Effect of gonadotropin-releasing hormone agonist on a uterine arteriovenous malformation.

Abstract:

BACKGROUND:The effect of gonadotropin-releasing hormone agonist (GnRHa) on uterine arteriovenous malformations (AVM) is not well known. CASE:A 37-year-old woman with a previous cesarean was diagnosed as having a uterine AVM after a spontaneous abortion with massive vaginal bleeding. The AVM decreased in size from 5.1 x 3.8 cm to 1.4 x 1.0 cm after 6 months of therapy with a GnRHa. Uterine artery embolization conducted after the GnRH therapy resulted in complete disappearance of the AVM. The patient's menstrual cycles and ovulation resumed 3 months after uterine artery embolization. CONCLUSION:Gonadotropin-releasing hormone agonist therapy reduced the size of the uterine AVM. Thus, GnRHa therapy may be useful for uterine AVM in situations where uterine artery embolization must be postponed.

journal_name

Obstet Gynecol

authors

Morikawa M,Yamada T,Yamada H,Minakami H

doi

10.1097/01.AOG.0000191584.28717.2c

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

751-3

issue

3 Pt 2

eissn

0029-7844

issn

1873-233X

pii

108/3/751

journal_volume

108

pub_type

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