Abstract:
:Of 120 men with benign prostatic enlargement who were evaluated urodynamically, 60 had stable bladders, with (n=30) and without (n=30) outlet obstruction (OO), whereas 60, both obstructed (n=30) and unobstructed (n=30), had detrusor instability (DI). The unstable bladders, wither in the absence or presence of OO, always showed a greater mechanical capability. In particular, compared to the stable bladders, the unstable ones not only had greater strength, but also showed a higher maximum shortening velocity (as well as a shorter opening time and not significantly higher internal work). In the obstructed unstable series, compared to the obstructed stable one, such findings paralleled a more severely increased urethral impedance, which suggests that a functional "compensatory" response to a greater OO was facilitated. All such data were hypothesized to result from microstructural changes yielding an easier electrical coupling between the detrusor smooth muscle cells and hence both a state of DI and better synchronized (thus, stronger and faster) micturition contractions. At least, the latter would be the case should there be no heavy bladder collagenosis upsetting the spread of the depolarization wave.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
Cucchi Adoi
10.1002/(sici)1520-6777(1998)17:5<473::aid-nau3>3.subject
Has Abstractpub_date
1998-01-01 00:00:00pages
473-81issue
5eissn
0733-2467issn
1520-6777pii
10.1002/(SICI)1520-6777(1998)17:5<473::AID-NAU3>3.journal_volume
17pub_type
杂志文章abstract:AIMS:Uncoordinated reflex contractions of the external urethral sphincter (EUS) are a major component of voiding dysfunction after neurologic injury. Patterned stimulation of sacral afferent pathways can reduce abnormal EUS reflexes after acute spinal cord injury (SCI); however, effectiveness following chronic SCI is u...
journal_title:Neurourology and urodynamics
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doi:10.1002/nau.22276
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journal_title:Neurourology and urodynamics
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journal_title:Neurourology and urodynamics
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journal_title:Neurourology and urodynamics
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
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journal_title:Neurourology and urodynamics
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journal_title:Neurourology and urodynamics
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doi:10.1002/nau.23028
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20051
更新日期:2005-01-01 00:00:00
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journal_title:Neurourology and urodynamics
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abstract:AIMS:The biomechanical properties of length adaptation and adjustable preload have been previously identified in detrusor smooth muscle in animal models. This in vitro study aims to show that human detrusor smooth muscle exhibits length adaptation and adjustable preload tension which could play an important role in bot...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22820
更新日期:2016-09-01 00:00:00
abstract:AIMS:Vaginal distention (VD) is a validated model of birth-related trauma in rats. Recently a mouse VD model was reported. Our study was originally conducted to evaluate the impact of age on VD in mice. This manuscript describes the study and reports on the lack of reproducibility of VD models in mice. METHODS:We util...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23886
更新日期:2019-02-01 00:00:00
abstract:INTRODUCTION:Hydrodistention (HD) has been utilized as a diagnostic and therapeutic tool in patients with refractory and diverse pelvic floor symptoms, including bladder pain with or without irritative bladder symptoms such as urinary urgency and urinary frequency. We sought to determine whether we could better define ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20200
更新日期:2005-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
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更新日期:2012-04-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
abstract:AIMS:The prevalence rate of severe fecal incontinence (FI) in adults with spina bifida (SB) is high. The physiological basis of FI in SB has not been clearly established, which contributes to inadequate care. The aim was to better characterize a large cohort of adults with special consideration of anorectal physiology....
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
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更新日期:2018-03-01 00:00:00