The genetics of intersexuality: clinical and theoretic perspectives.

Abstract:

:Recent studies using newly devised serologic techniques have dramatically advanced our understanding of gonadal organogenesis and aberrant sexual differentiation. Thus XY gonadal dysgenesis, XX male syndrome, and XX true hermaphroditism, for example, may be seen as typifying specific errors of regulation, synthesis, or function of a phylogenetically conserved plasma membrane component heretofore recognized solely as the male-specific transplantation antigen of mice. This report seeks to convey the excitement of these recent studies, and to provide the clinician with new and useful insights into the fundamental mechanism of primary sex determination.

journal_name

Obstet Gynecol

authors

Wachtel SS

subject

Has Abstract

pub_date

1979-12-01 00:00:00

pages

671-85

issue

6

eissn

0029-7844

issn

1873-233X

journal_volume

54

pub_type

杂志文章,评审
  • Alcohol abuse during pregnancy: changes in frequency in a large urban hospital.

    abstract::The reported frequency of alcohol abuse during pregnancy was studied in a large urban public hospital in Dallas, Texas. During 1977-1980, 5602 pregnant women were surveyed and 0.7% (95% confidence interval 0.6-0.8%) reported abusing alcohol during pregnancy. In 1987, 1.4% (95% confidence interval 1.3-1.5%) of 1032 pre...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Little BB,Snell LM,Gilstrap LC 3rd,Gant NF,Rosenfeld CR

    更新日期:1989-10-01 00:00:00

  • ACOG Committee Opinion No. 409: Direct-to-consumer marketing of genetic testing.

    abstract::Marketing of genetic testing, although similar to direct-to-consumer advertising of prescription drugs, raises additional concerns and considerations. These include issues of limited knowledge among patients and health care providers of available genetic tests, difficulty in interpretation of genetic testing results, ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,实务指引

    doi:10.1097/AOG.0b013e31817d250e

    authors: Committee on Genetics, American College of Obstetricians and Gynecologists.,Committee on Ethics, American College of Obstetricians and Gynecologists.

    更新日期:2008-06-01 00:00:00

  • Body mass index and outcome of incontinence surgery.

    abstract:OBJECTIVE:To analyze the influence of body mass on the outcome of surgery for urinary incontinence. METHODS:Among 291 women operated on for stress incontinence, 187 (64%) were available for follow-up at 5 years. Eighty women had anterior colporrhaphy, 49 anterior colporrhaphy with needle suspension of the bladder neck...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(98)00513-4

    authors: Zivkovic F,Tamussino K,Pieber D,Haas J

    更新日期:1999-05-01 00:00:00

  • Scheduled hysterectomy for second-trimester abortion in a patient with placenta accreta.

    abstract:BACKGROUND:As cesarean deliveries increase, so does placenta accreta. There is little evidence regarding management of patients with known or suspected abnormal placentation seeking abortion. CASE:A medically complicated patient with evidence of placenta increta on magnetic resonance imaging presented for pregnancy te...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e318194258c

    authors: Tocce K,Thomas VW,Teal S

    更新日期:2009-02-01 00:00:00

  • Risk of large-for-gestational-age newborns in women with gestational diabetes by race and ethnicity and body mass index categories.

    abstract:OBJECTIVE:To compare the prevalence of large-for-gestational-age (LGA) newborns across categories of body mass index (BMI) in five racial and ethnic groups. METHODS:This cohort study examined 7,468 women with gestational diabetes mellitus (GDM) who delivered a live newborn between 1995 and 2006 at Kaiser Permanente No...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e318291b15c

    authors: Sridhar SB,Ferrara A,Ehrlich SF,Brown SD,Hedderson MM

    更新日期:2013-06-01 00:00:00

  • Discrepancy in the interpretation of cervical histology by gynecologic pathologists.

    abstract:OBJECTIVE:To determine if subspecialty review of cervical histology improves diagnostic consensus of cervical intraepithelial neoplasia (CIN). METHODS:After routine histologic assessment within the hospital pathology department, 119 colposcopic cervical biopsies were interpreted by two subspecialty-trained gynecologic...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(02)02058-6

    authors: Parker MF,Zahn CM,Vogel KM,Olsen CH,Miyazawa K,O'Connor DM

    更新日期:2002-08-01 00:00:00

  • Ectopic pancreas in the fallopian tube. Report of a first case.

    abstract::A case of ectopic pancreas in the fallopian tube is reported. This small, polypoid, benign tumor was in a fallopian tube contralateral to a ruptured tubal pregnancy. The patient had a tubal ligation performed six years previously. To the best of our knowledge this is the first reported case of isolated ectopic pancrea...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Mason TE,Quagliarello JR

    更新日期:1976-07-01 00:00:00

  • Tumor angiogenesis as a predictor of recurrence in stage Ib squamous cell carcinoma of the cervix.

    abstract:OBJECTIVE:To explore the possibility of using histologic microvessel count of sections from the tumor to predict recurrence of stage Ib squamous cell carcinoma of the cervix. METHODS:Tumor sections from 22 patients (11 patients free of disease after 3 years and 11 patients with recurrence) were stained histoimmunochem...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(96)00039-7

    authors: Dinh TV,Hannigan EV,Smith ER,Hove MJ,Chopra V,To T

    更新日期:1996-05-01 00:00:00

  • Menstrual cyclicity after metformin therapy in polycystic ovary syndrome.

    abstract:OBJECTIVE:To assess the effect of insulin-lowering treatment on menstrual cyclicity in polycystic ovary syndrome (PCOS). METHODS:Forty oligoamenorrheic women with PCOS were recruited in a prospective clinical study to receive metformin for a minimum period of 6 months. Twenty-two women completed the study. Serum LH, F...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0029-7844(97)00296-2

    authors: Velázquez E,Acosta A,Mendoza SG

    更新日期:1997-09-01 00:00:00

  • Maternal hydration increases amniotic fluid index in women with normal amniotic fluid.

    abstract:OBJECTIVE:To test the hypothesis that maternal oral hydration would increase the amniotic fluid (AF) index in pregnancies with normal AF. METHODS:Forty women with a normal AF index (7.0-24.0 cm) were randomized to either the control or hydration group. Women in the hydration group drank 2 L of water and returned for t...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Kilpatrick SJ,Safford KL

    更新日期:1993-01-01 00:00:00

  • Plasma catecholamines and angiotensin-converting enzyme activity in hypertensive subjects with positive rollover tests.

    abstract::The rollover test is useful in predicting and identifying subjects developing hypertensive disorders of pregnancy. The mechanisms responsible for positive tests are unclear, but a greater release of pressor substances occurring in subjects with positive tests has been proposed. The authors measured and compared heart ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Lee MI,Todd HM

    更新日期:1984-04-01 00:00:00

  • Maternal and neonatal death due to pneumococcal infection.

    abstract::A 27-year-old woman died from pneumococcal meningitis associated with pneumococcal endometritis two days after being delivered of a .1.75-kg infant. The infant also had pneumococcal septicemia and died six days after birth. The pneumococcus isolated from the mother and the baby was type 8. The membranes had ruptured 2...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Hutchison CP,Kenney A,Eykyn S

    更新日期:1984-01-01 00:00:00

  • Rapid B-scan (real-time) ultrasonography in the identification and evaluation of twin pregnancies.

    abstract::Real-time ultrasonography utilizing a hand-held linear array transducer provides a highly accurate method of identifying and evaluating the twin gestation. The rapidity of real-time scanning eliminates interpretational problems caused by fetal movements. Additionally, the versatility of transducer positioning facilita...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Levine SC,Filly RA

    更新日期:1978-02-01 00:00:00

  • Condylomatous carcinoma of the vulva with special reference to human papillomavirus DNA.

    abstract::Nine cases of condylomatous carcinoma (squamous cell carcinoma arising in condyloma acuminatum) of the vulva were studied for their clinical history, histopathology, and presence of human papillomavirus (HPV) DNA. Condylomatous carcinoma occurred primarily in an elderly population with a mean age of 70 years. There wa...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Downey GO,Okagaki T,Ostrow RS,Clark BA,Twiggs LB,Faras AJ

    更新日期:1988-07-01 00:00:00

  • Comparative Effectiveness of Uterine Leiomyoma Procedures Using a Large Insurance Claims Database.

    abstract:OBJECTIVE:To compare risk of reintervention, long-term clinical outcomes, and health care utilization among women who have bulk symptoms from leiomyoma and who underwent the following procedures: hysterectomy, myomectomy, uterine artery embolization, and magnetic resonance-guided, focused ultrasound surgery. METHODS:T...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000002331

    authors: Borah BJ,Yao X,Laughlin-Tommaso SK,Heien HC,Stewart EA

    更新日期:2017-11-01 00:00:00

  • Trends and Predictors of Cerclage Use in the United States From 2005 to 2012.

    abstract:OBJECTIVE:To characterize the use of cervical cerclage on a population basis. METHODS:This population-based study of U.S. natality records from 2005 to 2012 evaluated use of cerclage in singleton and multiple gestation live births. Obstetric, medical, and demographic characteristics were evaluated. A multivariable log...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000930

    authors: Friedman AM,Ananth CV,Siddiq Z,D'Alton ME,Wright JD

    更新日期:2015-08-01 00:00:00

  • Influence of pregnancy weight gain on the size of infants born to underweight women.

    abstract::The influence of weight gain during pregnancy on duration of gestation and infant size at birth was examined among women beginning pregnancy underweight and at normal weight. Results of the review of 654 prenatal and delivery records revealed that 1) Prepregnancy weight status was not associated with the amount of wei...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Brown JE,Jacobson HN,Askue LH,Peick MG

    更新日期:1981-01-01 00:00:00

  • Botulinum neurotoxin type A injections for vaginismus secondary to vulvar vestibulitis syndrome.

    abstract:OBJECTIVE:To investigate whether botulinum neurotoxin type A improves vaginismus and study its efficacy with repeated treatments. METHODS:Outpatients were referred because standard cognitive-behavioral and medical treatment for vaginismus and vulvar vestibular syndrome failed. From this group, we prospectively recruit...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e3181bb0dbb

    authors: Bertolasi L,Frasson E,Cappelletti JY,Vicentini S,Bordignon M,Graziottin A

    更新日期:2009-11-01 00:00:00

  • Effect of human immunodeficiency virus treatment on maternal mortality at a tertiary center in South Africa: a 5-year audit.

    abstract:OBJECTIVE:To review facility-based maternal deaths at a tertiary-level center in Johannesburg, South Africa, during a 5-year period (2003 to 2007) and to investigate the proportion of deaths attributable to human immunodeficiency virus (HIV), the etiology of deaths, and the effects of antiretroviral treatment introduce...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e3181af33e6

    authors: Black V,Brooke S,Chersich MF

    更新日期:2009-08-01 00:00:00

  • Tubal anastomosis by robotic compared with outpatient minilaparotomy.

    abstract:OBJECTIVE:To compare tubal anastomosis by robotic system compared with outpatient minilaparotomy. METHODS:In this retrospective case-control study, women were identified by current procedural terminology code for tubal anastomosis. We included all cases of tubal anastomosis for reversal of a prior tubal ligation by ei...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000264591.43544.0f

    authors: Rodgers AK,Goldberg JM,Hammel JP,Falcone T

    更新日期:2007-06-01 00:00:00

  • Analysis of cryolesions in the uterine cervix: application techniques, extension, and failures.

    abstract::Although cryosurgery is regularly used for treatment of cervical intraepithelial neoplasia (CIN), there are few data concerning freeze technique and attendant extension of the cryolesion. This study evaluated how to create cryolesions extensive enough to eradicate the CIN lesion completely. The way the extension of th...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Boonstra H,Koudstaal J,Oosterhuis JW,Wymenga HA,Aalders JG,Janssens J

    更新日期:1990-02-01 00:00:00

  • Radiation risks in pregnancy.

    abstract::A major contraindication of radiodiagnostic procedures is pregnancy. Approximately 1% of all pregnant women are given abdominal x-rays during the first trimester of pregnancy. Evaluation of radiation exposure should involve consideration of the types of examinations performed and when performed, as well as radiation d...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:

    authors: Mossman KL,Hill LT

    更新日期:1982-08-01 00:00:00

  • Longitudinal study of the amniotic fluid index in post-dates pregnancy.

    abstract::Amniotic fluid (AF) was measured in 511 post-dates pregnancies (at least 41 weeks of gestational age) with the use of the AF index. Ultrasonographic evaluations were conducted on a semiweekly basis. Only patients with reliable gestational ages calculated from certain last menstrual period and confirmed by early sonogr...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Marks AD,Divon MY

    更新日期:1992-02-01 00:00:00

  • Normal endometrial cells in Papanicolaou smears: prevalence in women with and without endometrial disease.

    abstract:OBJECTIVE:To determine whether the prevalence of normal endometrial cells in Papanicolaou smears of women with and those without endometrial carcinoma or hyperplasia differs significantly. METHODS:Papanicolaou smears of women with biopsy-proved endometrial hyperplasia or carcinoma diagnosed between 1990 and 1998 were ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(00)01038-3

    authors: Gomez-Fernandez CR,Ganjei-Azar P,Behshid K,Averette HE,Nadji M

    更新日期:2000-12-01 00:00:00

  • Experimental hyperprolactinemia and hypoprolactinemia and human chorionic gonadotropin during early pregnancy.

    abstract::The effect of experimental hyperprolactinemia and hypoprolactinemia on human chorionic gonadotropin (hCG) concentration was studied in 34 healthy volunteers between weeks 6 and 11 of normal pregnancy. Hyperprolactinemia was induced in 12 women with 150 mg of sulpiride daily for 2 weeks; treatment led to a mean plasma ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Viinikka L,Kivinen S,Rönnberg L,Ylikorkala O

    更新日期:1981-04-01 00:00:00

  • Interpreting the literature in obstetrics and gynecology: II. Logistic regression and related issues.

    abstract::The goal of epidemiology is accurate measure of the relationship between an exposure and a disease of interest. The control of covariates of the exposure-disease relationship is required to obtain a valid measure. Two types of covariates, confounders and effect modifiers, must be considered. Investigators can design s...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:

    authors: Peterson HB,Kleinbaum DG

    更新日期:1991-10-01 00:00:00

  • Diagnosis and management of epithelial ovarian cancer.

    abstract::Epithelial ovarian cancer is the leading cause of death from gynecologic cancer in the United States. Although there has been a statistically significant improvement in 5-year survival, in 2005 more than 16,000 women were expected to die of this disease. To date, there is no reliable method to screen for ovarian cance...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/01.AOG.0000220516.34053.48

    authors: Bhoola S,Hoskins WJ

    更新日期:2006-06-01 00:00:00

  • Post-term birth: risk factors and outcomes in a 10-year cohort of Norwegian births.

    abstract:OBJECTIVE:To identify factors associated with post-term birth and factors associated with adverse outcomes in post-term births. METHODS:The sample was a 10-year cohort (1978-1987) of term (n = 379,445) and post-term (n = 65,796) births from the Medical Birth Registry of Norway. Gestational age was based on mothers' re...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(97)00049-5

    authors: Campbell MK,Ostbye T,Irgens LM

    更新日期:1997-04-01 00:00:00

  • Acardiac twin pregnancy with neonatal resolution of donor twin cardiomyopathy.

    abstract:BACKGROUND:Twin reverse arterial perfusion, as with acardiac fetuses, is a rare complication of multifetal pregnancy. Prognosis of the donor twin is guarded because of the high risk of cardiac failure, polyhydramnios, and preterm delivery. CASE:A 40-year-old woman, gravida 4, para 3, was diagnosed at 19 weeks' gestati...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(00)01042-5

    authors: Chandra S,Crane JM,Young DC,Shah S

    更新日期:2000-11-01 00:00:00

  • Head-to-cervix forces and their relationship to the outcome of labor.

    abstract::The force (as distinct from pressure) between the fetal head and the maternal cervix during labor was measured for the first time in an attempt to improve the intrapartum prediction of progress in labor. The 50th percentile of the variables active pressure and active force and the mean uterine activity integral were c...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Gough GW,Randall NJ,Genevier ES,Sutherland IA,Steer PJ

    更新日期:1990-04-01 00:00:00