The skewed frequency of B-cell subpopulation CD19+ CD24 hi CD38 hi cells in peripheral blood mononuclear cells is correlated with the elevated serum sCD40L in patients with active systemic lupus erythematosus.

abstract：:The bone marrow stroma contains pre-adipocyte cells which are part of the hemopoietic microenvironment. Cloned stromal cell lines differ both in their ability to support myeloid and lymphoid development and in their ability to undergo adipocyte differentiation in vitro. These processes have been examined in the +/+2.4...

journal_title：Journal of cellular biochemistry

authors： Gimble JM,Youkhana K,Hua X,Bass H,Medina K,Sullivan M,Greenberger J,Wang CS

更新日期：1992-09-01 00:00:00

abstract：:We characterized a human cDNA clone encoding a 36-kDa carboxyl terminal LIM domain protein with a PDZ domain at the amino terminal. This full-length cDNA clone has a predicted open reading frame (ORF) of 329 amino-acid residues. The ORF of this cDNA encodes the human homolog of rat CLP36, and the putative protein is n...

journal_title：Journal of cellular biochemistry

authors： Kotaka M,Ngai SM,Garcia-Barcelo M,Tsui SK,Fung KP,Lee CY,Waye MM

更新日期：1999-02-01 00:00:00

abstract：:Nowadays, increased use of nanomaterials in industry and biomedicine poses potential risks to human health and the environment. Studying their possible toxicological effects is therefore of great significance. The present investigation was designed to examine the status of oxidative stress induced by nanoparticles (NP...

journal_title：Journal of cellular biochemistry

authors： Soltani A,Kahkhaie KR,Haftcheshmeh SM,Jalali Nezhad AA,Akbar Boojar MM

更新日期：2018-11-28 00:00:00

abstract：:Gastric cancer (GC) is the fourth common cancer and second leading cause of cancer-related mortality in the world. WD repeat domain 5 (WDR5) has been identified that its functions as an important role in various biological functions through the epigenetic regulation of gene transcription. However, the oncogenic effect...

journal_title：Journal of cellular biochemistry

authors： Sun W,Guo F,Liu M

更新日期：2018-04-01 00:00:00

abstract：:In a previous study, we have shown that the gene promoter of a protein termed KIAA0082 is regulated by interferon and that this protein interacts with the RNA polymerase II. It has been subsequently shown that KIAA0082 is the human cap-specific messenger RNA (mRNA) (nucleoside-2'-O-)-methyltransferase 1 (hMTr1), which...

journal_title：Journal of cellular biochemistry

authors： Simabuco FM,Pavan ICB,Pestana NF,Carvalho PC,Basei FL,Campos Granato D,Paes Leme AF,Zanchin NIT

更新日期：2019-04-01 00:00:00

abstract：:Hepatitis C virus (HCV) is the most prevalent viral pathogen that infects more than 185 million people worldwide. HCV infection leads to chronic liver diseases such as liver cirrhosis and hepatocellular carcinoma. Direct-acting antivirals (DAAs) are the recent combination therapy for HCV infection with reduced side ef...

journal_title：Journal of cellular biochemistry

authors： Venkatesan A,Prabhu Dass J F

更新日期：2019-08-01 00:00:00

abstract：:The cardiomyocyte differentiation from mouse embryonic stem cells (mESCs) is a dynamic and complex process that involved in the precision regulation of histone acetylation. The formation of action potential (AP) in mature cardiomyocytes is based on the expression pattern of Na+ , Ca2+ , and K+ ion channels, in which t...

journal_title：Journal of cellular biochemistry

authors： Wang D,Liu C,Li Z,Wang Y,Wang W,Wu X,Wang K,Miao W,Li L,Peng L

更新日期：2017-12-01 00:00:00

abstract：:Lung cancer is the leading cause of death among all cancers. Non-small cell lung cancer accounts for 80% of lung cancer with a 5-year survival rate of 16%. Notch pathway, especially Notch-1 is up-regulated in a subgroup of non-small cell lung cancer patients. Since Notch-1 signaling plays an important role in cell pro...

journal_title：Journal of cellular biochemistry

authors： Ji X,Wang Z,Geamanu A,Sarkar FH,Gupta SV

更新日期：2011-10-01 00:00:00

abstract：:The expression of receptors belonging to the epidermal growth factor receptor subfamily has been largely studied these last years in epithelial cells mainly as involved in cell proliferation and malignant progression. Although much work has focused on the role of these growth factor receptors in the differentiation of...

journal_title：Journal of cellular biochemistry

authors： Pagano E,Calvo JC

更新日期：2003-10-15 00:00:00

abstract：:Mesenchymal stem cells (MSCs) play an important role in regulating angiogenesis and immune balance. The abnormal MSCs in proliferation and function were reported at maternal fetal interface in patients with pre-eclampsia (PE). Long non-coding RNA MALAT1 was known to regulate the function of trophoblast cells. However,...

journal_title：Journal of cellular biochemistry

authors： Li X,Song Y,Liu F,Liu D,Miao H,Ren J,Xu J,Ding L,Hu Y,Wang Z,Hou Y,Zhao G

更新日期：2017-09-01 00:00:00

abstract：:Focal adhesion kinase (FAK) is a structurally unique nonreceptor protein-tyrosine kinase that localizes to focal adhesion plaques. Regulation of its activity has been implicated in diverse signaling pathways, including those mediated by extracellular matrix/integrin interactions, G-protein coupled receptors for mitoge...

journal_title：Journal of cellular biochemistry

authors： Polte TR,Naftilan AJ,Hanks SK

更新日期：1994-05-01 00:00:00

abstract：:Pristimerin is a natural product derived from the Celastraceae and Hippocrateaceae families that were used as folk medicines for anti inflammation in ancient times. Although it has been shown that pristimerin induces apoptosis in breast cancer cells, the involved mechanism of action is unknown. The purpose of the curr...

journal_title：Journal of cellular biochemistry

authors： Yang H,Landis-Piwowar KR,Lu D,Yuan P,Li L,Reddy GP,Yuan X,Dou QP

更新日期：2008-01-01 00:00:00

abstract：:Diabetes mellitus has been related with an increased risk of breast cancer, whereas it has been suggested that links between diabetes mellitus and cancer are hyperinsulinemia, insulin resistance, hyperglycemia, and chronic inflammation induced by adipose tissue. Contribution of hyperinsulinemia to carcinogenesis is me...

journal_title：Journal of cellular biochemistry

authors： Rodriguez-Monterrosas C,Díaz-Aragon R,Leal-Orta E,Cortes-Reynosa P,Perez Salazar E

更新日期：2018-05-01 00:00:00

abstract：:Extracts of serum-free conditioned medium from human rhabdomyosarcoma A673 cells contain high molecular weight (HMW) transforming growth factors (TGFs) that can be partially purified by Bio-Gel P-100 and carboxymethyl (CM)-cellulose chromatography (Todaro et al: Proc Natl Acad Sci USA 77:5258, 1980). Reverse-phase hig...

journal_title：Journal of cellular biochemistry

authors： Stromberg K,Hudgins WR,Fryling CM,Hazarika P,Dedman JR,Pardue RL,Hargreaves WR,Orth DN

更新日期：1986-01-01 00:00:00

abstract：:Prostate cancer is the second highest caused by cancer-related death among males. microRNAs (miRs) have been reported to participate in carcinogenesis, yet their roles in prostate cancer are rarely studied or investigated. Therefore, the present study attempted to explore the effect of miR-137 in prostate cancer via r...

journal_title：Journal of cellular biochemistry

authors： Wu QQ,Zheng B,Weng GB,Yang HM,Ren Y,Weng XJ,Zhang SW,Zhu WZ

更新日期：2019-06-01 00:00:00

abstract：:The lysosomal cysteine protease cathepsin B is implicated in degradation of extracellular matrix (ECM), a crucial step in a variety of physiological and pathological processes, including tumor dissemination and angiogenesis. In this study, we analyzed the contribution of extracellular and intracellular cathepsin B act...

journal_title：Journal of cellular biochemistry

authors： Premzl A,Turk V,Kos J

更新日期：2006-04-15 00:00:00

abstract：:Endothelins (ETs) are vasoconstrictive peptides produced mainly by endothelial cells. The ET receptors are expressed in many types of cells including osteoblast-like cells. The purpose of this study was to examine the effects of endothelin on the expression of osteoblastic phenotype-related genes. We found that endoth...

journal_title：Journal of cellular biochemistry

authors： Shioide M,Noda M

更新日期：1993-10-01 00:00:00

abstract：:The receptor for epidermal growth factor (EGF) is a glycosylated transmembrane phosphoprotein that exhibits EGF-stimulable protein tyrosine kinase activity. On EGF stimulation, the receptor undergoes a self-phosphorylation reaction at tyrosine residues located primarily in the extreme carboxyl-terminal region of the p...

journal_title：Journal of cellular biochemistry

authors： Bertics PJ,Weber W,Cochet C,Gill GN

更新日期：1985-01-01 00:00:00

abstract：:We have examined the concept of genomic instability in relation to the metastatic progression of low (F1) and high metastasis (BL6, ML8) clones of the B16 mouse melanoma, by using a mutation assay, and DNA strand break repair and repair fidelity assays. The frequency of induced ouabain resistant colonies between the v...

journal_title：Journal of cellular biochemistry

authors： Usmani BA,Lunec J,Sherbet GV

更新日期：1993-03-01 00:00:00

abstract：:This study aimed to identify differential circular RNA (circRNA) in the plasma exosomes of patients with lung adenocarcinoma (LUAD) using high-throughput sequencing. First, exosomes were isolated using an exosome isolation kit and confirmed by Western blotting, transmission electron microscopy, and NanoSight Assay. Su...

journal_title：Journal of cellular biochemistry

authors： Chen F,Huang C,Wu Q,Jiang L,Chen S,Chen L

更新日期：2020-03-01 00:00:00

abstract：:The mammalian target of rapamycin (mTOR) pathway is dysregulated in more than 50% of all human malignancies and is a major target in cancer treatment. In this study, we explored the underlying mechanism involving microRNA-145-3p (miR-145-3p) in the development and progression of non-small cell lung cancer (NSCLC) by t...

journal_title：Journal of cellular biochemistry

authors： Chen GM,Zheng AJ,Cai J,Han P,Ji HB,Wang LL

更新日期：2018-01-01 00:00:00

abstract：:Endogenous peptides play crucial roles in various biological processes. Their effects on the pathogenesis of human infantile hemangioma remains poorly understood. In this study, we construct a comparative peptidomic profiling between human infantile hemangioma tissue and matched normal skin using liquid chromatography...

journal_title：Journal of cellular biochemistry

authors： Li Q,Li J,Chen L,Gao Y,Li J

更新日期：2018-06-01 00:00:00

abstract：:Angiogenesis, the formation of new capillary blood vessels, occurs almost exclusively in the microcirculation. This process is controlled by the interaction between factors with positive and negative regulatory activity. In this study, we have compared the effect of two well described positive regulators, vascular end...

journal_title：Journal of cellular biochemistry

authors： Cavallaro U,Tenan M,Castelli V,Perilli A,Maggiano N,Van Meir EG,Montesano R,Soria MR,Pepper MS

更新日期：2001-01-01 00:00:00

abstract：:From the mouse JB6 epidermal cell line C122 we have isolated a cDNA clone representing a 1.6-kilobase mRNA, called 2ar, that exhibits a biphasic induction in response to 12-O-tetradecanoyl-phorbol-13-acetate (TPA). The first phase of induction in subconfluent cells is transient, peaking at 6 h after the addition of TP...

journal_title：Journal of cellular biochemistry

authors： Smith JH,Denhardt DT

更新日期：1987-05-01 00:00:00

abstract：:We investigated the early effects of the anti-idiotypic antibody (clone 1D5), which recognized the estrogen receptor (ER), on cytosolic free calcium concentration ([Ca2+]i) and its long term effects on creatine kinase (CK) specific activity in female human and rat osteoblasts. These actions were compared to the known ...

journal_title：Journal of cellular biochemistry

authors： Sömjen D,Kohen F,Lieberherr M

更新日期：1997-04-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC) is one of the malignant type of breast cancer. Previous study indicated that long noncoding RNA (lncRNA) ZEB1-AS1 was associated with the progression of several cancers. However, its underlying molecular mechanism in TNBC remains to be elucidated. In this study, ZEB1-AS1 expression...

journal_title：Journal of cellular biochemistry

authors： Luo N,Zhang K,Li X,Hu Y

更新日期：2020-10-01 00:00:00

abstract：:Small for gestational age (SGA) has a high risk of mortality and morbidity and is common in obstetrics. To date, no effective prediction and treatment tools are available. Acting as microRNA (miRNA) sponges and disease biomarkers are clear functions of circular RNAs (circRNAs). However, it is still unknown what role c...

journal_title：Journal of cellular biochemistry

authors： Wang Y,Li SF,Dang YJ,Shi XM,Chen L,Wang N,Cai Y,Zhao YY

更新日期：2020-01-01 00:00:00

abstract：:Arsenic is the first metal to be identified as a human carcinogen. Arsenite, one inorganic form of arsenic, has been found to induce sister chromatid exchange, chromosome aberrations, and gene amplification in a variety of in vitro systems. In this study of arsenite-induced genotoxicity represented a micronuclei produ...

journal_title：Journal of cellular biochemistry

authors： Liu YC,Huang H

更新日期：1997-03-01 00:00:00

abstract：:During inflammation, overproduction of nitric oxide (NO) can damage chondrocytes. In this study, we separately evaluated the toxic effects of exogenous and endogenous NO on human chondrocytes and their possible mechanisms. Human chondrocytes were exposed to sodium nitroprusside (SNP), an NO donor, or a combination of ...

journal_title：Journal of cellular biochemistry

authors： Wu GJ,Chen TG,Chang HC,Chiu WT,Chang CC,Chen RM

更新日期：2007-08-15 00:00:00

abstract：:We have previously demonstrated the direct involvement of a type 1 Ser/Thr phosphatase (PPase 1) in endothelial cell (EC) barrier regulation [Am. J. Physiol. 269:L99-L108, 1995]. To further extend this observation, we microinjected either the Ser/Thr PPase inhibitor, calyculin, or the PPase 1 inhibitory protein, I-2 i...

journal_title：Journal of cellular biochemistry

authors： Verin AD,Csortos C,Durbin SD,Aydanyan A,Wang P,Patterson CE,Garcia JG

更新日期：2000-07-19 00:00:00