Abstract:
AIM:To characterise the developmental changes to the normal bladder by examining the in vitro contractile properties of the fetal sheep detrusor smooth muscle bladder at different gestational ages. METHODS:Three groups of normally developing fetal sheep bladders were investigated: (1) 65-70 days gestation (2nd trimester); (2) 105-110 days (3rd trimester); (3) 135-140 days (term). Isometric contractions in isolated detrusor strips were measured during either electrical field stimulation (EFS) or exposure to agonists: carbachol, alpha-beta methylene-ATP (ABMA) and KCl. RESULTS:There was a significant increase of absolute force elicited by EFS with fetal age. Contractures elicited by carbachol, ABMA and KCl increased between Groups 1 and 2, but not thereafter. The proportional increase of contractions elicited by carbachol and ABMA was also greater between Groups 1 and 2, than for EFS and KCl. CONCLUSIONS:Fetal development between 65 and 140 days in the sheep is associated with increased contractile activation. The data are consistent with an increase of muscle development in the earlier stages (65-110 days). In the later stage (110-140 days) muscle development is complete but functional innervation of the tissue continues.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
Nyirády P,Thiruchelvam N,Godley ML,David A,Cuckow PM,Fry CHdoi
10.1002/nau.20124subject
Has Abstractpub_date
2005-01-01 00:00:00pages
276-81issue
3eissn
0733-2467issn
1520-6777journal_volume
24pub_type
杂志文章abstract:AIMS:To evaluate neuromodulation outcomes in patients with prior back surgery. METHODS:Adults in our prospective observational sacral/pudendal neuromodulation study were retrospectively evaluated. History and operative details were reviewed, and outcomes were measured at 3, 6, 12, and 24 months with overactive bladder...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
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abstract:AIMS:Phelan-McDermid syndrome (PMD) is a congenital syndrome caused by a deletion on chromosome 22q13.3. About 600 cases have been identified worldwide. PMD is characterized by neonatal hypotonia, moderate/severe intellectual impairment, impaired expressive language, and typical dysmorphic features. Psychological sympt...
journal_title:Neurourology and urodynamics
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abstract::Estrogens are known to have a major role in the function of the lower urinary tract although the role of exogenous estrogen replacement therapy in the management of women with lower urinary tract dysfunction remains controversial. Whilst for many years systemic and vaginal estrogen therapy was felt to be beneficial in...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
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更新日期:2014-09-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22762
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abstract:AIMS:No one has assessed urodynamic studies (UDS) to determine those steps that elicit the greatest anxiety, distress, and pain in children. We sought to systematically evaluate a child's UDS experience to mollify these reactions. METHODS:Prospective study involving children aged ≥5 undergoing UDS over a 6-month perio...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
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abstract::The mechanism by which the ureteropelvic junction (UPJ) regulates the passage of urine from the renal pelvis to the ureter, and prevents urinary backflow from the the ureter to the renal pelvis, is not completely understood. The current communication studies this mechanism in 18 dogs. With the dogs under anesthesia, n...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(sici)1520-6777(1997)16:4<315::aid-nau7>3.
更新日期:1997-01-01 00:00:00
abstract:AIMS:The primary aim of this prospective study was to examine the correlations between "The International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF)" score and urodynamic findings in patients with urge incontinence. In addition, we aimed to observe the alterations of these parameters with antimusca...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20389
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(sici)1520-6777(2000)19:2<137::aid-nau4>3.
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journal_title:Neurourology and urodynamics
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
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abstract:AIMS:External sphincterotomy (ES) is a therapeutic option for male spinal cord injury patients with detrusor sphincter dyssynergia. However, some patients need to change their voiding management after ES. One of the potential causes of failure is reportedly detrusor dysfunction, but long-term urodynamic follow-up data ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
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abstract:BACKGROUND:The brain's role in continence is critical but poorly understood. Although regions activated during bladder stimulation have been identified, little is known about the interaction between regions. In this secondary analysis we evaluate resting state and effective connectivity in older women treated for urgen...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23766
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abstract:AIMS:Due to a paucity of evidence-based guidelines, anecdotal practice patterns often dictate clinical management of recurrent urinary tract infection (UTI) in women. Our aim was to identify pathologic findings of the urinary tract through cystoscopy and imaging in women with recurrent UTI, and to determine if specific...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22998
更新日期:2017-03-01 00:00:00
abstract:AIMS:To evaluate long-term anatomical and functional outcomes of the transobturator-infracoccygeal hammock repair for complex genital prolapse with a porcine collagen-coated polypropylene mesh. METHODS:A prospective observational study comparing pre- and postoperative outcomes, using pelvic organ prolapse quantificati...
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doi:10.1002/nau.20956
更新日期:2011-03-01 00:00:00
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更新日期:2019-06-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22687
更新日期:2016-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23232
更新日期:2017-11-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20311
更新日期:2007-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21181
更新日期:2012-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/nau.10165
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pub_type: 杂志文章
doi:10.1002/nau.23263
更新日期:2017-11-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20654
更新日期:2009-01-01 00:00:00
abstract::In our hospital, we have followed a group of patients with familial amyloidotic polyneuropathy (FAP), type I. This disease is characterized by a progressive sensitive-motor and autonomic polyneuropathy. The amyloid fibrils of FAP I contain a mutant transthyretin (TTR) molecule. More than 90% of TTR production occurs i...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/(sici)1520-6777(1997)16:1<55::aid-nau7>3.0
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.2198
更新日期:2002-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.21243
更新日期:2012-06-01 00:00:00
abstract::Forty-six patients were evaluated for complaints of urinary incontinence or voiding disorders. Diagnostic testing included a detailed history, physical examination, urine analysis, and urodynamic studies consisting of a conventional urodynamic test (S.I.) including provocative manoeuvres and extramural ambulatory urod...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/1520-6777(1994)13:3<237::aid-nau1930130305
更新日期:1994-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20988
更新日期:2011-09-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/nau.22406
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:There is a lack of evidence to assess whether gait functionality can be affected by the condition of the pelvic floor musculature in patients with multiple sclerosis (MS). OBJECTIVE:To evaluate the relationship between pelvic floor functionality and general functional performance, and also their relationshi...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24314
更新日期:2020-03-01 00:00:00
abstract:AIMS:To determine the optimal stochastic whole body vibration (SR-WBV) load modality regarding pelvic floor muscle (PFM) activity in order to complete the SR-WBV training methodology for future PFM training with SR-WBV. METHODS:The continuous and the intermittent SR-WBV modalities were tested by means of electromyogra...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.21251
更新日期:2012-06-01 00:00:00