Abstract:
:Skin-picking disorder (SPD) is a common mental disorder characterized by recurrent and excessive picking of dermatological irregularities. Different disorder models have been developed to explain this behavior, but empirical evidence is still scarce. One model (the disgust-related disease avoidance model) suggests that SPD might be understood as pathological grooming elicited by skin imperfections that singal possible infection. Twenty-five women with SPD and 19 matched controls viewed and rated images depicting skin irregularities and smooth skin during functional magnetic resonance imaging. The participants did not engage in picking behavior. Relative to controls, SPD patients reported more disgust and urge to pick when looking at skin irregularities. This was accompanied by greater activation in the insula and amygdala, and stronger insula-putamen coupling. Disgust feelings elicited by viewing skin irregularities were positively correlated with activation of the insula and the putamen, in the clinical group. On personality questionnaires, the SPD patients reported elevated self-loathing and problems in regulating their disgust feelings. The current study provides first evidence for altered disgust processing in SPD patients.
journal_name
Brain Imaging Behavjournal_title
Brain imaging and behaviorauthors
Schienle A,Übel S,Wabnegger Adoi
10.1007/s11682-017-9792-xsubject
Has Abstractpub_date
2018-10-01 00:00:00pages
1504-1512issue
5eissn
1931-7557issn
1931-7565pii
10.1007/s11682-017-9792-xjournal_volume
12pub_type
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journal_title:Brain imaging and behavior
pub_type: 杂志文章,随机对照试验
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journal_title:Brain imaging and behavior
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journal_title:Brain imaging and behavior
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更新日期:2012-03-01 00:00:00
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journal_title:Brain imaging and behavior
pub_type: 杂志文章,多中心研究
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更新日期:2018-06-01 00:00:00
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journal_title:Brain imaging and behavior
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journal_title:Brain imaging and behavior
pub_type: 杂志文章,评审
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更新日期:2014-09-01 00:00:00
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更新日期:2012-06-01 00:00:00
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更新日期:2019-12-01 00:00:00
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journal_title:Brain imaging and behavior
pub_type: 杂志文章
doi:10.1007/s11682-015-9425-1
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