Primary sarcoma of the adult vagina: a clinicopathologic study.

Abstract:

:Combination chemotherapy has dramatically improved the results of treatment for embryonal rhabdomyosarcoma of the vagina in children, but little attention has been directed toward vaginal sarcomas in adults. This report of 17 cases of primary sarcoma of the adult vagina includes ten leiomyosarcomas, four mixed mesodermal tumors, one undifferentiated sarcoma, one stromal sarcoma, and one neurofibrosarcoma. The leiomyosarcomas, mixed mesodermal tumors, and the stromal sarcoma were morphologically similar to their uterine counterparts. Thirty-five percent of the patients had received pelvic irradiation for carcinoma of the cervix. Three of four patients treated by pelvic exenteration are alive and disease free after 84 to 161 months of observation. All 13 patients who received other forms of primary therapy died of recurrence. The pelvis was the first site of recurrence in all treatment failures and the only site of failure in 50%.

journal_name

Obstet Gynecol

authors

Peters WA 3rd,Kumar NB,Andersen WA,Morley GW

subject

Has Abstract

pub_date

1985-05-01 00:00:00

pages

699-704

issue

5

eissn

0029-7844

issn

1873-233X

journal_volume

65

pub_type

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