Abstract:
OBJECTIVE:To evaluate the effect of vaccine hesitancy screening on childhood vaccine uptake. METHODS:We conducted a cluster randomized controlled trial in pediatric primary care clinics in Washington state. Vaccine-hesitant parents (VHPs) with a healthy newborn receiving health supervision at participating clinics were eligible. VHPs were identified by using a 4-item version of the validated Parent Attitudes About Childhood Vaccines Survey (PACV). Before their child's 2- and 6-month health supervision visits, VHPs at intervention clinics completed the 15-item PACV embedded in a survey containing placebo items. Intervention providers received a summary of parents' 15-item PACV responses and interpretation of their PACV score; discretion was given to providers regarding how they acted on this information. VHPs at control clinics completed only the placebo survey items, and their child's provider received a summary of their responses; control providers remained blinded to parent VHP status. Our outcome was child immunization status at 8 months of age expressed as percent of days underimmunized. We compared outcomes in control and intervention participants using t test and linear mixed-effects regression. RESULTS:We enrolled 24 clinics (12 in each arm) and 156 parents (65 in the intervention arm). Parent characteristics were similar across arms except more intervention (versus control) parents had a first-born child (60.9% vs 44%; P = .04). No significant difference in outcome was detected between arms (25.2% [95% confidence interval: 16.0% to 34.5%] vs 19.1% [95% confidence interval: 12.0% to 26.3%] mean days underimmunized in the intervention and control arms, respectively). CONCLUSION:Vaccine hesitancy screening was not significantly associated with days underimmunized.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Opel DJ,Henrikson N,Lepere K,Hawkes R,Zhou C,Dunn J,Taylor JAdoi
10.1542/peds.2019-0802subject
Has Abstractpub_date
2019-11-01 00:00:00issue
5eissn
0031-4005issn
1098-4275pii
peds.2019-0802journal_volume
144pub_type
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