscopy in diagnosis, staging, and treatment of urologic malignancies.

Abstract:

PURPOSE OF REVIEW:To review the scientific literature on clinical applications of spectroscopy within urologic oncology. Specifically, we address the role of spectroscopy as a novel intraoperative or intraprocedural modality for the management of urothelial carcinoma, renal cell carcinoma, and prostate adenocarcinoma. RECENT FINDINGS:Recent studies have demonstrated that spectroscopy models, suitable for translation to in-vivo clinical use, can differentiate between benign parenchyma and malignant tissue for urothelial carcinoma, renal cell carcinoma, and prostate adenocarcinoma. Recent work has also established spectroscopy as a feasible modality to detect biologically aggressive high-risk disease and classify natural biomarkers. SUMMARY:Spectroscopy has the ability to objectively diagnose and stage malignancies in real time without tissue or cellular disruption. In the future, additional in-vivo studies will be needed to demonstrate that current models remain robust under physiological conditions.

journal_name

Curr Opin Urol

authors

Seltz LM,Herrell SD

doi

10.1097/MOU.0000000000000281

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

259-63

issue

3

eissn

0963-0643

issn

1473-6586

journal_volume

26

pub_type

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