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Scientific evidence of the therapeutic effects of dead sea treatments: a systematic review.

Abstract：

OBJECTIVES:The Dead Sea, the deepest and most saline lake on earth, has been known from biblical times for its healing properties. The aim of this systematic review was to present critically the level of evidence for the claims of therapeutic effects of Dead Sea treatments in several rheumatologic diseases and psoriasis as well as to review these treatments' safety. METHODS:All articles cited in MEDLINE under the query, "Dead Sea," were reviewed. RESULTS:We found bona fide evidence that Dead Sea treatments are especially effective in psoriasis due to both the special characteristics of solar ultraviolet radiation in the Dead Sea and the Dead Sea water balneotherapy. Dead Sea mud and Dead Sea balneotherapy have been found to be beneficial in rheumatologic diseases, including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and knee osteoarthritis. In the safety analysis, we found no evidence for an increase in skin neoplasia, although skin actinic damage seems to be increased in patients treated in the Dead Sea. Dead Sea treatments do not lead to worsening of blood pressure. Substantial ingestion of Dead Sea water (generally in unusual near-drowning cases) is toxic and can result in cardiac rhythm disturbances because of electrolyte concentration abnormalities. Laboratory analysis of Dead Sea mud did not reveal mineral concentrations that could represent a health concern for their intended use. CONCLUSIONS:Dead Sea treatments are beneficial in several rheumatologic diseases and psoriasis and have a good safety profile.

journal_name

Semin Arthritis Rheum

journal_title

Seminars in arthritis and rheumatism

authors

Katz U,Shoenfeld Y,Zakin V,Sherer Y,Sukenik S

doi

10.1016/j.semarthrit.2012.02.006

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

186-200

issue

2

eissn

0049-0172

issn

1532-866X

pii

S0049-0172(12)00030-3

journal_volume

42

pub_type

杂志文章,评审

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