Abstract:
AIMS:Phelan-McDermid syndrome (PMD) is a congenital syndrome caused by a deletion on chromosome 22q13.3. About 600 cases have been identified worldwide. PMD is characterized by neonatal hypotonia, moderate/severe intellectual impairment, impaired expressive language, and typical dysmorphic features. Psychological symptoms as hyperactivity, attention problems, restlessness, and stereotyped-repetitive behavior were reported. The aim of the study was to assess incontinence and associated psychological problems in PMD. METHODS:Forty-one individuals with PMD were recruited through a German support group (48.8% male; mean age 13.4 years; range, 4-55 years). Parents or caregivers completed the developmental behavior checklist (DBC), as well as the parental questionnaire: enuresis/urinary incontinence, including six questions on adaptive toileting skills. RESULTS:Rates of nocturnal enuresis (NE), daytime urinary incontinence, and fecal incontinence were 86%, 73%, and 79%. Rates were similar in all age groups (children, teens, adults). Constipation was present in 19%. Forty-two percent of the sample had a clinically relevant DBC score, with adults more affected than teens. Persons with NE had significantly higher "anxiety/depression" subscale scores. Toileting skills were more developed in adults than in children. Sixty-eight percent had further physical disabilities. CONCLUSIONS:Incontinence rates in PMD are high in all age groups. However, persons with PMD can improve their toilet skills. Therefore, the assessment and treatment of incontinence in persons with PMD is recommended. Constipation does not seem to be a major problem in PMD. Due to the high prevalence rates of somatic conditions, an assessment for organic and functional incontinence is recommended.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
Hussong J,Wagner C,Curfs L,von Gontard Adoi
10.1002/nau.24197subject
Has Abstractpub_date
2020-01-01 00:00:00pages
310-318issue
1eissn
0733-2467issn
1520-6777journal_volume
39pub_type
杂志文章abstract::Polypropylene (PP) mesh has been used as a primary or adjuvant material for vaginal reconstruction for both stress urinary incontinence (SUI) and pelvic organ prolapse (POP) for decades. Whether polypropylene is the optimal material for such indications has been called into question by clinicians, regulatory agencies ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.24312
更新日期:2020-07-01 00:00:00
abstract:AIMS:The aim of the study was to compare the effect of hypopressive exercises including pelvic floor muscle contraction, pelvic floor muscle training (PFMT) alone and control on pelvic floor muscle function in women with pelvic organ prolapse (POP). METHODS:Fifty-eight women with a mean age of 55.4 (± 9.8) years old w...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.21149
更新日期:2012-01-01 00:00:00
abstract:AIMS:This article aims to identify quality control (QC) best practice, to review published QC audits in order to identify how closely good practice is followed, and to carry out a market survey of the software features that support QC offered by urodynamics machines available in the UK. METHODS AND RESULTS:All UK dist...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.21133
更新日期:2011-11-01 00:00:00
abstract:AIMS:The ultrasound assessment of bladder wall thickness (BWT) and intravesical prostatic protrusion (IPP) have emerged as a non-invasive, inexpensive, time-saving alternatives to pressure-flow studies to assess benign prostatic obstruction (BPO). Aim of our study was to evaluate the effect on detrusor mass of dutaster...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23247
更新日期:2017-11-01 00:00:00
abstract::Myelin basic protein (MBP) can be used as an antigen for inducing experimental allergic encephalomyelitis (EAE). In various studies, EAE animals have been used as an experimental model of demyelinating diseases. The aim of this study was to determine whether EAE, induced by MBP in rats, can be useful for investigation...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/1520-6777(2000)19:6<689::aid-nau7>3.0.co;2
更新日期:2000-01-01 00:00:00
abstract:AIMS:Urgency is a key symptom in the diagnosis of overactive bladder (OAB), yet its definition and measurement are subject to continuing debate whether urinary urgency is a pathologic sensation or an intensification of normal desire to pass urine. The objective of this research was to explore the concept of urgency amo...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21242
更新日期:2012-04-01 00:00:00
abstract::The aim of the present study was to determine to what extent adult rats can produce new contracting bladder muscle and to see if such newly formed bladder tissue possesses characteristic mechanical properties or whether the ability to recover mechanically is so pronounced that the prehistory of the bladder is unimport...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1020
更新日期:2001-01-01 00:00:00
abstract::The prevalence of lower urinary tract (LUT) symptoms increases with age but the etiology is unknown. This article aims to identify research directions that clarify the basis of this association. The initial question is whether biological age is the variable of interest or a time-dependent accumulation of factors that ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.23035
更新日期:2017-04-01 00:00:00
abstract:AIM:To characterise the developmental changes to the normal bladder by examining the in vitro contractile properties of the fetal sheep detrusor smooth muscle bladder at different gestational ages. METHODS:Three groups of normally developing fetal sheep bladders were investigated: (1) 65-70 days gestation (2nd trimest...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20124
更新日期:2005-01-01 00:00:00
abstract:AIMS:To evaluate the efficacy, safety, and tolerability of repetitive Transcranial Magnetic Stimulation (rTMS) associated with standard drug therapies for neuropathic pain that does not respond to pharmacological treatment alone in patients with Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC). Secondary goals were...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.23718
更新日期:2018-11-01 00:00:00
abstract:AIMS:Prostate cancer is the most frequently diagnosed male cancer and urinary incontinence represents a major consequence following surgery. Penile compression clamps (PCCs) which externally occlude the urethra may be used to manage the incontinence. Despite potential complication of PCCs, such as deformation-inflicted...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23172
更新日期:2017-08-01 00:00:00
abstract:AIMS:We evaluated the long-term results with a left antegrade continence enema (LACE) approach: "Macedo-Malone (MM) procedure" to define parameters such as clinical durability of the technique and patients' compliance with the method. METHODS:We reviewed the medical records of all patients that underwent the MM proced...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22880
更新日期:2017-01-01 00:00:00
abstract::Experiments to investigate restoration of lower urinary tract control by electrical stimulation of the sacral nerve roots are mostly performed on dogs, yet little morphometric data (such as canine root and fiber diameter distributions) are available. The aim of this study was to acquire morphometric data of the intrad...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(SICI)1520-6777(1996)15:3<235::AID-NAU8>3.
更新日期:1996-01-01 00:00:00
abstract:AIMS:De novo stress urinary incontinence (SUI) may develop after surgical correction of advanced pelvic organ prolapse (POP) in otherwise continent women. Prediction of which women with POP will develop SUI after the prolapse is corrected is difficult. We aimed to externally validate a previously described prediction m...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24608
更新日期:2021-01-25 00:00:00
abstract:AIMS:The purpose of this scoping review was to examine research activity comparing suprapubic catheterization to any other method of chronic bladder emptying such as intermittent and indwelling catheterization in adults in relation to complications, patient satisfaction, and health-related quality of life (QoL). METHO...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.22356
更新日期:2013-09-01 00:00:00
abstract:AIMS:To review the known determinants of healthcare-seeking behavior for LUTS and address unmet needs and future research priorities. METHODS:The PubMed literature was searched for currently known factors affecting treatment seeking for LUTS, OAB, and incontinence in men and women. RESULTS:Further to the great variat...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.22212
更新日期:2012-03-01 00:00:00
abstract:AIMS:Urodynamic studies (UDS) are complex, invasive and may be emotionally and physically distressing. Inadequate information may heighten distress. Prior to UDS, our patients receive written and verbal information, yet concerns remains that some women may not be adequately informed. This study examined how informed wo...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21014
更新日期:2011-04-01 00:00:00
abstract::The response of the abdominal muscles to voluntary contraction of the pelvic floor (PF) muscles was investigated in women with no history of symptoms of stress urinary incontinence to determine whether there is co-activation of the muscles surrounding the abdominal cavity during exercises for the PF muscles. Electromy...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/1520-6777(2001)20:1<31::aid-nau5>3.0.co;2-
更新日期:2001-01-01 00:00:00
abstract:AIMS:To investigate the role of beta-adrenoceptor subtypes in mediating relaxation of the pig bladder trigonal muscle in vitro. MATERIALS AND METHODS:Longitudinal strips of trigonal muscle were isolated, and the mucosa and serosa removed. Tissues were precontracted with KCl, and beta-adrenoceptor agonists (isoprenalin...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.10130
更新日期:2003-01-01 00:00:00
abstract:AIM:The aim of the study was to assess correlations between body parameters and bladder capacity in healthy schoolboys and schoolgirls. On the basis of those anthropometric data functional bladder capacity (FBC) in children was estimated. MATERIALS AND METHODS:The questionnaires were sent to 1,055 parents of children ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20123
更新日期:2006-01-01 00:00:00
abstract:AIMS:In the bladder, ATP is an important signaling molecule, which is released by bladder stretch and acid. We hypothesized that ATP might play a unique role in patients with OAB, characterized by low bladder volumes at first desire to void (FDV) and maximal cystometric capacity (MCC) and symptoms of frequency/urgency ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22344
更新日期:2013-09-01 00:00:00
abstract::The vaginal vestibule has not been the subject of a dedicated journal article. Recent terminology has suggested its division into anterior and posterior components. The case for this division has not yet been assessed. Both components extend laterally from the hymen to the junction with the labia minora. The posterior...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23064
更新日期:2017-04-01 00:00:00
abstract:AIMS:The objective of the study was to compare sacral nerve stimulation (SNS) to pudendal nerve stimulation (PNS) for voiding dysfunction. METHODS:Thirty subjects with voiding dysfunction had a tined lead placed at S3 and a second electrode implanted at the pudendal nerve via a posterior approach. In a blinded, random...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.20174
更新日期:2005-01-01 00:00:00
abstract:AIMS:Lower urinary tract dysfunction affects up to 75% of the multiple sclerosis population. Results from our recent Pilot Study (McClurg et al., 2006) indicated that a combined programme of pelvic floor muscle training, electromyography biofeedback and neuromuscular electrical stimulation modalities may alleviate some...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.20486
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:Women with urodynamic stress incontinence (USI) have lower opening and closing detrusor pressures than women without USI. This study was undertaken to determine whether a change occurs in opening and closing detrusor pressures after colposuspension, whether cure is associated with change, and whether age infl...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.10165
更新日期:2004-01-01 00:00:00
abstract:AIMS:To investigate whether vaginal estrogen cream combined with tolterodine is more effective than tolterodine alone in the treatment of postmenopausal women with overactive bladder (OAB). MATERIALS AND METHODS:This is an unblinded study without placebo. A preliminary study consisted of tolterodine 2 mg twice per day...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.20583
更新日期:2009-01-01 00:00:00
abstract:AIMS:The Urogenital Distress Inventory (UDI-6) and Incontinence Impact Questionnaire (IIQ-7) assess symptom distress and the impact on daily life of urinary incontinence. The UDI-6 has not been validated before in males. Our aim was to validate the UDI-6 and IIQ-7 in Dutch men and women. METHODS:The translation to Dut...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22496
更新日期:2015-01-01 00:00:00
abstract:AIMS:Overactive bladder (OAB), characterized by urinary urgency, with or without incontinence, and urinary frequency and nocturia, has a significant impact on patients' lives. Given the social context inherent in OAB, the purpose of this study was to identify issues faced by OAB family members. METHODS:Incontinent OAB...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20705
更新日期:2009-01-01 00:00:00
abstract:AIM:To elucidate the precise cellular and molecular mechanisms that underlie urethral fibrogenesis. METHODS:Endoluminal electrocautery injury (using Karl Storz 10 Fr. Pediatric urethroscope) was employed in male rabbits (n = 6) to create mucosal injury. Retrograde urethrogram (RUG) and endoluminal ultrasound technique...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24281
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:The brain's role in continence is critical but poorly understood. Although regions activated during bladder stimulation have been identified, little is known about the interaction between regions. In this secondary analysis we evaluate resting state and effective connectivity in older women treated for urgen...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23766
更新日期:2018-11-01 00:00:00