Pulmonary disease during the treatment of rheumatoid arthritis with low dose pulse methotrexate.

Abstract:

:Methotrexate therapy has been effective in the treatment of RA with short term experience suggesting little serious adverse reactions. Our review of 168 patients receiving methotrexate has identified nine patients with probable or possible methotrexate-induced pulmonary toxicity, giving a prevalence of 5% and an incidence of 3.9 per 100 patients per year. No clinical or laboratory features showed an association that could potentially predict the development of pulmonary disease. All patients experienced complete recovery with supportive care and/or corticosteroid therapy. Clinical monitoring for this complication is warranted in all patients receiving long term methotrexate therapy for RA.

journal_name

Semin Arthritis Rheum

authors

Carson CW,Cannon GW,Egger MJ,Ward JR,Clegg DO

doi

10.1016/0049-0172(87)90021-7

subject

Has Abstract

pub_date

1987-02-01 00:00:00

pages

186-95

issue

3

eissn

0049-0172

issn

1532-866X

pii

0049-0172(87)90021-7

journal_volume

16

pub_type

杂志文章
  • Incidence of COVID-19 in a cohort of adult and paediatric patients with rheumatic diseases treated with targeted biologic and synthetic disease-modifying anti-rheumatic drugs.

    abstract:Objectives:To investigate the incidence of COVID-19 in a cohort of adult and paediatric patients with rheumatic diseases receiving targeted biologic and synthetic disease modifying anti-rheumatic drugs (tDMARDs) and to explore the possible effect of these treatments in the clinical expression of COVID-19. Methods:A cr...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/j.semarthrit.2020.05.001

    authors: Michelena X,Borrell H,López-Corbeto M,López-Lasanta M,Moreno E,Pascual-Pastor M,Erra A,Serrat M,Espartal E,Antón S,Añez GA,Caparrós-Ruiz R,Pluma A,Trallero-Araguás E,Barceló-Bru M,Almirall M,De Agustín JJ,Lladós J,Jul

    更新日期:2020-08-01 00:00:00

  • The effects of intraarticular administration of hyaluronan in a model of early osteoarthritis in sheep. I. Gait analysis and radiological and morphological studies.

    abstract::Using a model of early osteoarthritis (OA) induced in ovine joints by medial meniscectomy, the intraarticular effects of two hyaluronic acid (HA) preparations (AHA and DHA) were investigated. DHA was an HA preparation with an average molecular weight (MW) of approximately 2.0 x 10(6) d, and AHA had a MW of approximate...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/s0049-0172(10)80016-2

    authors: Ghosh P,Read R,Armstrong S,Wilson D,Marshall R,McNair P

    更新日期:1993-06-01 00:00:00

  • Neurological complications of connective tissue and other "collagen-vascular" diseases.

    abstract::A variety of neurological complications may occur in the various connective tissue and "collagen-vascular" diseases. Most of these complications are due to vasculitis affecting various sites in the central or peripheral nervous system. While the evidence for definitive vasculitis in SLE is not strong, small vessel dam...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/0049-0172(81)90100-1

    authors: Cohen SB,Hurd ER

    更新日期:1981-08-01 00:00:00

  • An outcome survey of 43 patients with Budd-Chiari syndrome due to Behçet's syndrome followed up at a single, dedicated center.

    abstract:BACKGROUND:Behçet's syndrome (BS) is a well-recognized cause of Budd-Chiari syndrome (BCS); however, information about its clinical characteristics and outcome is limited. METHODS:We reviewed the records of about 9000 patients with BS registered at the multidisciplinary Behçet's syndrome outpatient clinic at Cerrahpas...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/j.semarthrit.2014.10.014

    authors: Seyahi E,Caglar E,Ugurlu S,Kantarci F,Hamuryudan V,Sonsuz A,Melikoglu M,Yurdakul S,Yazici H

    更新日期:2015-04-01 00:00:00

  • Pneumocystis jirovecii pneumonia (PJP) prophylaxis patterns among patients with rheumatic diseases receiving high-risk immunosuppressant drugs.

    abstract:INTRODUCTION/OBJECTIVES:Pneumocystis jirovecii pneumonia (PJP) is a rare but potentially fatal opportunistic infection; however, consensus varies around which conditions or medications confer a level of risk sufficient to justify antibiotic prophylaxis for PJP. We used electronic health record (EHR) data to assess the ...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/j.semarthrit.2018.10.018

    authors: Schmajuk G,Jafri K,Evans M,Shiboski S,Gianfrancesco M,Izadi Z,Patterson SL,Aggarwal I,Sarkar U,Dudley RA,Yazdany J

    更新日期:2019-06-01 00:00:00

  • Clinical trial development for biosimilars.

    abstract:OBJECTIVES:Discuss issues regarding clinical trial design for the development of biosimilars in the European Union and the United States, with special focus on monoclonal antibodies used in the treatment of inflammatory diseases. METHODS:A search of the Internet as well as PubMed was conducted through June 2014 for in...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章,评审

    doi:10.1016/j.semarthrit.2015.04.002

    authors: Alten R,Cronstein BN

    更新日期:2015-06-01 00:00:00

  • Polyarteritis nodosa presenting as polymyositis.

    abstract:BACKGROUND:Skeletal muscle involvement has been well documented in patients with polyarteritis nodosa (PAN), and symptoms referable to skeletal muscle are not uncommon. However, polymyositis as a mode of presentation of PAN is uncommon. This unusual presentation of PAN has been reported only once previously in the Engl...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1053/sarh.2002.32549

    authors: Plumley SG,Rubio R,Alasfar S,Jasin HE

    更新日期:2002-06-01 00:00:00

  • Tubulointerstitial nephritis and uveitis syndrome in Southern Spain.

    abstract:OBJECTIVE:To examine immunogenetic and clinical features in a series of patients with the idiopathic tubulointerstitial nephritis and uveitis (TINU) syndrome diagnosed at the single referral hospital for a defined population in Southern Spain. PATIENTS AND METHODS:Retrospective study of the case records of all patient...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1053/sarh.2002.33718

    authors: Sanchez-Burson J,Garcia-Porrua C,Montero-Granados R,Gonzalez-Escribano F,Gonzalez-Gay MA

    更新日期:2002-10-01 00:00:00

  • Physical activity interventions among adults with arthritis: meta-analysis of outcomes.

    abstract:OBJECTIVE:Due to reduced physical activity, adults with arthritis experience significant disability and comorbidities including cardiovascular disease. This meta-analytic review integrates results from primary research studies testing interventions to increase physical activity in arthritis patients. METHODS:Extensive...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.semarthrit.2007.07.006

    authors: Conn VS,Hafdahl AR,Minor MA,Nielsen PJ

    更新日期:2008-04-01 00:00:00

  • A cohort study reveals myocarditis to be a rare and life-threatening presentation of large vessel vasculitis.

    abstract:BACKGROUND:The predominant forms of adult large vessel vasculitis (LVV) are giant cell arteritis (GCA) and Takayasu arteritis (TA). Cardiac involvement in LVV is a cause of morbidity and mortality, particularly in TA. Cardiac failure is most commonly secondary to uncontrolled arterial hypertension or myocardial ischaem...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/j.semarthrit.2017.03.023

    authors: Bechman K,Gopalan D,Nihoyannopoulos P,Mason JC

    更新日期:2017-10-01 00:00:00

  • Patients with rheumatoid arthritis undergoing surgery: how should we deal with antirheumatic treatment?

    abstract:OBJECTIVES:To review published data on the perioperative management of antirheumatic treatment and perioperative outcome in patients with rheumatoid arthritis (RA). METHODS:The review is based on a MEDLINE (PubMed) search of the English-language literature from 1965 to 2005, using the index keywords "rheumatoid arthri...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章,评审

    doi:10.1016/j.semarthrit.2006.10.003

    authors: Pieringer H,Stuby U,Biesenbach G

    更新日期:2007-04-01 00:00:00

  • Metabolism as a key regulator in the pathogenesis of systemic lupus erythematosus.

    abstract::In the middle of the 20th century, biologists focused on investigating the mechanism of gene regulation and signal transduction in cells, which led to the concept that metabolites were products of gene expression and signal transduction pathways. In the 1920s, the importance of cellular metabolism was shown in the War...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章,评审

    doi:10.1016/j.semarthrit.2019.04.006

    authors: Takeshima Y,Iwasaki Y,Fujio K,Yamamoto K

    更新日期:2019-06-01 00:00:00

  • Early life body size, growth and risks of systemic lupus erythematosus - A large Danish observational cohort study.

    abstract:OBJECTIVES:Adult obesity may increase the risks of systemic lupus erythematosus (SLE), and there are genetic links between adult height and SLE. Thus, it is plausible that size earlier in life may be important in the aetiology of SLE as well. We investigated whether birthweight, childhood body mass index (BMI; [kg/m2])...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/j.semarthrit.2020.01.011

    authors: Thomas PE,Jensen BW,Sørensen KK,Jacobsen S,Aarestrup J,Baker JL

    更新日期:2020-12-01 00:00:00

  • Ultrasound-defined remission and active disease in rheumatoid arthritis: association with clinical and serologic parameters.

    abstract:OBJECTIVE:To assess the association of clinical and/or serological parameters with ultrasound-defined disease activity in rheumatoid arthritis (RA). METHODS:Retrospective analysis of 149 consecutive RA patients routinely assessed by sonography of the wrists, metacarpo-phalangeal, and proximal interphalangeal joints. S...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/j.semarthrit.2011.09.005

    authors: Dejaco C,Duftner C,Wipfler-Freissmuth E,Weiss H,Graninger WB,Schirmer M

    更新日期:2012-06-01 00:00:00

  • Transition to adult rheumatology care is necessary to maintain DMARD therapy in young people with juvenile idiopathic arthritis.

    abstract:OBJECTIVE:To evaluate the outpatient health service utilisation of young people (YP) with juvenile idiopathic arthritis (JIA) during transfer from paediatric to adult care in Germany. METHODS:Based on claims data of a large German statutory health fund (BARMER GEK) we conducted a cohort study of 2008-2014. Insured YP ...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/j.semarthrit.2017.05.003

    authors: Luque Ramos A,Hoffmann F,Albrecht K,Klotsche J,Zink A,Minden K

    更新日期:2017-10-01 00:00:00

  • Spontaneous pyogenic facet joint infection.

    abstract:OBJECTIVE:To analyze the clinical features, approaches to management, and outcome of spontaneous pyogenic facet joint infection (PFJI) in adults. PATIENTS AND METHODS:Case series of 10 adults with microbiologically proven PFJI diagnosed during a 10-year period in a teaching hospital, plus a review of 32 additional cas...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/j.semarthrit.2005.09.003

    authors: Narváez J,Nolla JM,Narváez JA,Martinez-Carnicero L,De Lama E,Gómez-Vaquero C,Murillo O,Valverde J,Ariza J

    更新日期:2006-04-01 00:00:00

  • Risk profiling for a refractory course of giant cell arteritis: The importance of age and body weight: "Risk profiling for GC resistance in GCA".

    abstract:BACKGROUND:Giant cell arteritis (GCA) is a disease that relapses often, and some patients run a refractory course. Although prompt recognition of resistant GCA is a major issue, there is no well-recognized, baseline risk factor for poor response to glucocorticoid (GC) treatment. METHODS:We included all patients consec...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/j.semarthrit.2020.09.009

    authors: Liozon E,Dumonteil S,Parreau S,Gondran G,Bezanahary H,Palat S,Ly KH,Fauchais AL

    更新日期:2020-12-01 00:00:00

  • Therapeutic options for refractory massive pleural effusion in systemic lupus erythematosus: a case study and review of the literature.

    abstract:OBJECTIVES:Massive refractory pleural effusions are uncommon in patients with systemic lupus erythematosus. Describing such a patient, the literature was reviewed to report the various therapeutic options in such cases. METHODS:MEDLINE search using the terms "lupus" and "pleural effusion," inclusion of cases with refr...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章,评审

    doi:10.1016/j.semarthrit.2004.11.003

    authors: Breuer GS,Deeb M,Fisher D,Nesher G

    更新日期:2005-04-01 00:00:00

  • Trigeminal neuralgia in systemic sclerosis.

    abstract:OBJECTIVES:Although trigeminal neuralgia (TN) has been associated with systemic sclerosis (SSc), there is a paucity of evidence and pathophysiological processes remain unknown. We undertook a nested case-control study to identify associations between TN and SSc in a large multi-centered cohort and identify possible pat...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/j.semarthrit.2021.01.001

    authors: Maltez N,Choi MY,Troyanov Y,Wang M,Jantz M,Fritzler MJ,Baron M,Hudson M,Canadian Scleroderma Research Group.

    更新日期:2021-01-07 00:00:00

  • Risk of mortality, fatal infection, and fatal malignancy related to use of anti-tumor necrosis factor-α biologics by rheumatoid arthritis patients.

    abstract:OBJECTIVE:To estimate rates of all-cause mortality, fatal infection, and fatal malignancy in rheumatoid arthritis (RA) patients treated with anti-tumor necrosis factor-α (anti-TNF) biologics. METHODS:A retrospective cohort study of RA patients initiating therapy with adalimumab, etanercept, or infliximab from January ...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/j.semarthrit.2012.05.004

    authors: Thyagarajan V,Norman H,Alexander KA,Napalkov P,Enger C

    更新日期:2012-12-01 00:00:00

  • Malignancy in psoriatic disease: Results from prospective longitudinal cohorts.

    abstract:OBJECTIVES:To estimate the prevalence and incidence of malignancy and its types in psoriatic arthritis (PsA) and psoriasis without arthritis (PsC) patients, in comparison to the general population, and to identify the predictive factors for developing cancer in psoriatic disease (PsD). METHODS:PsA patients followed pr...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/j.semarthrit.2020.12.008

    authors: Polachek A,Muntyanu A,Lee KA,Ye JY,Chandran V,Cook RJ,Gladman DD

    更新日期:2020-12-24 00:00:00

  • Role of collagen hydrolysate in bone and joint disease.

    abstract:OBJECTIVES:To review the current status of collagen hydrolysate in the treatment of osteoarthritis and osteoporosis. METHODS:Review of past and current literature relative to collagen hydrolysate metabolism, and assessment of clinical investigations of therapeutic trials in osteoarthritis and osteoporosis. RESULTS:Hy...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1053/sarh.2000.9622

    authors: Moskowitz RW

    更新日期:2000-10-01 00:00:00

  • Clinical characteristics and risk factors of infection in patients with systemic lupus erythematosus: A systematic review and meta-analysis of observational studies.

    abstract:OBJECTIVE:Infection is one of the major causes of morbidity and mortality in systemic lupus erythematosus (SLE) patients. We conducted a systematic review and meta-analysis to investigate the clinical characteristics and risk factors of infection in SLE by comparing demographic factors, laboratory data, clinical featur...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章,评审

    doi:10.1016/j.semarthrit.2020.06.004

    authors: Yuan Q,Xing X,Lu Z,Li X

    更新日期:2020-10-01 00:00:00

  • The pathobiology of osteoarthritis and the rationale for the use of pentosan polysulfate for its treatment.

    abstract:OBJECTIVES:Structure-modifying osteoarthritis (OA) drugs (SMOADs) may be defined as agents that reverse, retard, or stabilize the underlying pathology of OA, thereby providing symptomatic relief in the long-term. The objective of this review was to evaluate the literature on sodium pentosan polysulfate (NaPPS) and calc...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章,评审

    doi:10.1016/s0049-0172(99)80021-3

    authors: Ghosh P

    更新日期:1999-02-01 00:00:00

  • Hepatitis C virus infection and autoimmunity.

    abstract::Hepatitis C virus (HCV) infection has been associated with a plethora of immune and autoimmune perturbations. We review serological and clinical autoimmune manifestations associated with HCV infection, discuss treatment regimens for HCV-related autoimmune diseases, and present a framework for understanding HCV-associa...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章,评审

    doi:10.1016/s0049-0172(97)80005-4

    authors: McMurray RW,Elbourne K

    更新日期:1997-02-01 00:00:00

  • Sparing effect of hemiplegia on skin fibrosis and microvascular involvement: reports of two cases of systemic sclerosis and review of the literature.

    abstract:OBJECTIVES:The sparing effect of hemiplegia in rheumatic diseases has been described, but reports on systemic sclerosis (SSc)-spectrum disorders are unusual. SSc-spectrum disorders are complex diseases of unknown origin characterized by multisystem involvement, skin and organ fibrosis, microvascular alterations, and im...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章,评审

    doi:10.1016/j.semarthrit.2014.10.011

    authors: Ughi N,Hervey SA,Gualtierotti R,Silvana Z,Herrick AL,Ingegnoli F,Meroni P

    更新日期:2015-04-01 00:00:00

  • Mechanoflammation in osteoarthritis pathogenesis.

    abstract::Mechanical injury is the most important risk factor in osteoarthritis (OA) development. Although once considered a passive disease of mechanical attrition, injury drives active mechanosensitive intracellular signalling which affects the structural and symptomatic course of disease. Mechanosensitive signalling in carti...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章,评审

    doi:10.1016/j.semarthrit.2019.09.018

    authors: Vincent TL

    更新日期:2019-12-01 00:00:00

  • Development of biosimilars.

    abstract:OBJECTIVE:To provide an overview of the underlying scientific principles and standards for developing a biosimilar product. METHODS:An Internet-based literature search through June 2015 was performed for information related to biosimilar manufacturing and development, including a review of regulatory guidelines and re...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章,评审

    doi:10.1016/j.semarthrit.2016.01.002

    authors: Al-Sabbagh A,Olech E,McClellan JE,Kirchhoff CF

    更新日期:2016-04-01 00:00:00

  • Anti-TNF-α therapy in refractory uveitis associated with sarcoidosis: Multicenter study of 17 patients.

    abstract:OBJECTIVES:To assess anti-TNF-α therapy response in uveitis associated with sarcoidosis refractory to conventional immunosuppressive therapy. METHODS:Open-label, multicenter, retrospective study on patients with sarcoid uveitis who underwent anti-TNF-α therapy because of inadequate response to conventional therapy inc...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.semarthrit.2015.05.010

    authors: Riancho-Zarrabeitia L,Calvo-Río V,Blanco R,Mesquida M,Adan AM,Herreras JM,Aparicio Á,Peiteado-Lopez D,Cordero-Coma M,García Serrano JL,Ortego-Centeno N,Maíz O,Blanco A,Sánchez-Bursón J,González-Suárez S,Fonollosa A,Santos

    更新日期:2015-12-01 00:00:00

  • Lymphopenia as a risk factor for neurologic involvement and organ damage accrual in patients with systemic lupus erythematosus: A multi-center observational study.

    abstract:OBJECTIVE:Detailed analysis of hematological manifestations (HM) in systemic lupus erythematosus (SLE) are limited and their clinical impact on disease remain obscure. Here, we aimed to decipher factors associated with different hematological abnormalities in SLE patients and to assess their impact on disease related o...

    journal_title:Seminars in arthritis and rheumatism

    pub_type: 杂志文章

    doi:10.1016/j.semarthrit.2020.02.020

    authors: Yavuz S,Cansu DU,Nikolopoulos D,Crisafulli F,Antunes AM,Adamichou C,Reid S,Stagnaro C,Andreoli L,Tincani A,Moraes-Fontes MF,Mosca M,Leonard D,Jönsen A,Bengtsson A,Svenungsson E,Gunnarsson I,Dahlqvist SR,Sjöwall C,Be

    更新日期:2020-12-01 00:00:00