Abstract：
OBJECTIVE:To estimate whether higher magnesium levels in umbilical cord blood at delivery are associated with increased total pediatric (fetal + neonatal + postneonatal) mortality. METHODS:During the Magnesium and Neurologic Endpoints Trial, in addition to randomizing mothers having preterm labor into arms containing magnesium sulfate, other tocolytic agents, or saline controls, we obtained biologic specimens at delivery, including umbilical cord venous blood on which was determined the serum ionized magnesium level using the AVL 988-4 analyzer (Graz, Austria). Laboratory results were then matched with the pediatric mortalities. The study power was based on the anticipated reductions in neonatal intraventricular hemorrhage related to magnesium usage from 18.9% to 4.4%. For alpha =.05, 1-beta (power)=80%, two tailed, the total number of infants needed would be 140. RESULTS:Of 149 mothers who gave permission for randomization, ionized magnesium levels were available for 82 children. Seven deaths occurred (one immediately before delivery, three as neonates, and three in the postneonatal period). The median level of ionized magnesium among the seven dead children was 0.76 mmol/L; among the 75 survivors, the median level of ionized magnesium was 0.55 mmol/L (Mann-Whitney U test, P =.03). Using multivariable logistic regression analysis, the association remained statistically significant when controlling for possible confounding factors (adjusted odds ratio 7.7, 95% confidence interval 1.2, 47.6, P =.03). CONCLUSION:These findings of a dose response between serum ionized magnesium and deaths in children increase our concern about the improper use of tocolytic magnesium.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Mittendorf R,Covert R,Elin R,Pryde PG,Khoshnood B,Lee Kdoi
10.1016/s0029-7844(01)01398-9subject
Has Abstractpub_date
2001-07-01 00:00:00pages
75-8issue
1eissn
0029-7844issn
1873-233Xpii
S0029784401013989journal_volume
98pub_type
临床试验,杂志文章,随机对照试验abstract：:Retrograde ejaculation is characterized by aspermia or oligospermia and results from an incompetent bladder neck, often due to a dysfunction of the internal sphincter. In almost 3 years, eight couples who suffered from infertility due to retrograde ejaculation were treated with inseminations with spermatozoa gained fr...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Umbilical cord blood gases were measured as objective parameters of neonatal outcome in patients delivered by Silastic vacuum extractor and were compared with those values from patients delivered spontaneously, by forceps, or by sequential use of vacuum and forceps. The results demonstrated no clinically significant d...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:A fiberoptic colposcope was converted through minor alterations into an instrument suitable for use in gynecologic microsurgery. Magnification up to 24x may be obtained, and the extreme mobility, price consideration, and reduction in space at the operating table make it an attractive alternative to a bulky, expensive ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-10-01 00:00:00
abstract：OBJECTIVE:To estimate prenatal sexually transmitted disease-human immunodeficiency virus (HIV) screening rates among insured women with prenatal care and the association of chlamydia and gonorrhea screening with Pap testing. METHODS:We estimated prenatal screening rates for syphilis, hepatitis B, HIV, chlamydia, and g...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000000756
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:Heterotopic pregnancy is a rare event in natural conception cycles. Diagnosis of heterotopic pregnancy requires a high index of suspicion. Described herein is a reported case of a heterotopic pregnancy presenting as hematometra. CASE:A young, multiparous woman, with her last menstrual period 6 weeks before ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000142698.17433.cd
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the presence of fetal fibronectin in the cervix and vagina as a screening test for spontaneous preterm birth. METHODS:Two thousand nine hundred twenty-nine women at ten centers were routinely screened every 2 weeks from 22-24 to 30 weeks for cervical and vaginal fetal fibronectin. A positive test...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,多中心研究
doi：10.1016/0029-7844(96)00035-x
更新日期：1996-05-01 00:00:00
abstract：OBJECTIVE:To establish the optimum oral daily dose of micronized medroxyprogesterone acetate, given in combination with a fixed oral dose of estrone (E1) sulfate as hormone replacement therapy, that provides endometrial protection and induces cessation of vaginal bleeding. METHODS:This multicenter, randomized, double-...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0029-7844(98)00038-6
更新日期：1998-05-01 00:00:00
abstract：:Adenocarcinoma of the vagina is an uncommon tumor. Many theories have been postulated for its etiology and tissue origin. Its occurrence in young women exposed in utero to diethylstilbestrol has pointed to estrogen influence as a possible etiologic factor. A case of adenocarcinoma of the vagina in a patient with gonad...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-03-01 00:00:00
abstract：:Unilateral jaw and ovarian Burkitt's lymphoma occuring in an adult American female is reported. The patient was treated with a combination of surgery, radiation, and chemotherapy. The diagnosis, treatment, prognosis, and relapse patterns are briefly reviewed as they relate to the specialty of gynecology. ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1976-07-01 00:00:00
abstract：OBJECTIVE:To investigate the value of the combined use of vaginal ultrasonography and endometrial sampling in the office for the diagnosis of endometrial disease in postmenopausal women. METHODS:One hundred forty consecutive postmenopausal women presenting with uterine bleeding or endometrial cells on cervical cytolog...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章
doi：10.1016/0029-7844(94)00421-9
更新日期：1995-03-01 00:00:00
abstract：BACKGROUND:Small cell carcinoma of the ovary is an aggressive tumor primarily affecting young women. Despite adjuvant therapy, the majority of patients described in the literature have fared poorly, even when the disease is diagnosed at an early stage. CASE:A 19-year-old nulligravida with small cell carcinoma of the l...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000124996.56880.d9
更新日期：2004-05-01 00:00:00
abstract：BACKGROUND:Only one case of plasma cell cervicitis, a rare variant of chronic cervicitis, has been reported. We report a second case and present data supporting the detection of human papillomavirus (HPV) outside of epithelial tissues. CASE:A 67-year-old woman was found to have a large cervical tumor. Extensive diagno...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1993-10-01 00:00:00
abstract：:Heating of metallic IUDs during ultrasound examination has been suggested as a possible hazard to surrounding tissues. Serial temperature measurements of such devices during insonation with commercially available ultrasound equipment show no temperature changes during prolonged exposure. The results indicate that the ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1978-07-01 00:00:00
abstract：:To determine whether Lamaze childbirth preparation is harmless, harmful, or beneficial, 500 consecutive Lamaze-prepared patients were compared to 500 hand-picked controls, matched for age, race, parity, and educational level. Lamaze preparation was found to have a significant beneficial effect in almost every obstetri...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1978-06-01 00:00:00
abstract：:Two hundred seven high-risk patients were studied prospectively by standardized nonstressed fetal heart rate monitoring followed immediately by contraction stress testing (CST). Of the 604 combined procedures examined, 90.2% of nonstress tests (NST) were interpreted as reactive; none was associated with a positive CST...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1980-05-01 00:00:00
abstract：OBJECTIVE:To determine whether gravidas with prior low vertical uterine incision(s) are at a higher risk for uterine rupture during a trial of labor after cesarean delivery than women with prior low transverse uterine incision(s). METHODS:The medical records of women undergoing a trial of labor after prior cesarean de...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(99)00398-1
更新日期：1999-11-01 00:00:00
abstract：OBJECTIVE:To determine whether rupture of malignant ovarian epithelial tumors at the time of operation influences the patient's overall prognosis. METHODS:Between 1975 and 1990, 79 patients with stage I invasive epithelial ovarian cancer were treated at Massachusetts General Hospital. Patients were identified from the...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：OBJECTIVE:To assess the influence of several maternal and neonatal variables on the recurrence of gestational diabetes mellitus. METHODS:A retrospective review was conducted on 90 of our patients whose index pregnancy was complicated by gestational diabetes mellitus and whose subsequent pregnancy was also managed at o...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-11-01 00:00:00
abstract：:The outcome of delivery of infants weighing more than 4000 g born during two time periods 15 years apart was studied retrospectively. The increased use of cesarean section and other obstetric advances did not reduce the risk of fetal asphyxia and trauma associated with large fetal size. Maternal factors were identifie...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1983-06-01 00:00:00
abstract：:Electrical accidents during pregnancy are relatively infrequent, and reports are rare. Six pregnant women who suffered an electrical injury during pregnancy are presented here. For all, the current path through the body was from hand to foot. Changes that occurred in fetal movements and development as well as the outc...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-198606000-00024
更新日期：1986-06-01 00:00:00
abstract：:Topical 5-fluorouracil (5-FU) has proven effective in epidermoid cancers of the head and neck. Its effectiveness has been correlated with the ability of the patient's immunologic system to recognize new antigens. In this study, 8 patients with carcinoma in situ of the vulva were evaluated and treated with topical 5-FU...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1978-06-01 00:00:00
abstract：:Mycotic cultures of 33 couples, in which the women had a diagnosis of chronic recurrent vulvovaginitis, were prepared from the oral cavity, the rectum, the vagina, and the male ejaculate. Reservoirs of infection were found in the oral cavities of 36% of the couples, the rectum in 33%, and the ejaculate in 15%. Prostat...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1987-06-01 00:00:00
abstract：:Predictors of postpartum endometritis were identified in 607 asymptomatic, laboring women. One hundred (16.5%) developed postpartum endometritis. Multivariate analysis using stepwise logistic regression identified cesarean delivery (relative risk 12.8; P less than .0001) as the dominant overall predictor. In patients ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-03-01 00:00:00
abstract：BACKGROUND:The imperforate hymen is a rare gynecologic abnormality that may not be detected until the onset of menses, when hematocolpos causes symptoms due to an expanding pelvic mass. CASE:A 19-year-old woman had primary amenorrhea, originally misdiagnosed as müllerian agenesis. Because of a combination of late onse...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：OBJECTIVE:To analyze contemporary U.S. use of minimally invasive surgery for the treatment of endometrial cancer and associated inpatient complications and costs. METHODS:In this retrospective cohort study, the National Inpatient Sample database was analyzed in patients with nonmetastatic endometrial cancer who underw...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001567
更新日期：2016-09-01 00:00:00
abstract：OBJECTIVE:To evaluate whether quality of peer review and reviewer recommendation differ based on reviewer subspecialty in obstetrics and gynecology and to determine the role of experience on reviewer recommendation. METHODS:We performed a retrospective cohort study of reviews submitted to Obstetrics & Gynecology betwe...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001852
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVES:To investigate the sensitivity of immunoblotting and enzyme-linked immunosorbent assay (ELISA) to detect autoantibodies to bullous pemphigoid antigen 180 in patients with pemphigoid gestationis and to correlate autoantibody serum levels with disease activity. METHODS:In serum samples obtained from 44 pregna...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/01.AOG.0000115506.76104.ad
更新日期：2004-04-01 00:00:00
abstract：OBJECTIVE:To assess the prevalence and causes of thrombocytopenia among full-term infants. METHODS:We conducted a 1-year, population-based surveillance study involving all full-term infants (at least 37 weeks' gestation) born to native Finnish women in Helsinki. In cases of thrombocytopenia (cord platelet count less t...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(99)00543-8
更新日期：2000-03-01 00:00:00
abstract：:This report describes an instrument to recover fertilized ova from the human uterus without anesthesia. Two hundred sixty-five lavages were performed on 20 normal and presumed fertile women and on seven infertile women. Using 60 mL of fluid, median fluid recovery was 97% (range 65-100%). In the fertile women, ova were...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-05-01 00:00:00
abstract：:The increasing incidence of multiple gestations and the need for genetic diagnosis often pose a question as to the safety of amniocentesis in these cases. Under careful sonographic control and using indigo carmine as a marker, a technique for amniocentesis in a triplet gestation is presented. ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1981-09-01 00:00:00
