Сomorbidity and polymorbidity of the patient with chronic obstructive pulmonary disease and cardiovascular diseases.

Abstract:

AIM:the study of comorbid status and characteristics of clinical course of ischemic heart disease (IHD) in patients with chronic obstructive pulmonary disease (COPD). MATERIALS AND METHODS:We conducted a retrospective analysis of case histories of 958 IHD patients aged 32 to 93 years (mean age of 60.8±10.2 years), including men - 525 (54.8%), women - 433 (45.2%) who were treated in the cardiology Department of city clinical hospital №5 of Nizhny Novgorod. Related COPD was diagnosed in 251 patients (26.3%). We compared two groups patients: with IHD and COPD, and the second - persons suffering from only IHD (without COPD). RESULTS:Myocardial infarction was transferred by 62.2% of patients in Group 1, which is 16.3% more than in Group 2 (p<0.05). Arterial hypertension in patients with COPD was 13.6% more frequent than in patients without COPD (p<0.05), and 6.4% more often (p<0.05), with comorbid pathology there was a chronic and paroxysmal forms of atrial fibrillation. In patients with IHD in combination with COPD it is 21.5% more often (p<0.05) than in IHD without COPD, there was shortness of breath and 32.1% more often (p<0.05) of the heartbeat. In patients with IHD with COPD, a higher level of was C-reactive protein detected (p<0.05) and more pronounced violations of the lipid profile (p<0.05). CONCLUSION:COPD makes a significant contribution to the development of the cardiovascular continuum, modifying its course. A modern patient with COPD is a high-risk patient with severe cardiovascular comorbidity and various polymorbidity.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Grigoryeva NY,Maiorova МV,Korolyova ME,Samolyuk MO

doi

10.26442/00403660.2019.01.000027

subject

Has Abstract

pub_date

2019-03-10 00:00:00

pages

44-47

issue

1

eissn

0040-3660

issn

2309-5342

journal_volume

91

pub_type

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