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Paternal exposure to antirheumatic drugs-What physicians should know: Review of the literature.

Abstract：

:Reproduction capacity and long-term preserved hormonal function are important aspects with big impacts on patients' quality of life. Updated information on the interaction between drug therapy and reproductive function is essential when discussing family planning with patients. Currently, limited data is published regarding paternal exposure to different medications. Thus, it may be a challenge for the practitioner to choose the right therapy for a young male patient. Therefore we reviewed the literature, for effects of antirheumatic drugs on male gonadal function with a focus on spermatogenesis and offspring.

journal_name

Semin Arthritis Rheum

journal_title

Seminars in arthritis and rheumatism

authors

Micu MC,Ostensen M,Villiger PM,Micu R,Ionescu R

doi

10.1016/j.semarthrit.2018.01.006

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

343-355

issue

2

eissn

0049-0172

issn

1532-866X

pii

S0049-0172(17)30747-3

journal_volume

48

pub_type

杂志文章,评审

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