Abstract:
Purpose:To compare the cervical cancer treatment outcome and toxicities between two different institutions. Material and methods:We analysed the clinical outcome of cervical cancer patients treated at two different centres from January 2015 to December 2016. Centre A treated 72 patients by external beam radiotherapy (EBRT) to a dose of 45 Gy in 25 fractions followed by intracavitary brachytherapy (ICBT) 6.5 Gy × 4 fractions and centre B treated 89 patients by EBRT to a dose of 50.4 Gy in 28 fractions followed by ICBT 9 Gy × 2 fractions. The local control, distant metastases and treatment toxicities were compared. Results:The median follow-up in centre A was 12 months and in centre B was 18 months. The median overall treatment time in centre A was 52 days and in centre B was 61 days. The mean equieffective doses in 2 Gy (EQD2) for high risk target volume (CTVHR) and point A in centre A were 84.59 and 64.5 Gy, respectively. The mean EQD2 for point A in centre B was 78.5 Gy. One patient out of 72 (1.38%) had local recurrence in centre A and five patients out of 89 (5.6%) had local recurrence in centre B. Local control in centre A was 98.6% and in centre B was 94.3%. The local recurrence rate was higher in centre B but it was not statistically significant (p = 0.15). One patient developed brain metastasis in centre B. One patient developed grade 3 proctitis in centre A. Conclusions:A high dose rate brachytherapy fractionation schedule of 6.5 Gy × 4 fractions over 2 days for CTVHR is associated with reduced overall treatment time, a slightly higher local control rate and lesser dose to OARs compared to 9 Gy × 2 fractions given one week apart to point A.
journal_name
J Contemp Brachytherapyjournal_title
Journal of contemporary brachytherapyauthors
Ravindran E,Kumar M,Gururajachar JM,Thangaraj Rdoi
10.5114/jcb.2019.88582subject
Has Abstractpub_date
2019-10-01 00:00:00pages
423-427issue
5eissn
1689-832Xissn
2081-2841pii
37937journal_volume
11pub_type
杂志文章abstract:Purpose:We present a case report of treatment using interstitial and surface high-dose-rate (HDR) brachytherapy for cutaneous squamous cell carcinoma (SCC) involving the interspace of the third and fourth digits. The patient refused two-ray amputation and the lesion was not amenable for external beam radiation therapy ...
journal_title:Journal of contemporary brachytherapy
pub_type:
doi:10.5114/jcb.2020.92408
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:While there are several reports of prostate multisector dosimetry data obtained from CT or MRI scans performed at intervals ranging from 14-70 days after prostate brachytherapy (PB), there are no reports on multisector dosimetry performed in the immediate post-implant period. This study was undertaken to determ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2014.42023
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:To report on preliminary results of a prospective study on MRI-assisted cervix cancer brachytherapy pre-planning. MATERIAL AND METHODS:In six locally advanced cervix cancer patients, five days before the first brachytherapy fraction, tandem & ring applicator was inserted under para-cervical anaesthesia, MRI pe...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:
更新日期:2009-10-01 00:00:00
abstract::Over the last twenty years major software and hardware developments in brachytherapy treatment planning, intraoperative navigation and dose delivery have been made. Image-guided brachytherapy has emerged as the ultimate conformal radiation therapy, allowing precise dose deposition on small volumes under direct image v...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章,评审
doi:10.5114/jcb.2010.16920
更新日期:2010-09-01 00:00:00
abstract:Purpose:Soft tissue sarcoma (STS) is rare but aggressive neoplasm. Interstitial brachytherapy (ISBT) alone or combined with external beam radiotherapy (EBRT) as post-operative treatment improves loco-regional (LRC) and distant control. Material and methods:Out of twenty-nine non-metastatic STS (lower limb 64%) patient...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2018.78994
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:A report of preliminary results and toxicity profiles using image-guided brachytherapy (IGBT) combined with whole pelvic intensity-modulated radiation therapy (WP-IMRT) for locally advanced cervical cancer. MATERIAL AND METHODS:Fifteen patients with locally advanced cervical cancer were enrolled into the study...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2013.34338
更新日期:2013-03-01 00:00:00
abstract:Purpose:Inadequate procedural training is of increasing concern in resident training, especially in prostate brachytherapy (PB). Transperineal rectal spacer placement (TRSP) requires many of the same proficiencies as PB. This work describes the assessment of teaching techniques focusing on developing critical competenc...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2019.90984
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:In the study we present the initial results of palliative treatment using combined methods of HDR-BT and stent insertion in patients with advanced esophagus cancer. MATERIAL AND METHODS:Fifty patients were treated in the Great Poland Cancer Center using HDR-BT between June 2001 and December 2005 and they were ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:
更新日期:2009-03-01 00:00:00
abstract:PURPOSE:To evaluate the treatment outcomes with high-dose-rate (HDR) interstitial brachytherapy (HDR-BRT) in head and neck cancers (HNC). MATERIAL AND METHODS:Fifty-eight patients with HNC as per American Joint Committee on Cancer (AJCC) TNM staging criteria were analyzed retrospectively between 2008 and 2015. Forty-t...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2017.67147
更新日期:2017-04-01 00:00:00
abstract::The aim of this study is to report the use of ruthenium brachytherapy as an adjunctive treatment in the management of an intraocular extension of the conjunctival squamous cell carcinoma (SCC). In 2013, a 73-year-old man presented with a tumor blocking the angle and infiltrating corneal endothelium. The patient was tr...
journal_title:Journal of contemporary brachytherapy
pub_type:
doi:10.5114/jcb.2018.75603
更新日期:2018-04-01 00:00:00
abstract:PURPOSE:To evaluate whether Co-60 is equivalent to Ir-192 for HDR cervical brachytherapy, through 3D-DVH dose comparisons in standard and optimised plans. Previous studies have only considered 2D dosimetry, point dose comparisons or identical loading. Typical treatment times and economics are considered. MATERIAL AND ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2012.27952
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To outline the evolution of computerized brachytherapy treatment planning in the United States through a review of technological developments and clinical practice refinements. MATERIAL AND METHODS:A literature review was performed and interviews were conducted with six participants in the development of compu...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章,评审
doi:10.5114/jcb.2014.43131
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:To explore patterns of time to failure in men receiving high doses of permanent seed brachytherapy with or without external beam radiation therapy as a function of risk status. MATERIAL AND METHODS:Two thousand two hundred and thirty four patients were treated with prostate brachytherapy with median follow up ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2013.39210
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:This study investigates the distortion of geometry of catheters and anatomy in acquired U/S images, caused by utilizing various stand-off materials for covering a transrectal bi-planar ultrasound probe in HDR and LDR prostate brachytherapy, biopsy and other interventional procedures. Furthermore, an evaluation ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2011.26472
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:The purpose of this study is to obtain the dosimetric parameters of the new BEBIG (60)Co brachytherapy source following by TG-43U1 recommendation with appropriate electron cutoff energy (0.521 MeV). MATERIAL AND METHODS:The new BEBIG (60)Co brachytherapy source is used to calculate the TG-43U1 parameters. EGSn...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2013.37419
更新日期:2013-09-01 00:00:00
abstract:Purpose:To compare post-implant dosimetrics between intraoperatively built custom-linked (IBCL) seeds and loose seeds (LS) at 24 hours and 1 month by sector analysis, and to evaluate the effect of IBCL seeds with regard to change in dosimetric parameters, in patients with prostate cancer treated with brachytherapy. Ma...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2020.98110
更新日期:2020-08-01 00:00:00
abstract:Purpose:To quantify the reduction of relative displacement between the implanted intracavitary applicator and the patient bony anatomy, due to the use of a hover transport system during the patient transports between the imaging table and the treatment table. Material and methods:The displacement of the applicator ins...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2018.73755
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:To retrospectively compare the potential dosimetric advantages of a multichannel vaginal applicator vs. a single channel one in intracavitary vaginal high-dose-rate (HDR) brachytherapy after hysterectomy, and evaluate the dosimetric advantage of fractional re-planning. MATERIAL AND METHODS:We randomly selected...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2014.47816
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:The incidence of non-melanoma skin cancer (NMSC) has been increasing over the past 30 years. There are different treatment options and surgical excision is the most frequent treatment due to its low rates of recurrence. Radiotherapy is an effective alternative of surgery, and brachytherapy (BT) might be a bette...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章,评审
doi:10.5114/jcb.2016.64112
更新日期:2016-12-01 00:00:00
abstract:Purpose:To report the results of INTERACTS (INTErventional Radiotherapy ACtive Teaching School) consensus conference on sarcoma interventional radiotherapy (brachytherapy). Material and methods:An international board of multidisciplinary experts was invited to a consensus conference on the state-of-the-art of sarcoma ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章,评审
doi:10.5114/jcb.2020.98120
更新日期:2020-08-01 00:00:00
abstract:Purpose:Artificial intelligence (AI) plays a central role in building decision supporting systems (DSS), and its application in healthcare is rapidly increasing. The aim of this study was to define the role of AI in healthcare, with main focus on radiation oncology (RO) and interventional radiotherapy (IRT, brachythera...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章,评审
doi:10.5114/jcb.2020.100384
更新日期:2020-10-01 00:00:00
abstract:Purpose:To evaluate the impact of supplemental external beam radiation therapy (EBRT) prior to permanent prostate brachytherapy on long term urinary, bowel, and erectile function. Material and methods:Patient administered urinary, bowel, and erectile quality of life (QoL) instrument were obtained prior to treatment an...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2017.70763
更新日期:2017-10-01 00:00:00
abstract:Purpose:Skin cancers are the most common human malignancy with increasing incidence. Currently, surgery is standard of care treatment for non-melanoma skin cancers. However, brachytherapy is a growing modality in the management of skin cancers. Therefore, we aimed to assess the outcome of patients with non-melanoma ski...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2018.75596
更新日期:2018-04-01 00:00:00
abstract:PURPOSE:Dose coverage is crucial for successful treatment in mono-brachytherapy. Since few and very high dose fractions are used, there is an important balance between dwell positioning outside the clinical target volume (CTV) and possible damage on adjacent normal tissue. The purpose of this study was to evaluate the ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2014.45586
更新日期:2014-10-01 00:00:00
abstract:Purpose:To evaluate dose-volume relationships of target volume and critical structures in computed tomography (CT) image-based brachytherapy for head and neck cancer. Material and methods:Thirty-seven patients with mobile tongue, floor of mouth, and base of tongue cancer treated with brachytherapy (post-operative alon...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2017.72581
更新日期:2017-12-01 00:00:00
abstract:Purpose:To evaluate clinical outcomes in patients with localized prostate cancer (LPC) treated with 3D conformal high-dose-rate (HDR) brachytherapy (BT) as monotherapy. Material and methods:From March 2004 to November 2017, 277 men with LPC underwent 3D conformal HDR-BT as monotherapy, with a temporary implant. The do...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2020.101685
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:The standard primary treatment for soft tissue sarcoma (STS) is a wide surgical resection, preceded or followed by radiotherapy. Purpose of this retrospective study was to assess the efficacy of perioperative brachytherapy (BRT) plus postoperative external beam radiation therapy (EBRT) in patients with intermed...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2017.68215
更新日期:2017-06-01 00:00:00
abstract:Purpose:To investigate the differences in prostate-specific antigen (PSA) bounce (PB) after high-dose-rate (HDR-BT) or low-dose-rate (LDR-BT) brachytherapy alone in prostate cancer patients. Materials and methods:Ninety-four patients with localized prostate cancer (T1-T2cN0), age ranged 50-81 years, were treated with ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2018.73786
更新日期:2018-02-01 00:00:00
abstract:Purpose:The aim of this study was to compare short-term oncologic outcomes and toxicity of focal or partial low-dose-rate brachytherapy (focal/partial LDR-BT) with whole gland low-dose-rate brachytherapy (whole LDR-BT) in localized prostate cancer patients. Material and methods:Medical records of eligible patients who...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2020.100374
更新日期:2020-10-01 00:00:00
abstract:Purpose:A feasibility study of 3D volume-based interstitial brachytherapy using thermoplastic polyether ether ketone (PEEK) catheters in advanced cervical cancer MR-based brachytherapy, when MR-compatible applicators are not available. Material and methods:Five cervical cancer patients received EBRT dose of 50 Gy in 2...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2019.86975
更新日期:2019-08-01 00:00:00