Abstract:
AIMS:The aim of this study was to resolve the paradox as to whether magnetic stimulation of sacral nerve roots results in contraction or suppression of the bladder, in both normal individuals and patients with spinal cord injury (SCI). MATERIALS AND METHODS:Seven males with complete SCI and neurogenic detrusor overactivity (NDO) and five normal males were investigated. Bladder capacity and maximum cystometric capacity were determined, respectively, in these groups. Magnetic stimulation was applied to sacral nerve roots using a multi-pulse magnetic stimulator and coil. Stimulation was applied at half capacity, near-full capacity, and during NDO or voiding (in normal individuals). Single and intermittent bursts of stimulation were applied. RESULTS:Neither single nor intermittent bursts of magnetic stimulation of the sacral nerve roots resulted in significant bladder pressure rises. Occasionally, following cessation of the magnetic stimulation bladder contractions were seen in patients with NDO. These contractions had an unpredictable and variable latency. As previously reported, magnetic stimulation suppressed NDO in patients with SCI, and suppressed voiding in normal individuals. CONCLUSIONS:Bladder contractions are occasionally observed in patients with NDO following withdrawal of stimulation. This phenomenon hypothetically arises as a result of removal of the bladder suppression provided by magnetic stimulation, rather than direct motor pathway stimulation (as has been reported by others). The ability of sacral magnetic stimulation to suppress detrusor contractions is reaffirmed.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
Bycroft JA,Craggs MD,Sheriff M,Knight S,Shah PJdoi
10.1002/nau.20009subject
Has Abstractpub_date
2004-01-01 00:00:00pages
241-5issue
3eissn
0733-2467issn
1520-6777journal_volume
23pub_type
临床试验,杂志文章abstract:INTRODUCTION:Turkish Continence Society aimed to analyze how overactive bladder (OAB) is being managed in routine practice by the urologists in Turkey. MATERIAL AND METHODS:Fourteen urology departments were randomly selected to represent the whole population in this multicenter study. An online data entry and storage ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,多中心研究
doi:10.1002/nau.24079
更新日期:2019-11-01 00:00:00
abstract:AIMS:Individuals with spinal cord injury or neurological disorders may develop bladder contractions at low volumes (neurogenic detrusor overactivity), which can lead to significant health problems. Present devices can inhibit unwanted contractions through continuous electrical stimulation of sensory nerves, but do not ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20204
更新日期:2006-01-01 00:00:00
abstract:AIMS:Chronic inflammation has been implicated in the development of overactive bladder (OAB) and interstitial cystitis/bladder pain syndrome (IC/BPS). An elevation of C-reactive protein (CRP) has been associated with chronic inflammation and lower urinary tract symptoms. This study aims to elucidate the association bet...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20938
更新日期:2011-03-01 00:00:00
abstract:AIMS:Percutaneous tibial nerve stimulation (PTNS) is an effective neuromodulation therapy for treating overactive bladder (OAB). The therapeutic effects are achieved by repeatedly applying electrical stimulation through a percutaneous needle electrode that is used to target the tibial nerve (TN). Anatomical studies ind...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23323
更新日期:2018-02-01 00:00:00
abstract:AIMS:To evaluate if pelvic floor innervation differed in patients with rectocele compared to control subjects and to assess if nerve fiber density of the rectovaginal wall correlated to the clinical presentation of rectocele. METHODS:Biopsies from 24 female patients with posterior vaginal wall prolapse stage II (ICS-c...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20249
更新日期:2006-01-01 00:00:00
abstract:AIM:To characterize purinergic signaling in overactive bladder (OAB). METHODS:Mucosal biopsies were taken by flexible cystoscopy from patients with storage symptoms referred to Urology Departments of collaborating hospitals. Immunohistochemistry (n = 12) and Western blot analysis (n = 28) were used to establish the qu...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24322
更新日期:2020-03-01 00:00:00
abstract::Detrusor hyperreflexia (DH) is frequently found in patients with benign prostatic hypertrophy (BPH) and persists in 30-50% of patients after successful removal of bladder neck obstruction by transurethral prostatectomy (TUR-P) or surgical enucleation of the prostate. It would be beneficial for surgeons to be able to i...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(sici)1520-6777(2000)19:3<233::aid-nau4>3.
更新日期:2000-01-01 00:00:00
abstract:AIMS:To investigate the role of beta-adrenoceptor subtypes in mediating relaxation of the pig bladder trigonal muscle in vitro. MATERIALS AND METHODS:Longitudinal strips of trigonal muscle were isolated, and the mucosa and serosa removed. Tissues were precontracted with KCl, and beta-adrenoceptor agonists (isoprenalin...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.10130
更新日期:2003-01-01 00:00:00
abstract:AIM:To compare the urethral sphincter morphology and levator hiatal dimensions between white and black premenopausal nulliparous asymptomatic women using 3D/4D translabial ultrasonography. METHODS:Nulliparous black and white women were recruited in a tertiary gynecological center. All women were completely asymptomati...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21181
更新日期:2012-04-01 00:00:00
abstract::The aim of the present study was to determine to what extent adult rats can produce new contracting bladder muscle and to see if such newly formed bladder tissue possesses characteristic mechanical properties or whether the ability to recover mechanically is so pronounced that the prehistory of the bladder is unimport...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1020
更新日期:2001-01-01 00:00:00
abstract:AIMS:Overactive bladder (OAB), characterized by urinary urgency, with or without incontinence, and urinary frequency and nocturia, has a significant impact on patients' lives. Given the social context inherent in OAB, the purpose of this study was to identify issues faced by OAB family members. METHODS:Incontinent OAB...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20705
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:As increasing evidence suggest that α(1)-blockers prevent benign prostatic hyperplasia related overactive bladder and nocturia in the human, we investigated the effects of silodosin and naftopidil on hypertension-related bladder dysfunction in the spontaneously hypertensive rat (SHR) model. MATERIALS AND METHO...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22297
更新日期:2013-04-01 00:00:00
abstract:AIMS:While the effect of different types of incontinence on the quality of life (QoL) has been clearly documented, the information about the impact of incontinence severity on QoL in women is lacking. Therefore, we investigated whether increasingly severe degrees of incontinence were linearly correlated with poorer QoL...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23568
更新日期:2018-08-01 00:00:00
abstract:AIMS:To measure transient receptor potential vanilloid type 1 (TRPV1) signaling in human bladder urothelial cells (BUC) from non-neurogenic overactive bladder (OAB) patients and control subjects (NB) BUC. MATERIALS AND METHODS:Primary BUC cell cultures were derived from cystoscopic biopsies from two OAB and two NB sub...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21045
更新日期:2011-04-01 00:00:00
abstract:AIMS:Lower urinary tract dysfunctions (LUTD) are very common in Multiple Sclerosis (MS), have a significant social impact, while the organic impact is discussed. We studied urinary complications and their risk factors in our cohort of MS patients, in order to improve the management of LUTD in MS. METHODS:Between 2004 ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22495
更新日期:2015-01-01 00:00:00
abstract:AIMS:Prompted by patients' changing perceptions of transvaginal mesh, this study examines how mesh has been reported in the news following the 2011 US Food and Drug Administration (FDA) updated notification about the use of mesh in the treatment of pelvic organ prolapse. METHODS:Two national newspaper databases were q...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22923
更新日期:2017-02-01 00:00:00
abstract:AIMS:The aim of our study was to analyze whether uroflowmetry parameters are helpful in diagnosing overactive bladder (OAB). The working hypothesis was that the flow curves of patients with OAB symptoms would appear as a sharp peak flow rate with a short duration and high amplitude, lasting only for a short period duri...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22898
更新日期:2017-01-01 00:00:00
abstract:AIMS:Urgency is a key symptom in the diagnosis of overactive bladder (OAB), yet its definition and measurement are subject to continuing debate whether urinary urgency is a pathologic sensation or an intensification of normal desire to pass urine. The objective of this research was to explore the concept of urgency amo...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21242
更新日期:2012-04-01 00:00:00
abstract:AIMS:The Urogenital Distress Inventory (UDI-6) and Incontinence Impact Questionnaire (IIQ-7) assess symptom distress and the impact on daily life of urinary incontinence. The UDI-6 has not been validated before in males. Our aim was to validate the UDI-6 and IIQ-7 in Dutch men and women. METHODS:The translation to Dut...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22496
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Widely accepted consensus terminology and calculations of detrusor contractility in females do not exist but may be useful. We report the output of a proposal session at the International Consultation on Incontinence Research Society meeting 2019, addressing the title topic. METHODS:Three formal presentat...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.24260
更新日期:2020-07-01 00:00:00
abstract:AIMS:To identify clinical and urodynamic factors leading to spontaneous voiding in men with detrusor underactivity (DU) and suspected bladder outlet obstruction who underwent an outlet de-obstruction procedure. METHODS:We identified 614 men who underwent an outlet procedure at our institution from 2005 to 2014. Men we...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24122
更新日期:2019-11-01 00:00:00
abstract:AIMS:The primary aim of this prospective study was to examine the correlations between "The International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF)" score and urodynamic findings in patients with urge incontinence. In addition, we aimed to observe the alterations of these parameters with antimusca...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20389
更新日期:2007-01-01 00:00:00
abstract:AIM:The aim was to describe the characteristics of young adult women who report urinary incontinence (UI), the types of UI they experience, the strategies they use or consider important for managing UI, and help-seeking behavior. METHODS:Data were from the 1989-1995 Australian Longitudinal Study on Women's Health coho...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24483
更新日期:2020-11-01 00:00:00
abstract:AIMS:To investigate the functional outcome after supratrigonal cystectomy and augmentation ileocystoplasty in adult patients with refractory neurogenic lower urinary tract dysfunction (NLUTD). METHODS:Retrospective follow-up investigation in a single spinal cord injury rehabilitation center. In 29 patients, urodynamic...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22709
更新日期:2016-02-01 00:00:00
abstract:AIMS:To test the validity of three patient global ratings, satisfaction, perception of improvement, and estimated percent improvement, for measuring outcomes of behavioral treatment for urinary incontinence. METHODS:This report is a secondary analysis of data from three randomized controlled trials testing behavioral ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,meta分析
doi:10.1002/nau.20243
更新日期:2006-01-01 00:00:00
abstract:AIM OF THE STUDY:To estimate the prevalence and 5-year incidence of lower urinary tract symptoms (LUTS) after the first delivery and to evaluate the impact of pregnancy per se and delivery per se on long-lasting symptoms. MATERIALS AND METHODS:A longitudinal cohort study of 305 primiparae questioned a few days, 3 mont...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.2198
更新日期:2002-01-01 00:00:00
abstract:AIM:Here, we present the clinical presentation and surgical outcomes of women with symptomatic urethral prolapse presenting to our institution over 20 years, and seek to provide treatment recommendations for management of symptomatic urethral prolapse and caruncle. METHODS:A retrospective review of medical records fro...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23232
更新日期:2017-11-01 00:00:00
abstract:AIM:To evaluate the association between lower urinary tract symptoms (LUTS) and incidental falls and fear of falling. METHODS:We used data obtained from the 2011 Korean Community Health Survey (KCHS) conducted between August and October 2011 in South Korea. The survey was carried out to estimate patterns of disease pr...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23345
更新日期:2018-02-01 00:00:00
abstract:AIMS:The urethral retro-resistance pressure (URP) is a retrograde urethral pressure profile measured by a new urodynamic measurement system.1GYNECARE MoniTorr Urodynamic Measurement System (ETHICON, Inc., Somerville, NJ). URP is the pressure required to achieve and maintain an open sphincter. This clinical investigatio...
journal_title:Neurourology and urodynamics
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1002/nau.20010
更新日期:2004-01-01 00:00:00
abstract:AIMS:Once-daily extended-release (XR) trospium chloride has been evaluated for the treatment of overactive bladder syndrome (OAB) in two 12-week randomized, double-blind, placebo-controlled studies. This pooled analysis of the 9-month open-label extensions to these studies evaluated the long-term efficacy and tolerabil...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21000
更新日期:2011-09-01 00:00:00