A stratospheric pathway linking a colder Siberia to Barents-Kara Sea sea ice loss.

abstract：:Dynamic nuclear polarization (DNP) is an important technique that uses polarization transfer from electron to nuclear spins to achieve nuclear hyperpolarization. Combining efficient DNP with optically polarized nitrogen-vacancy (NV) centers offers promising opportunities for novel technological applications, including...

journal_title：Science advances

authors： Schwartz I,Scheuer J,Tratzmiller B,Müller S,Chen Q,Dhand I,Wang ZY,Müller C,Naydenov B,Jelezko F,Plenio MB

更新日期：2018-08-31 00:00:00

abstract：:Revealing physical interactions in complex systems from observed collective dynamics constitutes a fundamental inverse problem in science. Current reconstruction methods require access to a system's model or dynamical data at a level of detail often not available. We exploit changes in invariant measures, in particula...

journal_title：Science advances

authors： Nitzan M,Casadiego J,Timme M

更新日期：2017-02-10 00:00:00

abstract：:Cell chirality is a newly discovered intrinsic property of the cell, reflecting the bias of the cell to polarize in the left-right axis. Despite increasing evidence on its substantial role in the asymmetric development of embryos, little is known about implications of cell chirality in physiology and disease. We demon...

journal_title：Science advances

authors： Fan J,Ray P,Lu YW,Kaur G,Schwarz JJ,Wan LQ

更新日期：2018-10-24 00:00:00

abstract：:Human genome-wide association studies have linked single-nucleotide polymorphisms (SNPs) in NEMP1 (nuclear envelope membrane protein 1) with early menopause; however, it is unclear whether NEMP1 has any role in fertility. We show that whole-animal loss of NEMP1 homologs in Drosophila, Caenorhabditis elegans, zebrafish...

journal_title：Science advances

authors： Tsatskis Y,Rosenfeld R,Pearson JD,Boswell C,Qu Y,Kim K,Fabian L,Mohammad A,Wang X,Robson MI,Krchma K,Wu J,Gonçalves J,Hodzic D,Wu S,Potter D,Pelletier L,Dunham WH,Gingras AC,Sun Y,Meng J,Godt D,Schedl T,Ciru

更新日期：2020-08-28 00:00:00

abstract：:Dirac materials such as graphene and topological insulators (TIs) are known to have unique electronic and spintronic properties. We combine graphene with TIs in van der Waals heterostructures to demonstrate the emergence of a strong proximity-induced spin-orbit coupling in graphene. By performing spin transport and pr...

journal_title：Science advances

authors： Khokhriakov D,Cummings AW,Song K,Vila M,Karpiak B,Dankert A,Roche S,Dash SP

更新日期：2018-09-21 00:00:00

abstract：:The pathways and transformations of dense water overflows, which depend on small-scale interactions between flow dynamics and erosional-depositional processes, are a central piece in the ocean's large-scale circulation. A novel, high-resolution current and hydrographic data set highlights the intricate pathway travell...

journal_title：Science advances

authors： Sánchez-Leal RF,Bellanco MJ,Fernández-Salas LM,García-Lafuente J,Gasser-Rubinat M,González-Pola C,Hernández-Molina FJ,Pelegrí JL,Peliz A,Relvas P,Roque D,Ruiz-Villarreal M,Sammartino S,Sánchez-Garrido JC

更新日期：2017-11-15 00:00:00

abstract：:l-DOPA treatment for Parkinson's disease frequently leads to dyskinesias, the pathophysiology of which is poorly understood. We used MALDI-MSI to map the distribution of l-DOPA and monoaminergic pathways in brains of dyskinetic and nondyskinetic primates. We report elevated levels of l-DOPA, and its metabolite 3-O-met...

journal_title：Science advances

authors： Fridjonsdottir E,Shariatgorji R,Nilsson A,Vallianatou T,Odell LR,Schembri LS,Svenningsson P,Fernagut PO,Crossman AR,Bezard E,Andrén PE

更新日期：2021-01-06 00:00:00

abstract：:The hydrogen atom-the smallest and most abundant atom-is of utmost importance in physics and chemistry. Although many analysis methods have been applied to its study, direct observation of hydrogen atoms in a single molecule remains largely unexplored. We use atomic force microscopy (AFM) to resolve the outermost hydr...

journal_title：Science advances

authors： Kawai S,Nishiuchi T,Kodama T,Spijker P,Pawlak R,Meier T,Tracey J,Kubo T,Meyer E,Foster AS

更新日期：2017-05-12 00:00:00

abstract：:Ciliary oscillations driven by molecular motors cause fluid motion at micron scale. Stable oscillations require a substantial source of dissipation to balance the energy input of motors. Conventionally, it stems from external fluid. We show, in contrast, that external fluid friction is negligible compared to internal ...

journal_title：Science advances

authors： Mondal D,Adhikari R,Sharma P

更新日期：2020-08-12 00:00:00

abstract：:Cytosolic RNA sensing is a prerequisite for initiation of innate immune response against RNA viral pathogens. Signaling through RIG-I (retinoic acid-inducible gene I)-like receptors (RLRs) to TBK1 (Tank-binding kinase 1)/IKKε (IκB kinase ε) kinases is transduced by mitochondria-associated MAVS (mitochondrial antiviral...

journal_title：Science advances

authors： Xiang W,Zhang Q,Lin X,Wu S,Zhou Y,Meng F,Fan Y,Shen T,Xiao M,Xia Z,Zou J,Feng XH,Xu P

更新日期：2016-07-01 00:00:00

abstract：:Black phosphorus quantum dots (BPQDs) are proposed as effective seed-like sites to modulate the nucleation and growth of CsPbI2Br perovskite crystalline thin layers, allowing an enhanced crystallization and remarkable morphological improvement. We reveal that the lone-pair electrons of BPQDs can induce strong binding ...

journal_title：Science advances

authors： Gong X,Guan L,Li Q,Li Y,Zhang T,Pan H,Sun Q,Shen Y,Grätzel C,Zakeeruddin SM,Grätzel M,Wang M

更新日期：2020-04-10 00:00:00

abstract：:Quantum phenomena have the potential to speed up the solution of hard optimization problems. For example, quantum annealing, based on the quantum tunneling effect, has recently been shown to scale exponentially better with system size than classical simulated annealing. However, current realizations of quantum anneale...

journal_title：Science advances

authors： Nigg SE,Lörch N,Tiwari RP

更新日期：2017-04-07 00:00:00

abstract：:The first example of a homogeneous silver(I)-catalyzed aerobic oxidation of aldehydes in water is reported. More than 50 examples of different aliphatic and aromatic aldehydes, including natural products, were tested, and all of them successfully underwent aerobic oxidation to give the corresponding carboxylic acids i...

journal_title：Science advances

authors： Liu M,Wang H,Zeng H,Li CJ

更新日期：2015-03-27 00:00:00

abstract：:Viscosity of fluids is strongly system dependent, varies across many orders of magnitude, and depends on molecular interactions and structure in a complex way not amenable to first-principles theories. Despite the variations and theoretical difficulties, we find a new quantity setting the minimal kinematic viscosity o...

journal_title：Science advances

authors： Trachenko K,Brazhkin VV

更新日期：2020-04-24 00:00:00

abstract：:While the ecological impacts of fishing the waters beyond national jurisdiction (the "high seas") have been widely studied, the economic rationale is more difficult to ascertain because of scarce data on the costs and revenues of the fleets that fish there. Newly compiled satellite data and machine learning now allow ...

journal_title：Science advances

authors： Sala E,Mayorga J,Costello C,Kroodsma D,Palomares MLD,Pauly D,Sumaila UR,Zeller D

更新日期：2018-06-06 00:00:00

abstract：:Fluid commonly flows in response to an external pressure gradient. However, when a tunnel-containing hydrogel is immersed in water, spontaneous flow occurs through the tunnel without any pressure gradient. We confirmed this flow in a wide range of plant- and animal-derived hydrogels. The flow appears to be driven by a...

journal_title：Science advances

authors： Li Z,Pollack GH

更新日期：2020-05-08 00:00:00

abstract：:Six percent of Americans, including 3 million high schoolers, use e-cigarettes, which contain potentially toxic substances, volatile organic compounds, and metals. We present the first human study on the effects of e-cigarette exposure in the oral cavity. By interrogating both immunoinflammatory responses and microbia...

journal_title：Science advances

authors： Ganesan SM,Dabdoub SM,Nagaraja HN,Scott ML,Pamulapati S,Berman ML,Shields PG,Wewers ME,Kumar PS

更新日期：2020-05-27 00:00:00

abstract：:Maternal immune activation increases the risk of neurodevelopmental disorders. Elevated cytokines, such as interferon-γ (IFN-γ), in offspring's brains play a central role. IFN-γ activates an antiviral cellular state, limiting viral entry and replication. Moreover, IFN-γ is implicated in brain development. We tested th...

journal_title：Science advances

authors： Warre-Cornish K,Perfect L,Nagy R,Duarte RRR,Reid MJ,Raval P,Mueller A,Evans AL,Couch A,Ghevaert C,McAlonan G,Loth E,Murphy D,Powell TR,Vernon AC,Srivastava DP,Price J

更新日期：2020-08-19 00:00:00

abstract：:Self-assembly of colloidal nanocrystals into complex superstructures offers notable opportunities to create functional devices and artificial materials with unusual properties. Anisotropic nanoparticles with nonspherical shapes, such as rods, plates, polyhedra, and multipods, enable the formation of a diverse range of...

journal_title：Science advances

authors： Wang Q,Wang Z,Li Z,Xiao J,Shan H,Fang Z,Qi L

更新日期：2017-10-27 00:00:00

abstract：:Changes in CO2 emissions during the COVID-19 pandemic have been estimated from indicators on activities like transportation and electricity generation. Here, we instead use satellite observations together with bottom-up information to track the daily dynamics of CO2 emissions during the pandemic. Unlike activity data,...

journal_title：Science advances

authors： Zheng B,Geng G,Ciais P,Davis SJ,Martin RV,Meng J,Wu N,Chevallier F,Broquet G,Boersma F,van der A R,Lin J,Guan D,Lei Y,He K,Zhang Q

更新日期：2020-12-02 00:00:00

abstract：:The Mott metal-insulator transition, a paradigm of strong electron-electron correlations, has been considered as a source of intriguing phenomena. Despite its importance for a wide range of materials, fundamental aspects of the transition, such as its universal properties, are still under debate. We report detailed me...

journal_title：Science advances

authors： Gati E,Garst M,Manna RS,Tutsch U,Wolf B,Bartosch L,Schubert H,Sasaki T,Schlueter JA,Lang M

更新日期：2016-12-07 00:00:00

abstract：:Peripheral blood mononuclear cells (PBMCs) may provide insight into the pathogenesis of Alzheimer's disease (AD) or Parkinson's disease (PD). We investigated PBMC samples from 132 well-characterized research participants using seven canonical immune stimulants, mass cytometric identification of 35 PBMC subsets, and si...

journal_title：Science advances

authors： Phongpreecha T,Fernandez R,Mrdjen D,Culos A,Gajera CR,Wawro AM,Stanley N,Gaudilliere B,Poston KL,Aghaeepour N,Montine TJ

更新日期：2020-11-25 00:00:00

abstract：:Human and murine skin wounding commonly results in fibrotic scarring, but the murine wounding model wound-induced hair neogenesis (WIHN) can frequently result in a regenerative repair response. Here, we show in single-cell RNA sequencing comparisons of semi-regenerative and fibrotic WIHN wounds, increased expression o...

journal_title：Science advances

authors： Gay D,Ghinatti G,Guerrero-Juarez CF,Ferrer RA,Ferri F,Lim CH,Murakami S,Gault N,Barroca V,Rombeau I,Mauffrey P,Irbah L,Treffeisen E,Franz S,Boissonnas A,Combadière C,Ito M,Plikus MV,Romeo PH

更新日期：2020-03-20 00:00:00

abstract：:The importance of comets for the origin of life on Earth has been advocated for many decades. Amino acids are key ingredients in chemistry, leading to life as we know it. Many primitive meteorites contain amino acids, and it is generally believed that these are formed by aqueous alterations. In the collector aerogel a...

journal_title：Science advances

authors： Altwegg K,Balsiger H,Bar-Nun A,Berthelier JJ,Bieler A,Bochsler P,Briois C,Calmonte U,Combi MR,Cottin H,De Keyser J,Dhooghe F,Fiethe B,Fuselier SA,Gasc S,Gombosi TI,Hansen KC,Haessig M,Jäckel A,Kopp E,Korth A,Le

更新日期：2016-05-27 00:00:00

abstract：:There have been increasing attempts to reverse habitat degradation through active restoration, but few large-scale successes are reported to guide these efforts. Here, we report outcomes from a unique and very successful seagrass restoration project: Since 1999, over 70 million seeds of a marine angiosperm, eelgrass (...

journal_title：Science advances

authors： Orth RJ,Lefcheck JS,McGlathery KS,Aoki L,Luckenbach MW,Moore KA,Oreska MPJ,Snyder R,Wilcox DJ,Lusk B

更新日期：2020-10-07 00:00:00

abstract：:Demyelinating diseases involve loss of myelin sheaths and eventually lead to neurological problems. Unfortunately, the precise mechanisms remain unknown, and there are no effective therapies. To overcome these limitations, a reliable and physiologically relevant in vitro model is required. Here, we present a three-dim...

journal_title：Science advances

authors： Hyung S,Lee SR,Kim J,Kim Y,Kim S,Kim HN,Jeon NL

更新日期：2021-01-29 00:00:00

abstract：:The formation of the Isthmus of Panama stands as one of the greatest natural events of the Cenozoic, driving profound biotic transformations on land and in the oceans. Some recent studies suggest that the Isthmus formed many millions of years earlier than the widely recognized age of approximately 3 million years ago ...

journal_title：Science advances

authors： O'Dea A,Lessios HA,Coates AG,Eytan RI,Restrepo-Moreno SA,Cione AL,Collins LS,de Queiroz A,Farris DW,Norris RD,Stallard RF,Woodburne MO,Aguilera O,Aubry MP,Berggren WA,Budd AF,Cozzuol MA,Coppard SE,Duque-Caro H,Finne

更新日期：2016-08-17 00:00:00

abstract：:Using theory and experiments, we study the interface between two immiscible domains in a colloidal membrane composed of rigid rods of different lengths. Geometric considerations of rigid rod packing imply that a domain of sufficiently short rods in a background membrane of long rods is more susceptible to twist than t...

journal_title：Science advances

authors： Miller JM,Hall D,Robaszewski J,Sharma P,Hagan MF,Grason GM,Dogic Z

更新日期：2020-07-29 00:00:00

abstract：:The Late Paleogene surface height and paleoenvironment for the core area of the Qinghai-Tibetan Plateau (QTP) remain critically unresolved. Here, we report the discovery of the youngest well-preserved fossil palm leaves from Tibet. They were recovered from the Late Paleogene (Chattian), ca. 25.5 ± 0.5 million years, p...

journal_title：Science advances

authors： Su T,Farnsworth A,Spicer RA,Huang J,Wu FX,Liu J,Li SF,Xing YW,Huang YJ,Deng WY,Tang H,Xu CL,Zhao F,Srivastava G,Valdes PJ,Deng T,Zhou ZK

更新日期：2019-03-06 00:00:00

abstract：:Membrane proteins must balance the sequence constraints associated with folding and function against the hydrophobicity required for solvation within the bilayer. We recently found the expression and maturation of rhodopsin are limited by the hydrophobicity of its seventh transmembrane domain (TM7), which contains pol...

journal_title：Science advances

authors： Penn WD,McKee AG,Kuntz CP,Woods H,Nash V,Gruenhagen TC,Roushar FJ,Chandak M,Hemmerich C,Rusch DB,Meiler J,Schlebach JP

更新日期：2020-03-04 00:00:00