Abstract:
Purpose:A feasibility study of 3D volume-based interstitial brachytherapy using thermoplastic polyether ether ketone (PEEK) catheters in advanced cervical cancer MR-based brachytherapy, when MR-compatible applicators are not available. Material and methods:Five cervical cancer patients received EBRT dose of 50 Gy in 25 fractions to whole pelvis using 3D conformal radiotherapy after standard pre-treatment evaluation. In our institute, interstitial brachytherapy (ISBT) is planned in BrachyVision TPS and routinely performed using stainless steel needles with Syed-Neblett template. Standard MR-compatible ISBT applicators were not available; therefore, the implant was carried out using PEEK catheters and Syed-Neblett template. The T1 and T2 MR and CT images of patients were acquired for treatment planning. Gross tumor volume (GTV), high-risk clinical target volume (HR-CTV), intermediate-risk clinical target volume (IR-CTV), and organs at risk (OARs) were delineated with the use of MR T2 weighted images, following GEC-ESTRO guidelines. Volumetric optimization was used for planning, and the treatment plan was executed with high-dose-rate (HDR) 192Ir Gammamed Plus device. Results:The dose prescribed to HR-CTV was 30 Gy low-dose-rate (LDR) equivalent (5 Gy × 4 fractions). Doses to target volume and OARs were analyzed using dose volume histogram (DVH). Dose values were biologically normalized to equivalent doses of 2 Gy fractions (EQD2). The average tumor volume was 67 cc and the average D90 of HR-CTV was 29 Gy (5.7 Gy/fraction) EQD2. D100 of HR-CTV volume was 18 Gy (3.8 Gy/fraction) EQD2. The total doses of 2 cc of rectum and bladder were 70 Gy and 76 Gy EQD2 (3.71 Gy and 4.04 Gy dose/fraction), respectively. Conclusions:When the facilities for MR-compatible applicators are not available, MR-based ISBT is feasible with PEEK catheters using available resources for advanced cervical cancer. Doses to HR-CTV and IR-CTV were achieved, restricting doses to OARs as per GEC-ESTRO guidelines.
journal_name
J Contemp Brachytherapyjournal_title
Journal of contemporary brachytherapyauthors
Palled SR,Tanvirpasha CAR,Naveen T,Sathiyan S,Kadirampatti G,Lokesh Vdoi
10.5114/jcb.2019.86975subject
Has Abstractpub_date
2019-08-01 00:00:00pages
307-311issue
4eissn
1689-832Xissn
2081-2841pii
37339journal_volume
11pub_type
杂志文章abstract:Purpose:To investigate the differences in prostate-specific antigen (PSA) bounce (PB) after high-dose-rate (HDR-BT) or low-dose-rate (LDR-BT) brachytherapy alone in prostate cancer patients. Materials and methods:Ninety-four patients with localized prostate cancer (T1-T2cN0), age ranged 50-81 years, were treated with ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2018.73786
更新日期:2018-02-01 00:00:00
abstract:Purpose:To evaluate clinical outcomes in patients with localized prostate cancer (LPC) treated with 3D conformal high-dose-rate (HDR) brachytherapy (BT) as monotherapy. Material and methods:From March 2004 to November 2017, 277 men with LPC underwent 3D conformal HDR-BT as monotherapy, with a temporary implant. The do...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2020.101685
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:To report the treatment effect of interstitial brachytherapy for abdominal wall metastases of ovarian cancer. MATERIAL AND METHODS:The patient is a 44-year-old female with a diagnosis of stage IA ovarian cancer. After surgery and two cycles of chemotherapy with paclitaxel and carboplatin, the patient noticed d...
journal_title:Journal of contemporary brachytherapy
pub_type:
doi:10.5114/jcb.2015.48574
更新日期:2015-02-01 00:00:00
abstract:Purpose:To report the results of INTERACTS (INTErventional Radiotherapy ACtive Teaching School) consensus conference on sarcoma interventional radiotherapy (brachytherapy). Material and methods:An international board of multidisciplinary experts was invited to a consensus conference on the state-of-the-art of sarcoma ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章,评审
doi:10.5114/jcb.2020.98120
更新日期:2020-08-01 00:00:00
abstract::Over the last twenty years major software and hardware developments in brachytherapy treatment planning, intraoperative navigation and dose delivery have been made. Image-guided brachytherapy has emerged as the ultimate conformal radiation therapy, allowing precise dose deposition on small volumes under direct image v...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章,评审
doi:10.5114/jcb.2010.16920
更新日期:2010-09-01 00:00:00
abstract:Purpose:Graphical optimization (GO) and inverse planning simulated annealing (IPSA) are the main treatment planning optimization techniques used in patients undergoing 3D brachytherapy treatment. This study aims to compare the dosimetric difference of plans optimized by GO and IPSA in cervical cancer brachytherapy. Ma...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2019.87145
更新日期:2019-08-01 00:00:00
abstract:Purpose:This research aims to evaluate the effectiveness and safety of a robot-assisted 3D personalized template in 125I seed brachytherapy of thoracoabdominal tumors. Material and methods:Forty-three patients with different tumors were involved in this research between 2013 and 2015. They were all eligible to 125I se...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2018.77957
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:To compare the short-term toxicity and dosimetry of tandem and ring (TR), and tandem and ovoid (TO) applicators in treatment of gynecologic malignancy. MATERIAL AND METHODS:Following pelvic external beam radiation therapy (EBRT), a total of 52 computed tomography-based plans from 13 patients with cervical canc...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2015.51853
更新日期:2015-06-01 00:00:00
abstract:Purpose:To evaluate the impact of supplemental external beam radiation therapy (EBRT) prior to permanent prostate brachytherapy on long term urinary, bowel, and erectile function. Material and methods:Patient administered urinary, bowel, and erectile quality of life (QoL) instrument were obtained prior to treatment an...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2017.70763
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:Standard treatment plan libraries are often used to ensure a quick turn-around time for vaginal cylinder treatments. Recently there is increasing interest in transitioning from conventional 2D radiograph based brachytherapy to 3D image based brachytherapy, which has resulted in a substantial increase in treatme...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2012.29365
更新日期:2012-06-01 00:00:00
abstract:Purpose:Permanent seed implant cesium-131 (131Cs) brachytherapy provides highly localized radiation for patients with recurrent head and neck cancer (HNC), who may be ineligible for external beam radiation therapy due to a high-risk of toxicity. As carotid blowout is a concern in the setting of re-irradiation, a dose t...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2019.86298
更新日期:2019-06-01 00:00:00
abstract:Purpose:Skin cancers are the most common human malignancy with increasing incidence. Currently, surgery is standard of care treatment for non-melanoma skin cancers. However, brachytherapy is a growing modality in the management of skin cancers. Therefore, we aimed to assess the outcome of patients with non-melanoma ski...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2018.75596
更新日期:2018-04-01 00:00:00
abstract:PURPOSE:Radiotherapy for breast cancer includes different techniques and methods. The purpose of this study is to compare dosimetric calculations using TG-43 dose formalism and Varian Acuros™ BV (GBBS) dose calculation algorithm for interstitial implant of breast using metal catheters in high-dose-rate (HDR) brachyther...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2015.54052
更新日期:2015-08-01 00:00:00
abstract::Cervical cancer (CC) is a neoplasm with great potential for prevention, but it is still an important public health problem in most developing countries. No significant difference is found in the literature between intracavitary high-dose-rate (HDR) and low-dose-rate (LDR) brachytherapy, when considering overall, disea...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章,评审
doi:10.5114/jcb.2018.81027
更新日期:2018-12-01 00:00:00
abstract:Purpose:To evaluate dose-volume relationships of target volume and critical structures in computed tomography (CT) image-based brachytherapy for head and neck cancer. Material and methods:Thirty-seven patients with mobile tongue, floor of mouth, and base of tongue cancer treated with brachytherapy (post-operative alon...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2017.72581
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:The aim of this work was to determine dose distributions for high-energy brachytherapy sources at spatial locations not included in the radial dose function gL(r) and 2D anisotropy function F(r,θ) table entries for radial distance r and polar angle θ. The objectives of this study are as follows: 1) to evaluate ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2010.13715
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:The common use of nomograms in Low Dose Rate (LDR) permanent prostate brachytherapy (BT) allows to estimate the number of seeds required for an implant. Independent dosimetry verification is recommended for each clinical dosimetry in BT. Also, nomograms can be useful for dose calculation quality assurance and t...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2011.24817
更新日期:2011-09-01 00:00:00
abstract:Purpose:The aim of this study was to propose an index for evaluating dosimetric impact of inter-observer target delineation variability in brachytherapy. Material and methods:The coverage with dosimetric concordance index (CDCI) is expressed as CDCIcommon and CDCIpair. The CDCIcommon is the mean coverage of target vol...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2020.94309
更新日期:2020-04-01 00:00:00
abstract:Purpose:To quantify the reduction of relative displacement between the implanted intracavitary applicator and the patient bony anatomy, due to the use of a hover transport system during the patient transports between the imaging table and the treatment table. Material and methods:The displacement of the applicator ins...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2018.73755
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:To study the safety and efficacy of high-dose-rate interstitial brachytherapy (HDRIBT) in patients with liver metastases (LM). MATERIAL AND METHODS:Between 2009 and 2011, 10 patients with 12 metastatic lesions in the liver were enrolled in this prospective trial. All patients had either refused surgery or foun...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2013.36175
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:The object of this study was to analyze the outcome of salvage HDR brachytherapy treatment after local failure, for patients with prostate specific antigen (PSA) failure without distant metastasis, after external beam radiation and HDR brachytherapy treatment, or after radical prostatectomy, with or without hor...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:
更新日期:2009-06-01 00:00:00
abstract:PURPOSE:During intracavitary brachytherapy (ICBT) for cervical cancer, the choice of applicator system remains rather arbitrary. However, as the applicator geometry may play an important role in dose distribution, thereby improving the therapeutic ratio, this study was conducted to compare the Manchester-style and Flet...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2012.32555
更新日期:2012-12-01 00:00:00
abstract:Purpose:Increased complexity of interventional radiotherapy (brachytherapy - BT) treatment planning and quality control procedures has led to the need of a specific training. However, the details of the features of BT learning objectives and their distribution in the training paths of the Italian Radiation Oncology Sch...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章,评审
doi:10.5114/jcb.2019.83137
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:To explore patterns of time to failure in men receiving high doses of permanent seed brachytherapy with or without external beam radiation therapy as a function of risk status. MATERIAL AND METHODS:Two thousand two hundred and thirty four patients were treated with prostate brachytherapy with median follow up ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2013.39210
更新日期:2013-12-01 00:00:00
abstract:Purpose:To verify the accuracy and efficacy of three-dimensional printing individual template (3D-PIT) with computed tomography-magnetic resonance imaging (CT-MRI) fusion for radioactive iodine-125 (125I) seed implantation in high-grade brain gliomas. Material and methods:Between June 2017 and June 2018, 16 patients w...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2019.85729
更新日期:2019-06-01 00:00:00
abstract::In order to improve oncologic outcomes in radiotherapy treatments of patients with unresectable pelvic sidewall recurrences of uterine cervical cancer, we combined high-dose-rate interstitial brachytherapy (HDR-ISBT) with newly tested hypoxic radiosensitizer Kochi oxydol-radiation therapy for unresectable carcinomas (...
journal_title:Journal of contemporary brachytherapy
pub_type:
doi:10.5114/jcb.2020.101695
更新日期:2020-12-01 00:00:00
abstract:Purpose:Inadequate procedural training is of increasing concern in resident training, especially in prostate brachytherapy (PB). Transperineal rectal spacer placement (TRSP) requires many of the same proficiencies as PB. This work describes the assessment of teaching techniques focusing on developing critical competenc...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2019.90984
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:Dose coverage is crucial for successful treatment in mono-brachytherapy. Since few and very high dose fractions are used, there is an important balance between dwell positioning outside the clinical target volume (CTV) and possible damage on adjacent normal tissue. The purpose of this study was to evaluate the ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2014.45586
更新日期:2014-10-01 00:00:00
abstract:Purpose:We present a case report of treatment using interstitial and surface high-dose-rate (HDR) brachytherapy for cutaneous squamous cell carcinoma (SCC) involving the interspace of the third and fourth digits. The patient refused two-ray amputation and the lesion was not amenable for external beam radiation therapy ...
journal_title:Journal of contemporary brachytherapy
pub_type:
doi:10.5114/jcb.2020.92408
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:The incidence of non-melanoma skin cancer (NMSC) has been increasing over the past 30 years. Basal cell carcinoma and squamous cell carcinoma are the two most common subtypes of NMSC. The aim of this study was to estimate tumour control, toxicity, and aesthetic events in elderly patients treated with high-dose-...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2015.55746
更新日期:2015-12-01 00:00:00