ICI-RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia?

Abstract:

INTRODUCTION:The following is a report on the proceedings of the 2019 International Consultation on Incontinence-Research Society nocturia think tank (NTT). OBJECTIVES:The objectives of the 2019 NTT were as follows: (a) to evaluate the role of urothelium in the pathophysiology of nocturia; (b) to determine whether nocturia is a circadian disorder; (c) to discuss the role of melatonin in nocturia; (d) to consider ambulatory urodynamic monitoring in evaluating patients with nocturia; (e) to explore studies of water handling in human compartments utilizing heavy water; and (f) to explore whether basic science is the key to understanding the treatment options for diminished bladder capacity in patients with nocturia. METHODS:A compendium of discussions of the role of experimental science in understanding the pathophysiology of nocturia is described herein. RESULTS AND CONCLUSIONS:Translational science will play an increasing role in understanding the pathophysiology of nocturia, which may result in improved treatment strategies.

journal_name

Neurourol Urodyn

authors

Vahabi B,Jabr R,Fry C,McCloskey K,Everaert K,Agudelo CW,Monaghan TF,Rahnama'i MS,Panicker JN,Weiss JP

doi

10.1002/nau.24274

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

S88-S95

eissn

0733-2467

issn

1520-6777

journal_volume

39 Suppl 3

pub_type

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