Abstract：
:Although cryosurgery is regularly used for treatment of cervical intraepithelial neoplasia (CIN), there are few data concerning freeze technique and attendant extension of the cryolesion. This study evaluated how to create cryolesions extensive enough to eradicate the CIN lesion completely. The way the extension of the cryolesion was influenced by type of probe, anatomical position in the cervix, shape of the external os, and freeze time was analyzed. Furthermore, we examined whether localization of the cryolesions corresponded with the CIN III location. Cryosurgery was applied to the cervix of 64 women the day before hysterectomy was performed for benign disease. Four types of probes were tested and freezing was done with a double freeze cycle. After extirpation of the uterus, slides were cut at the 3-, 6-, 9-, and 12-o'clock positions. With a computerized graphic tablet, the depth and linear extension of the cryolesion were measured morphometrically. After short freeze times, it appeared that an adequate lesion was present in only 67.4% of the slides. The large cone probe gave the best results; the small flat cervix probe the worst. At the 3- and 9-o'clock positions, a significantly higher percentage of inadequate lesions was found (60.8 and 65.3%, respectively). This proved to be due primarily to the extensive vascular supply at those positions. Longer freeze times gave an excellent result within all slides, even at the 3- and 9-o'clock positions. The topographic position of the cryolesion corresponded completely in all cases with that of the CIN III lesion.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Boonstra H,Koudstaal J,Oosterhuis JW,Wymenga HA,Aalders JG,Janssens Jsubject
Has Abstractpub_date
1990-02-01 00:00:00pages
232-9issue
2eissn
0029-7844issn
1873-233Xjournal_volume
75pub_type
杂志文章abstract：:Although pneumonia complicating pregnancy remains an unusual occurrence, it can have serious consequences for both the mother and fetus. Although Streptococcus pneumoniae remains the most common bacterial pathogen, recent epidemics have emphasized the importance of considering Legionella pneumophila as the etiologic a...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-198603001-00003
更新日期：1986-03-01 00:00:00
abstract：:Five hundred twelve patients who presented with initial atypical cervical cytology between February 1982 and February 1983 at Naval Hospital, San Diego were randomized with respect to antibiotic treatment and interval before repeat cytologic examination. Treatment before repeat cytology did not improve the rate of rev...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1986-08-01 00:00:00
abstract：OBJECTIVE:To estimate the efficacy, cycle control, tolerability, and safety of a monophasic combined oral contraceptive containing nomegestrol acetate and 17β-estradiol (E2) in comparison with drospirenone and ethinyl E2. METHODS:In a randomized, open-label, comparative multicenter trial, healthy women (n=2,281; age 1...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1097/AOG.0b013e318250c3a0
更新日期：2012-05-01 00:00:00
abstract：:A 21-year-old white woman presented with virilization, hirsutism, and acne of 1.5 years' duration. Endocrine testing demonstrated complete suppression of serum testosterone, from 5.3 to 0.6 ng/mL, and serum androstenedione, from 4.7 to 1.7 ng/mL, after oral administration of 50 micrograms of mestranol and 1 mg of nore...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1989-05-01 00:00:00
abstract：OBJECTIVE:To estimate prevalence and correlates of abortion provision among practicing obstetrician-gynecologists (ob-gyns) in the United States. METHODS:We conducted a national probability sample mail survey of 1,800 practicing ob-gyns. Key variables included whether respondents ever encountered patients seeking abor...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e31822ad973
更新日期：2011-09-01 00:00:00
abstract：:Sickle cell anemia is associated with an alarming attrition rate during pregnancy. The maternal morbidity rate, perinatal wastage rate, and the incidence of severe morbidity in both mother and child are elevated above acceptable limits. In most cases, these statistics have been compiled using conservative therapeutic ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1976-11-01 00:00:00
abstract：BACKGROUND:Combined deficiency of vitamin K-dependent coagulation factors (II, VII, IX, X) is an uncommon challenge for the expectant gravida. CASE:A 34-year-old primigravida had congenital combined deficiency of factors II, VII, IX, and X that were incompletely sensitive to vitamin K. She had an altered form of vitam...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(00)01214-x
更新日期：2001-05-01 00:00:00
abstract：OBJECTIVE:Adverse fetal heart rate (FHR) changes occur frequently during the first 30 minutes after epidural analgesia. The aim of this study was to estimate whether intravenous administration of ephedrine during induction of epidural analgesia can reduce the frequency of adverse FHR changes. METHODS:We prospectively ...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/01.AOG.0000146281.05275.73
更新日期：2004-12-01 00:00:00
abstract：BACKGROUND:We report a highly exceptional case in which a gonadotroph adenoma was diagnosed in a patient with normal follicle-stimulating hormone (FSH) levels. CASE:A 30-year-old woman with a gonadotroph adenoma presented with hyperstimulation syndrome and normal FSH levels. After treatment of her adenoma she had regu...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000247316.60573.4a
更新日期：2007-02-01 00:00:00
abstract：:Heavy menstrual bleeding is defined as excessive menstrual blood loss that interferes with a woman's physical, social, emotional, or material quality of life. If obstetrician-gynecologists suspect that a patient has a bleeding disorder, they should work in coordination with a hematologist for laboratory evaluation and...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000003412
更新日期：2019-09-01 00:00:00
abstract：:This study was designed to compare single-point prevalence estimates with a cumulative prevalence estimate of human papillomavirus (HPV) type 16 in cervical smears. The influence of the menstrual cycle and the long-term effect of HPV 16 positivity on the development of cervical intraepithelial neoplasia (CIN) were mon...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:The effect of noncreatinine chromogens on the endogenous creatinine clearance (ECC) during pregnancy was investigated. It was found that these chromogens measured as plasma "creatinine" cause a significant reduction in the ECC value. This fact should be considered when the ECC value is used to evaluate renal function ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1976-08-01 00:00:00
abstract：OBJECTIVE:Currently, treatment of respiratory distress syndrome (RDS) of the preterm newborn incorporates exogenous surfactant administration. Because fetuses make breathing motions, we proposed that intra-amniotic administration of an exogenous surfactant, Exosurf, to the preterm rabbit fetus results in uptake of Exos...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:Cervical pregnancy was diagnosed at 12 weeks' gestation in a young nulliparous woman presenting with vaginal bleeding. Initial treatment with methotrexate was unsuccessful. The patient was ultimately treated by internal iliac artery ligation, hysterotomy, and intracervical balloon tamponade. Nineteen months after surg...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-06-01 00:00:00
abstract：OBJECTIVES:The secreted form of ADAM12 is a metalloprotease that may be involved in placental and fetal growth. We examined whether the concentration of ADAM12 in first-trimester maternal serum could be used as a marker for preeclampsia. METHODS:We developed a semiautomated, time-resolved, immunofluorometric assay for...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000165829.65319.65
更新日期：2005-07-01 00:00:00
abstract：:Despite the use of prophylactic antibiotics, endometritis occurs in 1-31% of patients after cesarean delivery. We sought to identify predictors of prophylactic antibiotic failure. In a retrospective review of 1800 cesarean deliveries, 766 patients had either ampicillin or cefazolin prophylaxis; 240 (31.3%) developed e...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：OBJECTIVE:To describe the natural history and outcomes of a large cohort of expectantly managed angular pregnancies diagnosed in the first trimester by specific ultrasound criteria. METHODS:We conducted a prospective case series of women with prenatally diagnosed angular pregnancy at a single academic tertiary care ce...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000003595
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:To determine the serum level of macrophage colony-stimulating factor in ovarian cancer patients in order to evaluate its role as a marker for ovarian cancer. METHODS:Serum macrophage colony-stimulating factor levels were assayed in 69 patients with epithelial ovarian cancer, 55 with benign ovarian tumors, an...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：:In recognition of the 100 anniversary of women's suffrage, we reviewed the difficulties reformists overcame in passing the 19th Amendment and discuss the similarities to current challenges in providing evidence-based, affordable, accessible women's health care. Many current health care problems arise from systemic, no...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1097/AOG.0000000000004009
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:Neonatal alloimmune thrombocytopenia is caused by platelet antigen incompatibility between the mother and fetus. Affected fetuses may have severe thrombocytopenia leading to intracranial hemorrhage before or at birth. We sought to treat this condition in utero to prevent these hemorrhages. METHODS:Eighteen w...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：OBJECTIVE:To review the experience of women who conceived after developing mastocytosis and who were observed at the National Institutes of Health. METHODS:We reviewed our patient database for the years 1984-1998 to identify women with mastocytosis who had conceived. We then reviewed each woman's record, asked each wo...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(99)00591-8
更新日期：2000-03-01 00:00:00
abstract：:The increasing incidence of multiple gestations and the need for genetic diagnosis often pose a question as to the safety of amniocentesis in these cases. Under careful sonographic control and using indigo carmine as a marker, a technique for amniocentesis in a triplet gestation is presented. ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1981-09-01 00:00:00
abstract：OBJECTIVE:To evaluate weekly stripping of membranes at term to determine its safety and effectiveness in reducing the incidence of prolonged and postterm pregnancies. METHODS:One hundred forty-two pregnant women with certain gestational dates were randomly selected to receive, starting at 38 weeks, either weekly strip...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0029-7844(96)00046-4
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness and safety of an intrauterine vacuum-induced hemorrhage-control device for postpartum hemorrhage treatment. METHODS:A multicenter, prospective, single-arm treatment study of a novel intrauterine device that uses low-level vacuum to induce uterine myometrial contraction to achiev...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1097/AOG.0000000000004138
更新日期：2020-11-01 00:00:00
abstract：:Given that practice variation exists in the frequency and performance of ultrasound and magnetic resonance imaging (MRI) in pregnancy, the Eunice Kennedy Shriver National Institute of Child Health and Human Development hosted a workshop to address indications for ultrasound and MRI in pregnancy, to discuss when and ho...
journal_title：Obstetrics and gynecology
pub_type：
doi：10.1097/AOG.0000000000000245
更新日期：2014-05-01 00:00:00
abstract：:Blood samples were obtained from 5 women during the menstrual cycle in which they had conceived. Although neither the women nor their physicians were clinically aware that conception had occurred, one or more of the blood specimens from each woman contained human chorionic gonadotropin (hCG), as measured by a specific...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1977-07-01 00:00:00
abstract：:A simplified, numerical form for antepartum risk scoring was introduced as a component of the prenatal record for use in all pregancies in a large geographic area under a variety of collection practices. In a population of approximately 1,000,000 with 16,733 deliveries, 19% of the pregnant population scored greater th...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-03-01 00:00:00
abstract：:Preterm birth occurs in approximately 10% of all births in the United States and is a major contributor to perinatal morbidity and mortality (). Prelabor rupture of membranes (PROM) that occurs preterm complicates approximately 2-3% of all pregnancies in the United States, representing a significant proportion of pret...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,实务指引
doi：10.1097/AOG.0000000000003700
更新日期：2020-03-01 00:00:00
abstract：:The authors treated a 15-year-old girl with a nonfused mullerian system and absence of the cervix and vagina. Surgical reconstruction of the uterus and vagina were performed, after which menstruation first appeared. Postoperative fibrotic stenosis obliterated almost the entire vagina except for a fine uterovaginal fis...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1983-02-01 00:00:00
abstract：:When any fetal blood group factor inherited from the father is not possessed by the mother, antepartum or intrapartum fetal-maternal bleeding may stimulate an immune reaction in the mother Maternal immune reactions also can occur from blood product transfusion. The formation of maternal antibodies, or"alloimmunization...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,实务指引
doi：10.1097/00006250-200608000-00044
更新日期：2006-08-01 00:00:00
