A prospective comparison of hourly and quarter-hourly oxytocin dose increase intervals for the induction of labor at term.

Abstract:

:Fifty-two women undergoing labor induction and vaginal delivery at term were randomized between two oxytocin infusion protocols, involving hourly versus quarter-hourly increases in dose. Potential differences were sought of duration of labor, amount of uterine activity generated, and amount of oxytocin required. Starting at 0.5 mU/minute, oxytocin infusion was increased regularly in small increments every hour or every 15 minutes, according to group assignment. No differences were observed in potentially confounding clinical and demographic factors between the groups, including time to ruptured membranes. There were no clinically or statistically significant differences found for the duration of any phase or stage of labor, quantitative assessment of uterine activity, incidence of hyperstimulation, or neonatal outcome. The average dose of oxytocin used was lower in the hourly than in the quarter-hourly, protocol (4.4 versus 6.7 mU/minute; P less than .005). Significantly fewer patients on the hourly protocol required a maximum infusion rate exceeding 8 mU/minute (P less than .05). More patients on the hourly protocol either had oxytocin discontinued completely or were maintained at 4 mU/minute or less during the active phase of labor (P less than .05 and P less than .001, respectively). We conclude that a slower rate of increase in oxytocin administration via continuous infusion results in no prolongation of any phase of induced labor, while permitting lower infusion rates of the drug.

journal_name

Obstet Gynecol

authors

Blakemore KJ,Qin NG,Petrie RH,Paine LL

subject

Has Abstract

pub_date

1990-05-01 00:00:00

pages

757-61

issue

5

eissn

0029-7844

issn

1873-233X

journal_volume

75

pub_type

临床试验,杂志文章,随机对照试验
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    abstract:OBJECTIVE:To determine the opinions of obstetrics and gynecology residency program directors regarding the Residency Review Committee mandate, requires 6 months of primary care training in obstetrics and gynecology. METHODS:A ten-question survey was mailed to the 272 accredited obstetrics and gynecology programs in th...

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    pub_type: 杂志文章

    doi:10.1016/s0029-7844(97)00600-5

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    更新日期:1998-01-01 00:00:00

  • Early oral intake and gastrointestinal function after cesarean delivery: a systematic review and meta-analysis.

    abstract:OBJECTIVE:To evaluate whether early oral intake after cesarean delivery has an effect on gastrointestinal outcomes during postpartum recovery. DATA SOURCES:Electronic searches of published studies between 1980 and 2011 were conducted using PubMed, Medline, CINAHL, ClinicalTrials.gov, and Airiti databases. METHODS OF ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,meta分析,评审

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    authors: Hsu YY,Hung HY,Chang SC,Chang YJ

    更新日期:2013-06-01 00:00:00

  • Evaluation of amniotic fluid alpha-fetoprotein using an enzyme-linked immunosorbent assay.

    abstract::A simple, inexpensive enzyme-linked immunosorbent assay using commercially available supplies is described. An examination of amniotic fluid alpha-fetoprotein (AFP) values for 15 to 20 weeks' gestation is presented. The interassay coefficient of variation was 12% (N = 40) at a level of 4.75 micrograms/mL. Repeat freez...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Bogart MH,Winkelbauer D,Jones OW

    更新日期:1985-09-01 00:00:00

  • Weight gain in pregnancy, triceps skinfold thickness, and blood pressure in offspring.

    abstract:OBJECTIVE:To determine whether women who are poorly nourished in early pregnancy, as determined by triceps skinfold thickness, or who have poor pregnancy weight gain have offspring with higher blood pressure (BP). METHODS:We evaluated 296 11-year-old children born to women who had taken part in a study of nutrition in...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(97)00581-4

    authors: Clark PM,Atton C,Law CM,Shiell A,Godfrey K,Barker DJ

    更新日期:1998-01-01 00:00:00

  • Distressing Sexual Function at Midlife: Unmet Needs, Practical Diagnoses, and Available Treatments.

    abstract::Female sexual dysfunction (FSD) is characterized as chronic sexual symptoms that manifest with personal distress in the domains of desire, arousal, orgasm, and pain. Extensive epidemiologic evidence estimates that almost 50% of perimenopausal and postmenopausal women experience FSD. Screening for FSD is not readily co...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000002268

    authors: Simon JA,Lukas VA

    更新日期:2017-10-01 00:00:00

  • Maternal-fetal surgery: where are we and how did we get here?

    abstract::Using the criteria proposed in 1982 to justify consideration of in utero surgical treatment of fetal disorders, the development of maternal-fetal treatment is described, and an assessment of current status is provided. Significant issues remain, and many questions are unanswered. By using three different disorders, co...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/AOG.0b013e318197c28f

    authors: Chescheir NC

    更新日期:2009-03-01 00:00:00

  • Committee Opinion No. 644: The Apgar Score.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001108

    authors:

    更新日期:2015-10-01 00:00:00

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/01.AOG.0000161958.70059.db

    authors: Potts RO,Lobo RA

    更新日期:2005-05-01 00:00:00

  • Successful spontaneous vaginal delivery during mechanical ventilatory support for the adult respiratory distress syndrome.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Sosin D,Krasnow J,Moawad A,Hall JB

    更新日期:1986-09-01 00:00:00

  • Combining vaginal ultrasonography and office endometrial sampling in the diagnosis of endometrial disease in postmenopausal women.

    abstract:OBJECTIVE:To investigate the value of the combined use of vaginal ultrasonography and endometrial sampling in the office for the diagnosis of endometrial disease in postmenopausal women. METHODS:One hundred forty consecutive postmenopausal women presenting with uterine bleeding or endometrial cells on cervical cytolog...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:10.1016/0029-7844(94)00421-9

    authors: Van den Bosch T,Vandendael A,Van Schoubroeck D,Wranz PA,Lombard CJ

    更新日期:1995-03-01 00:00:00

  • Nonfluorescent erythrasma of the vulva.

    abstract:BACKGROUND:Erythrasma is an uncommon vulvar infection, best diagnosed by its fluorescence under the Wood lamp. This report shows that despite a negative Wood lamp examination, the diagnosis can be made histologically. CASE:A 42-year-old woman was referred to our clinic with a persistent candidal infection. Evaluation ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Mattox TF,Rutgers J,Yoshimori RN,Bhatia NN

    更新日期:1993-05-01 00:00:00

  • Tubal pregnancy with normal hysterosalpingogram and negative serum pregnancy test.

    abstract::A patient undergoing evaluation for primary infertility with regular menses had a normal hysterosalpingogram in the follicular phase and underwent diagnostic laparoscopy the next day, with the finding of a tubal pregnancy. The patient had a negative serum pregnancy test. Although a normal hysterosalpingogram and negat...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Uribe MA,Dunn RC,Buttram VC Jr

    更新日期:1990-03-01 00:00:00

  • von Willebrand's disease diagnosed after menorrhagia worsened from levonorgestrel intrauterine system.

    abstract:BACKGROUND:Adult females with menorrhagia may have unrecognized mild von Willebrand's disease. Most females with known von Willebrand's disease report menorrhagia. CASE:A 38-year-old healthy female desired contraception. She described heavy menses lasting 8 days since menarche. History included uncomplicated vaginal d...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000157758.94890.59

    authors: Lukes AS,Perry S,Ortel TL

    更新日期:2005-05-01 00:00:00

  • Blood transfusion for radical hysterectomy before and after the discovery of transfusion-related human immunodeficiency virus infection.

    abstract:OBJECTIVE:To compare the patterns of perioperative blood transfusion in patients undergoing radical hysterectomy in time periods before and after the discovery of transfusion-related human immunodeficiency virus (HIV) infection. METHODS:We reviewed the medical records of all patients who underwent radical hysterectomy...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Benjamin I,Barakat RR,Curtin JP,Jones WB,Lewis JL Jr,Hoskins WJ

    更新日期:1994-12-01 00:00:00

  • Hormone therapy prescribing patterns in the United States.

    abstract:OBJECTIVE:We sought to examine prescribing patterns (prevalence and rates of initiation and discontinuation) for estrogen plus progestin (hormone therapy [HT] and estrogen alone [ET]) in the United States in the 2 years before the published results of Women's Health Initiative's (WHI) HT trial's early termination and f...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000143826.38439.af

    authors: Buist DS,Newton KM,Miglioretti DL,Beverly K,Connelly MT,Andrade S,Hartsfield CL,Wei F,Chan KA,Kessler L

    更新日期:2004-11-01 00:00:00

  • Macrophage colony-stimulating factor as a tumor marker for epithelial ovarian cancer.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Suzuki M,Ohwada M,Aida I,Tamada T,Hanamura T,Nagatomo M

    更新日期:1993-12-01 00:00:00

  • The process of resident selection: a view from the residency director's desk.

    abstract::In 1992, the Executive Council of the Association of American Medical Colleges recommended that a computerized application system be investigated. Under this system, the application package would include: 1) a standardized application form, 2) a personal statement, 3) a dean's letter, 4) transcripts, 5) a chairman's l...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(94)00388-T

    authors: Taylor CA,Weinstein L,Mayhew HE

    更新日期:1995-02-01 00:00:00

  • Vaginal correction of pelvic organ relaxation using local anesthesia.

    abstract:OBJECTIVE:To describe the technique and complications of vaginal repair of advanced pelvic organ prolapse using intravenous sedation, pudendal nerve block, and local anesthesia. METHODS:A retrospective review of the gynecologic surgical records of 20 patients was performed. Patient demographics, surgical procedure, su...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(95)00331-k

    authors: Miklos JR,Sze EH,Karram MM

    更新日期:1995-12-01 00:00:00

  • Antecedent history as a predictor of surgical cure of urgency symptoms in mixed incontinence.

    abstract:OBJECTIVE:To determine the cure rate of urge incontinence after Burch colposuspension in patients with mixed incontinence diagnosed urodynamically, to determine if cure rates were different when the onset of urge symptoms antedated or postdated the symptoms of stress incontinence, and to propose appropriate preoperativ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(97)00550-4

    authors: Scotti RJ,Angell G,Flora R,Greston WM

    更新日期:1998-01-01 00:00:00

  • Combination Antiretroviral Therapy and Hypertensive Disorders of Pregnancy.

    abstract:OBJECTIVE:To compare the incidence of hypertensive disorders of pregnancy among women living with human immunodeficiency virus (HIV) on combination antiretroviral therapy (ART) to women without HIV, and to evaluate the association of hypertensive disorders of pregnancy with ART regimens or timing of ART initiation. ME...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000003584

    authors: Saums MK,King CC,Adams JC,Sheth AN,Badell ML,Young M,Yee LM,Chadwick EG,Jamieson DJ,Haddad LB

    更新日期:2019-12-01 00:00:00

  • Racial Disparities in Mental Health Outcomes Among Women With Early Pregnancy Loss.

    abstract:OBJECTIVE:To explore the relationship between race and depression symptoms among participants in an early pregnancy loss clinical trial. METHODS:We performed a planned secondary analysis of a randomized trial by comparing treatments for medical management of early pregnancy loss. We hypothesized that Black participant...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000004212

    authors: Shorter JM,Koelper N,Sonalkar S,Oquendo MA,Sammel MD,Schreiber CA

    更新日期:2021-01-01 00:00:00

  • The epidemiology of pregnancy complications and outcome in a Norwegian twin population.

    abstract:OBJECTIVE:To measure the contribution of genetic factors to selected pregnancy complications, including miscarriage, twinning, hypertension-toxemia, and nausea-vomiting. METHODS:Information on 22,241 pregnancies of 8675 female twins or spouses of male twins was obtained by questionnaire from members of the population-...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Corey LA,Berg K,Solaas MH,Nance WE

    更新日期:1992-12-01 00:00:00

  • Antepartum external cephalic version under tocolysis.

    abstract::Reported are 172 patients considered for external cephalic version at gestational age greater than 37 weeks. Their outcome was compared with 40 similar patients in whom external version was not attempted. One hundred fifty-eight patients had attempted version, and success was achieved in 122 (77%). Intrapartum vertex ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Dyson DC,Ferguson JE 2nd,Hensleigh P

    更新日期:1986-01-01 00:00:00

  • Surveillance and management of patients at high genetic risk for ovarian carcinoma.

    abstract::The present study is concerned with surveillance/management programs for hereditary ovarian cancer syndromes. These syndromes lack distinguishing premonitory physical signs or biomarkers; therefore, in these genotypic settings, ovarian cancer risk must be assessed by analysis of the patient's pedigree. The authors des...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Lynch HT,Albano WA,Lynch JF,Lynch PM,Campbell A

    更新日期:1982-05-01 00:00:00

  • Time interval between endometrial biopsy and surgical staging for type I endometrial cancer: association between tumor characteristics and survival outcome.

    abstract:OBJECTIVE:To examine whether wait time between endometrial biopsy and surgical staging correlates with tumor characteristics and affects survival outcomes in patients with type I endometrial cancer. METHODS:A retrospective study was conducted to examine patients with grade 1 and 2 endometrioid adenocarcinoma diagnosed...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000636

    authors: Matsuo K,Opper NR,Ciccone MA,Garcia J,Tierney KE,Baba T,Muderspach LI,Roman LD

    更新日期:2015-02-01 00:00:00

  • Maternal serum levels of placental protein 5 in complications of late pregnancy.

    abstract::Maternal serum levels of placental protein 5 (PP5) were measured during the third trimester in women with normal and abnormal pregnancies. PP5 levels were significantly elevated in patients with preeclampsia, diabetes, intrauterine growth retardation associated with preeclampsia, and twin pregnancy. ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Salem HT,Westergaard JG,Hindersson P,Lee JN,Grudzinskas JG,Chard T

    更新日期:1982-04-01 00:00:00

  • Pain perception in women with dysmenorrhea.

    abstract:OBJECTIVE:To determine if systemic processing of pain differs in women with and without dysmenorrhea. METHODS:Twenty-two dysmenorrheic women and 31 nondysmenorrheic women were studied by pain threshold and supra-threshold magnitude estimation to heat stimuli, pain-evoked potentials by laser stimuli, and anxiety scores...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(01)01465-x

    authors: Granot M,Yarnitsky D,Itskovitz-Eldor J,Granovsky Y,Peer E,Zimmer EZ

    更新日期:2001-09-01 00:00:00

  • Massive blood transfusion during hospitalization for delivery in New York State, 1998-2007.

    abstract:OBJECTIVE:To define the frequency, risk factors, and outcomes of massive transfusion in obstetrics. METHODS:The State Inpatient Dataset for New York (1998-2007) was used to identify all delivery hospitalizations for hospitals that reported at least one delivery-related transfusion per year. Multivariable logistic regr...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000021

    authors: Mhyre JM,Shilkrut A,Kuklina EV,Callaghan WM,Creanga AA,Kaminsky S,Bateman BT

    更新日期:2013-12-01 00:00:00

  • Determinants of postoperative outcomes of female genital fistula repair surgery.

    abstract:OBJECTIVE:To determine predictors of fistula repair outcomes 3 months postsurgery. METHODS:We conducted a multicountry prospective cohort study between 2007 and 2010. Outcomes, measured 3 months postsurgery, included fistula closure and residual incontinence in women with a closed fistula. Potential predictors include...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1097/AOG.0b013e31826579e8

    authors: Barone MA,Frajzyngier V,Ruminjo J,Asiimwe F,Barry TH,Bello A,Danladi D,Ganda SO,Idris S,Inoussa M,Lynch M,Mussell F,Podder DC

    更新日期:2012-09-01 00:00:00

  • First- and second-trimester evaluation of risk for Down syndrome.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000263470.89007.e3

    authors: Ball RH,Caughey AB,Malone FD,Nyberg DA,Comstock CH,Saade GR,Berkowitz RL,Gross SJ,Dugoff L,Craigo SD,Timor-Tritsch IE,Carr SR,Wolfe HM,Emig D,D'Alton ME,First and Second Trimester Evaluation of Risk (FASTER) Research Consor

    更新日期:2007-07-01 00:00:00