Abnormal pregnancy sonogram: selective indication for fetal karyotype.

Abstract:

:The inability to make a definitive diagnosis in the fetus with a sonographically identified abnormality often results in parental and physician uncertainty. An antenatal chromosome evaluation could resolve this uncertainty. Forty-one fetuses with an abnormal ultrasound examination were tested for karyotypic abnormality using a variety of specimens. Nearly one-third (13 of 41) of these fetuses had various chromosome abnormalities. There were only seven survivors in this series, underscoring the often poor prognosis when a significant ultrasound defect is detected antenatally. Knowledge of the fetal chromosome constitution in the setting of an abnormal ultrasound has important epidemiologic, cost-benefit, counseling, and pregnancy management implications.

journal_name

Obstet Gynecol

authors

Williamson RA,Weiner CP,Patil S,Benda J,Varner MW,Abu-Yousef MM

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

15-20

issue

1

eissn

0029-7844

issn

1873-233X

journal_volume

69

pub_type

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