Genetic mapping of the mouse c-fms proto-oncogene to chromosome 18.


:Chinese hamster X mouse somatic cell hybrids were analyzed by Southern blot hybridization with a probe specific for the cellular c-fms proto-oncogene. Results demonstrate that Fms, the genetic locus containing this sequence, maps to mouse chromosome 18. Mouse Fms is thus not linked to the same set of genes involved in growth regulation that human FMS is linked to.


J Virol


Journal of virology


Hoggan MD,Halden NF,Buckler CE,Kozak CA




Has Abstract


1988-03-01 00:00:00












  • Phosphorylation of the human T-cell leukemia virus type 1 transactivator tax on adjacent serine residues is critical for tax activation.

    abstract::The Tax transactivator protein of human T-cell leukemia virus type 1 (HTLV-1) plays a central role in the activation of viral gene expression. In addition, Tax is capable of activating the expression of specific cellular genes and is involved in the transformation of T-lymphocytes resulting in the development of adult...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Bex F,Murphy K,Wattiez R,Burny A,Gaynor RB

    更新日期:1999-01-01 00:00:00

  • Protein synthesis in Newcastle disease virus-infected chicken embryo cells.

    abstract::A double-isotopic label difference analysis of polyacrylamide gels has been used to distinguish between cellular and viral protein accumulation in infected cells and to quantify the kinetics of accumulation of viral polypeptides. This technique, coupled with the determination of total radioactive amino acid incorporat...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Hightower LE,Bratt MA

    更新日期:1974-04-01 00:00:00

  • Sindbis virus proteins nsP1 and nsP2 contain homology to nonstructural proteins from several RNA plant viruses.

    abstract::Although the genetic organization of tobacco mosaic virus (TMV) differs considerably from that of the tripartite viruses (alfalfa mosaic virus [AlMV] and brome mosaic virus [BMV]), all of these RNA plant viruses share three domains of homology among their nonstructural proteins. One such domain, common to the AlMV and...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Ahlquist P,Strauss EG,Rice CM,Strauss JH,Haseloff J,Zimmern D

    更新日期:1985-02-01 00:00:00

  • Two Pioneer Transcription Factors, Krüppel-Like Transcription Factor 4 and Glucocorticoid Receptor, Cooperatively Transactivate the Bovine Herpesvirus 1 ICP0 Early Promoter and Stimulate Productive Infection.

    abstract::An important site for bovine herpesvirus 1 (BoHV-1) latency is sensory neurons within trigeminal ganglia (TG). The synthetic corticosteroid dexamethasone consistently induces BoHV-1 reactivation from latency. Expression of four Krüppel-like transcription factors (KLF), i.e., KLF4, KLF6, PLZF (promyelocytic leukemia zi...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: El-Mayet FS,Sawant L,Thunuguntla P,Zhao J,Jones C

    更新日期:2020-01-31 00:00:00

  • The reverse transcriptase of the Tf1 retrotransposon has a specific novel activity for generating the RNA self-primer that is functional in cDNA synthesis.

    abstract::The Tf1 retrotransposon of Schizosaccharomyces pombe represents a group of eukaryotic long terminal repeat (LTR) retroelements that, based on their sequences, were predicted to use an RNA self-primer for initiating reverse transcription while synthesizing the negative-sense DNA strand. This feature is substantially di...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Hizi A

    更新日期:2008-11-01 00:00:00

  • Human respiratory coronavirus OC43: genetic stability and neuroinvasion.

    abstract::The complete genome sequences of the human coronavirus OC43 (HCoV-OC43) laboratory strain from the American Type Culture Collection (ATCC), and a HCoV-OC43 clinical isolate, designated Paris, were obtained. Both genomes are 30,713 nucleotides long, excluding the poly(A) tail, and only differ by 6 nucleotides. These si...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: St-Jean JR,Jacomy H,Desforges M,Vabret A,Freymuth F,Talbot PJ

    更新日期:2004-08-01 00:00:00

  • Genome organization and reverse genetic analysis of a type I feline coronavirus.

    abstract::In this study we report the complete sequence and genome organization of the serotype I feline coronavirus (FCoV) strain Black. Furthermore, a reverse genetic system was established for this FCoV strain by cloning a full-length cDNA copy into vaccinia virus. This clone served as basis for the generation of recombinant...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Tekes G,Hofmann-Lehmann R,Stallkamp I,Thiel V,Thiel HJ

    更新日期:2008-02-01 00:00:00

  • Neuronal Subtype Determines Herpes Simplex Virus 1 Latency-Associated-Transcript Promoter Activity during Latency.

    abstract::Herpes simplex virus (HSV) latency in neurons remains poorly understood, and the heterogeneity of the sensory nervous system complicates mechanistic studies. In this study, we used primary culture of adult trigeminal ganglion (TG) mouse neurons in microfluidic devices and an in vivo model to examine the subtypes of se...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Cabrera JR,Charron AJ,Leib DA

    更新日期:2018-06-13 00:00:00

  • Identification of host-specificity determinants in betanodaviruses by using reassortants between striped jack nervous necrosis virus and sevenband grouper nervous necrosis virus.

    abstract::Betanodaviruses, the causal agents of viral nervous necrosis in marine fish, have bipartite positive-sense RNAs as genomes. The larger genomic segment, RNA1 (3.1 kb), encodes an RNA-dependent RNA polymerase, and the smaller genomic segment, RNA2 (1.4 kb), codes for the coat protein. Betanodaviruses have marked host sp...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Iwamoto T,Okinaka Y,Mise K,Mori K,Arimoto M,Okuno T,Nakai T

    更新日期:2004-02-01 00:00:00

  • Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice.

    abstract::SARS coronavirus (SARS-CoV) encodes several unique group-specific open reading frames (ORFs) relative to other known coronaviruses. To determine the significance of the SARS-CoV group-specific ORFs in virus replication in vitro and in mice, we systematically deleted five of the eight group-specific ORFs, ORF3a, OF3b, ...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Yount B,Roberts RS,Sims AC,Deming D,Frieman MB,Sparks J,Denison MR,Davis N,Baric RS

    更新日期:2005-12-01 00:00:00

  • High-frequency homologous recombination in vaccinia virus DNA.

    abstract::A recombinant vaccinia virus genome was constructed in which the viral thymidine kinase (tk) gene was placed between direct repeats of a 1.5-kilobase-pair DNA sequence of heterologous origin. When forced to replicate in tk- cells in the presence of methotrexate (i.e., under tk+-selective conditions), the recombinant m...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Ball LA

    更新日期:1987-06-01 00:00:00

  • Virulence determinants of avian H5N1 influenza A virus in mammalian and avian hosts: role of the C-terminal ESEV motif in the viral NS1 protein.

    abstract::We assessed the prediction that access of the viral NS1 protein to cellular PDZ domain protein networks enhances the virulence of highly pathogenic avian influenza A viruses. The NS1 proteins of most avian influenza viruses bear the C-terminal ligand sequence Glu-Ser-Glu-Val (ESEV) for PDZ domains present in multiple ...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Zielecki F,Semmler I,Kalthoff D,Voss D,Mauel S,Gruber AD,Beer M,Wolff T

    更新日期:2010-10-01 00:00:00

  • Role of naturally occurring basic amino acid substitutions in the human immunodeficiency virus type 1 subtype E envelope V3 loop on viral coreceptor usage and cell tropism.

    abstract::To assess the role of naturally occurring basic amino acid substitutions in the V3 loop of human immunodeficiency virus type 1 (HIV-1) subtype E on viral coreceptor usage and cell tropism, we have constructed a panel of chimeric viruses with mutant V3 loops of HIV-1 subtype E in the genetic background of HIV-1LAI. The...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Kato K,Sato H,Takebe Y

    更新日期:1999-07-01 00:00:00

  • Identification of amino acid substitutions supporting antigenic change of influenza A(H1N1)pdm09 viruses.

    abstract:UNLABELLED:The majority of currently circulating influenza A(H1N1) viruses are antigenically similar to the virus that caused the 2009 influenza pandemic. However, antigenic variants are expected to emerge as population immunity increases. Amino acid substitutions in the hemagglutinin protein can result in escape from ...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Koel BF,Mögling R,Chutinimitkul S,Fraaij PL,Burke DF,van der Vliet S,de Wit E,Bestebroer TM,Rimmelzwaan GF,Osterhaus AD,Smith DJ,Fouchier RA,de Graaf M

    更新日期:2015-04-01 00:00:00

  • The ORF012 gene of Marek's disease virus type 1 produces a spliced transcript and encodes a novel nuclear phosphoprotein essential for virus growth.

    abstract:UNLABELLED:Marek's disease virus (MDV), an alphaherpesvirus, is the causative agent of a lethal disease in chickens characterized by generalized nerve inflammation and rapid lymphoma development. The extensive colinearity of the MDV genome with those of related herpesviruses has eased functional characterization of man...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Schippers T,Jarosinski K,Osterrieder N

    更新日期:2015-01-15 00:00:00

  • Complete genome sequence of a Chinese virulent porcine epidemic diarrhea virus strain.

    abstract::CH/S is a virulent porcine epidemic diarrhea virus (PEDV) strain and is used as the virulent strain to evaluate the protection rates of vaccines against PEDV infection in China. Here, we report the complete genome sequence of strain CH/S, which may aid in understanding the molecular characteristics of this strain. ...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Chen J,Wang C,Shi H,Qiu HJ,Liu S,Shi D,Zhang X,Feng L

    更新日期:2011-11-01 00:00:00

  • Pneumopathogenicity in mice of a Sendai virus mutant, TSrev-58, is accompanied by in vitro activation with trypsin.

    abstract::The pneumopathogenicity of a trypsin-sensitive revertant of Sendai virus, TSrev-58, which was derived from a trypsin-resistant mutant, TR-5, was examined in mice. In comparison with TR-5, the revertant had a single amino acid substitution at residue 116 (Ile----Arg) on F protein, which was the cleavage site, and had t...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Mochizuki Y,Tashiro M,Homma M

    更新日期:1988-08-01 00:00:00

  • Poorly expressed endogenous ecotropic provirus of DBA/2 mice encodes a mutant Pr65gag protein that is not myristylated.

    abstract::DBA/2 mice carry a single endogenous ecotropic murine leukemia provirus designated Emv-3. Although this provirus appears to be nondefective by genomic restriction enzyme mapping, weanling mice do not produce virus and only about one-third of adult mice ever express virus. 5-Iododeoxyuridine and 5-azacytidine, two pote...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Copeland NG,Jenkins NA,Nexø B,Schultz AM,Rein A,Mikkelsen T,Jørgensen P

    更新日期:1988-02-01 00:00:00

  • Tropism of sheep lentiviruses for monocytes: susceptibility to infection and virus gene expression increase during maturation of monocytes to macrophages.

    abstract::Visna lentiviruses have a natural tropism for cells of the macrophage lineage of sheep and goats, but virus replication in these cells in vivo is restricted so that only small quantities of virus are produced. One restricting factor suggested in previous studies is that virus replication is dependent on the maturity o...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Gendelman HE,Narayan O,Kennedy-Stoskopf S,Kennedy PG,Ghotbi Z,Clements JE,Stanley J,Pezeshkpour G

    更新日期:1986-04-01 00:00:00

  • Complete genome sequence of a novel H9N2 subtype influenza virus FJG9 strain in China reveals a natural reassortant event.

    abstract::A/chicken/FJ/G9/09 (FJ/G9) is an H9N2 subtype avian influenza virus (H9N2 AIV) strain causing high morbidity that was isolated from broilers in Fujian Province of China in 2009. FJ/G9 has been used as the vaccine strain against H9N2 AIV infection in Fujian Province of China. Here, we report the complete genome sequenc...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Xie Q,Yan Z,Ji J,Zhang H,Liu J,Sun Y,Li G,Chen F,Xue C,Ma J,Bee Y

    更新日期:2012-09-01 00:00:00

  • Rotavirus infection increases intestinal motility but not permeability at the onset of diarrhea.

    abstract:UNLABELLED:The disease mechanisms associated with onset and secondary effects of rotavirus (RV) diarrhea remain to be determined and may not be identical. In this study, we investigated whether onset of RV diarrhea is associated with increased intestinal permeability and/or motility. To study the transit time, fluoresc...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Istrate C,Hagbom M,Vikström E,Magnusson KE,Svensson L

    更新日期:2014-03-01 00:00:00

  • The human papillomavirus type 8 E2 protein suppresses beta4-integrin expression in primary human keratinocytes.

    abstract::Human papillomaviruses (HPVs) infect keratinocytes of skin and mucosa. Homeostasis of these constantly renewing, stratified epithelia is maintained by balanced keratinocyte proliferation and terminal differentiation. Instructions from the extracellular matrix engaging integrins strongly regulate these keratinocyte fun...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Oldak M,Smola H,Aumailley M,Rivero F,Pfister H,Smola-Hess S

    更新日期:2004-10-01 00:00:00

  • Effect of calcium-modulating cyclophilin ligand on human immunodeficiency virus type 1 particle release and cell surface expression of tetherin.

    abstract::The human immunodeficiency virus type 1 (HIV-1) accessory protein Vpu enhances virus particle release by counteracting a host factor that retains virions at the surfaces of infected cells. It was recently demonstrated that cellular protein BST-2/CD317/Tetherin restricts HIV-1 release in a Vpu-dependent manner. Calcium...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Bego MG,Dubé M,Mercier J,Cohen EA

    更新日期:2009-12-01 00:00:00

  • Entry of vaccinia virus and cell-cell fusion require a highly conserved cysteine-rich membrane protein encoded by the A16L gene.

    abstract::The vaccinia virus A16L open reading frame encodes a 378-amino-acid protein with a predicted C-terminal transmembrane domain and 20 invariant cysteine residues that is conserved in all sequenced members of the poxvirus family. The A16 protein was expressed late in infection and incorporated into intracellular virus pa...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Ojeda S,Senkevich TG,Moss B

    更新日期:2006-01-01 00:00:00

  • MyD88-dependent immune activation mediated by human immunodeficiency virus type 1-encoded Toll-like receptor ligands.

    abstract::Immune activation is a major characteristic of human immunodeficiency virus type 1 (HIV-1) infection and a strong prognostic factor for HIV-1 disease progression. The underlying mechanisms leading to immune activation in viremic HIV-1 infection, however, are not fully understood. Here we show that, following the initi...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Meier A,Alter G,Frahm N,Sidhu H,Li B,Bagchi A,Teigen N,Streeck H,Stellbrink HJ,Hellman J,van Lunzen J,Altfeld M

    更新日期:2007-08-01 00:00:00

  • Morphf mutants of Rous sarcoma virus: nucleotide sequencing analysis suggests that a class of morphf mutants was generated through splicing of a cryptic intron.

    abstract::The nature of the lesions involved in producing the fusiform phenotype of three mutants (WO101, WO201, and tsST529) of the Schmidt-Ruppin A strain of Rous sarcoma virus (RSV) was determined by molecular cloning and DNA sequencing. WO101 and WO201 contained an in-frame deletion of the v-src region coding for amino acid...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Anderson SK,Fujita DJ

    更新日期:1987-06-01 00:00:00

  • Structure of the ribonucleoprotein of influenza virus.

    abstract::The ribonucleoprotein (RNP) internal components of influenza virus were separated into distinct size classes by sedimentation in glycerol gradients and examined by electron microscopy by using positive staining with uranyl acetate. The large RNP have a peak in length distribution at 90 to 110 nm, the medium, at 60 to ...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Compans RW,Content J,Duesberg PH

    更新日期:1972-10-01 00:00:00

  • Ribonucleic acid bacteriophage release: requirement for host-controlled protein synthesis.

    abstract::The release of the ribonucleic acid (RNA)-containing phage MS2 from Escherichia coli is accompanied by cellular lysis at 37 C, whereas at 30 C phage are released from intact cells. Chloramphenicol or rifampin prevents the release of progeny phage particles at both temperatures. Neither drug causes an immediate cessati...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Engelberg H,Soudry E

    更新日期:1971-09-01 00:00:00

  • Magnitude and frequency of cytotoxic T-lymphocyte responses: identification of immunodominant regions of human immunodeficiency virus type 1 subtype C.

    abstract::A systematic analysis of immune responses on a population level is critical for a human immunodeficiency virus type 1 (HIV-1) vaccine design. Our studies in Botswana on (i) molecular analysis of the HIV-1 subtype C (HIV-1C) epidemic, (ii) frequencies of major histocompatibility complex class I HLA types, and (iii) cyt...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Novitsky V,Cao H,Rybak N,Gilbert P,McLane MF,Gaolekwe S,Peter T,Thior I,Ndung'u T,Marlink R,Lee TH,Essex M

    更新日期:2002-10-01 00:00:00

  • Equine herpesvirus 1 gene 12 can substitute for vmw65 in the growth of herpes simplex virus (HSV) type 1, allowing the generation of optimized cell lines for the propagation of HSV vectors with multiple immediate-early gene defects.

    abstract::Herpes simplex virus (HSV) has often been suggested for development as a vector, particularly for the nervous system. Considerable evidence has shown that for use of HSV as a vector, immediate-early (IE) gene expression must be minimized or abolished, otherwise such vectors are likely to be highly cytotoxic. Mutations...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Thomas SK,Lilley CE,Latchman DS,Coffin RS

    更新日期:1999-09-01 00:00:00