Regulation of Histone Acetylation on Expression Profiles of Potassium Channels During Cardiomyocyte Differentiation From Mouse Embryonic Stem Cells.

abstract：:Activation of cytokine signaling via the leukemia inhibitory factor receptor (LIFR) plays an integral role in hematopoiesis, osteogenesis, and placental development, along with mediating neurotrophic mechanisms. However, the regulatory control of the LIFR gene has remained largely unexplored. Here, we characterize the...

journal_title：Journal of cellular biochemistry

authors： Qadi AA,Taberlay PC,Phillips JL,Young A,West AC,Brettingham-Moore KH,Dickinson JL,Holloway AF

更新日期：2016-01-01 00:00:00

abstract：:Pristimerin is a natural product derived from the Celastraceae and Hippocrateaceae families that were used as folk medicines for anti inflammation in ancient times. Although it has been shown that pristimerin induces apoptosis in breast cancer cells, the involved mechanism of action is unknown. The purpose of the curr...

journal_title：Journal of cellular biochemistry

authors： Yang H,Landis-Piwowar KR,Lu D,Yuan P,Li L,Reddy GP,Yuan X,Dou QP

更新日期：2008-01-01 00:00:00

abstract：:Cervical cancer is one of the leading killers for female worldwide. Nevertheless, the less knowledge of molecular mechanism for cervical cancer limited the improvement of treatment effects. High-mobility group box 2 (HMGB2) belongs to the HMGB family, which could play diverse roles in cell proliferation. This work mai...

journal_title：Journal of cellular biochemistry

authors： Zhang P,Lu Y,Gao S

更新日期：2019-10-01 00:00:00

abstract：:There were 134,000 new diagnosis and 49,000 deaths in 2016 due to colorectal cancer. Similar to most cancers, early diagnosis increases the chance of successful treatment. Detection of tumor-associated antigens or the immune response against such markers is one of the most common methods of diagnosis. In that regard, ...

journal_title：Journal of cellular biochemistry

authors： Veisi Malekshahi Z,Amani J,Negahdari B,Rajabibazl M,Ebrahimizadeh W

更新日期：2018-04-01 00:00:00

abstract：:Cell motility, growth, and proliferation are regulated by adhesion to the extracellular matrix. Detachment of adherent cells from extracellular matrix results in induction of apoptosis ("anoikis"). Transformed cells often show an anchorage-independent growth that enables them to acquire a motile, invasive phenotype. T...

journal_title：Journal of cellular biochemistry

authors： Marco RA,Díaz-Montero CM,Wygant JN,Kleinerman ES,McIntyre BW

更新日期：2003-04-01 00:00:00

abstract：:Regulation and function of PI 3K/Akt and mitogen-activated protein kinases (MAPKs) in doxorubicin-induced cell death were investigated in human lung adenocarcinoma cells. Doxorubicin induced dose-dependent apoptosis of human lung adenocarcinoma NCI-H522 cells. Prior to cell death, both Akt and the MAPK family members ...

journal_title：Journal of cellular biochemistry

authors： Zhao Y,You H,Yang Y,Wei L,Zhang X,Yao L,Fan D,Yu Q

更新日期：2004-02-15 00:00:00

abstract：:Betulinic acid (BA), a pentacyclic triterpene derived from the bark of the white birch tree, has been reported to have a variety of pharmacological effects, including antioxidant, anti-inflammatory, antitumor, immunomodulatory, and antiarthritis properties. However, the role of BA in rheumatoid arthritis (RA) remains ...

journal_title：Journal of cellular biochemistry

authors： Wang J,Zhao Q

更新日期：2018-10-26 00:00:00

abstract：:With a signal trap method, we previously identified stromal interaction molecule (STIM: originally named as SIM) as a protein, which has a signal peptide in 1996. However, recent works have accumulated evidences that STIM1 and STIM2 reside in endoplasmic reticulum (ER) and that both mainly sense ER Ca(2+) depletion, w...

journal_title：Journal of cellular biochemistry

authors： Saitoh N,Oritani K,Saito K,Yokota T,Ichii M,Sudo T,Fujita N,Nakajima K,Okada M,Kanakura Y

更新日期：2011-01-01 00:00:00

abstract：:Protein-tyrosine phosphatases (PTPases) play an important role in the regulation of insulin action by dephosphorylating the active (autophosphorylated) form of the insulin receptor and attenuating its tyrosine kinase activity. PTPases can also modulate post-receptor signalling by catalyzing the dephosphorylation of ce...

journal_title：Journal of cellular biochemistry

authors： Goldstein BJ

更新日期：1992-01-01 00:00:00

abstract：:L-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) are adhesion molecules that play critical roles in neutrophil rolling during inflammation and lymphocyte homing. On the other hand they also function as signaling receptors to induce cytoskeleton changes. The present study is to investigate the signaling kinases...

journal_title：Journal of cellular biochemistry

authors： Luo J,Xu T,Wang X,Ba X,Feng X,Deepak V,Zeng X

更新日期：2010-07-01 00:00:00

abstract：:The function of the c-myc proto-oncogene in cell cycle progression remains unclear. In order to examine the role c-myc may play in cell cycle progression, we have expressed the hormone-inducible MycER protein in the nontransformed, EGF-dependent mouse keratinocyte cell line BALB/MK. We have found that activation of My...

journal_title：Journal of cellular biochemistry

authors： Alexandrow MG,Moses HL

更新日期：1998-09-15 00:00:00

abstract：:Periodontitis, a common chronic inflammatory disease of the periodontium, is caused by dental plaque formation induced by microorganisms. Recent studies have demonstrated that lncRNAs play a critical role in the regulation of gene expression and in the pathogenesis of diseases. To demonstrate that periodontitis is ass...

journal_title：Journal of cellular biochemistry

authors： Zou Y,Li C,Shu F,Tian Z,Xu W,Xu H,Tian H,Shi R,Mao X

更新日期：2015-04-01 00:00:00

abstract：:This study aims to explore the effects of shRNA-mediated silencing on Pyruvate kinase type M2 (PKM2) gene during aerobic glycolysis in colorectal cancer (CRC) cells. CRC tissues and adjacent normal tissues were obtained from 136 patients diagnosed with qRT-PCR, Western blotting, and immunohistochemistry (IHC) were per...

journal_title：Journal of cellular biochemistry

authors： Yan XL,Zhang XB,Ao R,Guan L

更新日期：2017-12-01 00:00:00

abstract：:The epidermal growth factor receptor (EGFR) exhibits an inverse correlation with estrogen receptor (ER) expression in the majority of breast cancers, predicting a poor response to endocrine therapy and poor survival rate. Inappropriate overexpression of EGFR in breast cancer is associated with a more aggressive phenot...

journal_title：Journal of cellular biochemistry

authors： Wilson MA,Chrysogelos SA

更新日期：2002-01-01 00:00:00

abstract：:Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising cancer therapeutic agent because of its tumor selectivity. TRAIL is known to induce apoptosis in cancer cells but spare most normal cells. In the previous study [Yoo and Lee, 2007], we have reported that hyperthermia could enhance the cytot...

journal_title：Journal of cellular biochemistry

authors： Yoo J,Lee YJ

更新日期：2008-01-01 00:00:00

abstract：:Cranial sutures are important growth sites of the skull. During suture closure, the dura mater is one of the most important sources of various positive and negative regulatory signals. Previous results indicate that TGF-beta2 from dura mater strongly accelerates suture closure, however, its exact regulatory mechanism ...

journal_title：Journal of cellular biochemistry

authors： Lee SW,Choi KY,Cho JY,Jung SH,Song KB,Park EK,Choi JY,Shin HI,Kim SY,Woo KM,Baek JH,Nam SH,Kim YJ,Kim HJ,Ryoo HM

更新日期：2006-07-01 00:00:00

abstract：:Extracellular matrix (ECM) accumulation plays a key role in the progression of bladder outlet obstruction (BOO). Muscarinic receptors have been widely reported to serve as pivotal regulators in lung tissue remodeling. However, the influence of them on human bladder smooth muscle cells (HBSMCs) and the underlying molec...

journal_title：Journal of cellular biochemistry

authors： Chen S,Liao B,Jin X,Wei T,He Q,Lin Y,Ai J,Gong L,Li H,Wang K

更新日期：2020-11-01 00:00:00

abstract：:The CRISPR-Cas system is a key technology for genome editing and regulation in a wide range of organisms and cell types. Recently, CRISPR-Cas-based diagnostic platform has shown idealistic properties for pathogen detection. Integrating the CRISPR-Cas platform along with lateral flow system allows rapid, sensitive, spe...

journal_title：Journal of cellular biochemistry

authors： Khambhati K,Bhattacharjee G,Singh V

更新日期：2019-03-01 00:00:00

abstract：:In mice, the first round of DNA replication occurs in fertilized eggs (1-cell embryos), while the onset of zygotic gene transcription begins approximately 20 hours after fertilization, a time that normally coincides with formation of a 2-cell embryo. One approach to investigating the mechanisms that control these deve...

journal_title：Journal of cellular biochemistry

authors： Majumder S,DePamphilis ML

更新日期：1994-05-01 00:00:00

abstract：:The caspase family of protease is speculated to have a crucial role in apoptosis. The effect of treatment with Idarubicin (IDA) and Medroxyprogesterone acetate (MPA), used alone or in combination, on the activation of Caspase-3 in canine Chronic Lymphatic Leukaemia (CLL) cells was investigated, in order to clarify the...

journal_title：Journal of cellular biochemistry

authors： Florio S,Crispino L,Ciarcia R,Vacca G,Pagnini U,de Matteis A,Pacilio C,D'Andrilli G,Kumar C,Giordano A

更新日期：2003-07-01 00:00:00

abstract：:Numerous data indicate that hyperhomocysteinemia is a risk factor for cardio- and cerebrovascular diseases. At least in part, homocysteine (HCY) impairs cerebrovascular function because it generates large numbers of free radicals. Since melatonin is a well-known antioxidant, which reduces oxidative stress and decrease...

journal_title：Journal of cellular biochemistry

authors： Ortega-Gutiérrez S,Fuentes-Broto L,García JJ,López-Vicente M,Martínez-Ballarín E,Miana-Mena FJ,Millán-Plano S,Reiter RJ

更新日期：2007-10-15 00:00:00

abstract：:Craniosynostosis is a condition in which some or all of the sutures in the skull of an infant close prematurely. Fibroblast growth factor receptor 2 (FGFR2) mutations are a well-known cause of craniosynostosis. Many syndromes that comprise craniosynostosis, such as Apert syndrome, Crouzon syndrome, and Pfeiffer syndro...

journal_title：Journal of cellular biochemistry

authors： Park J,Park OJ,Yoon WJ,Kim HJ,Choi KY,Cho TJ,Ryoo HM

更新日期：2012-02-01 00:00:00

abstract：:The promoter of the mouse thymidylate synthase (TS) gene lacks a TATAA box and an initiator element, is bidirectional and initiates transcription at multiple start sites across broad initiation windows upstream and downstream of the 30 nt essential promoter region. The TS promoter also plays an essential role in the p...

journal_title：Journal of cellular biochemistry

authors： Kapadia F,Johnson LF

更新日期：2006-02-15 00:00:00

abstract：:Bone is a target tissue of progestins, but the mechanisms by which they act are still unclear. We examined the early (5-60 s) effects of progesterone and progesterone covalently bound to BSA (P-CMO BSA), which does not enter the cell, on the cytosolic free Ca(2+) concentration ([Ca(2+)]i) and the formation of inositol...

journal_title：Journal of cellular biochemistry

authors： Grosse B,Kachkache M,Le Mellay V,Lieberherr M

更新日期：2000-08-02 00:00:00

abstract：:Follicle-stimulating hormone-follicle-stimulating hormone receptor (FSH-FSHR) interaction is one of the most thoroughly studied signaling pathways primarily because of being implicated in sexual reproduction in mammals by way of maintaining gonadal function and sexual fertility. Despite material advances in understand...

journal_title：Journal of cellular biochemistry

authors： Gharemirshamlu FR,Afsar M,Mokhdomi TA,Amin A,Bukhari S,Krishnan A,Kumar CV,Bamdad K,Patel TN,Qadri RA,Chikan NA,Shabir N

更新日期：2018-11-02 00:00:00

abstract：:In this study, we have used the tumor promoter 12-o-tetradecanoylphorbol-13-acetate (TPA), as well as its biologically inactive analogue 4 alpha-phorbol 12,13-didecanoate (4 alpha-PDD), to investigate platelet protein phosphorylation and its possible correlation with platelet activation. Our data show that TPA, but no...

journal_title：Journal of cellular biochemistry

authors： Bourguignon LY,Field S,Bourguignon GJ

更新日期：1985-01-01 00:00:00

abstract：:The mammalian target of rapamycin (mTOR) pathway is dysregulated in more than 50% of all human malignancies and is a major target in cancer treatment. In this study, we explored the underlying mechanism involving microRNA-145-3p (miR-145-3p) in the development and progression of non-small cell lung cancer (NSCLC) by t...

journal_title：Journal of cellular biochemistry

authors： Chen GM,Zheng AJ,Cai J,Han P,Ji HB,Wang LL

更新日期：2018-01-01 00:00:00

abstract：:Recently, it has been revealed that estrogen-related reproductive factors are linked with some early gene expression lesions associated with malignancy in clinically healthy breasts. Accordingly, the aim of the current study was to evaluate the association of expression levels of estrogen-related long noncoding RNAs (...

journal_title：Journal of cellular biochemistry

authors： Mansoori Y,Zendehbad Z,Askari A,Kouhpayeh A,Tavakkoly-Bazzaz J,Nariman-Saleh-Fam Z,Bastami M,Saadatian Z,Mansoori B,Yousefvand A,Mansoori H,Daraei A

更新日期：2019-06-01 00:00:00

abstract：:Rearrangement of cell-cell adhesion is a critical event in embryonic development and tissue formation. We investigated the regulatory function of E-cadherin, a key adhesion protein, in the developmental process by using E-cadherin/IgG Fc fusion protein as an adhesion matrix in cell culture. F9 embryonal carcinoma cell...

journal_title：Journal of cellular biochemistry

authors： Nagaoka M,Ise H,Harada I,Koshimizu U,Maruyama A,Akaike T

更新日期：2008-01-01 00:00:00

abstract：:DNA methylation plays a role in the etiology of primary breast cancers. We analyzed paired primary and second breast tumors to elucidate the role of methylation in recurrence. Methylation profiles from paired primary and second breast tumors of 23 women were assessed using the HumanMethylation450 BeadChip. Twelve wome...

journal_title：Journal of cellular biochemistry

authors： Williams KE,Jawale RM,Schneider SS,Otis CN,Pentecost BT,Arcaro KF

更新日期：2019-01-01 00:00:00