当前位置： SCI文献检索 > Journal of Contemporary Brachytherapy期刊下所有文献 > Carotid dosimetry after re-irradiation with 131Cs permanent implant brachytherapy in recurrent, resected head and neck cancer.

Carotid dosimetry after re-irradiation with 131Cs permanent implant brachytherapy in recurrent, resected head and neck cancer.

Abstract：

Purpose:Permanent seed implant cesium-131 (131Cs) brachytherapy provides highly localized radiation for patients with recurrent head and neck cancer (HNC), who may be ineligible for external beam radiation therapy due to a high-risk of toxicity. As carotid blowout is a concern in the setting of re-irradiation, a dose to the carotid artery was examined for 131Cs brachytherapy implants. Material and methods:Eleven patients were implanted with 131Cs adjacent to carotid at the time of resection for recurrent HNC. Vascularized tissue flaps were used in some patients. The carotid artery was contoured on the post-implant brachytherapy treatment plan, and the maximum carotid point dose and minimum carotid-seed distances are reported. The incidence of carotid blowout in the follow-up period was also measured. Results:The maximum carotid dose was 77 ±52 Gy (range, 3-158 Gy). The closest seed to the carotid artery was 0.8 ±0.8 cm (range, 0.2-2.6 cm). One patient without a flap experienced carotid blowout, which was attributed to a non-healing wound rather than to high radiation doses. Conclusions:Carotid artery doses from 131Cs are reported. Vascularized tissue flaps should be considered when planning 131Cs brachytherapy.

journal_name

J Contemp Brachytherapy

journal_title

Journal of contemporary brachytherapy

authors

Walsh A,Hubley E,Doyle L,Cognetti D,Curry J,Bar-Ad V,Luginbuhl A

doi

10.5114/jcb.2019.86298

subject

Has Abstract

pub_date

2019-06-01 00:00:00

pages

221-226

issue

3

eissn

1689-832X

issn

2081-2841

pii

37045

journal_volume

11

pub_type

杂志文章

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