Abstract:
BACKGROUND:Primary salivary gland-type tumors of the tracheobronchial tree are rare; their cytologic features have been seldom reported. We aim to describe the clinical and cytomorphologic features of tracheobronchial salivary gland-type tumors diagnosed by transbronchial fine needle aspiration (TBNA) at our institution, and correlate the findings with a corresponding surgical specimen. METHODS:We searched our laboratory information system to identify patients with a primary salivary gland-type neoplasm of the tracheobronchial tree diagnosed by TBNA and with a corresponding surgical pathology specimen, over 10 years. RESULTS:The study cohort consisted of 11 patients (7F/4M; mean age 58 years, range 41-78). Presenting symptoms included hemoptysis (4), cough (3), dyspnea (1), stridor (1), and shoulder pain (1). Most had a tracheal mass (5), while 3 had mainstem bronchi masses and 3 had lung masses. Radiographically, the masses were lobulated, rounded, or polypoid in six patients. All underwent TBNA with a 21- or 22-gauge needle and endobronchial biopsy. The most frequent diagnosis was adenoid cystic carcinoma (4/11, 36%), followed by mucoepidermoid carcinoma (3/11, 27%), epithelial-myoepithelial carcinoma (2/11, 18%), oncocytoma (1/11, 9%), and hyalinizing clear cell carcinoma, salivary gland type (1/11, 9%). The surgical pathology specimens confirmed the diagnosis in all cases. CONCLUSIONS:To our knowledge, this is one of the largest cytomorphologic studies of primary salivary gland tumors of the tracheobronchial tree in the literature. Salivary gland tumors of the tracheobronchial tree are rare, and recognizing cytomorphologic changes that occur in salivary gland-type tumors is important for establishing a definitive diagnosis.
journal_name
Diagn Cytopatholjournal_title
Diagnostic cytopathologyauthors
Doxtader EE,Shah AA,Zhang Y,Wang H,Dyhdalo KS,Farver Cdoi
10.1002/dc.24285subject
Has Abstractpub_date
2019-11-01 00:00:00pages
1168-1176issue
11eissn
8755-1039issn
1097-0339journal_volume
47pub_type
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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abstract::We report the cytological and clinical findings of 16 fine-needle aspirates (FNAs) performed on recurrent (n = 6) and metastatic (n = 10) mixed mesodermal tumors (MMMTs). The median interval between the primary diagnosis and FNA was 16 mo. Primary sites were the endometrium (n = 11), the ovary (n = 3), the cervix (n =...
journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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更新日期:1997-03-01 00:00:00
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journal_title:Diagnostic cytopathology
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doi:10.1002/dc.21725
更新日期:2012-12-01 00:00:00
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
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