Abstract:
AIMS:To evaluate long-term anatomical and functional outcomes of the transobturator-infracoccygeal hammock repair for complex genital prolapse with a porcine collagen-coated polypropylene mesh. METHODS:A prospective observational study comparing pre- and postoperative outcomes, using pelvic organ prolapse quantification (POP-Q) measurements, pelvic floor distress inventory (PFDI), and pelvic floor impact questionnaire (PFIQ) scores. RESULTS:One hundred fourteen women with recurrent, advanced, or posthysterectomy genital prolapse were enrolled. During follow-up (median value 57 months), 101 patients were available for assessment. Overall anatomical success rate was 96%, with significant improvement in quality-of-life. Three patients experienced symptomatic recurrent posterior prolapse. Seven had persistent stress urinary incontinence. Mesh exposure occurred in 6.9% of cases, including an infected hematoma that required partial excision of the mesh. No severe adverse event or change in sexual function was observed. CONCLUSIONS:The transobturator-infracoccygeal hammock is well tolerated with effective long-term anatomical and functional results for complex genital prolapse. In our experience and compared to the data of the literature, the use of collagen-coated versus uncoated polypropylene meshes seems to decrease local morbidity.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
Sergent F,Resch B,Al-Khattabi M,Ricbourg A,Schaal JP,Marpeau Ldoi
10.1002/nau.20956subject
Has Abstractpub_date
2011-03-01 00:00:00pages
384-9issue
3eissn
0733-2467issn
1520-6777journal_volume
30pub_type
杂志文章abstract::The prevalence of lower urinary tract (LUT) symptoms increases with age but the etiology is unknown. This article aims to identify research directions that clarify the basis of this association. The initial question is whether biological age is the variable of interest or a time-dependent accumulation of factors that ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.23035
更新日期:2017-04-01 00:00:00
abstract::The International Continence Society Benign Prostatic Hyperplasia Study (ICS-BPH) was devised in response to the perceived underutilization of urodynamics in the diagnosis of benign prostatic obstruction (BPO), together with the apparent reliance on symptoms alone when selecting patients for invasive therapies, despit...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract:AIMS:The importance of the T- and L-type Ca(2+) channels on the alpha(1)-adrenoceptor-mediated contraction of guinea-pig vas deferens was investigated in relation to the SK and BK channels. METHODS:Isometric contractile response to electrical stimulation (ES) of 50 pulses at 40 Hz was recorded. ES responses were modul...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20654
更新日期:2009-01-01 00:00:00
abstract::Following use of botulinum toxin in the 1980s for the treatment of detrusor sphincter dyssynergia in patients with spinal cord injury (SCI), the potential therapeutic value of this neurotoxin in urology has been the subject of much interest. The DIGNITY (Double-blind InvestiGation of purified Neurotoxin complex In neu...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.22630
更新日期:2014-07-01 00:00:00
abstract:AIMS:We examined the mechanism of action of naftopidil, an α1D/A blocker, on spinal descending serotonergic neurotransmission for the micturition reflex. METHODS:We examined (1) urinary 5-hydroxyindole acetic acid (5-HIAA) after intraperitoneal administration of saline, para-chlorophenylalanine (PCPA; a serotonin synt...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23028
更新日期:2017-03-01 00:00:00
abstract:AIMS:P(2)X(3) (ATP-gated receptors) in nociceptive neurons of dorsal root ganglion (DRG) participate in transmission of pain signals from the periphery to the spinal cord. However, the role of P(2)X(3) receptors in chronic prostate pain and continued intractable pain remains unclear. MATERIALS AND METHODS:We examined ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21060
更新日期:2011-04-01 00:00:00
abstract:AIM:Even though many agents have been implicated as modulators of ureteral contractile activity, the exact mechanisms that control human ureteral smooth muscle contractility have yet to be clearly defined. Recently, Rho-kinase has been reported to be involved in the contractile mechanism of smooth muscles in various or...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20096
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:Patient-reported outcome (PRO) instruments are useful for assessing treatment success in patients with overactive bladder (OAB). PROs such as the OAB Questionnaire (OAB-q) and Patient Perception of Bladder Condition (PPBC) focus more on OAB symptoms than satisfaction. We describe the development of the Pat...
journal_title:Neurourology and urodynamics
pub_type: 临床试验,杂志文章
doi:10.1002/nau.20890
更新日期:2011-01-01 00:00:00
abstract:AIM:NK-1 receptors in sensory nerves, the spinal cord and bladder smooth muscle participate in complex sensory mechanisms that regulate bladder activity. This study was designed to assess the efficacy and safety of a new NK-1 receptor antagonist, netupitant, in patients with OAB. METHODS:This was a phase II, multicent...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/nau.22406
更新日期:2014-03-01 00:00:00
abstract:AIMS:Progressive weakness in pelvic floor tissues is extremely common and leads to the distressing problems of stress urinary incontinence (SUI) and pelvic organ prolapse (POP). There has been extensive work on a vast array of materials spanning synthetics, autografts, allografts, and xenografts. Uniaxial testing of ma...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.21156
更新日期:2012-01-01 00:00:00
abstract:AIMS:To determine the distributions of bothersome and non-bothersome nocturnal voiding and the differences between them using a community-based study. SUBJECTS AND METHODS:A total of 2,205 men and women aged 41-70 years from three Japanese towns responded to our postal questionnaire survey. The questionnaire included ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20451
更新日期:2007-01-01 00:00:00
abstract:AIMS:The aim of this study was to assess medium-term outcomes of the single anterior vaginal wall incision technique with concomitant mid-urethral sling (MUS) procedure. METHODS:Patients suffering from stress urinary incontinence and who desired surgical correction for their incontinence were divided into two groups a...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22847
更新日期:2016-11-01 00:00:00
abstract::We created gradual partial urethral obstruction in 20 guinea pigs using silver jeweler's jump rings. After 4 or 8 weeks obstruction all animals underwent cystometry and were assigned to one of five urodynamic categories: normal, high pressure voiding, unstable, low compliance, or decompensated. After sacrifice, the co...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930120607
更新日期:1993-01-01 00:00:00
abstract:AIMS:The use of botulinum toxin A (BoNT/A) is commonplace now in the management of refractory overactive bladder and neurogenic detrusor overactivity (NDO). Despite one formulation now having a license, the full mechanism of action is not fully understood. Furthermore practice varies worldwide in the way the toxin is d...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.22797
更新日期:2016-02-01 00:00:00
abstract:AIM:To perform a systematic review summarizing the knowledge of genetic variants, gene, and protein expression changes in humans and animals associated with urgency urinary incontinence (UUI) and to provide an overview of the known molecular mechanisms related to UUI. METHODS:A systematic search was performed on March...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.24512
更新日期:2020-11-01 00:00:00
abstract:AIMS:Nociceptive behavior and its relationship with bladder dysfunction were investigated in two cystitis models, which were induced by intraperitoneal (i.p.) injection of cyclophosphamide (CYP) or intravesical instillation of acetone, using freely moving, non-catheterized conscious rats. METHODS:Female Sprague-Dawley...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20777
更新日期:2010-03-01 00:00:00
abstract:INTRODUCTION:Isaacs's syndrome (IS), is a rare neurological disorder, characterized by sustained muscular activity, fasciculations, cramps, myokymia, excessive sweating, and occasional elevation of creatine phosphokinase (CPK) enzyme. AIM:To report our experience in patients with IS and urinary manifestations, describ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23336
更新日期:2018-01-01 00:00:00
abstract:AIMS:Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic disease, which is difficult to treat. Patients usually seek for new therapies and might not follow-up regularly. This study investigated long-term symptom changes in patients with IC/BPS, especially in those who were lost to follow-up. METHODS:We e...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24104
更新日期:2019-09-01 00:00:00
abstract:METHODS:We estimated the prevalence of CIC use in the United States using a neurogenic population, consisting of persons with multiple sclerosis, spina bifida, and spinal cord injury. We measured catheter samples to obtain the amount of waste per catheter. RESULTS:At least 300 800 persons in the United States perform ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23562
更新日期:2018-09-01 00:00:00
abstract:AIMS:To evaluate the reliability, validity, and predicted probabilities of a Chinese version of the Dysfunctional Voiding Symptom Score (DVSS) and to explore the latent factors underlying dysfunctional voiding. MATERIALS AND METHODS:We enrolled 60 children (38 girls and 22 boys) with a diagnosis of dysfunctional voidi...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22254
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:As increasing evidence suggest that α(1)-blockers prevent benign prostatic hyperplasia related overactive bladder and nocturia in the human, we investigated the effects of silodosin and naftopidil on hypertension-related bladder dysfunction in the spontaneously hypertensive rat (SHR) model. MATERIALS AND METHO...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22297
更新日期:2013-04-01 00:00:00
abstract:AIMS:Resiniferatoxin (RTX), a vanilloid compound and agonist of the transient receptor potential channel 1 (TRPV1), is known for its beneficial effects on neurogenic detrusor overactivity. The mainstream rationale for its use is the desensitization of TRPV1 on sensory bladder afferents. However, recent findings showed ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20313
更新日期:2007-01-01 00:00:00
abstract:AIMS:The aim of this study was to resolve the paradox as to whether magnetic stimulation of sacral nerve roots results in contraction or suppression of the bladder, in both normal individuals and patients with spinal cord injury (SCI). MATERIALS AND METHODS:Seven males with complete SCI and neurogenic detrusor overact...
journal_title:Neurourology and urodynamics
pub_type: 临床试验,杂志文章
doi:10.1002/nau.20009
更新日期:2004-01-01 00:00:00
abstract:AIMS:We studied preoperative and postoperative pressure transmission ratio (PTR) and urethral pressure profilometry in patients undergoing the vaginal wall patch sling technique as a first surgical approach for genuine stress incontinence (GSI) with urethral hypermobility. The specific aims were to determine the exact ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20051
更新日期:2005-01-01 00:00:00
abstract:AIMS:We report the success rate and complications rate of combined ultralateral anterior Colporrhaphy plus Tension-free Vaginal Tape (TVT-O) in a long-term (10 year) follow-up prospective survey. METHODS:Patients previously treated for associated stress urinary incontinence (SUI) and cystocele were subjected to annual...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23439
更新日期:2018-03-01 00:00:00
abstract::Of 120 men with benign prostatic enlargement who were evaluated urodynamically, 60 had stable bladders, with (n=30) and without (n=30) outlet obstruction (OO), whereas 60, both obstructed (n=30) and unobstructed (n=30), had detrusor instability (DI). The unstable bladders, wither in the absence or presence of OO, alwa...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(sici)1520-6777(1998)17:5<473::aid-nau3>3.
更新日期:1998-01-01 00:00:00
abstract::We reviewed bladder contraction evolution after sacral anterior root stimulator implantation in thirty patients operated on from 1984 to 1991. Two patients underwent a complete denervation with a reinnervation within a maximal time of seventeen months. One patient underwent a lesion, like a neuropraxia with a complete...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930120514
更新日期:1993-01-01 00:00:00
abstract::It is well known that urethane is a suitable anesthetic for acute studies and has been extensively recommended for investigations related to micturition physiology. This is mainly because of the capability of urethane anesthesia to spare reflex micturition as well as its easily established long-lasting and stable anes...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(sici)1520-6777(2000)19:1<87::aid-nau9>3.0
更新日期:2000-01-01 00:00:00
abstract:AIM:To evaluate the benefits of a newly established checklist form of behavioral therapy for overactive bladder (OAB). METHODS:Of a total of 180 patients suffering eight or more micturitions, two or more nocturia, seven or more urgency, or four more urinary urgency incontinence (UUI) episodes per day according to a 3-...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.23974
更新日期:2019-04-01 00:00:00
abstract:AIM:The aim of the study was to assess correlations between body parameters and bladder capacity in healthy schoolboys and schoolgirls. On the basis of those anthropometric data functional bladder capacity (FBC) in children was estimated. MATERIALS AND METHODS:The questionnaires were sent to 1,055 parents of children ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20123
更新日期:2006-01-01 00:00:00