Genetic determinants of resistance to ectromelia (mousepox) virus-induced mortality.

abstract：:In previous reports it was demonstrated that the Nipah virus V and W proteins have interferon (IFN) antagonist activity due to their ability to block signaling from the IFN-alpha/beta receptor (J. J. Rodriguez, J. P. Parisien, and C. M. Horvath, J. Virol. 76:11476-11483, 2002; M. S. Park et al., J. Virol. 77:1501-1511...

journal_title：Journal of virology

authors： Shaw ML,García-Sastre A,Palese P,Basler CF

更新日期：2004-06-01 00:00:00

abstract：:Avian influenza virus (AIV) surveillance in Antarctica during 2013 revealed the prevalence of evolutionarily distinct influenza viruses of the H11N2 subtype in Adélie penguins. Here we present results from the continued surveillance of AIV on the Antarctic Peninsula during 2014 and 2015. In addition to the continued d...

journal_title：Journal of virology

authors： Hurt AC,Su YCF,Aban M,Peck H,Lau H,Baas C,Deng YM,Spirason N,Ellström P,Hernandez J,Olsen B,Barr IG,Vijaykrishna D,Gonzalez-Acuna D

更新日期：2016-10-14 00:00:00

abstract：:Reovirus encephalitis in mice was used as a model system to investigate astrocyte activation (astrogliosis) following viral infection of the brain. Reovirus infection resulted in astrogliosis, as evidenced by increased expression of glial fibrillary acidic protein (GFAP), and the upregulation of genes that have been p...

journal_title：Journal of virology

authors： Clarke P,Zhuang Y,Berens HM,Leser JS,Tyler KL

更新日期：2019-05-01 00:00:00

abstract：:Borna disease virus (BDV) is a neurotropic virus with a broad host and geographic range. Lewis rats were immunized against BDV with a recombinant vaccinia virus expressing the BDV nucleoprotein and were later infected with BDV to evaluate protection against Borna disease (BD). Relative to animals that were not immuniz...

journal_title：Journal of virology

authors： Lewis AJ,Whitton JL,Hatalski CG,Weissenböck H,Lipkin WI

更新日期：1999-03-01 00:00:00

abstract：:The number, chromosomal distribution, and insertional polymorphisms of endogenous feline leukemia viruses (enFeLVs) were determined in four domestic cats (Burmese, Egyptian Mau, Persian, and nonbreed) using fluorescent in situ hybridization and radiation hybrid mapping. Twenty-nine distinct enFeLV loci were detected a...

journal_title：Journal of virology

authors： Roca AL,Nash WG,Menninger JC,Murphy WJ,O'Brien SJ

更新日期：2005-04-01 00:00:00

abstract：:Passage of foot-and-mouth disease virus (FMDV) in cell culture in the presence of the mutagenic base analog 5-fluorouracil or 5-azacytidine resulted in decreases of infectivity and occasional extinction of the virus. Low viral loads and low viral fitness enhanced the frequency of extinction events; this finding was sh...

journal_title：Journal of virology

authors： Sierra S,Dávila M,Lowenstein PR,Domingo E

更新日期：2000-09-01 00:00:00

abstract：:The highly syncytium-inducing M strain and the weakly syncytium-inducing SC strain of bovine parainfluenza 3 virus differ by a single amino acid substitution in each of the hemagglutinin-neuraminidase (HN) and membrane (M) proteins, while their fusion (F) proteins are identical (T. Shioda, S. Wakao, S. Suzu, and H. Sh...

journal_title：Journal of virology

authors： Sakai Y,Shibuta H

更新日期：1989-09-01 00:00:00

abstract：UNLABELLED:An understanding of the antigen-specific B-cell response to the influenza virus hemagglutinin (HA) is critical to the development of universal influenza vaccines, but it has not been possible to examine these cells directly because HA binds to sialic acid (SA) on most cell types. Here, we use structure-based...

journal_title：Journal of virology

authors： Whittle JR,Wheatley AK,Wu L,Lingwood D,Kanekiyo M,Ma SS,Narpala SR,Yassine HM,Frank GM,Yewdell JW,Ledgerwood JE,Wei CJ,McDermott AB,Graham BS,Koup RA,Nabel GJ

更新日期：2014-04-01 00:00:00

abstract：:The nucleotide sequence of the region of human polyoma virus JC DNA between 0.5 and 0.7 map units from a unique EcoRI cleavage site was determined and compared with those of the corresponding regions of another human polyoma virus, BK, and simian virus 40 DNAs. Within this region consisting of 945 base pairs, we locat...

journal_title：Journal of virology

authors： Miyamura T,Jikuya H,Soeda E,Yoshiike K

更新日期：1983-01-01 00:00:00

abstract：:Natural killer (NK) cells derived from the human female reproductive tract (FRT) are phenotypically and functionally distinct from those obtained from peripheral blood. Because the FRT is a primary site of human immunodeficiency virus type 1 (HIV-1) infection in women, we determined whether soluble factors secreted by...

journal_title：Journal of virology

authors： Mselle TF,Howell AL,Ghosh M,Wira CR,Sentman CL

更新日期：2009-11-01 00:00:00

abstract：:10A1 murine leukemia virus can enter cells by using either of two different cell surface phosphate transport proteins, the gibbon ape leukemia virus receptor Glvr-1 (Pit-1) or the amphotropic retrovirus receptor Ram-1 (Pit-2). Glvr-1 and Ram-1 are widely expressed in different tissues, but the relative amounts of each...

journal_title：Journal of virology

authors： Miller AD,Chen F

更新日期：1996-08-01 00:00:00

abstract：:Gammaherpesvirus 68 (gammaHV68, or MHV68) is a naturally occurring rodent pathogen that replicates to high titer in cell culture and is amenable to in vivo experimental evaluation of viral and host determinants of gammaherpesvirus disease. However, the inability of MHV68 to transform primary murine B cells in culture,...

journal_title：Journal of virology

authors： Forrest JC,Speck SH

更新日期：2008-08-01 00:00:00

abstract：:The infection of human fetal thymus organ cultures (FTOC) with coxsackievirus B4 E2 (CVB4 E2) was investigated. Both positive- and negative-strand viral RNA were detected by real-time quantitative reverse transcription-PCR (RT-PCR) in CVB4 E2-infected FTOC, which supported high yields of virus production (approximatel...

journal_title：Journal of virology

authors： Brilot F,Geenen V,Hober D,Stoddart CA

更新日期：2004-09-01 00:00:00

abstract：:Murine leukemia viruses isolated from radiation-induced BALB/c leukemias were characterized with respect to viral proteins and RNA. Analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis of the viral structural proteins revealed that for p12, p15, p30, and gp70, three of four electrophoretic variants of...

journal_title：Journal of virology

authors： Ellis RW,Hopkins N,Fleissner E

更新日期：1980-02-01 00:00:00

abstract：:The phenotypes of a series of mutant human immunodeficiency virus type 1 proviruses with linker insertion and deletion mutations within the gag coding region were characterized. These mutants, with mutations in the matrix, capsid, and p2 coding regions, produced replication-defective virion particles with defects in t...

journal_title：Journal of virology

authors： Reicin AS,Ohagen A,Yin L,Hoglund S,Goff SP

更新日期：1996-12-01 00:00:00

abstract：:The in vitro transcription pattern of simian virus 40 (SV40) deoxyribonucleic acid (DNA) by a mammalian ribonucleic acid (RNA) polymerase, was studied by electron microscopy and velocity sedimentation techniques. It was found that (i) the majority of supercoiled SV40 DNA molecules displayed a single binding site for t...

journal_title：Journal of virology

authors： Herzberg M,Winocour E

更新日期：1970-11-01 00:00:00

abstract：:Signal transducers and activators of transcription (STATs) relay signals from activated cell surface receptors directly to the nucleus. Previously, a protein required for T-cell transformation by the DNA tumor virus herpesvirus saimiri (HVS) and designated tyrosine kinase interacting protein (Tip-484) was shown to int...

journal_title：Journal of virology

authors： Lund TC,Garcia R,Medveczky MM,Jove R,Medveczky PG

更新日期：1997-09-01 00:00:00

abstract：:To assess the role of naturally occurring basic amino acid substitutions in the V3 loop of human immunodeficiency virus type 1 (HIV-1) subtype E on viral coreceptor usage and cell tropism, we have constructed a panel of chimeric viruses with mutant V3 loops of HIV-1 subtype E in the genetic background of HIV-1LAI. The...

journal_title：Journal of virology

authors： Kato K,Sato H,Takebe Y

更新日期：1999-07-01 00:00:00

abstract：:Synthesis of the vesicular stomatitis virus membrane matrix protein and the glycoprotein is inhibited to a greater extent than the synthesis of the nucleocapsid protein, the nonstructural protein, and the large protein when the rate of peptide chain initiation is reduced by exposure of vesicular stomatitis virus-infec...

journal_title：Journal of virology

authors： Nuss DL,Koch G

更新日期：1975-01-01 00:00:00

abstract：:Hepatitis B virus (HBV) DNA clones were propagated from 57 carriers with antibody to hepatitis B e antigen (HBeAg) and sequenced within nucleotides (nt) 1685 to 1926 including the core promoter (nt 1742 to 1849) and the pre-C region (nt 1814 to 1900). Mutations in the core promoter or those in the pre-C region, or bot...

journal_title：Journal of virology

authors： Okamoto H,Tsuda F,Akahane Y,Sugai Y,Yoshiba M,Moriyama K,Tanaka T,Miyakawa Y,Mayumi M

更新日期：1994-12-01 00:00:00

abstract：:The E6 oncoproteins encoded by the cancer-associated human papillomaviruses (HPVs) can associate with and promote the degradation of wild-type p53 in vitro. To gain further insight into this process, the ability of HPV-16 E6 to complex with and promote the degradation of mutant forms of p53 was studied. A correlation ...

journal_title：Journal of virology

authors： Scheffner M,Takahashi T,Huibregtse JM,Minna JD,Howley PM

更新日期：1992-08-01 00:00:00

abstract：:Structural proteins designated p10gag, p21gag, p8gag, p3gag, p27gag, and p14gag from the C3H strain of mouse mammary tumor virus (MMTV) were purified by reversed-phase high-pressure liquid chromatography. The N- and C-terminal amino acid sequences and amino acid composition of each protein were determined and compared...

journal_title：Journal of virology

authors： Hizi A,Henderson LE,Copeland TD,Sowder RC,Krutzsch HC,Oroszlan S

更新日期：1989-06-01 00:00:00

abstract：:The vif gene of human immunodeficiency virus type 1 (HIV-1) encodes a basic Mr 23,000 protein that is necessary for production of infectious virions by nonpermissive cells (human lymphocytes and macrophages) but not by permissive cells such as HeLa-CD4. It had been proposed that permissive cells may contain an unident...

journal_title：Journal of virology

authors： Madani N,Kabat D

更新日期：1998-12-01 00:00:00

abstract：:During paramyxovirus entry into a host cell, receptor engagement by a specialized binding protein triggers conformational changes in the adjacent fusion protein (F), leading to fusion between the viral and cell membranes. According to the existing paradigm of paramyxovirus membrane fusion, the initial activation of F ...

journal_title：Journal of virology

authors： Porotto M,Devito I,Palmer SG,Jurgens EM,Yee JL,Yokoyama CC,Pessi A,Moscona A

更新日期：2011-12-01 00:00:00

abstract：:Influenza pandemic preparedness has focused on influenza virus H5 and H7 subtypes. However, it is not possible to predict with certainty which subtype of avian influenza virus will cause the next pandemic, and it is prudent to include other avian influenza virus subtypes in pandemic preparedness efforts. An H6 influen...

journal_title：Journal of virology

authors： Gillim-Ross L,Santos C,Chen Z,Aspelund A,Yang CF,Ye D,Jin H,Kemble G,Subbarao K

更新日期：2008-11-01 00:00:00

abstract：:It has previously been shown that: (i) during infection of its host, the DNA bacteriophage T7 assembles a DNA-free procapsid (capsid I), a capsid with an envelope differing physically and chemically from the capsid of the mature bacteriophage, and (ii) capsid I converts to a capsid (capsid II) with a bacteriophage-lik...

journal_title：Journal of virology

authors： Serwer P,Watson RH,Hayes SJ

更新日期：1982-05-01 00:00:00

abstract：:Adeno-associated virus (AAV) integrates very efficiently into a specific site (AAVS1) of human chromosome 19. Two elements of the AAV genome are sufficient: the inverted terminal repeats (ITRs) and the Rep78 or Rep68 protein. The incorporation of the AAV integration machinery in nonviral delivery systems is of great i...

journal_title：Journal of virology

authors： Lamartina S,Roscilli G,Rinaudo D,Delmastro P,Toniatti C

更新日期：1998-09-01 00:00:00

abstract：:The C-type lectins DC-SIGN and DC-SIGNR [collectively referred to as DC-SIGN(R)] bind and transmit human immunodeficiency virus (HIV) and simian immunodeficiency virus to T cells via the viral envelope glycoprotein (Env). Other viruses containing heavily glycosylated glycoproteins (GPs) fail to interact with DC-SIGN(R...

journal_title：Journal of virology

authors： Lin G,Simmons G,Pöhlmann S,Baribaud F,Ni H,Leslie GJ,Haggarty BS,Bates P,Weissman D,Hoxie JA,Doms RW

更新日期：2003-01-01 00:00:00

abstract：:We analyzed the CD4+ T-lymphocyte responses to dengue, West Nile, and yellow fever viruses 4 months after immunization of a volunteer with an experimental live-attenuated dengue virus type 1 vaccine (DEN-1 45AZ5). We examined bulk culture proliferation to noninfectious antigens, determined the precursor frequency of s...

journal_title：Journal of virology

authors： Green S,Kurane I,Edelman R,Tacket CO,Eckels KH,Vaughn DW,Hoke CH Jr,Ennis FA

更新日期：1993-10-01 00:00:00

abstract：:Infection of the central nervous system (CNS) by several viruses can lead to upregulation of proinflammatory cytokines and chemokines. In immunocompetent adults, these molecules induce prominent inflammatory infiltrates. However, with immunosuppressive retroviruses, such as human immunodeficiency virus (HIV), little C...

journal_title：Journal of virology

authors： Peterson KE,Robertson SJ,Portis JL,Chesebro B

更新日期：2001-03-01 00:00:00