Condylomatous carcinoma of the vulva with special reference to human papillomavirus DNA.

Abstract:

:Nine cases of condylomatous carcinoma (squamous cell carcinoma arising in condyloma acuminatum) of the vulva were studied for their clinical history, histopathology, and presence of human papillomavirus (HPV) DNA. Condylomatous carcinoma occurred primarily in an elderly population with a mean age of 70 years. There was an antecedent history of vulvar condyloma in 77%, with a median of nine months before the documentation of an invasive lesion. The disease had a good prognosis, with few recurrences and no metastasis or deaths from the disease. Human papillomavirus DNA was demonstrated to be present in 55% of these tumors by either filter or in situ hybridization techniques. Both HPV 6 and HPV 16 DNA were identified in an equal number of cases.

journal_name

Obstet Gynecol

authors

Downey GO,Okagaki T,Ostrow RS,Clark BA,Twiggs LB,Faras AJ

subject

Has Abstract

pub_date

1988-07-01 00:00:00

pages

68-73

issue

1

eissn

0029-7844

issn

1873-233X

journal_volume

72

pub_type

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