Seroprevalence of Human Brucellosis in Wadi Al Dawaser region of Saudi Arabia.

Abstract:

Background and Objective:Brucellosis is an important zoonotic disease and a major public health problem in the Middle East countries including Saudi Arabia. This study has evaluated the seroprevalence of human brucellosis in Wadi Al Dawaser region of Central Saudi Arabia. Methods:The study was conducted for three years (2015-2018) at Wadi Al Dawaser general hospital. A total of 6721 clinically suspected serum samples were collected over three years and tested by Rose Bengal Plate Test (RBPT), Serum Agglutination Test (SAT), IgM and IgG ELISA. A standard questionnaire to determine the risk factors were used among patients. Results:Of the total 6721 samples tested, 576 (8.6%) were seropositive for brucellosis. RBPT identified 427 (74.1%), SAT titers 493 (85.6%) cases. IgM ELISA and IgG ELISA were positive for 501 (86.9%) and 558 (96.8%) cases respectively. Among the positive cases, 77.3% were male with the male to female ratio of 3.3:1. Nearly, 82% were Saudi Nationals. Direct contact with domestic animals and consumption of raw milk were the risk factors identified. No seasonal variation was seen. Diagnostic yield of IgM ELISA showed 86.9% sensitivity and 100% specificity; IgG ELISA showed 96.8% sensitivity and 100% specificity. Both IgG and IgM ELISAs showed 100% Positive predictive value, 98.9% and 95.6% Negative predictive value respectively. Conclusion:A seroprevalence of 8.6% of human brucellosis was documented from this rural region. This is the first report from Wadi Al Dawaser. Frequent surveillance among risk group, vaccination of livestock, creating awareness and health education among the public and school children are recommended.

journal_name

Pak J Med Sci

authors

Rahamathulla MP

doi

10.12669/pjms.35.1.55

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

129-135

issue

1

eissn

1682-024X

issn

1681-715X

pii

PJMS-35-129

journal_volume

35

pub_type

杂志文章
  • Frequency of migraine in patients with allergic rhinitis.

    abstract:OBJECTIVES:Allergic rhinitis (AR) is an IgE mediated disease which is released by activation of mast cells and basophils, and often leads to sinus headache. Histamine which is the key mediator in the pathogenesis of AR, also plays an important role in the pathogenesis of migraine with nitric oxide (NO). Aim of our stud...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.292.3148

    authors: Ozturk A,Degirmenci Y,Tokmak B,Tokmak A

    更新日期:2013-04-01 00:00:00

  • Self-perceived oral symptoms and periodontal inflammatory conditions in habitual naswar dippers.

    abstract:Objectives:To compare self-perceived oral symptoms and clinical (plaque index [PI], bleeding on probing [BOP], clinical attachment loss [CAL]) and radiographic (marginal bone loss [MBL]) periodontal parameters among naswar (NW) and non-naswar dippers (NNW). Methods:One hundred and forty-two individuals (72 patients co...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.345.15418

    authors: Al-Hamoudi N,Mokeem S,Jabbar TA,FahimVohra,Akram Z

    更新日期:2018-09-01 00:00:00

  • Allergic Fungal rhino-sinusitis frequency in chronic rhino-sinusitis patients and accuracy of fungal culture in its diagnosis.

    abstract:Objective:To determine the frequency of Allergic Fungal Rhino-sinusitis (AFRS) in Chronic Rhino-sinusitis (CRS) patients and the accuracy of fungal culture in diagnosing AFRS. Methods:Immunocompetent patients with CRS and without invasive fungal rhino-sinusitis presenting over a period of 3 years in ENT department of ...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.36.3.1661

    authors: Awan NU,Cheema KM,Naumeri F,Qamar S

    更新日期:2020-03-01 00:00:00

  • The interface of psychiatry and COVID-19: Challenges for management of psychiatric patients.

    abstract::COVID-19 is a viral infection that has multisystemic physical and psychological complications. The following paper looks at the various challenges seen while treating psychiatric patients during the COVID pandemic. There is a need for physician to be aware of the drug interactions between psychiatric medications and t...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.36.5.3073

    authors: Javed A,Mohandas E,Sousa A

    更新日期:2020-07-01 00:00:00

  • Trans fatty acids - A risk factor for cardiovascular disease.

    abstract::Trans fatty acids (TFA) are produced either by hydrogenation of unsaturated oils or by biohydrogenation in the stomach of ruminant animals. Vanaspati ghee and margarine have high contents of TFA. A number of studies have shown an association of TFA consumption and increased risk of cardiovascular disease (CVD). This i...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章,评审

    doi:10.12669/pjms.301.4525

    authors: Iqbal MP

    更新日期:2014-01-01 00:00:00

  • Bisphosphonates can prevent recurrent hip fracture and reduce the mortality in osteoporotic patient with hip fracture: A meta-analysis.

    abstract:OBJECTIVE:This meta-analysis was conducted to investigate the efficacy of bisphosphonates for preventing recurrent hip fracture and reducing the mortality of elderly patient with hip fracture. METHODS:The databases of Pubmed, Embase and Cochrane Library were searched. All randomized or prospective matched controlled t...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章,评审

    doi:10.12669/pjms.322.9435

    authors: Peng J,Liu Y,Chen L,Peng K,Xu Z,Zhang D,Xiang Z

    更新日期:2016-03-01 00:00:00

  • The incidence of preeclampsia in ICSI pregnancies.

    abstract:OBJECTIVE:We aimed to evaluate the association between infertility etiology in ICSI pregnancies and preeclampsia; besides, we aimed to discuss the effect of the paternal factor in the pathogenesis of preeclampsia. HYPOTHESIS:We hypothesized that preeclampsia is more common in ICSI pregnancies with male factor. It is k...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.301.3982

    authors: Ulkumen B,Silfeler D,Sofuoglu K,Silfeler I,Dayicioglu V

    更新日期:2014-01-01 00:00:00

  • Study on risk factors (predisposing factors) for poor diabetes control during Hajj (1436/2015) in people with diabetes.

    abstract:BACKGROUND AND OBJECTIVE:Each year millions of Muslims perform pilgrimage to Makkah, Saudi Arabia. It is particularly stressful during the peak five days, when all rituals have to be performed at specific periods of time at different sites. Poor diabetes control in people with diabetes predisposes to morbidity and incr...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.325.11217

    authors: Hasan G,Moabber H,Alyamani A,Sayeed A,Altatar F

    更新日期:2016-09-01 00:00:00

  • Pheniramine Maleate is more effective than Lidocaine on Fentanyl Induced Cough.

    abstract:OBJECTIVE:Fentanyl is frequently used during anesthesia induction. The use of fentanyl can cause cough through different mechanisms. Here, we aimed to investigate effects of pheniramine maleate (PM), an antihistaminic agent, and compare it with lidocaine on fentanyl induced cough. METHODS:This is a randomized double-b...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.323.9496

    authors: Ozmen O,Kara D,Karaman EU,Karakoc F,Karakaya MA,Arslan Z

    更新日期:2016-05-01 00:00:00

  • Reference range variation in haematological indices amongst five different age groups of less than one year in Islamabad, Pakistan.

    abstract:OBJECTIVE:The objective of the current study was to establish the reference ranges of haematological indices amongst five healthy infantile (<1 year) age groups. METHODOLOGY:It was a descriptive cross sectional study carried out at the Department of Haematology, Armed Forces Institute of Pathology (AFIP), Rawalpindi. ...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.292.3067

    authors: Tauseef Bukhari K,Zafar H

    更新日期:2013-04-01 00:00:00

  • Clinical exploration of marking targeting biopsy in the intraoperative localization value of colon polypectomy.

    abstract:Objective:To evaluate the feasibility and safety of marking targeting biopsy (MTB) in the intraoperative localization value of colon polypectomy. Methods:The clinical data from patients with polyp of colon discovered under colonoscopy from January 2014 to January 2016 were retrospectively analyzed. A total of 87 patie...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.36.2.756

    authors: Song LY,Lin Q,Li LB,Cheng X

    更新日期:2020-01-01 00:00:00

  • Sigmoid volvulus: Comorbidity with sigmoid gangrene.

    abstract::Sigmoid volvulus (SV) is the wrapping of the sigmoid colon around its mesentery, and sigmoid gangrene is a catastrophic complication of SV. Although the diagnosis of SV is generally not difficult, unfortunately, most of the clinical, laboratory and radiological signs are not pathognomonic in demonstrating sigmoid gang...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.35.1.295

    authors: Atamanalp SS,Disci E,Atamanalp RS

    更新日期:2019-01-01 00:00:00

  • KCNQ1 rs2237895 polymorphism is associated with Gestational Diabetes in Pakistani Women.

    abstract:BACKGROUND AND OBJECTIVE:Genetic studies on gestational diabetes (GDM) are relatively scarce; moreover, limited data is available for KCNQ1 polymorphism in Pakistani pregnant women. We aimed to determine the frequency of KCNQ1 rs2237895 in GDM and normal pregnant controls and its association with GDM-related phenotypes...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.326.11052

    authors: Fatima SS,Chaudhry B,Khan TA,Farooq S

    更新日期:2016-11-01 00:00:00

  • Perceived social support in pregnant adolescents in Mersin area in Turkey.

    abstract:Objective:The study examines the level and source of perceived social support in pregnant adolescents and the factors related to their perception of social support. Methods:This descriptive study was conducted with the voluntary participation of 127 adolescent pregnant females who visited the Gynecology and Pediatric ...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.341.14221

    authors: Yurdakul M

    更新日期:2018-01-01 00:00:00

  • Tea drinking habits and osteoporotic hip/femur fractures: A case-control study.

    abstract:OBJECTIVE:To explore the relationship between tea drinking habits and osteoporotic hip/femur fractures. METHODS:Paired case-control method was used for face-to-face interviews from January 2010 to June 2014. Patients (n=435) with newly osteoporotic hip/femur fracture and 435 controls with the same gender and age (±3) ...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.322.9092

    authors: Huang C,Tang R

    更新日期:2016-03-01 00:00:00

  • Association of the use of bacterial cell wall synthesis Inhibitor drugs in early childhood with the Developmental Defects of Enamel.

    abstract:OBJECTIVE:Our objective of the study was to determine the association between frequent use of Penicillins and Cephalosporins with developmental defects of enamel in pediatric age group. METHODS:This is a cross sectional study, conducted at Ziauddin University. A total of 367 children, having the history of either Peni...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:

    authors: Tariq A,Alam Ansari M,Owais Ismail M,Memon Z

    更新日期:2014-03-01 00:00:00

  • Frequency of Vitamin D deficiency in pregnant diabetics at Baskent University Hospital, Istanbul.

    abstract:OBJECTIVE:To find out the frequency of vitamin D deficiency and its relation with glucose parameters and the incidence of gestational diabetes (GDM). METHODOLOGY:Gestational diabetes was diagnosed with 75 gram oral glucose tolerance test. Forty-four pregnant women diagnosed with GDM and 78 non-GDM pregnant women were ...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.291.2896

    authors: Parildar H,Dogruk Unal A,Aksan Desteli G,Cigerli O,Guvener Demirag N

    更新日期:2013-01-01 00:00:00

  • The Relation of Dependency and the Predictive Potential of Several Factors Possibly Involved in Determining Pulmonary Hypertension in Graves' Disease.

    abstract:Objectives:To establish a possible relation of dependency between pulmonary hypertension (PHT) and several factors, with the evaluation of their predictive potential, in Graves' disease. Methods:For identifying the factors implied in producing PHT and for evaluating its reversibility, we made echocardiography exams, s...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.343.14500

    authors: Scarneciu CC,Sangeorzan L,Popescu M,Scarneciu VD,Scarneciu I

    更新日期:2018-05-01 00:00:00

  • A comparison of the scorings of real and standardized patients on physician communication skills.

    abstract:OBJECTIVES:To compare the scorings of real and standardized patients on physician communication skills. METHODS:Patient scoring (n=183) on physicians' communication skills was determined by 93 real and 90 standardized patients. Eighty physicians (42 specialists and 38 general physicians) in private practice were enrol...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.303.3255

    authors: Rezaei R,Mehrabani G

    更新日期:2014-05-01 00:00:00

  • Analysis of the relationship between liver regeneration rate and blood levels.

    abstract:OBJECTIVES:The aim of this study was to investigate the difference of liver function changes according to the liver regeneration rate after liver transplantation through blood tests. METHODS:Fifty donors, who underwent computed tomography (CT) 3D volumetry, were analyzed before and after liver transplantation. CT 3D v...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.311.5864

    authors: Kim MS,Lee HK,Kim SY,Cho JH

    更新日期:2015-01-01 00:00:00

  • Analysis of deep venous thrombosis after Gynecological surgery: A clinical study of 498 cases.

    abstract:OBJECTIVES:To find out the clinical characteristics and risk factors for deep venous thrombosis (DVT) after gynecological surgery. METHODS:Four hundred and ninety-eight patients treated surgically in the department of gynecology of our hospital from July 2012 to May 2014 were reviewed retrospectively. The data includi...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.312.6608

    authors: Zhang L,Liu X,Xue Y

    更新日期:2015-03-01 00:00:00

  • Study on correlation between property of coronary artery lesion and degree of coronary artery stenosis of elderly patients with coronary heart disease.

    abstract:Objective:To discuss the influence of coronary artery lesion of elderly patients with coronary heart disease (CHD) on left ventricular remodeling. Methods:Retrospective selection method was used to choose 80 elderly CHD patients who received coronary angiogram examination in Baoding First Central Hospital from January...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.35.1.225

    authors: Wang C,Tian X,Xia W,Liu Q

    更新日期:2019-01-01 00:00:00

  • Analysis of uterine rupture at university teaching hospital Pakistan.

    abstract:OBJECTIVE:To determine the risk factors, management modalities, fetomaternal outcome of uterine rupture cases at University teaching hospital in Pakistan. METHODS:This retrospective descriptive study was conducted at the Department of Gynaecology and Obstetrics Liaquat University of Medical and Health Sciences (LUMHS)...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.314.7303

    authors: Aziz N,Yousfani S

    更新日期:2015-07-01 00:00:00

  • A Study on Catalase Gene Promoter Polymorphism -21 A/T (rs7943316) in Healthy Pakistani population.

    abstract:Background & Objective:Catalase (CAT) is an important endogenous antioxidant enzyme that detoxifies H2O2 into water and oxygen, consequently limiting the deleterious effects of reactive oxygen species. It has suggested that CAT-21A/T (rs7943316) OMIM: 115500 gene promoter polymorphism is predominantly associated with d...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.336.13188

    authors: Nawab SN,Zehra S,Fawwad A,Azhar A

    更新日期:2017-11-01 00:00:00

  • Role of Mitogen-Activated Protein Kinases in the Formation of Hypertrophic Scar with Model of Lipopolysaccharide Stimulated Skin Fibroblast Cells.

    abstract:Objective:Hypertrophic scar is common in burn patients, but treating result could not meet the expectation of the patients and doctors. We have found that certain concentration level of lipopolysaccharide (LPS) stimulated normal fibroblast cells have statistically similar with fibroblast cells from hypertrophic scar on...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.341.13636

    authors: Wang W,Li G,Yang H

    更新日期:2018-01-01 00:00:00

  • Management options for interstitial ectopic pregnancies: A case series.

    abstract:OBJECTIVE:Ectopic pregnancy in the interstitial part of the Fallopian tubes can be life-threatining considering the thin myometrial tissue surrounding the gestational sac and highly vascularization which may result in catastrophic haemorrhage when interstitium is ruptured. The diagnosis and management is challenging. C...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.332.12093

    authors: Kahramanoglu I,Mammadov Z,Turan H,Urer A,Tuten A

    更新日期:2017-03-01 00:00:00

  • Prevalence and associated risk factors for syphilis in women with recurrent miscarriages.

    abstract:OBJECTIVE:A Cross Sectional population based serological studies was conducted to determine the prevalence and associated risk factors for syphilis women with recurrent miscarriages. METHODS:Patient's 5ml whole blood was collected through venepuncture technique. Data were collected by all women answered a questionnair...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:

    authors: Hussain Laghari A,Sultana V,Hussain Samoo A,Makhija P,Ara J,Hira

    更新日期:2014-03-01 00:00:00

  • Culture and PCR based detection of bacteria causing urinary tract infection in urine specimen.

    abstract:Objectives:Urinary tract infections are the second most common bacterial infections occurring at all ages and both sexes. The increasing rate of antibiotic resistance is a global concern. The use of routinely used antibiotics is resulting in treatment failure. The objective of this study was to diagnose the urinary tra...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.36.3.1577

    authors: Pirkani GS,Awan MA,Abbas F,Din M

    更新日期:2020-03-01 00:00:00

  • Relationship between myocardial enzyme levels, hepatic function and metabolic acidosis in children with rotavirus infection diarrhea.

    abstract:Objective:To investigate the relationship between myocardial enzymes, liver function and metabolic acidosis in children with rotavirus infection diarrhea. Methods:The data of 70 children with infectious diarrhea treated in Baoding Children's Hospital, China, from October 2017 to April 2018 were retrospectively studied...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.36.6.2325

    authors: Zuo NY,Zhang YD,Dong QW,Han LP

    更新日期:2020-09-01 00:00:00

  • Correlation between uterine fibroids with various magnetic resonance imaging features and therapeutic effects of high-intensity focused ultrasound ablation.

    abstract:OBJECTIVE:To explore the correlation between magnetic resonance imaging (MRI) features of uterine fibroids (UFs) and therapeutic effects of high-intensity focused ultrasound ablation (HIFUA), and to provide evidence for UFs diagnosis with MRI in clinical practice. METHODS:Forty-three UFs patients who were treated in o...

    journal_title:Pakistan journal of medical sciences

    pub_type: 杂志文章

    doi:10.12669/pjms.314.7294

    authors: Cheng H,Wang C,Tian J

    更新日期:2015-07-01 00:00:00