Abstract:
:The International Continence Society Benign Prostatic Hyperplasia Study (ICS-BPH) was devised in response to the perceived underutilization of urodynamics in the diagnosis of benign prostatic obstruction (BPO), together with the apparent reliance on symptoms alone when selecting patients for invasive therapies, despite evidence that lower urinary tract symptoms (LUTS) had poor diagnostic specificity for BPO. The ICS-BPH Study is an international multicenter study employing a wide-ranging patient-completed questionnaire, with questions on symptoms, bothersomeness, quality of life, and sexual function. In addition, each patient underwent multiple urine flow studies and standardized urodynamic investigations (phase I). Phase II was an observational assessment of outcome following a range of treatments: conservative, medical, and surgical. Phase III included data from randomized controlled trials involving a wide range of therapies. One thousand, two hundred and seventy-one patients (mean age, 66 years) were included in phase I from 12 countries: 18% of patients were unobstructed, 22% mildly obstructed, and 60% obstructed on pressure flow studies; 83% of patients performed at least two flow studies. The ICS-BPH Study will allow definitive statements to be made concerning the diagnostic potential of a wide range of LUTS, and will define the place of urine flow studies, describe patients who will need pressure flow studies prior to invasive treatment, and identify those likely to experience an adverse outcome. Although an aim of the study is to produce a diagnostic symptom score, there is considerable doubt as to whether this can be achieved where aging and a variety of lower urinary tract dysfunctions often coexist.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
Abrams P,Donovan JL,de la Rosette JJ,Schäfer Wsubject
Has Abstractpub_date
1997-01-01 00:00:00pages
79-91issue
2eissn
0733-2467issn
1520-6777journal_volume
16pub_type
杂志文章abstract:AIMS:We investigated the role of transient receptor potential ankyrin 1 (TRPA1) channel on the single unit mechanosensitive afferent activities (SAAs) primarily originating from the bladder in the rat. METHODS:Female Sprague-Dawley rats were used. Cystometry with continuous saline instillation was performed after intr...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22449
更新日期:2014-06-01 00:00:00
abstract:AIMS:P(2)X(3) (ATP-gated receptors) in nociceptive neurons of dorsal root ganglion (DRG) participate in transmission of pain signals from the periphery to the spinal cord. However, the role of P(2)X(3) receptors in chronic prostate pain and continued intractable pain remains unclear. MATERIALS AND METHODS:We examined ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21060
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:There is a lack of evidence to assess whether gait functionality can be affected by the condition of the pelvic floor musculature in patients with multiple sclerosis (MS). OBJECTIVE:To evaluate the relationship between pelvic floor functionality and general functional performance, and also their relationshi...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24314
更新日期:2020-03-01 00:00:00
abstract:AIMS:To test the validity of three patient global ratings, satisfaction, perception of improvement, and estimated percent improvement, for measuring outcomes of behavioral treatment for urinary incontinence. METHODS:This report is a secondary analysis of data from three randomized controlled trials testing behavioral ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,meta分析
doi:10.1002/nau.20243
更新日期:2006-01-01 00:00:00
abstract:AIMS:The objective of the study was to compare sacral nerve stimulation (SNS) to pudendal nerve stimulation (PNS) for voiding dysfunction. METHODS:Thirty subjects with voiding dysfunction had a tined lead placed at S3 and a second electrode implanted at the pudendal nerve via a posterior approach. In a blinded, random...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.20174
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Stakeholders from around the world came together to address the unmet needs of underactive bladder (UAB) at the 3rd International Congress for Underactive Bladder. METHODS:The main recommendation from the regulatory working group is a need for a meeting of UAB stakeholders and regulatory agencies i...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23738
更新日期:2018-11-01 00:00:00
abstract:AIMS:Minimum important difference (MID) estimates the minimum degree of change in an instrument's score that correlates with subjective sense of improvement. The aim of this study was to estimate the MID for the Urogenital Distress Inventory (UDI), Incontinence Impact Questionnaire (IIQ) and Overactive Bladder Question...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/nau.21028
更新日期:2011-09-01 00:00:00
abstract:AIMS:A new multidisciplinary clinic specializing in female pelvic medicine and reconstructive surgery (FPMRS) opened at our institution. We sought to assess patient preference in naming this new center, and how readability and word choice informs these preferences. METHODS:We prospectively surveyed patient preference ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24168
更新日期:2020-01-01 00:00:00
abstract::In our hospital, we have followed a group of patients with familial amyloidotic polyneuropathy (FAP), type I. This disease is characterized by a progressive sensitive-motor and autonomic polyneuropathy. The amyloid fibrils of FAP I contain a mutant transthyretin (TTR) molecule. More than 90% of TTR production occurs i...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/(sici)1520-6777(1997)16:1<55::aid-nau7>3.0
更新日期:1997-01-01 00:00:00
abstract::We created gradual partial urethral obstruction in 20 guinea pigs using silver jeweler's jump rings. After 4 or 8 weeks obstruction all animals underwent cystometry and were assigned to one of five urodynamic categories: normal, high pressure voiding, unstable, low compliance, or decompensated. After sacrifice, the co...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930120607
更新日期:1993-01-01 00:00:00
abstract::Anticholinergics are commonly used for the treatment of frequency, urgency, and urge incontinence in women. Alpha-blockers have been shown to have a modulating effect on bladder smooth muscle but are not commonly used clinically for this indication. To evaluate the clinical effectiveness of each treatment as well as t...
journal_title:Neurourology and urodynamics
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1520-6777(1998)17:1<31::aid-nau6>3.0
更新日期:1998-01-01 00:00:00
abstract::The vaginal vestibule has not been the subject of a dedicated journal article. Recent terminology has suggested its division into anterior and posterior components. The case for this division has not yet been assessed. Both components extend laterally from the hymen to the junction with the labia minora. The posterior...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23064
更新日期:2017-04-01 00:00:00
abstract:AIMS:Prostate cancer is the most frequently diagnosed male cancer and urinary incontinence represents a major consequence following surgery. Penile compression clamps (PCCs) which externally occlude the urethra may be used to manage the incontinence. Despite potential complication of PCCs, such as deformation-inflicted...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23172
更新日期:2017-08-01 00:00:00
abstract::The aim of the study was to determine the contribution of intra-abdominal pressure transmission to urinary continence in the female. Five patients with genuine stress incontinence (GSI) were studied. Pressure transmission was measured in equivalent positions inside and outside the urethra and bladder during the Intrav...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930140406
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To compare intermittent catheterization, sling mobilization, and sling transection for treatment of urinary retention after mid-urethral sling surgery. METHODS:Data registered in the Norwegian Female Incontinence Registry from 1998 to 2013 were analyzed in this cohort study to compare subjective and objectiv...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23046
更新日期:2017-04-01 00:00:00
abstract:AIMS:The fall rate in urgency urinary incontinence (UUI) and mixed UI (MUI) older women is higher when compared with that of continent women. One hypothesis is that a strong desire to void (SDV) could alter gait parameters and therefore increase the risk of falls. The aim of this study was to investigate and compare th...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24234
更新日期:2020-02-01 00:00:00
abstract:AIMS:In the bladder, ATP is an important signaling molecule, which is released by bladder stretch and acid. We hypothesized that ATP might play a unique role in patients with OAB, characterized by low bladder volumes at first desire to void (FDV) and maximal cystometric capacity (MCC) and symptoms of frequency/urgency ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22344
更新日期:2013-09-01 00:00:00
abstract:AIMS:To provide a clinical view and interpretation on the methods for analysis of incontinence in patients with overactive bladder. METHODS:Results are analyzed using the total number of incontinence episodes in a 3-day diary period, using fixed and random effect Poisson regression models to calculate ratio of event r...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.22787
更新日期:2016-08-01 00:00:00
abstract:AIMS:The primary aim of this prospective study was to examine the correlations between "The International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF)" score and urodynamic findings in patients with urge incontinence. In addition, we aimed to observe the alterations of these parameters with antimusca...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20389
更新日期:2007-01-01 00:00:00
abstract::A newly revised operation for controlling spasticity in cerebral palsy patients, selective dorsal rhizotomy (SDR), has the potential to affect bladder function. The goal of this multidisciplinary study is to investigate the potential change in bladder function by characterizing and comparing pre- and post-operative sy...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930140110
更新日期:1995-01-01 00:00:00
abstract:AIMS:Given the relative frequency of lower urinary tract dysfunction (LUTD) after major pelvic surgery, the main question for this debate is: "Should we [actively] screen for LUTD after major pelvic surgery," with the intention to treat and improve patient care. METHODS:The discussants selected relevant papers from a ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.22218
更新日期:2012-03-01 00:00:00
abstract:AIM:To determine the importance and contribution of compliance in a pelvic muscle exercise program as a factor in reducing the severity of urinary stress incontinence amongst Chinese women. METHODS:Two hundred fourteen women presenting with urinary stress incontinence who agreed to undertake a program of pelvic muscle...
journal_title:Neurourology and urodynamics
pub_type: 临床试验,杂志文章
doi:10.1002/nau.10110
更新日期:2003-01-01 00:00:00
abstract:AIMS:No one has assessed urodynamic studies (UDS) to determine those steps that elicit the greatest anxiety, distress, and pain in children. We sought to systematically evaluate a child's UDS experience to mollify these reactions. METHODS:Prospective study involving children aged ≥5 undergoing UDS over a 6-month perio...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24339
更新日期:2020-04-01 00:00:00
abstract:AIMS:Lower urinary tract symptoms (LUTS) are common in the aging population. LUTS cause profoundly negative impacts on their quality of life. Pathophysiology of LUTS is multifactorial, and recently, bladder ischemia and metabolic syndrome have been suggested as etiological factors. To evaluate chronic hyperlipidemia on...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20843
更新日期:2010-09-01 00:00:00
abstract:AIMS:We report the success rate and complications rate of combined ultralateral anterior Colporrhaphy plus Tension-free Vaginal Tape (TVT-O) in a long-term (10 year) follow-up prospective survey. METHODS:Patients previously treated for associated stress urinary incontinence (SUI) and cystocele were subjected to annual...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23439
更新日期:2018-03-01 00:00:00
abstract:INTRODUCTION:The following is a report on the proceedings of the 2019 International Consultation on Incontinence-Research Society nocturia think tank (NTT). OBJECTIVES:The objectives of the 2019 NTT were as follows: (a) to evaluate the role of urothelium in the pathophysiology of nocturia; (b) to determine whether noc...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.24274
更新日期:2020-07-01 00:00:00
abstract:AIMS:We sought to determine whether somatic lumbar nerve transfer to the pelvic nerve's anterior vesical branch after sacral decentralization for detrusor muscle reinnervation also leads to aberrant innervation of the bladder outlet. METHODS:Twenty-six female mongrel hound dogs underwent transection of sacral dorsal a...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24217
更新日期:2020-01-01 00:00:00
abstract:AIMS:While the effect of different types of incontinence on the quality of life (QoL) has been clearly documented, the information about the impact of incontinence severity on QoL in women is lacking. Therefore, we investigated whether increasingly severe degrees of incontinence were linearly correlated with poorer QoL...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23568
更新日期:2018-08-01 00:00:00
abstract:AIMS:Phelan-McDermid syndrome (PMD) is a congenital syndrome caused by a deletion on chromosome 22q13.3. About 600 cases have been identified worldwide. PMD is characterized by neonatal hypotonia, moderate/severe intellectual impairment, impaired expressive language, and typical dysmorphic features. Psychological sympt...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24197
更新日期:2020-01-01 00:00:00
abstract:AIMS:Voiding dysfunction due to dysfunctional voiding (DV) and poor relaxation of the external sphincter (PRES) are commonly found among adult women with lower urinary tract symptoms (LUTS) during videourodynamic study (VUDS). This study analyzed the VUDS characteristics of DV and PRES in female voiding dysfunction. M...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23263
更新日期:2017-11-01 00:00:00