Abstract:
AIM:the study of comorbid status and characteristics of clinical course of ischemic heart disease (IHD) in patients with chronic obstructive pulmonary disease (COPD). MATERIALS AND METHODS:We conducted a retrospective analysis of case histories of 958 IHD patients aged 32 to 93 years (mean age of 60.8±10.2 years), including men - 525 (54.8%), women - 433 (45.2%) who were treated in the cardiology Department of city clinical hospital №5 of Nizhny Novgorod. Related COPD was diagnosed in 251 patients (26.3%). We compared two groups patients: with IHD and COPD, and the second - persons suffering from only IHD (without COPD). RESULTS:Myocardial infarction was transferred by 62.2% of patients in Group 1, which is 16.3% more than in Group 2 (p<0.05). Arterial hypertension in patients with COPD was 13.6% more frequent than in patients without COPD (p<0.05), and 6.4% more often (p<0.05), with comorbid pathology there was a chronic and paroxysmal forms of atrial fibrillation. In patients with IHD in combination with COPD it is 21.5% more often (p<0.05) than in IHD without COPD, there was shortness of breath and 32.1% more often (p<0.05) of the heartbeat. In patients with IHD with COPD, a higher level of was C-reactive protein detected (p<0.05) and more pronounced violations of the lipid profile (p<0.05). CONCLUSION:COPD makes a significant contribution to the development of the cardiovascular continuum, modifying its course. A modern patient with COPD is a high-risk patient with severe cardiovascular comorbidity and various polymorbidity.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Grigoryeva NY,Maiorova МV,Korolyova ME,Samolyuk MOdoi
10.26442/00403660.2019.01.000027subject
Has Abstractpub_date
2019-03-10 00:00:00pages
44-47issue
1eissn
0040-3660issn
2309-5342journal_volume
91pub_type
杂志文章abstract::Overall 30 patients with multiple myeloma (MM) were examined for immunological and rheological parameters. MM was shown to be marked by imbalance of immunobiological reactivity, with the greatest changes being seen in the B cell immunity system. MM is also characterized by marked rheological shifts related to the immu...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:AIM:to assess the long-term angiographic and clinical results of percutaneous coronary interventions (PCI) with implantation of the drug-eluting stent (DES) Apollo in patients with stable angina pectoris. SUBJECTS AND METHODS:The study enrolled 48 patients with stable angina who had been implanted with 59 stents. A fo...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::The paper concerns the problem of secondary immunodeficiency (SID) in chronic bronchitis (CB) patients. Clinical and laboratory criteria of SID are suggested with clinical illustrations covering 57 cases. SID was diagnosed in 80.7% of the examinees and was associated with reduced quantitative and functional parameters...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::A study was made of the nature of secondary immuno-deficiency, peculiarities of disordered function of regulatory T-lymphocytes (helpers and suppressors), and their interrelationships in different clinical variants of chronic glomerulonephritis (CGN). Altogether 94 CGN patients were examined, of them 34 were with urin...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract:AIM:To examine changes in the structure of large (carotid and femoral) arteries at an early stage of chronic renal failure (CRF) and factors significant for their development. MATERIAL AND METHODS:Duplex ultrasonography of the common carotid arteries (CCA) and common femoral arteries (CFA), serum biochemical tests, ec...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::47 hemofiltration procedures were performed in 10 patients. A self-made balancer based on the volumic hydrodynamics dependent on substitute from filtrate was used. An APD-02 peritoneal dialysis machine served the source of the substitute. It provided change of the concentration and was used for prophylaxis of osmodist...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract:AIM:The primary objective of this study was to describe clinical, virusological and immunological characteristics of hospitalised HIV--infected patients, who had different stages of the disease. MATERIALS AND METHODS:This study was conducted at Moscow Infectious Diseases Hospital №2 in 2012-2015. We have clinically ob...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.26442/terarkh2018901118-23
更新日期:2018-11-21 00:00:00
abstract:AIM:A comparative study of efficiency and safety of low-dose erythropoietin (EP) in two groups of patients with chronic renal failure (CRF): patients on chronic hemodialysis (CHD) and patients on continuous ambulatory hemodialysis (CAHD). MATERIALS AND METHODS:51 CRF adult patients with renal anemia on hemodialysis en...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract:AIM:To assess the presence of insulin resistance (IR) in non-diabetic patients with early forms of non-alcoholic fatty liver disease (NAFLD) - liver steatosis (LS) and steatohepatitis (SH) of mild activity and the influence of IR on the clinical course of these diseases. MATERIALS AND METHODS:134 patients with NAFLD w...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.26442/terarkh201890863-68
更新日期:2018-08-27 00:00:00
abstract::The data on natural course of chronic viral hepatitis C infection (HCV) and the efficacy of antiviral treatment depending on virus genotype are summarized in the article. The significance of virus genotype in progression of liver fibrosis and liver steatosis is discussed. It is pointed out that chronic HCV infection c...
journal_title:Terapevticheskii arkhiv
pub_type: 社论
doi:
更新日期:2012-01-01 00:00:00
abstract:AIM:The retrospective analysis of prevalence, peculiarities of duration of biliary calculosis without gall bladder cholesterosis, biliary calculosis with gall-bladder cholesterosis and xanthogranulematous cholecystitis among persons who underwent cholecystectomy using clinical, instrumental and morphological data. MATE...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::Comparative studies on changes of hemodynamics in manual and leg isometric loads were conducted in 30 healthy persons and 38 patients with coronary heart disease. A possibility of a leg isometric load with a maximum effort for 5 min. was shown. Intracardiac hemodynamics was estimated by echocardiography results. A pos...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::As many as 56 healthy women and 45 women of reproductive age, suffering from essential hypertension (EH) were examined for the effect of ovarian cycle phases on vegetative regulation of central hemodynamics and pharmacodynamic effects of hemiton. The healthy persons in the phase of proliferation (I) and secretion (III...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Among the many causes of the inflammatory process in the esophagus, infectious diseases are becoming increasingly important due to their steady growth. Previously esophageal infections have traditionally been associated with immunodeficiency syndromes, but now in clinical practice, these disorders are becoming increas...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.26442/00403660.2020.08.000763
更新日期:2020-09-03 00:00:00
abstract::The authors relate the results of a clinico-morpho-instrumental analysis of the clinical course of lymphosarcomas in 38 patients with different morphological patterns of the disease with primary injury to the spleen. The patients received multimodality therapy including splenectomy. It has been established that later ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:AIM:To evaluate the efficacy of the enterokinetic prucalopride (resolor) in patients with chronic constipation. SUBJECTS:The effect of treatment with prucalopride (resolor) in 109 patients with chronic constipation was analyzed. RESULTS:The effect was noted in 82% of the patients; 61 patients were fully satisfied wit...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract:AIM:To study effects of methotrexate on the titer of antibodies to mutated citrullinated vimentin (anti-MCV) and ascertain possibility of using this marker for control of treatment results and choice of individual effective dose of the drug. MATERIAL AND METHODS:A 12-month trial included 76 patients with verified rheu...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::A total of 206 patients with acute myocardial infarction marked by infarction localization in the anterior and inferior walls were examined. It is revealed that reciprocal changes, namely the depression of the ST segment are of prognostic significance in the assessment of the clinical course of the disease, with the S...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Available indirect methods were employed to examine 52 patients with a history of myocardial infarction and 18 normal subjects by the end of the early rehabilitation period. Hemodynamic overload of the left atrium was revealed. The main hemodynamic parameters and processes marking contractile and electrical myocardial...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:AIM:To prove the value of summary data from the State Statistics Commission to characterize of risk of death from circulatory system diseases (CSD). MATERIAL AND METHODS:The official data of the State Statistics Commission of the Azerbaijan Republic, which are available at its website (www.stat.gov.az), were analyzed ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.17116/terarkh201688352-55
更新日期:2016-01-01 00:00:00
abstract:AIM:To investigate the impact of menopausal hormone therapy (MHT) on the expression of risk factors for cardiovascular events (CVEs) in patients with Shereshevsky-Turner syndrome (STS); to elaborate an algorithm for patient management using MHT. SUBJECTS AND METHODS:From 2010 to 2012, a total of 41 patients aged 14 to...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.17116/terarkh2017891048-53
更新日期:2017-01-01 00:00:00
abstract::In addition to conventional outpatient treatment 165 psoriasis patients underwent hemosorption (100 cases) or plasmapheresis (65 cases). The efferent methods used proved beneficial in 99 (60%) of the patients that got to have normal hemograms, reduced CIC and middle molecular weight peptides levels in blood. The respo...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:AIM:To study the results of mobilizing and collecting autologous hematopoietic stem cells (HSC) in patients with multiple myeloma (MM) receiving bortezomib as part of induction therapy regimens. MATERIALS AND METHODS:In June 2001 to April 2010, the Department of Bone Marrow Transplantation, Hematology Research Center,...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract::The results of hemodialysis therapy given in 1988-1994 to 57 patients with acute renal failure at the age of 17-62 years in hemorrhagic fever with renal syndrome (HFRS) are provided. A total of 306 procedures were performed. Hemodialysis was initiated early, before clinical presentation of uremia. The indications for ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:AIM:The aim of the study was to study the effectiveness of the complex use of bacterial therapeutic vaccine Immunovac-VP4 and allergen-specific immune therapy (ASIT) in pollinosis in children and adults. MATERIALS AND METHODS:Bacterial therapeutic vaccine Immunovac-VP4 was used annually, nasal and oral administration ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.26442/terarkh201890316-20
更新日期:2018-04-19 00:00:00
abstract:AIM:to characterize the markers of endothelial dysfunction and the effect of antihypertensive drugs on them in patients with chronic urate tubulointestinal nephritis (UTIN) and articular gout. SUBJECTS AND METHODS:The study enrolled 81 patients aged 39 to 59 years with gout and urate nephropathy. All the patients were...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::As many as 24 patients suffering from essential hypertension (EH) were examined. The patients were subjected to Holter ECG monitoring, echocardiography, coronary angiography, exercise scintigraphy of the myocardium with transesophageal pacing of the atria and the dipyridamole test. The patients manifested defects of t...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:AIM:to analyze well-known risk factors (RFs), such as age, immunophenotype, baseline leukocytosis, enhanced lactate dehydrogenase (LDH) activity, time to achieve complete remission, a risk group, and cytogenetic abnormalities) in patients with acute lymphoblastic leukemia (ALL) in the use of the ALL-2009 protocol. SUB...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.17116/terarkh201688715-24
更新日期:2016-01-01 00:00:00
abstract::Antiarrhythmic efficiency and specific effects of ethmozine, taken alone in increasing oral doses from 300 to 450 mg daily, were evaluated in 48 elderly and old coronary patients with stable supraventricular and ventricular extrasystoles (SVES, VES). It was demonstrated clinically and instrumentally (ECG, rhythmograph...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::Altogether 84 patients with duodenal ulcer were examined for a study of mesenchyma function. The blood level of oxyproline, the system of histamine-histaminase-histaminopexic index, and the level of serotonin before and after treatment were studied. The level of IgG, A, M and the amount of T- and B-lymphocytes were de...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00