Downregulated NOX4 underlies a novel inhibitory role of microRNA-137 in prostate cancer.

abstract：:Toxoplasma gondii excreted-secreted antigens (ESA) could lead to the fetal abortion especially in the early stage of pregnancy. Deficit in regulatory T cells is a critical event in the fetal abortion. Transcription factor forkhead box p3 (Foxp3) mediates differentiation and functional roles on regulatory T cells. Prev...

journal_title：Journal of cellular biochemistry

authors： Chen J,Huang C,Zhu D,Chen L,Wang J,Sun X,Hu L,Duan Y

更新日期：2018-12-01 00:00:00

abstract：:Glutathione S-transferases (GSTs, EC 2.5.1.18) belong to a large family of functionally different enzymes that catalyze the S-conjugation of glutathione with a wide variety of electrophilic compounds including carcinogens and anticancer drugs. Drug resistance may result from reduction in apoptosis of neoplastic cells ...

journal_title：Journal of cellular biochemistry

authors： Bernardini S,Bernassola F,Cortese C,Ballerini S,Melino G,Motti C,Bellincampi L,Iori R,Federici G

更新日期：2000-04-01 00:00:00

abstract：:The effects of serum on inositol 1,4,5-trisphosphate (IP3) formation and Ca2+ mobilization in the human submandibular cell line A253 were studied. Exposure of A253 cells to fetal bovine serum (FBS) elicited a 3.3-fold increase in IP3 formation and a concentration-dependent transient increase in cytosolic free Ca2+ con...

journal_title：Journal of cellular biochemistry

authors： Sun X,Mörk AC,Helmke RJ,Martinez JR,Zhang GH

更新日期：1999-06-15 00:00:00

abstract：:Astrocytes, the major glial population in the central nervous system (CNS), can secrete thrombospondin (TSP)-1 that plays the role in synaptogenesis and axonal sprouting during CNS development and tissue repair. However, little is known about the regulation of TSP-1 expression in astrocytes under oxidative stress cond...

journal_title：Journal of cellular biochemistry

authors： Chen JK,Zhan YJ,Yang CS,Tzeng SF

更新日期：2011-01-01 00:00:00

abstract：:DNA methylation has been studied with regard to chemotherapeutics for a number of years. The radiation field has just begun to look at this in the context of radiotherapy or radiation exposure. So far, the data suggest that radiation induces epigenetic reprogramming which indicates a purposeful response that influence...

journal_title：Journal of cellular biochemistry

authors： Zielske SP

更新日期：2015-02-01 00:00:00

abstract：:Platelets, which play a central role in thrombosis and hemostasis, develop from megakaryocytes. Signal transduction originated from the megakaryocyte growth and development factor, the Mpl ligand, which leads to megakaryocyte differentiation, polyploidization, and maturation, has been gradually characterized. In this ...

journal_title：Journal of cellular biochemistry

authors： Sun S,Ravid K

更新日期：1999-11-01 00:00:00

abstract：:Clear cell renal cell carcinoma (ccRCC) is the main subtype of renal cell carcinoma with varied prognosis. We aimed to identify and assess the possible prognostic long noncoding RNA (lncRNA) biomarkers. LncRNAs expression data and corresponding clinical information of 619 ccRCC patients were downloaded from The Cancer...

journal_title：Journal of cellular biochemistry

authors： Zhang C,Huang D,Liu A,Xu Y,Na R,Xu D

更新日期：2020-03-01 00:00:00

abstract：:Selected clones of Syrian hamster DDT1-MF2 cells are responsive to testosterone for growth. Heparin binding growth factor 1 (HBGF-1) or acidic fibroblast growth factor (aFGF) can replace testosterone (T) in the stimulation of growth in these cells. This phenomena is correlated with testosterone's ability to elevate aF...

journal_title：Journal of cellular biochemistry

authors： Hall JA,Harris MA,Intres R,Harris SE

更新日期：1993-01-01 00:00:00

abstract：:Altered expression of ABH blood group substances is a common feature of human colorectal carcinoma, yet it remains unclear how these structural changes influence the biological properties of tumor cells. Azoxymethane-induced rat colon tumors display many features of the human disease, thereby providing a potentially u...

journal_title：Journal of cellular biochemistry

authors： Laferté S,Prokopishyn NL,Moyana T,Bird RP

更新日期：1995-01-01 00:00:00

abstract：:Cancer of the ovary is the leading cause of death from gynecologic malignancy. To understand better these aggressive tumors, the development of in vitro models to study human ovarian cancer is critical. However, the establishment of long-term cell lines has been difficult, due to the generalized poor survival of patie...

journal_title：Journal of cellular biochemistry

authors： Becker JL,Prewett TL,Spaulding GF,Goodwin TJ

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:MIAT may be implicated in the pathogenesis of age-related hearing loss (AHL). This study aimed to clarify the effect of a MIAT signaling pathway on the risk of AHL. METHODS:Terminal deoxynucleotidyl transferase dUTP nick-end labeling assay, auditory brainstem response (ABR) and quantitative hair cell counts...

journal_title：Journal of cellular biochemistry

authors： Hao S,Wang L,Zhao K,Zhu X,Ye F

更新日期：2019-04-01 00:00:00

abstract：:Insulin receptor was examined as a substrate for the multipotential protein kinase casein kinase I. Casein kinase I phosphorylated partially purified insulin receptor from human placenta as shown by immunoprecipitation of the complex with antiserum to the insulin receptor. Analysis of the phosphorylated complex by pol...

journal_title：Journal of cellular biochemistry

authors： Tuazon PT,Pang DT,Shafer JA,Traugh JA

更新日期：1985-01-01 00:00:00

abstract：:Rearrangement of cell-cell adhesion is a critical event in embryonic development and tissue formation. We investigated the regulatory function of E-cadherin, a key adhesion protein, in the developmental process by using E-cadherin/IgG Fc fusion protein as an adhesion matrix in cell culture. F9 embryonal carcinoma cell...

journal_title：Journal of cellular biochemistry

authors： Nagaoka M,Ise H,Harada I,Koshimizu U,Maruyama A,Akaike T

更新日期：2008-01-01 00:00:00

abstract：:Coriander (Coriandrum sativum L.) is such an herb from the Apiaceae family, used both for its medicinal and nutritional properties for many centuries. In this study, the effects of C. sativum extract on gene expression, viability, colony formation, migration, and invasion of PC-3 and LNCaP prostate cancer cell lines h...

journal_title：Journal of cellular biochemistry

authors： Elmas L,Secme M,Mammadov R,Fahrioglu U,Dodurga Y

更新日期：2019-03-01 00:00:00

abstract：:Increasing evidence have proved that long noncoding RNAs (lncRNAs) play significant roles in tumorigenesis and development of various cancers. However, the effect of small nucleolar RNA host gene 20 (SNHG20) on the progression of esophageal squamous cell carcinoma (ESCC) remains to be discovered. Herein, we aim to fin...

journal_title：Journal of cellular biochemistry

authors： Zhang C,Jiang F,Su C,Xie P,Xu L

更新日期：2019-02-14 00:00:00

abstract：:The regulatory machinery that governs genetic and epigenetic control of gene expression is compartmentalized in nuclear microenvironments. Temporal and spatial parameters of regulatory complex organization and assembly are functionally linked to biological control and are compromised with the onset and progression of ...

journal_title：Journal of cellular biochemistry

authors： Stein GS,Zaidi SK,Stein JL,Lian JB,van Wijnen AJ,Montecino M,Young DW,Javed A,Pratap J,Choi JY,Ali SA,Pande S,Hassan MQ

更新日期：2008-08-15 00:00:00

abstract：:Recently, it has been revealed that estrogen-related reproductive factors are linked with some early gene expression lesions associated with malignancy in clinically healthy breasts. Accordingly, the aim of the current study was to evaluate the association of expression levels of estrogen-related long noncoding RNAs (...

journal_title：Journal of cellular biochemistry

authors： Mansoori Y,Zendehbad Z,Askari A,Kouhpayeh A,Tavakkoly-Bazzaz J,Nariman-Saleh-Fam Z,Bastami M,Saadatian Z,Mansoori B,Yousefvand A,Mansoori H,Daraei A

更新日期：2019-06-01 00:00:00

abstract：:Bone marrow-derived mesenchymal stem cells (MSC), are multipotent cells that give rise to multiple lineages including osteoblasts, adipocytes, muscle, and fibroblasts. MSCs are useful for clinical applications such as cell therapy because they can be isolated from an individual and expanded for use in tissue repair, a...

journal_title：Journal of cellular biochemistry

authors： Cakouros D,Raices RM,Gronthos S,Glackin CA

更新日期：2010-08-15 00:00:00

abstract：:In our previous study, preliminary data indicates that Poria cocos polysaccharides (PCP) shows beneficial hepatoprotection against acetaminophen (APAP)-induced liver injury in mice. However, biological molecular mechanism warrants to be further discussed. In current study, a number of biochemical tests and immunoassay...

journal_title：Journal of cellular biochemistry

authors： Wu K,Guo C,Yang B,Wu X,Wang W

更新日期：2019-05-01 00:00:00

abstract：:Survivin is a member of the inhibitor of apoptosis (IAP) gene family, containing a single baculovirus IAP repeat (BIR) and no RING finger, that is expressed in many human cancers. Although it has been proposed to be involved in mitotic and cytokinetic processes, its functional subcellular distribution in the cytoplasm...

journal_title：Journal of cellular biochemistry

authors： Jiang X,Wilford C,Duensing S,Munger K,Jones G,Jones D

更新日期：2001-08-01 00:00:00

abstract：:Inflammation in vascular (mostly arterial) walls and heart valves triggered by the trans-endothelial influx of LDL particles and the action of subsequently modified (e.g., by oxidation) LDL particles can trigger true bone formation by valvar fibroblasts, by a subpopulation of re-differentiation-competent VSMCs (vascul...

journal_title：Journal of cellular biochemistry

authors： Whitfield JF

更新日期：2005-06-01 00:00:00

abstract：:Primary chicken mesenchymal cells from limb buds and vertebral chondrocytes have been used to study the changes that occur in alternative mRNA splicing of fibronectin exon EIIIA during chondrogenesis. The mesenchymal cell phenotype (exon EIIIA included) and chondrocyte phenotype (exon EIIIA excluded) were preserved in...

journal_title：Journal of cellular biochemistry

authors： Uporova TM,Norton PA,Tuan RS,Bennett VD

更新日期：1999-12-01 00:00:00

abstract：:Our previous study demonstrate that vitamin D3 induces the binding of vitamin D3 receptor (VDR) to Sp1 transcription factor and stimulates p27Kip1 expression via the Sp1 consensus sequences in the promoter. Both VDR and Sp1 are transcriptional activators, it is unclear which protein functions as the transcription comp...

journal_title：Journal of cellular biochemistry

authors： Cheng HT,Chen JY,Huang YC,Chang HC,Hung WC

更新日期：2006-08-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a severe disease with high mortality in the world. It has been shown that long noncoding RNA (lncRNA) might play a role in HCC. The aim of the present study was to identify the role of long intergenic noncoding RNA 01551 (LINC01551) in the HCC development and explore the underlying me...

journal_title：Journal of cellular biochemistry

authors： Gao J,Yin X,Yu X,Dai C,Zhou F

更新日期：2019-10-01 00:00:00

abstract：:Multiple levels of nuclear structure contribute to functional interrelationships with transcriptional control in vivo. The linear organization of gene regulatory sequences is necessary but insufficient to accommodate the requirements for physiological responsiveness to homeostatic, developmental, and tissue-related si...

journal_title：Journal of cellular biochemistry

authors： Stein GS,Stein JL,Lian JB,van Wijnen AJ,Montecino M

更新日期：1996-08-01 00:00:00

abstract：:Transforming growth factor-beta1 (TGF-beta1) action is known to be initiated by its binding to multiple cell surface receptors containing serine/threonine kinase domains that act to stimulate a cascade of signaling events in a variety of cell types. We have previously shown that TGF-beta1 and BMP-2 treatment of primar...

journal_title：Journal of cellular biochemistry

authors： Nesti LJ,Caterson EJ,Li WJ,Chang R,McCann TD,Hoek JB,Tuan RS

更新日期：2007-05-15 00:00:00

abstract：:Rad51-mediated homologous recombination (HR) is essential for maintenance of genome integrity. The Xrcc3 protein functions in HR DNA repair, and studies suggest it has multiple roles at different stages in this pathway. Defects in vertebrate XRCC3 result in elevated levels of spontaneous and DNA damage-induced chromos...

journal_title：Journal of cellular biochemistry

authors： Forget AL,Bennett BT,Knight KL

更新日期：2004-10-15 00:00:00

abstract：:Many regions of the adult central nervous system contain cycling cells. Such cells comprise a relatively small fraction of the total population of the CNS. Work over decades has attempted to determine the normal fates of these cells and their fates under pathological conditions. The recent interest in "stem" cells and...

journal_title：Journal of cellular biochemistry

authors： Goldman JE

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:This study was designed to explore the protective effect of 2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucoside (TSG) against ischemia/reperfusion (I/R) injury-induced cardiomyocytes apoptosis. METHODS:The H9c2 cell I/R injury model was induced by simultaneous shortage of nutrients and oxygen. TSG administration...

journal_title：Journal of cellular biochemistry

authors： Sun T,Liu H,Cheng Y,Yan L,Krittanawong C,Li S,Qian W,Su W,Chen X,Hou X,Zhang H

更新日期：2019-03-19 00:00:00

abstract：:Plasminogen activator inhibitor type-1 (PAI-1) is the major negative regulator of the plasmin-dependent pericellular proteolytic cascade. PAI-1 gene expression is normally growth state regulated but frequently elevated in chronic fibroproliferative and neoplastic diseases affecting both stromal restructuring and cellu...

journal_title：Journal of cellular biochemistry

authors： Qi L,Allen RR,Lu Q,Higgins CE,Garone R,Staiano-Coico L,Higgins PJ

更新日期：2006-10-01 00:00:00