Induction of labor using high-dose or low-dose prostaglandin vaginal pessaries.

Abstract:

:Two hundred women were studied in a randomized controlled trial of induction of labor using high-dose (3 mg) or low-dose (0.5 mg) prostaglandin E2 vaginal pessaries. Induction using 3-mg pessaries was more successful, with a shorter overall induction-delivery interval and less requirement for analgesia, although uterine hyperstimulation occurred in two patients. In contrast, the low-dose regimen did not cause hypertonus and, though less successful in inducing labor, the total dose of prostaglandin E2 used was considerably less than in the 3-mg group. The cesarean section rate when the cervix was initially unfavorable was high in both groups (high dose 18.2%, low dose 16.7%). The response to prostaglandin E2 did not relate closely to the initial cervical state.

journal_name

Obstet Gynecol

authors

Hunter IW,Cato E,Ritchie JW

subject

Has Abstract

pub_date

1984-03-01 00:00:00

pages

418-20

issue

3

eissn

0029-7844

issn

1873-233X

journal_volume

63

pub_type

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